Nanotechnology offers many advantages in various fields of science. Recent advances in nanotechnology have proven that nanoparticles acquire a great potential in medical applications. Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. This present review provided a detailed overview of the synthesis, properties and applications of Nanoparticles (NPs) exist in different forms. NPs are tiny & small, ranges from 1 to 100 nm. They are classified into different classes based on their properties, shapes or sizes. The different groups include fullerenes, metal NPs, ceramic NPs, and polymeric NPs. NPs possess unique physical and chemical properties due to their high surface area and nanoscale size. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications. AgNPs play an important role in nanoscience and nanotechnology, particularly in nanomedicine. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications, apart from its antimicrobial activity.