The Egyptian Ministry of Antiquities and the University of Milan collaborate in the protection, preservation and valorisation of the large necropolis surrounding the Mausoleum of the Aga Khan in West Aswan. The first mission has been completed, the second is underway. Director Patrizia Piacentini describes the work and finds from the first mission and the experts from different fields (anthropology, palaeopathology, chemistry, botany, restauration, the computer sciences) that will be deployed during the second phase. Particular emphasis has been given to the historical meaning of the necropolis, in general, and, in particular, of tomb AGH026, which was excavated in 2019. They promise to yield information on the history and international contacts of the population of Aswan during the Late Pharaonic and Ptolemaic-Roman Period. Vicedirector Massimiliana Pozzi Battaglia enumerates some of the particular issues that were encountered from the point of view of conservation and transport. Inside Tomb AGH 026 different conditions were encountered, depending mostly on whether sand had covered a specific spot or not, which conditioned the preservation of the human bodies, cartonnage-making and wooden items and influenced their transportation and storage. Said Mahmoud Abd El-Moneim, General Director of Aswan and Nubia Antiquities Zone and Co-director of the mission at Aga Khan necropolis, widens the scope of the article to address other endangered sites that at present concerns of the Egyptian Ministry of Antiquities. He describes the challenge posed by raising water levels and increased quarrying activity at Kom Ombo, Philae and Bigga, the rock art and palaeolake sites in the Aswan area.