The integration of Building Information Modeling (BIM) with Mechanical, Electrical, and Plumbing (MEP) systems represents a transformative approach to improving efficiency, coordination, and cost-effectiveness in construction projects. This paper explores a comprehensive methodology for BIM and MEP integration, encompassing framework development, data management, and collaboration mechanisms. It highlights the significant benefits such as enhanced project coordination, improved efficiency, and cost reduction while addressing key challenges including technical barriers, cultural and organizational changes, and data security concerns. Solutions such as the development of interoperability standards, middleware technologies, robust data management protocols, and collaborative platforms are discussed. The study underscores the necessity of a multifaceted strategy involving training, change management, and leadership commitment to drive successful implementation. Through detailed analysis and discussion, this paper demonstrates how BIM and MEP integration can lead to more streamlined, cost-effective, and high-quality construction projects.