Risk Factors In Young Adults Research Articles

Metabolic risk factors in young adults infected with HIV since childhood compared with the general population.

AimMetabolic risk factors are poorly documented for the first generation of young adults who have lived with HIV since childhood. We compared their metabolic profile with that of adults of same age from the general population.MethodsWe conducted a cross-sectional analysis of data from two populations: (1) COVERTE (ANRS-CO19), a French national cohort of 18 to 30-year-old patients HIV-infected since childhood, and (2) ENNS, a national cross-sectional population-based household survey on nutrition. Body mass index (BMI), blood pressure, waist circumference, fasting glucose, triglycerides, and HDL-, LDL- and total cholesterol were measured in both studies. Direct standardization on overweight and education level and logistic regression were used to compare the prevalence of metabolic abnormalities between the two populations.ResultsData from 268 patients from COVERTE and 245 subjects from ENNS were analyzed. Tobacco use was similar in both groups. HIV-infected patients had increased mean waist-to-hip ratio and triglycerides to HDL-cholesterol ratio and decreased mean HDL-cholesterol as compared to their counterparts from the general population in both genders. In HIV-infected patients, metabolic syndrome was identified in 13.2% of men (95% confidence interval [CI]: 7.1–19.2) and 10.4% (95% CI: 5.4–15.3) of women versus 10.6% (95%CI: 1.5–19.7) and 1.7% (95%CI: 0–4.1) in subjects from the general population, respectively.ConclusionYoung adults infected with HIV since childhood had a higher prevalence of dyslipidemia and metabolically detrimental fat distribution than adults of same age of the general population, supporting close monitoring for cardiometabolic diseases.

Nutritional status and selected atherosclerotic risk factors in young adults in relation to their birth weight

Nutritional status and selected atherosclerotic risk factors in young adults in relation to their birth weight

Risk Factors for Early‐Onset Ischemic Stroke: A Case‐Control Study

BackgroundRecent studies have shown an increasing prevalence of vascular risk factors in young adults with ischemic stroke (IS). However, the strength of the association between all vascular risk factors and early‐onset IS has not been fully established.Methods and ResultsWe compared 961 patients with a first‐ever IS at 25 to 49 years to 1403 frequency‐matched stroke‐free controls from a population‐based cohort study (FINRISK). Assessed risk factors included an active malignancy, atrial fibrillation, cardiovascular disease, current smoking status, a family history of stroke, high low‐density lipoprotein cholesterol, high triglycerides, low high‐density lipoprotein cholesterol, hypertension, and type 1 and type 2 diabetes mellitus. We performed subgroup analyses based on age, sex, and IS etiology. In a fully adjusted multivariable logistic regression analysis, significant risk factors for IS consisted of atrial fibrillation (odds ratio [OR], 10.43; 95% confidence interval [CI], 2.33–46.77], cardiovascular disease (OR, 8.01; 95% CI, 3.09–20.78), type 1 diabetes mellitus (OR, 6.72; 95% CI, 3.15–14.33), type 2 diabetes mellitus (OR, 2.31; 95% CI, 1.35–3.95), low high‐density lipoprotein cholesterol (OR, 1.81; 95% CI, 1.37–2.40), current smoking status (OR, 1.81; 95% CI, 1.50–2.17), hypertension (OR, 1.43; 95% CI, 1.17–1.75), and a family history of stroke (OR, 1.37; 95% CI, 1.04–1.82). High low‐density lipoprotein cholesterol exhibited an inverse association with IS. In the subgroup analyses, the most consistent associations appeared for current smoking status and type 1 diabetes mellitus.ConclusionsOur study establishes the associations between 11 vascular risk factors and early‐onset IS, among which atrial fibrillation, cardiovascular disease, and both type 1 and 2 diabetes mellitus in particular showed strong associations.

Relation of body composition indexes to cardiovascular disease risk factors in young adults

BackgroundTo evaluate the relationship of body composition indexes with altered metabolic analytical parameters that show higher risk of cardiovascular disease in young adults. Material and methodsA cross-sectional study. Sample of 1351 young adults, different body composition parameters were obtained such as Waist Circumference (WC), Hip Circumference (HC), Body Mass Index (BMI), Body Fat% (BF%), Waist-to-height Ratio (WHtR), and Waist-Hip Ratio (WHR), conicity index (C-Index), body surface area (BSA), abdominal volume index (AVI) and deep abdominal adipose-tissue (AT). Areas under receiver operating characteristic curves (AUCs) and odds ratios for the parameters were analyzed and their optimal cut-offs. Separately a MANOVA was applied to altered metabolic analytical parameters and two body composition indexes (BMI and BSA) and their interaction. ResultsBMI correlate significantly with metabolic analytical parameters (FPG r=0.08, TCh r=0.14, TGL r=0.23, HDL-C r=−0.23, LDL-C r=0.2, UA r=0.22, All P<0.01), BSA correlate with all (All P<0.001) except FPG. BMI and BSA correlate significantly with all metabolic analytical parameters (All P<0.001). The BMI individually predicts the changes of the six metabolic analytical parameters as a set [Wilk's λ=0.89, F(18,1570)=3.4, P<0.0001], but not BSA [Wilk's λ=0.98, F(6,555)=1.4, P=0.18], the interaction between these two indexes (BMI and BSA altered in the same individual) significantly predicts changes of the six metabolic analytical parameters of cardiovascular disease risk [Wilk's λ=0.97, F(6,555)=2.3, P=0.03]. ConclusionsBMI and BSA correlate with cardiovascular disease risk factor. They are superior to WC, WHtR, WHR, BF%, C-index, AVI and AT.

Stroke in young adults: Five new things.

The incidence of stroke in young adults is increasing, mainly driven by an increasing incidence of ischemic stroke in this population. We provide new information that has been recently presented regarding the risk factor prevalence, some specific etiologic causes, and management strategies in ischemic stroke in this population. Recent studies indicate a rapid increase in traditional risk factors in young adults. New information regarding the management of patent foramen ovale in cryptogenic stroke and cervical artery dissection is available. Stroke in young adults is a rapidly growing problem with deep public health implications. There are many areas in this field, which require further research.

Overweight trajectory and cardiometabolic risk factors in young adults

Background/Objectives To assess the association between patterns of overweight over the life course and cardiometabolic risk factors in young adults. Subjects/methods In 1982, the maternity hospitals of Pelotas, a southern city of Brazil, were visited daily and those newborns whose family lived in the urban area of the city were identified (n = 5914) and have prospectively followed for several occasions. Weight and height were measured at every visit. BMI-for-age z-score was calculated using the WHO Child Growth Standards. At 30 years, overweight was defined as a BMI greater than or equal to 25 kg/m2 and obesity by BMI greater than or equal to 30 kg/m2. The participants were divided into eight groups according to the presence of overweight or obesity in childhood, adolescence and adulthood. Blood pressure, random blood glucose, HDL cholesterol, LDL cholesterol triglycerides and fat mass were measured at 30 years. Results From 2219 participants with anthropometric data in childhood, adolescence and adulthood, 25% never had been overweight, whereas 11.6% were overweight in the three periods. Random blood glucose, SBP and DBP were higher among those subjects who were always overweight/obese or only overweight/obese during adolescence and adulthood. The participants who were never overweight/obese or only in childhood or adolescence had a lower cardiometabolic risk profile (higher HDL cholesterol, lower blood pressure, lower random glucose, lower LDL cholesterol) at 30 years. Fat mass captured from 25 to 100% of the association of overweight and obesity trajectory with cardiometabolic risk factors. Conclusions The tracking of overweight/obesity is associated with an adverse cardio metabolic profile and this association is largely mediated by fat mass in adulthood.

Breakfast Consumption and Cardiovascular Risk Factors in University Going Students

Objective: Present research was designed to find association of breakfast skipping with metabolic syndrome risk factors in university going students. In the light of findings of the research project we can control these risk factors in young age before they develop any signs of metabolic disorders in late stages of age. Method: This study included 200 University students. The only condition that implied for these participants was that they should not be under any regular medication. They were instructed to be in overnight fasting before sampling day. Three day dietary record was taken through well-organized questionnaires. Based on the frequency of breakfast eating habits , objects were divided into three groups that are (1) regular breakfast eaters (all 3 days) (2) often breakfast eaters (1 to 2 days) and rare breakfast eaters (all 3 days breakfast skippers). Multiple metabolic risk factors were measured by their respective methods that are BMI, lipid profile, waist circumference, blood pressure, glucose levels. Multiple logistic regression methods were used to evaluate association of breakfast intake with metabolic syndrome risk factors. Results: The number of the subjects called as rare, often and regular breakfast diners were 32(16%), 50 (25%) and 138 (69%). Frequency of male was higher as compared to female regular breakfast eaters. The average of triglycerides, BMI, cholesterol, LDL and systolic blood pressure was significantly higher in rare breakfast eaters as compared to regular eaters (p value <0.001) whereas HDL levels were found lower in rare breakfast eaters as compared to their counterparts. Consequently, breakfast eaters have higher levels of risk factors as compared to regular eaters. The study was designed to evaluate the association between breakfast skipping habit and metabolic syndrome risk factors in young adults. Rare breakfast eaters were found to have more risk factors of metabolic syndromes than regular and often breakfast eaters. Probably, this is the first study in Pakistan to examine associations of breakfast consumption with metabolic syndrome and cardiovascular risk factors in young adults. Future cohort studies using a prospective design could evaluate these findings and investigate potential mechanisms. Conclusively, skipping breakfast is a common behavior among young adults, and is associated with increased risk of metabolic syndrome and other cardiovascular factors. Improvement of habits related to the frequency of breakfast consumption, in the age group under study, could be a valuable, significant and imperative implication to prevent these risk factors.

Four Weeks of Nordic Hamstring Exercise Reduce Muscle Injury Risk Factors in Young Adults.

Ribeiro-Alvares, JB, Marques, VB, Vaz, MA, and Baroni, BM. Four weeks of Nordic hamstring exercise reduce muscle injury risk factors in young adults. J Strength Cond Res 32(5): 1254-1262, 2018-The Nordic hamstring exercise (NHE) is a field-based exercise designed for knee-flexor eccentric strengthening, aimed at prevention of muscle strains. However, possible effects of NHE programs on other hamstring injury risk factors remain unclear. The purpose of this study was to investigate the effects of a NHE training program on multiple hamstring injury risk factors. Twenty physically active young adults were allocated into 2 equal-sized groups: control group (CG) and training group (TG). The TG was engaged in a 4-week NHE program, twice a week, 3 sets of 6-10 repetitions; while CG received no exercise intervention. The knee flexor and extensor strength were assessed through isokinetic dynamometry, the biceps femoris long head muscle architecture through ultrasound images, and the hamstring flexibility through sit-and-reach test. The results showed that CG subjects had no significant change in any outcome. TG presented higher percent changes than CG for hamstring isometric peak torque (9%; effect size [ES] = 0.27), eccentric peak torque (13%; ES = 0.60), eccentric work (18%; ES = 0.86), and functional hamstring-to-quadriceps torque ratio (13%; ES = 0.80). The NHE program led also to increased fascicle length (22%; ES = 2.77) and reduced pennation angle (-17%; ES = 1.27) in biceps femoris long head of the TG, without significant changes on muscle thickness. In conclusion, a short-term NHE training program (4 weeks; 8 training sessions) counteracts multiple hamstring injury risk factors in physically active young adults.

Plasma fatty acid ethanolamides are associated with postprandial triglycerides, ApoCIII, and ApoE in humans consuming a high-fructose corn syrup-sweetened beverage.

Epidemiological and clinical research studies have provided ample evidence demonstrating that consumption of sugar-sweetened beverages increases risk factors involved in the development of obesity, Type 2 diabetes, and cardiovascular disease (CVD). Our previous study demonstrated that when compared with aspartame (Asp), 2 wk of high-fructose corn syrup (HFCS)-sweetened beverages provided at 25% of daily energy requirement was associated with increased body weight, postprandial (pp) triglycerides (TG), and fasting and pp CVD risk factors in young adults. The fatty acid ethanolamide, anandamide (AEA), and the monoacylglycerol, 2-arachidonoyl- sn-glycerol (2-AG), are two primary endocannabinoids (ECs) that play a role in regulating food intake, increasing adipose storage, and regulating lipid metabolism. Therefore, we measured plasma concentrations of ECs and their analogs, oleoylethanolamide (OEA), docosahexaenoyl ethanolamide (DHEA), and docosahexaenoyl glycerol (DHG), in participants from our previous study who consumed HFCS- or Asp-sweetened beverages to determine associations with weight gain and CVD risk factors. Two-week exposure to either HFCS- or Asp-sweetened beverages resulted in significant differences in the changes in fasting levels of OEA and DHEA between groups after the testing period. Subjects who consumed Asp, but not HFCS, displayed a reduction in AEA, OEA, and DHEA after the testing period. In contrast, there were significant positive relationships between AEA, OEA, and DHEA vs. ppTG, ppApoCIII, and ppApoE in those consuming HFCS, but not in those consuming Asp. Our findings reveal previously unknown associations between circulating ECs and EC-related molecules with markers of lipid metabolism and CVD risk after HFCS consumption.

IndEcho study: cohort study investigating birth size, childhood growth and young adult cardiovascular risk factors as predictors of midlife myocardial structure and function in South Asians

IntroductionSouth Asians have high rates of cardiovascular disease (CVD) and its risk factors (hypertension, diabetes, dyslipidaemia and central obesity). Left ventricular (LV) hypertrophy and dysfunction are features of these disorders...

Awareness of Cardiovascular Risk Factors in U.S. Young Adults Aged 18–39 Years

Young adults with hyperlipidemia, hypertension, and diabetes are at increased risk of developing heart disease later in life. Despite emphasis on early screening, little is known about awareness of these risk factors in young adulthood. Data from the nationally representative cross-sectional National Health and Nutrition Examination Survey 2011-2014 were analyzed in 2017 to estimate the prevalence of self-reported awareness of hypercholesterolemia, hypertension, and diabetes in U.S. young adults aged 18-39 years (n=11,083). Prevalence estimates were weighted to population estimates using survey procedures, and predictors of awareness were identified using weighted logistic regression. Among U.S. young adults, the prevalence of hypercholesterolemia, hypertension, and diabetes was 8.8% (SE=0.4%); 7.3% (SE=0.3%); and 2.6% (SE=0.2%), respectively. The prevalence of borderline high cholesterol, blood pressure, and blood glucose were substantially higher (21.6% [SE= 0.6%]; 26.9% [SE=0.7%]; and 18.9% [SE=0.6%], respectively). Awareness was low for hypercholesterolemia (56.9% [SE=2.4%]) and moderate for hypertension and diabetes (62.7% [SE=2.4%] and 70.0% [SE=2.7%]); <25% of young adults with borderline levels of these risk factors were aware of their risk. Correlates of risk factor awareness included older age, insurance status, family income above the poverty line, U.S. origin, having a usual source of health care, and the presence of comorbid conditions. Despite the high prevalence of cardiovascular risk factors in U.S. young adults, awareness remains less than ideal. Interventions that target access may increase awareness and facilitate achieving treatment goals in young adults.

Vitamin D status and cardiometabolic risk factors in young adults in Hong Kong: associations and implications.

Vitamin D deficiency is reportedly common, but we lack data from young adults. Such data are of interest because epidemiological data support vitamin D as a possible risk modulator for diabetes and cardiovascular ('cardiometabolic') disease. Our objectives were to assess vitamin D status (as plasma 25(OH)D concentration) and investigate associations between this and biomarkers of cardiometabolic disease risk in a group of still-healthy young adults in Hong Kong. In this observational study, fasting venous blood was collected from 196 (63 males, 133 females), young (18-26 years) non-smoking, nonobese, consenting adults in good general health. Plasma 25(OH)D was measured by LC-MS/MS. A panel of established cardiometabolic risk factors (HbA1c, plasma glucose, lipid profile, hsCRP) and blood pressure were also measured. Mean (SD) plasma 25(OH)D concentration was 42.1 (13.0), with range 15.7-86.8 nmol/L; 141/196 subjects (72%) had vitamin D deficiency (25(OH)D <50 nmol/L); 13/184 (6.6%) were severely deficient (<25 nmol/L). Inverse association was seen between 25(OH)D and fasting glucose (r=-0.18; p<0.05). Higher HbA1c and TC:HDL-C ratio and lower HDL-C were seen in those with plasma 25(OH)D <25 nmol/L (p<0.05). Vitamin D deficiency was highly prevalent and associated with poorer cardiometabolic risk profile in these young adults. Public health strategies for addressing vitamin D deficiency are needed urgently. These new data provide support for further study on vitamin D deficiency as a modifiable risk factor for cardiometabolic disease and the ameliorative effects of increased vitamin D intake on cardiometabolic disease risk profile of vitamin D-deficient young adults.

Study to determine prevalence of obesity and its association with cardiometabolic risk factors in young adults

Study to determine prevalence of obesity and its association with cardiometabolic risk factors in young adults

Association of Modifiable Risk Factors in Young Adulthood With Racial Disparity in Incident Type 2 Diabetes During Middle Adulthood

In the United States, black individuals are twice as likely to develop type 2 diabetes compared with white individuals, and these disparities are particularly pronounced in young and middle age. Prior studies have identified differences in traditional risk factors that may be associated with racial disparities in diabetes incidence but have not simultaneously adjusted for risk factors measured across multiple domains (eg, the individual and the environment) and updated over time. To determine the relative associations of modifiable biological, neighborhood, psychosocial, socioeconomic, and behavioral factors in young adulthood with the observed racial disparity in diabetes incidence between middle-aged black and white individuals. Black and white men and women from the observational Coronary Artery Risk Development in Young Adults study, aged 18 to 30 years, without diabetes at baseline (1985-1986; N = 4251) were observed through 2015-2016. Sex-stratified multivariable-adjusted Cox proportional hazards modeling, with adjustment for time-updated covariates, was used to estimate risk for incident diabetes. Percent reduction in the β coefficient (the logarithm used to calculate the hazard ratio [HR]) was calculated to compare black to white participants. Self-identified race and factors including biological (eg, fasting glucose, body mass index), neighborhood (racial segregation and tract-level poverty), psychosocial (depressive symptoms), socioeconomic (eg, personal and parental educational attainment, current employment), and behavioral (eg, regular alcohol consumption, smoking) domains. Incident type 2 diabetes mellitus. The mean (SD) age at baseline was 25 (3.6) years, 49% (n = 2066) of the sample was black, and 54% (n = 2304) were women. Over a mean follow-up of 24.5 years, 504 cases of incident diabetes were identified. Using sex-stratified multivariable-adjusted Cox proportional hazards models, black women and men were more likely to develop diabetes than white men and women (black women: HR, 2.86 [95% CI, 2.19-3.72] and risk difference [RD], 89 cases/1000 people [95% CI, 61-117]; black men: HR, 1.67 [95% CI, 1.28-2.17] and RD, 47 cases/1000 people [95% CI, 15-78]) after adjustment for age and center. Biological factors were most strongly associated with the disparity in diabetes risk between black and white individuals for women (percent reduction in β, 112%) and men (percent reduction in β, 86%). There was no longer disparity in diabetes risk between black and white middle-aged adults after adjustment for biological, neighborhood, psychosocial, socioeconomic, and behavioral factors measured over time (HR for women, 0.79 [95% CI, 0.55-1.14]; HR for men, 0.92 [95% CI, 0.62-1.38]). In this cohort study comparing black and white participants, there was a statistically significant increased risk of incident type 2 diabetes among black women and men. However, after adjustment for modifiable risk factors during young adulthood, the disparity was no longer statistically significant.

Prevalence of hypertension and its associated risk factors in young adults attending a tertiary care institute of Nagpur: a cross sectional study

Background: Hypertension is a silent killer and global public health problem. With the advent of globalization affecting the lifestyle of the population, non-communicable diseases like hypertension, diabetes etc. is affecting the young adults (18 to 40 years). The aim of the study was to estimate the prevalence of hypertension and its associated risk factors among young adults (18 to 40 years) attending a tertiary care centre of Nagpur.Methods: This was a cross sectional study on 370 participants of age 18 to 40 years attending the outpatient department of urban health training centre in Nagpur. Data was collected using pretested and pre designed questionnaire and anthropometric measurements were done by standard guidelines. Blood pressure was measured using sphygmomanometer in sitting position. Data was analyzed using Epi info version 7.2. Chi square test/ fisher’s exact test has been used to find the difference between two proportions. Unadjusted odds ratio was calculated for various risk factors studied. Stepwise logistic regression analysis was done to calculate the adjusted odds ratio. Results: The prevalence of hypertension was found to be 23.24%. The prevalence was higher among males (25%) when compared to females (22.3%). Body mass index and waist hip ratio were significantly higher among the hypertensive when compared to normotensive study population (p&lt;0.01). For every one year increase in age, the odds ratio increases by 1.06 (1.02 to 1.09) and the subjects who were overweight were having 2.15 odds of being hypertensive. Conclusions: We found a high prevalence of hypertension among the adults of age group of 18 to 40 years. The population with high body mass index, high waist to hip ratio and age group of 30 to 40 years were found to be associated with hypertension. Early surveillance and prompt treatment forms will help in decreasing the cardiovascular risk of young adults in near future.

Mental Health Problems and Cancer Risk Factors Among Young Adults

Chronic mental health problems often emerge in young adulthood, when adults begin to develop lifelong health behaviors and access preventive health services. The associations between mental health problems and modifiable cancer risk factors in young adulthood are not well understood. In 2016, the authors analyzed 2014 Behavioral Risk Factor Surveillance System data on demographic characteristics, health service access and use, health status, and cancer risk factors (tobacco use, alcohol use, overweight or obesity, physical activity, and sleep) for 90,821 young adults aged 18-39 years with mental health problems (depressive disorder or frequent mental distress) compared to other young adults. Mental health problems were associated with white race; less than a high school education; lower income; being out of work or unable to work; being uninsured (for men only); poor health; previous diagnosis of asthma, skin cancer, or diabetes; and not having a recent checkup. After controlling for demographic characteristics, health service use, and health status, mental health problems among young adults were associated with smoking, binge drinking, inadequate sleep, having no leisure time physical activity, and being overweight or obese (among women only). Cervical cancer screening was not associated with mental health problems after controlling for demographic characteristics, health service use, and health status. Mental health problems in young adulthood were associated with potentially modifiable factors and behaviors that increase risk for cancer. Efforts to prevent cancer and promote health must attend to mental health disparities to meet the needs of young adults.

Improvements in Cardiovascular Risk Factors in Young Adults in a Randomized Trial of Approaches to Weight Gain Prevention.

ObjectiveWeight gain occurs commonly in young adults and increases cardiovascular (CVD) risk. We previously reported that two self-regulation interventions reduced weight gain relative to control. Here we examine whether these interventions also benefit CVD risk factors.MethodsSNAP (Study of Novel Approaches to Weight Gain Prevention) was a randomized trial in 2 academic settings (N=599; 18–35 years; body mass index 21–30 kg/m2) comparing two interventions (Self-Regulation with Small Changes; Self-Regulation with Large Changes) and Control. Small Changes taught participants to make daily small changes (approximately 100 calorie) in intake and activity. Large Changes taught participants to initially lose 5–10 pounds to buffer anticipated weight gains. CVD risk factors were assessed at baseline and 2 years in 471 participants.ResultsAlthough Large Changes was associated with more beneficial changes in glucose, insulin, and HOMA-IR than Control, these differences were not significant after adjusting for multiple comparisons or 2-year weight change. Comparison of participants grouped by percent weight change baseline to 2 years showed significant differences for several CVD risk factors, with no interaction with treatment condition.ConclusionsMagnitude of weight change, rather than specific weight gain prevention interventions, was related to changes in CVD risk factors in young adults.

Actividad física, condición física y factores de riesgo cardio-metabólicos en adultos jóvenes de 18-29 años

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Self-Reported Screen Time is Independently Associated with Cardiometabolic Disease Risk Factors in Young Adults

Research has shown that self-reported screen time is linked to cardiometabolic disease risk factors in children. Whether this association extends to young adults has not been investigated. PURPOSE: To determine the associations between self-reported screen time and individual cardiometabolic disease risk factors in young adults. METHODS: Sixty-six young adults volunteered for the study (mean±SD: age 20.6±1.4 y; BMI 24.3±3.6 kg/m2; body fat 22.7±8.8%; peak oxygen consumption [VO2peak] 45.7±7.7 ml/kg/min). Sedentary behavior and screen time (television viewing, video games and computer games) were self-reported using the Sedentary Behavior Questionnaire. Moderate-to-vigorous physical activity (MVPA) was objectively measured by 7 d of accelerometer wear. Cardiometabolic disease risk factors were measured using standard procedures and included waist circumference, blood pressure, glucose, triglycerides (TG), high-density lipoprotein cholesterol (HDL) and low-density lipoprotein cholesterol (LDL). Body composition was estimated by BOD POD and VO2peak was measured by indirect calorimetry using an incremental treadmill test to exhaustion. Multiple regression was used to analyze the independent associations between screen time and individual cardiometabolic disease risk factors with sedentary behavior, MVPA, age, and sex used as covariates in the models. RESULTS: On average, screen time (14.8±11.6 h/week) accounted for 25% of total sedentary behavior (59.0±25.8 h/week). Screen time was positively associated with BMI (R2=0.19, β=0.35, p=0.02), waist circumference (R2=0.19, β=0.43, p<0.01), fat mass (R2=0.39, β=0.34, p=0.01), and TG (R2=0.24, β=0.43, p<0.01), and negatively associated with VO2peak (R2=0.66, β=-0.39, p<0.01). These associations were independent of total sedentary behavior, MVPA, age and sex. Screen time was not associated with blood pressure, glucose, HDL or LDL (p>0.05). CONCLUSIONS: Our findings suggest that screen time is related to individual cardiometabolic disease risk factors in young adults. Screen time accounted for 25% of sedentary time and may be an important area to target for chronic disease prevention programs in young adults. Funded by CTR-IN NIH NIGMS #1U54GM104944-01A1

Prolonged Bouts Of Sedentary Behavior Are Associated With Cardiometabolic Disease Risk Factors In Young Adults

Prolonged Bouts Of Sedentary Behavior Are Associated With Cardiometabolic Disease Risk Factors In Young Adults