Abstract We conjecture that a convex polytope is uniquely determined up to isometry by its edge-graph, edge lengths and the collection of distances of its vertices to some arbitrary interior point, across all dimensions and all combinatorial types. We conjecture even stronger that for two polytopes $P\subset {\mathbb {R}}^{d}$ and $Q\subset {\mathbb {R}}^{e}$ with the same edge-graph it is not possible that $Q$ has longer edges than $P$ while also having smaller vertex-point distances. We develop techniques to attack these questions and we verify them in three relevant special cases: $P$ and $Q$ are centrally symmetric, $Q$ is a slight perturbation of $P$, and $P$ and $Q$ are combinatorially equivalent. In the first two cases the statements stay true if we replace $Q$ by some graph embedding $q:V(G_{P})\to {\mathbb {R}}^{e}$ of the edge-graph $G_{P}$ of $P$, which can be interpreted as local resp. universal rigidity of certain tensegrity frameworks. We also establish that a polytope is uniquely determined up to affine equivalence by its edge-graph, edge lengths and the Wachspress coordinates of an arbitrary interior point. We close with a broad overview of related and subsequent questions.