Achieving high firing accuracy of tank on the move is challenging. For improving firing accuracy, better understanding launching dynamic behavior of tank firing on the move is required. This study established a rigid-flexible coupling dynamic model of tank firing on the move. Thereinto, the barrel flexibility was considered based on the FFlex body technology, and the contact-impact algorithm was used to describe the projectile-barrel interaction. With the sinusoid superposition method, a three-dimensional road surface spectrum file considering the coherence of left and right tracks was created. Based on the results obtained in simulation, this study discussed the dynamic behaviors of a tank gun system such as the barrel curvature and the influence of projectile-barrel interaction on firing accuracy of tank firing on the move, in which the factors including projectile type, driving speed and road roughness were taken into consideration. The results indicated that the barrel curvature and the muzzle vibration do not increase simply with the increase of road roughness and driving speed as common sense.