Review Of World Literature Research Articles

Breast parenchyma leiomyoma: A diagnostic challenge to treat

Breast leiomyoma is an infrequent entity and accounts for less than 1% of all breast tumors. The disease may affect both sexes with a preference for middle-aged women and its etiology still remains unclear. The nipple and subareolar area harbor the neoplasm in the majority of cases, however the intraparenchymal location, especially in older women has been noted. Histologically, this mesenchymal tumor derives from smooth muscle cells metaplasia or from myofibroblastic cells of the subareolar area. Triple assessment makes up the basic diagnostic tool. Surgical resection in macroscopic clear margins contributes not only to diagnosis but also rules out malignancy. Herein, we present our case of intramammary leiomyoma with a parallel review of world literature.

Consumerism in health care – review of Polish and world literature

Consumerism in health care – review of Polish and world literature

Instrumental Tracheal Rupture

Abstract Tracheal rupture is an urgent life-threatening complication that relates to complex and poorly understood areas of trauma surgery. The article presents a review of modern world and domestic literature on instrumental tracheal ruptures, the Relevance of early diagnosis and various treatment methods. Based on an analysis of modern literature data, the article describes the issues of conservative and surgical treatment methods, as well as an assessment of their results. The problem of the diagnostic algorithm and the choice of conservative, surgical treatment has not been solved and remains relevant. The issues of treating patients with a defect in the membranous wall of the trachea in intensive care and in need of artificial ventilation in clinical practice remain unresolved. All of the above indicates the Relevance of the study.Aim of the study To present data from domestic and foreign literature on the diagnosis and treatment of instrumental tracheal ruptures.Material and methods A review of the literature was carried out for the period from 1993 to 2024 in Russian and English, available on the databases Pubmed, Medline, UpTodate, Scopus, E-library, on topics such as post-intubation tracheal rupture, iatrogenic tracheal rupture, diagnosis and treatment of instrumental tracheal ruptures, closed tracheal injury.Results The concept of the classification system, risk factors, etiopathogenesis is outlined. Information is provided on the diagnostic significance of computed tomography and tracheobronchoscopy. Close attention is paid to the methods and choice of treatment tactics, the principles of intraoperative tactics, and the strategy of conservative treatment. A comparative assessment of treatment Results and their complications with a conservative or surgical treatment approach is given.Conclusion Thus, an analysis of domestic and foreign literature indicates that the issues of diagnosis and treatment of iatrogenic tracheal injuries remain largely unresolved. There is no generally accepted algorithm for instrumental diagnosis of tracheal ruptures. There are no uniform approaches to determining indications and contraindications for conservative and surgical treatment of tracheal injuries. There are diametrically opposed opinions regarding the choice of treatment tactics. These contradictions create significant difficulties in assessing the Results of treatment of this complex category of patients.

Final Purchasers’ Cooperation with Offerors in Online and Offline Environments

Abstract Purpose The aim of this study is to determine final purchasers’ preferred environment of cooperation with offerors. The study also sought to determine the significance of this environment in relation to (1) advantages perceived in online and offline environments as places for this cooperation and (2) the type of services final purchasers would like to co-create. Methodology The results of the world literature review indicate cognitive and research gaps in the aspects mentioned. To reduce these gaps, empirical studies were carried out. The data were subjected to quantitative analysis using statistical analysis and statistical testing. Findings The results indicated that most respondents preferred a parallel use of online and offline environments for cooperation with offerors. The preferred environment of cooperation was a feature differentiating, in a statistically significant way, each of the analysed advantages of online and offline environments as places of cooperation with offerors. The preferred environment of cooperation differentiated only responses relating to cultural services. Originality The approach presented is original. Final purchasers’ preferences concerning the environment of cooperation with offerors have been studied for the first time in the proposed context.

Tree bark is promising sorption material for extraction of hydrocarbons from aquatic environments (Review of world and domestic literature)

The literature data on the use of bark of coniferous and hardwood trees as a sorption material for the extraction of hydrocarbons from aquatic environments are summarized. It is shown that tree bark is an effective, widespread and cheap sorption material for removing oil and oil products from the water surface. It is also shown that the sorption characteristics of tree bark for oil and products of its processing can be increased by modification with various chemical reagents. It has been revealed that most of the publications are devoted to studies of the bark of coniferous trees as oil sorbents, most of all, the bark of Scotch pine (Pinus sylvestris). It is concluded that the limited number of publications on the use of hardwood bark as oil sorbents makes this line of research promising.

Primary Ewing’s sarcoma of the kidney: description of two rare clinical cases and review of world literature

Ewing’s sarcoma (ES) of the kidney is an extremely rare malignant tumor characterized by an aggressive course, and therefore the disease has an unfavorable prognosis. Due to the rare occurrence, standards for the treatment of ES of the kidney have not been developed; an integrated approach is often used in therapy. In this article, we present a description of two clinical cases of kidney damage with ES in patients aged 10 and 16 who were treated at the Research Institute of Pediatric Oncology and Hematology named after Academician of the Russian Academy of Medical Sciences L.A. Durnov at N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia. In the first case, there was a metastatic lesion of the kidney with the localization of the primary focus in the pelvic bones, in the second, primary ES of the kidney was diagnosed. Both patients had stage IVb at the time of diagnosis (TNM classification American Joint Commission on Cancer). In both patients, after induction chemotherapy, a complete therapeutic response (complete therapeutic pathomorphosis) was obtained. In an integrated approach, in addition to standard chemotherapy, surgery and radiation therapy, in both cases, high-dose chemotherapy with autologous peripheral stem cell transplantation was used, which made it possible to create favorable conditions for long-term remission in one of the patients, even despite the initial prevalence of the process.

Cutaneous lymphoproliferative disorders after COVID-19 vaccination: clinical presentation, histopathology, and outcomes

Individual reports described lymphoproliferative disorders (LPDs) after COVID-19 vaccination; however, the relationship between cases is unexamined. We aim to determine if there are cases of cutaneous LPDs associated with COVID-19 vaccination and their outcomes. We present a review of world literature, vaccine registries, and two unreported cases of LPDs after COVID-19 vaccination. Review of the medical literature, VAERS, and our two cases reveal predominance of Pfizer-BioNTech vaccine, younger patients, and males. All cases resulted in favorable outcomes. Approximately 84% of cases demonstrated CD30+ positivity in their skin biopsies, suggesting that an antigenic trigger may lead to a type IV adaptive immune response, with clonal expansion of CD30+ T-cells and subsequent oncogenic mutational hits eventuating in transient LPDs. LPDs after COVID-19 vaccination appear in the context of the same vaccines (proportionally to their global market shares), share clinical and pathological findings, and have indolent, self-limited character.

Preservation of the reproductive health of military women: global experience and realities of Ukraine

A review of world literature and Ukrainian researches on the most common requests to gynecologists among military women, on the structure of pathology and treatment methods was made. Special attention is paid to the hormonal contraception, namely combined oral contraceptives (COCs) in the usual and continuous regime (avoiding the hormone-free interval) and the levonorgestrel-releasing intrauterine systems (LNG-IUDs).Cases of global practice of using COCs in extended regimen were considered, which showed that 47.2% of 1156 women chose a prolonged regimen of COCs, the main reason for this was the desire to avoid symptoms associated with menstruation. We consider this option very positive for military women, because some studies show that military women who took COCs in a continuous regimen were almost twice as favorable to their reception as those who used them in a regular mode.The positive aspects of the LNG-IUDs use in military women are presented, as a factor in the prevention of abnormal uterine bleeding, reducing the risk of iron deficiency in case of possible blood loss, and reducing the intensity of dysmenorrhea as a negative factor in the military conditions.Ways to increase compliance between a gynecologist and a military woman are also considered, using the example of global studies, which prove that insufficient awareness of patients about the possible ways and positive effects of using COCs in extended regimen reduced patients’ commitment to choosing new regimens.Conclusions. In today’s realities, the gynecological service in our country faces a number of new problems that require a strategic approach and solution. World practice and national studies prove that stress-induced hormonal disorders in military women, such as abnormal uterine bleeding, menstrual cycle disorders, dysmenorrhea, are negative factors in combat conditions, require the attention and resolution by doctors. One of the options for solving this problem can be the appointment of COCs according to the usual and extended scheme or appointment of LNG-IUDs.

Robotization of Diagnostics of Railway Automation and Communication Systems

Purpose. The study is aimed at: gaining new knowledge about the use of electric motors in robotics; evaluation and selection of motors that are appropriate for use in robots that will move along the railway line and accurately determine the location of damage; development of a method for diagnosing railway automation and communication devices based on robotization of their maintenance and fault finding; evaluation of the use of robotics on the railways of Ukraine and the world. Methodology. The authors analyzed information on the use of electric motors in robotics, as well as the use of robots in production, which they obtained from a review of world literature, monographs, abstract, full-text and lecture databases, and scientific cooperation with leading departments of the University of Twente, the Netherlands. Findings. In the course of the study: 1) the importance of robotics, which makes it possible to replace a person in heavy and long work, was clarified; 2) a functional diagram of the robot, the manipulator drive, its components and the principle of operation was drawn up; 3) various types of drives in robots were substantiated: electric, pneumatic and hydraulic; the use of different types of motors in electric drives, their principle of operation, value and availability; 4) the prospects for the introduction of electroactive polymers and elastic nanotubes that will improve robots in the future are determined; 5) the use of robots in methods of diagnosing and detecting damage to automation and communication systems is proposed, which will facilitate and reduce maintenance time; 6) further development of scientific research and subject area in railway transport is predicted. Originality. For the first time, it is proposed to use robots to find faults in railway automation and communication lines, to introduce the latest drives that allow to improve the work of robots, reduce the number of errors in identifying line defects, and increase the accuracy and efficiency of determining the location of line damage. Practical value. Based on the research results, we can predict the further development of scientific research on robotization of diagnostics of railway automation and communication systems, the subject area of railway transport, and training in the new specialty 174 "Automation, Robotics and Computer-Integrated Technologies".This research can also be useful in organizing scientific and practical seminars, conferences, lectures, advanced training courses, etc.

Spirituality in Polish nursing and chosen tools used for its measuring – subject matter presentation based on literature review

Abstract Introduction. In times of the dehumanisation of medicine, a holistic approach to patients seems indispensable. Moreover, there is an increasing number of scientific papers on the significance of soft competencies and the non-clinical nature of care in the quality and effectiveness of therapeutic processes. The staff often neglects or ignores the elements of spiritual care in everyday practice. It results from the concern not to interfere with the patient’s personal life and from staff shortages, which entails the staff ’s heavy workload on duty. Consequently, a phenomenon known as missing nursing care was diagnosed, involving skipping some activities during everyday nursing practice in order to perform the indispensable, most essential procedures for the patient. Aim. The aim of the study was to present the importance of spiritual care in nursing and to present tools for its measurement. Method. The method is an nonsystematic review of current national and world literature. Summary. Providing spiritual care is primarily aimed at responding to patients’ needs and concerns. Such care is based on effective communication skills, through which a nurse establishes a bond and trust with the patient, and consequently, the patient is more willing to engage in therapeutic processes, so hospitalisation might be reduced significantly.

Update on Sinonasal Tract Malignancies: Advances in Diagnostic Modalities.

Sinonasal tract malignancies are rare cancers with frequent morphologic overlap. Given the similar histologic profiles seen in many of these entities, they often present a diagnostic challenge to the practicing pathologist. To provide a streamlined algorithm using histologic clues, immunohistochemical profiles, and molecular assays to aid in diagnosis of these lesions. Sources were the World Health Organization Tumor Classification, literature review, and institutional experience. Although many sinonasal tract malignancies show similar histology, distinct immunohistochemical and molecular profiles can help parse out differences, thereby facilitating diagnosis for the pathologist.

Multiple Correlation Model to Estimate Osteomyelitis in Dental Implant Candidate Patients

Introduction Osteomyelitis is an inflammatory infectious pathology that represents a public health problem due to the high morbidity associated with its high disabling potential and with a reserved short-term prognosis. The risk factors that favor the growth of a particular microorganism, in the maxilla or jaw after the placement of dental implants, include multiple general variables (age, sex, smoking and systemic diseases) as well as local variables (anatomical area, number of implants, type of osteomyelitis). The objective of this research is to perform a linear model to estimate the risk of osteomyelitis from the correlation of the multiple variables obtained from the review of the world literature. Material and Methods Descriptive, retrospective, cross-sectional study. A multiple correlation model was constructed to estimate osteomyelitis (OM) from the general variables and local variables obtained from the review of world literature in the last 10 years. Results The sample consisted of 38 patients with a minimum age of 43 years and a maximum age of 84 years and a mean of 61 years, 28 (73.6%) female patients and 10 (26.3%) males, 23 (60.5%) patients with systemic diseases and 15 (39.4%) healthy patients. Gender is related to osteomyelitis since the female sex has 13 times more risk of presenting osteomyelitis than the male gender. Age is related to osteomyelitis since at age over 60 there is 1 time more risk of osteomyelitis than those under 60 years of age. The presence of a systemic disease by itself was not statistically significant when performing the univariate logistic regression analysis, however, when performing the multivariate analysis arterial hypertension, diabetes, patients who smoke or consume immunosuppressive or immunomodulatory drugs if they are predisposed to osteomyelitis in 47% according to Cox and Snell and 64.7% according to Nagelkerke. With respect to the anatomical area, the jaw has 9 times more risk of osteomyelitis than the maxilla. Conclusion The variables selected to perform our analysis, if they can behave as risk factors for osteomyelitis. In the multivariate model, the predictors of systemic diseases are independent, even without collinearity, asthma, bronchitis and smoking are related to respiratory diseases, as well as the combination with arterial hypertension, since although the individual effect of each of the variables cannot be precisely identified, The multivariate effect translates into an increase in the estimated regression coefficient (13% more likely) to present osteomyelitis, this is known as non-perfect multicollinearity. There is no specific statistical method to estimate osteomyelitis in patients who are candidates for dental implants, however, the present multiple correlation model allows us to determine to what extent the general, local and concomitant factors reported in the literature increase the risk of presenting osteomyelitis.

A Curious Cluster of Cholesteatoma: A Family Study

Objective: We report a rare case of family clustering of cholesteatoma. Method: Case reports of three first-degree relatives in a family affected with cholesteatoma and a review of world literature on hereditary causes for cholesteatoma are presented. Results: The family consists of parents and two siblings, of whom the father and both siblings (a daughter and a son) were surgically treated for cholesteatoma. All cholesteatomas in this family cluster were acquired. Conclusion: Family clustering of acquired cholesteatoma is rare. This report indicates the interplay of hereditary factors along with environmental factors in the genesis of cholesteatoma.

Treatment of unresectable stage III NSCLC: Real world cohort study and literature review

IntroductionUntil recently, the treatment for patients with locally advanced unresectable stage III non-small cell lung cancer (NSCLC) was combined chemoradiotherapy (CRT), delivered either concurrently (cCRT) or sequentially (sCRT). There is limited data on the outcomes and safety of CRT in a real-world setting. We conducted a real-world cohort analysis of our Leuven Lung Cancer Group (LLCG) experience with CRT for unresectable stage III NSCLC, prior to the era of consolidation treatment with immunotherapy. Patients and MethodsIn this observational, real-world monocentric cohort study, a total of 163 consecutive patients were included. They were diagnosed with unresectable stage III primary NSCLC and treated with CRT between January 1st, 2011, and December 31st, 2018. Patient and tumor characteristics, treatment patterns, toxicity, and primary outcome parameters such as PFS, OS and pattern of relapse were captured. ResultsCRT was concurrent in 108 patients, sequential in 55. Overall tolerability was good, with two thirds of patients without severe adverse events such as severe febrile neutropenia, ≥ grade 2 pneumonitis, or ≥ grade 3 esophagitis. All registered adverse events were more frequent in the cCRT group compared to the sCRT group. Median PFS was 13.2 months (95% CI 10.3–16.2), median OS was 23.3 months (95% CI 18.3–28.0), with a 47.5% survival rate at 2 years, and 29.4% at five years. Conclusions: This study provides a clinically relevant benchmark on the outcomes and toxicity of concurrent and sequential chemoradiotherapy in unresectable stage III NSCLC in a real-world setting in the pre-PACIFIC era.

Chrysoprase – history and present

Abstract The authors present the history of chrysoprase discovery and the progress of knowledge about this material over the millennia, based on the extended review of world literature. Tracing the oldest archaeological artifacts from before 9,000 years, the lens of history turns on a stone that has not been properly identified mineralogically for centuries. In the 1830s, chrysoprase was finally included into the chalcedony group and its green color was associated, very correctly, with nickel compounds dispersed in its structure. After all, the most current mineralogy of chrysoprase is presented on the basis of the results of modern analytical studies. These data clearly indicate that chrysoprase is a mixture of several SiO2 polymorphs with varying degrees of structural order (opal, chalcedony, moganite, quartz). This radically changes the previous taxonomy of chrysoprase and its position in current mineralogical and petrographic systematics.

О важности междисциплинарного подхода в избирательном лечении псориаза и псориатического артрита

Psoriasis is one of the most common skin diseases. 30% of patients with psoriasis may develop psoriatic arthritis, which can lead to complex joint deformity and early disability. In this case, it is very important to have an interdisciplinary approach in the selective treatment of psoriasis and psoriatic arthritis using genetically engineered biological drugs. In our article, we present a world literature review on the use of genetically engineered biological drugs in psoriasis and psoriatic arthritis, describe a clinical case of psoriasis with psoriatic arthritis with effective basic treatment.

An asymmetric morbilliform eruption in an adult male

An asymmetric morbilliform eruption in an adult male

Critical Care Management of a Severe Acute Respiratory Distress Syndrome COVID-19 Patient With Control Cesarean Section

We share our experience of one 29-year-old female, G2 P1, with acute respiratory distress syndrome (ARDS) and at 30 weeks of pregnancy. The 30-week gravid uterus in combination with a poor ventilation-perfusion ratio creates a restrictive lung pattern that may prove to be lethal for both the mother and baby. Due to her rapid deterioration and increased hemodynamic instability we opted for controlled delivery in the operating room with an ICU physician, a Neonatologist, and an Obstetric team. At 3.27 minutes from induction, the baby was born with Apgar scores of 7 and 8. The mother was placed on a RotoProne® bed, treated with remdesivir, steroids, and was subsequently extubated seven days later. The newborn was admitted to the Neonatal Intensive Care Unit (NICU) after delivery. We have reviewed the literature and provided a concise set of recommendations based on our field experience and current world literature review. Prompt delivery in a controlled environment with multiple resuscitating teams provided expeditious treatment of both patients, maintaining oxygenation and perfusion while keeping hemodynamic stability. The controlled environment and the proximity of all teams avoided deleterious consequences to the unborn baby. This is an example where the risk of keeping the baby in the womb outweighs the premature delivery into a NICU. Both mother and baby were downgraded from their respective Intensive Care Units (ICUs) and discharged home in one month.

Повреждение дистального межберцового синдесмоза, пути улучшения результатов лечения (обзор литературы)

Introduction Treatment of patients with distal tibiofibular syndesmosis (DTFS) ruptures remains controversial. Ankle fractures accompanied by syndesmosis rupture are associated with worse outcomes. There is no diagnosis and treatment algorithm for such injuries to date. The objective was to summarize the data on diagnosis and treatment of syndesmotic injury alone and in combination with ankle fractures through world literature review. Material and methods A systematic literature search was undertaken using elibrary, PubMed, ResearchGate databases with articles dated 1990 and later. The search depth was 30 years. With preliminary information collected low-relevant articles were excluded. Meta-analysis studies, randomized controlled trials, systematic reviews, cadaveric biomechanical studies were reviewed. Results Screws and suture buttons can be used to fix DTFS, and Volkmann, Shaput and Wagstaff fractures being transosseous injuries to DTFS can be repaired with osteosynthesis. Imaging evaluation of reduction can be produced with radiography, MSCT, MRI and arthroscopy. Partial injuries to the DTFS, if timely detected, can be treated conservatively with transition to surgical stabilization if signs of instability persist. Discussion Conventional radiography has very low diagnostic value for DTFS injury. Bilateral MSCT is recommended for assessment of a syndesmotic injury and MRI of the ankle joint is practical for partial isolated injuries. Concomitant injuries of the fibular notch of the tibia are recommended to address first prior to transsyndesmotic fixation. Open reduction of displaced DTFS is accompanied by a lower risk of fibular malposition and malreduction. Suture buttons are practical for transsyndesmotic fixation. Removal of positional screws does not affect the functional result of treatment. More stable osteosynthesis would be needed for DTFS injury in neuropathy.

Застосування протоколу “MARCH” на етапі надання долікарської допомоги в умовах надзвичайних ситуацій

Introduction. According to statistics, 90% of deaths on the battlefield occur at the pre-medical stage. However, some problems, such as bleeding from the extremities, severe pneumothorax, and airway problems, can be controlled in the prehospital setting. Of all the known protocols for these conditions, the last one used in the world today is the MARCH pre-medical protocol. The aim of the study is to assess the possibility of adapting the MARCH protocol for civilians in emergencies and hostilities. Materials and methods. A review of modern world and domestic literature on the algorithms of primary home care. Results and discussion. Three basic algorithms are used to provide primary care for the wounded: 1. The “MARCH” protocol is a sequence of actions during the provision of emergency home care to the wounded both on the battlefield and at the stage of evacuation. 2. CABCDE algorithm (Western European algorithm). 3. The Wheel-Bridge Algorithm, which is used to facilitate training in first aid for the wounded based on NATO standards. It fully reproduces the sequence of NATO’s protocol in Ukrainian only. These standards are designed for physicians who provide assistance on the battlefield, and they include stages with clear objectives, but these standards can be applied to civilians at the stage of primary care in non-life-threatening conditions, ie in places where no direct combat actions. This type of care corresponds to tactical medical care. Educating citizens in the basics of tactical medicine and implementing NATOstandard pre-medical tactical care algorithms is an important aspect of hostilities that will reduce civilian mortality and awareness of military emergencies. Conclusions. The issue of insufficient training of the population in the field of first aid in case of injuries and wounds is an urgent problem and needs to be addressed by improving the practical skills of the civilian population and by developing recommendations for a first aid kit for everyday wear. The MARCH algorithm can be easily and effortlessly adapted in Ukraine and is accessible to people without medical education, and its implementation among civilians will help improve the quality of pre-medical care and reduce mortality among the population in the area of hostilities or emergencies.