Reverse Rate Research Articles

Compressive mechanical properties of styrene-butadiene rubber under medium-low strain rates: Experiments and modeling

Styrene-butadiene rubber (SBR) is widely employed as a cushioning material in engineering applications to resist impact loadings due to its excellent mechanical properties and energy absorption capacity. This paper aims to investigate the compressive mechanical properties and constitutive model of SBR under medium–low strain rates both experimentally and theoretically. Firstly, quasi-static and dynamic compression tests of SBR were carried out under the strain rate up to 220 s−1 using an electronic universal testing machine and a drop-weight machine, respectively. Subsequently, the effect of loading rate on mechanical properties, strain rate sensitivity and energy absorption capacity was examined. The results indicate that SBR exhibits visco-hyperelastic characteristics with reversible compression deformation and strain rate dependency, ie., the yield stress, flow stress and dynamic increase factor (DIF) increase approximately exponentially with increasing logarithmic strain rate. In addition, the SBR exhibits excellent energy absorption capacity during compression, especially under higher strain rates and larger strain levels. Finally, a visco-hyperelastic constitutive model was proposed by replacing the nonlinear spring with a hyperelastic element in Zhu-Wang-Tang (ZWT) viscoelastic constitutive model to describe the nonlinear mechanical behaviors in SBR, and an acceptable agreement between experimental results and model predictions were observed. The findings of this research can provide a valuable guide for designing and optimizing the impact resistance of SBR structures.

Modeling the impact of driving aggression on lane change performance Measures: Steering compensatory Behavior, lane change execution duration and crash probability

The current study aimed to investigate the influence of driving aggression on lane change behavior. Drivers belonging to three levels of aggressive driving styles (aggressive, moderately aggressive, and non-aggressive) participated in lane change experiments, and 232 lane change maneuvers were recorded. Steering behavior during lane change maneuvers was investigated using three steering performance measures, including the standard deviations of steering angle, steering reversal rates, and maximum steering swerve. Three separate generalized estimating equation models were developed to analyze the effects of aggressive driving behavior on the standard deviation of steering angle, steering reversal rates, and maximum steering swerve. A Weibull accelerated failure time model with clustered heterogeneity was developed to analyze the effect of aggressive driving behavior on lane change execution duration. Additionally, to model the crash probability during lane change, a random effects logistic regression model was developed. The findings indicate that aggressive and moderately aggressive drivers completed lane changes 59% and 38% faster, respectively, compared to non-aggressive drivers. This implies a propensity for aggressive and moderately aggressive drivers to execute lane changes more swiftly than non-aggressive drivers. Aggressive drivers increased their standard deviation of steering angle, steering reversal rates, and maximum steering swerves by 180%, 60%, and 62%, respectively, compared to non-aggressive drivers. This implies that aggressive drivers engaged in extreme steering behavior as a compensatory measure for their reckless driving in order to avoid a collision during lane change maneuvering. However, despite their vigorous compensatory steering behavior, the crash rate (number of crashes observed) increased by 5.10 and 2.83 times for aggressive and moderately aggressive drivers, respectively, compared to non-aggressive drivers. The findings have implications for developing driving assistance systems and lane change simulation models.

Predicting the reversion from mild cognitive impairment to normal cognition based on magnetic resonance imaging, clinical, and neuropsychological examinations.

Reversion from mild cognitive impairment (MCI) to normal cognition (NC) is not uncommon and indicates a better cognitive trajectory. This study aims to identify predictors of MCI reversion and develop a predicting model. A total of 391 MCI subjects (mean age=74.3years, female=61%) who had baseline data of magnetic resonance imaging, clinical, and neuropsychological measurements were followed for two years. Multivariate logistic analyses were used to identify the predictors of MCI reversion after adjusting for age and sex. A stepwise backward logistic regression model was used to construct a predictive nomogram for MCI reversion. The nomogram was validated by internal bootstrapping and in an independent cohort. In the training cohort, the 2-year reversion rate was 19.95%. Predictors associated with reversion to NC were higher education level (p=0.004), absence of APOE4 allele (p=0.001), larger brain volume (p<0.005), better neuropsychological measurements performance (p<0.001), higher glomerular filtration rate (p=0.035), and lower mean arterial pressure (p=0.060). The nomogram incorporating five predictors (education, hippocampus volume, the Alzheimer's Disease Assessment Scale-Cognitive score, the Rey Auditory Verbal Learning Test-immediate score, and mean arterial pressure) achieved good C-indexes of 0.892 (95% confidence interval [CI], 0.859-0.926) and 0.806 (95% CI, 0.709-0.902) for the training and validation cohort. Observational duration is relatively short; The predicting model warrant further validation in larger samples. This prediction model could facilitate risk stratification and early management for the MCI population.

Analysis of Misconceptions on the Factors that Affect the Reaction Rate

This study aimed to analyze the misconceptions in the chemical concept of the factors that affect reaction rates through a qualitative descriptive method. The misconceptions experienced by students were examined through analyzing journals, books, and field experiences. Furthermore, research was carried out to obtain misconceptions that were often experienced by students and the sources of those misconceptions. There were 30 misconceptions about the factors that affect the reaction rate based on the literature. Based on the results of the study, there were three misconceptions experienced by 20 students from the total number of 21 students. The misconception that most students experienced was that when the concentration of reactants increases, a reaction will take longer because there will be much more particles to collide. In addition, the rate of the same reactions was compared at different temperatures, and then the reaction with the highest temperature was defined as the rate of reaction. The next misconception was that the temperature increase in an exothermic reaction can increase the forward rate and decrease the reverse rate because the equilibrium shifts to the right. Misconceptions were caused by information from the internet, teachers teaching in schools, textbooks used by students and the everyday life experiences of students. Keywords: misconception, chemical concept, literature

Coal-based hard carbon anode for high-performance sodium ion batteries via coal-based graphene oxide as a multi-functional binder

Coal-based hard carbon for sodium ion batteries (SIBs) was successfully prepared using Shenfu bituminous coal (SFC) by one-step pyrolysis method. In the present work, we reported a novel method to fabricate carbon electrodes for SIBs from coal-based hard carbon with coal-based graphene oxide (CGO) as a multi-functional conductive binder to realize dual functional utilization of coal. As compared to traditional binder (CMC), electrodes with the CGO binder exhibits significantly increased reversible capacity and rate capability. This work provides a facile method for coal-based carbon materials used in SIBs.

Management of hepatorenal syndrome and associated outcomes: a systematic review

BackgroundHepatorenal syndrome (HRS), a multiorgan condition of acute kidney injury, is seen in advanced liver disease. This study aims to evaluate the current treatment for HRS.MethodsThe authors searched PubMed, Scopus...

Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago

BackgroundLiterature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA.MethodsThis is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up.Results564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections.ConclusionsAfter 100 years since the first Hartmann’s procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment’s choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception.

Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance

Antibiotics are considered one of the most important contributions to clinical medicine in the last century. Due to the use and overuse of these drugs, there have been increasing frequencies of infections with resistant pathogens. One form of resistance, heteroresistance, is particularly problematic; pathogens appear sensitive to a drug by common susceptibility tests. However, upon exposure to the antibiotic, resistance rapidly ascends, and treatment fails. To quantitatively explore the processes contributing to the emergence and ascent of resistance during treatment and the waning of resistance following cessation of treatment, we develop two distinct mathematical and computer-simulation models of heteroresistance. In our analysis of the properties of these models, we consider the factors that determine the response to antibiotic-mediated selection. In one model, heteroresistance is progressive, with each resistant state sequentially generating a higher resistance level. In the other model, heteroresistance is non-progressive, with a susceptible population directly generating populations with different resistance levels. The conditions where resistance will ascend in the progressive model are narrower than those of the non-progressive model. The rates of reversion from the resistant to the sensitive states are critically dependent on the transition rates and the fitness cost of resistance. Our results demonstrate that the standard test used to identify heteroresistance is insufficient. The predictions of our models are consistent with empirical results. Our results demand a reevaluation of the definition and criteria employed to identify heteroresistance. We recommend that the definition of heteroresistance should include a consideration of the rate of return to susceptibility.

Synthesis of a fluorescent probe for rhodamine B and determination of Zn2+ content in pharmaceutical zinc gluconate

The intermediate LBXJ was prepared by Rhodamine B, hydrazine hydrate and HCl, and then the probe Y2ST was prepared by LBXJ, chromone 3-formaldehyde and absolute ethanol. NMR characterized the structures of the intermediate and probe, IR and MS. Compared the fluorescence selectivity of ions after the system was determined and tested the response time, pH value, cation interference, reversibility, linearity, detection limit, accuracy, coordination ratio, and recovery rate of the samples. The detection limit of Y2ST was 0.7×10-6 mol/L, and the detection rate of Zn2+ in zinc gluconate was 96.1% at 5×10-6 mol/L--5×10-5 mol/L. It can be used for the content determination of Zn2+.

Ni‐Single Atoms Modification Enabled Kinetics Enhanced and Ultra‐Stable Hard Carbon Anode for Sodium‐Ion Batteries

AbstractHard carbon with randomly oriented interlayers is the most promising candidate for the anode of commercial sodium‐ion batteries (SIBs). Nevertheless, its sluggish sodium storage kinetics and unsatisfactory cycling stability are bottlenecks to its implementation. Herein, a metal‐single atom modification strategy is proposed to construct a Ni‐single atoms modified N, P co‐doped hard carbon (Ni‐NPC) with a Ni content of ≈5.65 wt%. As an anode for SIBs, Ni‐NPC exhibits far superior initial Coulombic efficiency, reversible specific capacity, rate capability, and cycling stability to N, P co‐doped hard carbon. Combining in situ EIS and ex‐situ XPS,this study reveals that Ni‐single atoms modulate the composition of the solid electrolyte interface layer, thereby improving the cycling stability of Ni‐NPC. Theoretical calculation and kinetics analysis suggest that Ni‐single atoms are the promoters of the diffusion of Na+. Furthermore, with the aid of systematic in situ characterizations, the structural evolution of Ni‐NPC at different sodium storage stages is identified. This work proposes a potential strategy for simultaneously improving the sodium storage kinetics and cycling stability of hard carbon anodes, and elucidates the improvement mechanism of this strategy.

(O-22) EPIDEMIOLOGICAL PROFILE OF PATINTS UNDERGOING VASECTOMY REVERSATION AT PEDRO ERNESTO UNIVERSITY HOSPITAL

Abstract Introduction Review of vasectomy reversal cases operated in the Urology department of HUPE. From January 2012 to January 2023, 61 vasectomy reversals were performed at Hospital Universitário Pedro Ernesto to correct obstructive azoospermia, with patients' ages ranging from 33 to 70 years and vasectomy time ranging from 2 to 15 years. Patients, except those who did not return for followup despite instructions, were followed up on an outpatient basis with sperm analysis 30 days after surgery and then every six months until the end of follow-up. Among the 42 patients who maintained outpatient follow-up (68% of the total), our casuistry presents 31 reverted patients (73% of this group), that is, with viable spermatozoa present in the spermogram. Of these, 4 patients managed to generate a pregnancy (12% of the reverted ones), with children still alive to date, 5 are no longer trying for personal reasons (16% of the reverted ones), and 22 are still trying (70% of the reverted ones). 11 patients were unsuccessful in reversal (26% of those who followed up). 19 patients lost outpatient follow-up (32% of the total). Objectives To observe the epidemiology of operated patients, analyzing the effectiveness of the procedure and understanding the fate of operated patients. Methods Work without control group, case series. Results High reversal rate, but with a low pregnancy rate and significant rate of loss to outpatient followup. Conclusion Through the analytical observation of epidemiology, outline conducts mainly regarding the outpatient follow-up of patients, given the high rate of loss to follow-up. Financing No conflict.

In Situ Defect Engineering in Carbon by Atomic Self-Activation to Boost the Accessible Low-Voltage Insertion for Advanced Potassium-Ion Full-Cells.

Enhancing the low-potential capacity of anode materials is significant in boosting the operating voltage of full-cells and constructing high energy-density energy storage devices. Graphitic carbons exhibit outstanding low-potential potassium storage performance, but show a low K+ diffusion kinetics. Herein, in&nbsp;situ defect engineering in graphitic nanocarbon is achieved by an atomic self-activation strategy to boost the accessible low-voltage insertion. Graphitic carbon layers grow on nanoscale-nickel to form the graphitic nanosphere with short-range ordered microcrystalline due to nickel graphitization catalyst. Meanwhile, the widely distributed K+ in the precursor induces the activation of surrounding carbon atoms to in situ generate carbon vacancies as channels. The graphite microcrystals with defect channels realize reversible K+ intercalation at low-potential and accessible ion diffusion kinetics, contributing to high reversible capacity (209mAhg-1 at 0.05Ag-1 under 0.8V) and rate capacity (103.2mAhg-1 at 1Ag-1). The full-cell with Prussian blue cathode and graphitic nanocarbon anode maintains an obvious working platform at ca. 3.0V. This work provides a strategy for the in situ design of carbon anode materials and gives insights into the potassium storage mechanism at low-potential for high-performance full-cells.

QuantiFERON-TB reversion in children and adolescents with tuberculosis.

We analyzed 136 children with tuberculosis disease or infection and a positive QuantiFERON-TB (QFT) assay, followed-up for a median of 21 months (0.4-11years). QFT reversed in 16.9% of cases, with significant decreases in TB1 (-1.72 vs. -0.03 IU/ml, p=0.001) and TB2 (-1.65 vs. -0.43 IU/ml, p=0.005) levels compared to non-reverters. We found a higher QFT reversion rate among children under 5 years (25.0% vs 11.9%, p=0.042), and those with TST induration <15mm (29% vs 13.3%, p=0.055). Our data reveal that, although QFT test remained positive in the majority of children, reversion occurred in 16% of cases in a progressive and stable pattern. Younger age and reduced TST induration were associated with QFT reversion.

Labile assembly of a tardigrade protein induces biostasis.

Tardigrades are microscopic animals that survive desiccation by inducing biostasis. To survive drying tardigrades rely on intrinsically disordered CAHS proteins, which also function to prevent perturbations induced by drying in vitro and in heterologous systems. CAHS proteins have been shown to form gels both in vitro and in vivo, which has been speculated to be linked to their protective capacity. However, the sequence features and mechanisms underlying gel formation and the necessity of gelation for protection have not been demonstrated. Here we report a mechanism of fibrillization and gelation for CAHS D similar to that of intermediate filament assembly. We show that in vitro, gelation restricts molecular motion, immobilizing and protecting labile material from the harmful effects of drying. In vivo, we observe that CAHS D forms fibrillar networks during osmotic stress. Fibrillar networking of CAHS D improves survival of osmotically shocked cells. We observe two emergent properties associated with fibrillization; (i) prevention of cell volume change and (ii) reduction of metabolic activity during osmotic shock. We find that there is no significant correlation between maintenance of cell volume and survival, while there is a significant correlation between reduced metabolism and survival. Importantly, CAHS D's fibrillar network formation is reversible and metabolic rates return to control levels after CAHS fibers are resolved. This work provides insights into how tardigrades induce reversible biostasis through the self-assembly of labile CAHS gels.

Length of hysterotomy for fetal spina bifida repair is associated with prematurity risk.

To investigate whether prenatal repair of spina bifida aperta through mini-hysterotomy results in less prematurity, as compared to standard hysterotomy, when adjusting for known prematurity risks. We performed a bi-centric, propensity score matched, controlled study, that is, adjusting for factors earlier reported to result in premature delivery or membrane rupture, in consecutive women having prenatal repair either through stapled hysterotomy or sutured mini-hysterotomy (≤3.5cm). Matches were pairwise compared and cox-regression analysis was performed to define the hazard ratio of delivery <37weeks. Of 346 meeting the MOMS-criteria, 78 comparable pairs were available for matched-controlled analysis. Mini-hysterotomy patients were younger and had a higher BMI. Mini-hysterotomy was associated with a 1.67-lower risk of delivery <37weeks (hazard ratio: 0.60; 95% CI: 0.42-0.85; p=0.004) and 1.72 for delivery <34+6weeks (hazard ratio: 0.58; 95% CI: 0.34-0.97; p=0.037). The rate of intact uterine scar at birth (mini-hysterotomy: 98.7% vs. hysterotomy: 90.4%; p=0.070), the rate of reversal of hindbrain herniation within 1week after surgery (88.9% vs. 97.4%; p=0.180) and the rate of cerebrospinal fluid leakage (0% vs. 2.7%; p=0.50) were comparable. Prenatal spina bidifa repair through mini-hysterotomy was associated with a later gestational age at delivery and a comparable intact uterus rate without apparent compromise in neuroprotection.

Structural engineering of MoSe2 via interfacial effect and phosphorus doping incorporation for high energy density sodium ion storage

Sodium-ion batteries (SIBs) are gaining increasing attention for the development of electrode materials due to their potential to alleviate the safety concerns and resource scarcity associated with lithium-ion batteries (LIBs). Based on this, the present work, built upon the electrospinning preparation of hollow carbon nanofibers (HCNFs), facilitated the in-situ growth of MoSe2 nanosheets on their surface. Subsequently, an in-situ phosphorization treatment was applied, resulting in phosphorus-doped MoSe2 (P-MoSe2)@HCNFs. The dual-channel inner layer of HCNFs in this structure promotes ion transport and directly interfaces with MoSe2, leading to abundant interfacial effects. The outer layer of MoSe2 serves as the primary redox-active unit for sodium ions, retaining numerous active sites. P doping further optimizes the overall electronic structure of the material. P-MoSe2@HCNFs serves as the anode material in SIBs, demonstrating exceptional reversible specific capacity and rate capabilities. It achieves a remarkable 479.17 mAh g−1 over 500 cycles at 1 A g−1 and 397.01 mAh g−1 over 950 cycles at 10 A g−1, showcasing its outstanding performance. These values significantly surpass those of MoSe2@HCNFs and pure MoSe2, validating the pronounced advantages of the structure we have constructed. Leveraging the outstanding kinetic performance of P-MoSe2@HCNFs, when assembled with Na3V2(PO4)3 as the cathode, the full cell exhibits remarkable sodium storage capability. It achieves a high energy density of up to 194.75 Wh kg−1, providing a feasible solution for the application of transition metal selenides in sodium-ion battery systems.

Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP.

Fentanyl and fentanyl analogs (F/FA) have become increasingly common adulterants in counterfeit prescription pills and illicit street drug mixtures due to their ease of synthesis and exceedingly high potency. The ongoing epidemic of fatal overdoses fueled by F/FA continues to highlight the need for longer-acting therapies than naloxone (NLX), the current gold-standard for reversing opioid overdoses, which shows limited efficacy to prevent renarcotization associated with F/FA toxicity. A novel opioid reversal agent based on covalent naloxone nanoparticles (cNLX-NP) has been shown to blunt fentanyl-induced respiratory depression out to 48 hr, demonstrating its potential therapeutic utility. The purpose of this study was to characterize how rapidly cNLX-NP reverses fentanyl-induced respiratory effects as well as the duration of its protective effects. Sprague Dawley male rats (n=6/group) were tested on an oximeter for baseline percent arterial oxygen saturation (%SaO2) challenged with 0.1 mg/kg SC fentanyl and 15min later given 10 mg/kg IM doses of NLX, nalmefene (NLMF), or cNLX-NP and continuously monitored via oximetry for 10 minutes. One week later the experiment was repeated using a 1:1 mixture of NLX:cNLX-NP as the reversal agent in the rats that previously received NLX alone. While both NLX and NLMF rapidly reversed %SaO2 to baseline within 1min, rats that received cNLX-NP did not return to >90% SaO2 levels until 9min after administration. Similarly, heart and breath rates returned to baseline within 1min of treatment with NLX and NLMF but did not return to baseline until 10 minutes after cNLX-NP administration. In contrast, NLX:cNLX-NP reversed all fentanyl-induced respiratory depressive effects within one minute. While cNLX-NP alone may not sufficiently reverse F/FA overdose in a timely manner, mixing free NLX with cNLX-NP can provide a mechanism to both rapidly reverse fentanyl-related effects and maintain extended protection against synthetic opioid toxicity. These data support further development of cNLX-NP as a fast-acting and long-lasting antidote to treat F/FA-induced respiratory depression and overdose, and potentially prevent renarcotization in humans.

Pengaruh Suku Bunga BI Rate dan BI 7 Day Reverse Repo Rate terhadap Inflasi di Indonesia dengan Metode Vector Autoregression (VAR)

This research aims to investigate and analyze the influence of the BI Rate and BI 7 Day Reverse Rate (BI 7 DRRR) on Inflation in Indonesia. The study utilizes secondary data covering BI Rate, BI 7 DRRR and Inflation for the period 2011-2022, obtained from the official website of Bank Indonesia. The research employs a quantitative desciptive approach, employing Vector Autoregression (VAR) as the analytical tool. The findings indicate that the BI Rate has a positive and significant impact on inflation in Indonesia, whereas BI 7 DRRR exhibits a negative and insignificant influence on inflation in Indonesia at a 5% significance level

Modification of the Ni-Rich Layered Cathode Material by Hf Addition: Synergistic Microstructural Engineering and Surface Stabilization.

The rapid decline of the reversible capacity originating from microcracks and surface structural degradation during cycling is still a serious obstacle to the practical utilization of Ni-rich LiNixCoyAl1-x-yO2 (x ≥ 0.8) cathode materials. In this research, a feasible Hf-doping method is proposed to improve the electrochemical performance of LiNi0.9Co0.08Al0.02O2 (NCA90) through microstructural optimization and structural enhancement. The addition of Hf refines the primary particles of NCA90 and develops them into a short rod shape, making them densely arranged along the radial direction, which increases the secondary particle toughness and reduces their internal porosity. Moreover, Hf-doping stabilizes the layered structure and suppresses the side reactions through the introduction of robust Hf-O bonding. Multiple advantages of Hf-doping allowed significant improvement of the cycling stability of LiNi0.895Co0.08Al0.02Hf0.005O2 (NCA90-Hf0.5), with a reversible capacity retention rate of 95.3% after 100 cycles at 1 C, as compared with only 82.0% for the pristine NCA90. The proposed synergetic strategy combining microstructural engineering and crystal structure enhancement can effectively resolve the inherent capacity fading of Ni-rich layered cathodes, promoting their practical application for next-generation lithium-ion batteries.

Prevalence and Molecular Characterization of Vancomycin Variable Enterococcus faecium Isolated From Clinical Specimens.

Vancomycin variable Enterococcus (VVE) bacteria are phenotypically susceptible to vancomycin, but they harbor the vanA gene. We aimed to ascertain the prevalence of VVE among clinically isolated vancomycin-susceptible Enterococcus faecium (VSE) isolates, as well as elucidate the molecular characteristics of the vanA gene cluster within these isolates. Notably, we investigated the prevalence and structure of the vanA gene cluster of VVE. Between June 2021 and May 2022, we collected consecutive, non-duplicated vancomycin-susceptible Enterococcus faecium (VSE) samples. Real-time PCR was performed to detect the presence of vanA, vanB, and vanC. Overlapping PCR with sequencing and whole-genome sequencing were performed for structural analysis. Sequence types (STs) were determined by multilocus sequence typing. Exposure testing was performed to assess the ability of the isolates to acquire vancomycin resistance. Among 282 VSE isolates tested, 20 isolates (7.1%) were VVE. Among them, 17 isolates had partial deletions in the IS1216 or IS1542 sequences in vanS (N=10), vanR (N=5), or vanH (N=2). All VVE isolates belonged to the CC17 complex and comprised five STs, namely ST17 (40.0%), ST1421 (25.0%), ST80 (25.0%), ST787 (5.0%), and ST981 (5.0%). Most isolates were related to three hospital-associated clones (ST17, ST1421, and ST80). After vancomycin exposure, 18 of the 20 VVEs acquired vancomycin resistance. Considering the high reversion rate, detecting VVE by screening VSE for vanA is critical for appropriate treatment and infection control.