The increasing use of photovoltaics (PVs) in distribution systems owing to the low-carbon policy has given rise to the need for various technological changes. In particular, the operation of on-load tap changers (OLTCs) has attracted attention. In traditional distribution systems, the OLTC operates via a line-drop compensator (LDC), which focuses on the load to solve the low-voltage problem; however, the problem of over-voltage caused by PVs persists. Currently, a method for operating an OLTC using the measured voltage is being researched; however, solving the voltage problem for several feeders connected to a main transformer (MT) is not viable. Therefore, this study proposes an OLTC operation method to address the feeder with the largest voltage problem depending on the direction of power flow. The proposed method selects a point where the OLTC operates using the difference between the measured and reference voltages. Setting the reference voltage can solve the problem that occurs due to the direction of power flow. Finally, the effectiveness of the proposed method is verified via case studies. Based on the results, we can conclude that the proposed method effectively solves the voltage problem, and an increase in hosting capacity can be expected.