Restricted Parameter Research Articles

Primary Cell Wall Modifying Proteins Regulate Wall Mechanics to Steer Plant Morphogenesis.

Plant morphogenesis involves multiple biochemical and physical processes inside the cell wall. With the continuous progress in biomechanics field, extensive studies have elucidated that mechanical forces may be the most direct physical signals that control the morphology of cells and organs. The extensibility of the cell wall is the main restrictive parameter of cell expansion. The control of cell wall mechanical properties largely determines plant cell morphogenesis. Here, we summarize how cell wall modifying proteins modulate the mechanical properties of cell walls and consequently influence plant morphogenesis.

Experimental Study Wind Turbine Performance of Straight-Savonius and Ice-Wind Type on the Similar proportion Aspect Ratio

The Performance of wind turbines at low speed can be improved by Ice-Wind model, particularly in self-starting conditions. Compared to a traditional wind turbine with two blades of the similar area and material, Ice-Wind can increase efficiency by 19%. Research on the Savonius turbine, particularly the Ice-Wind turbine, is challenging. It is because it has many restrictive parameters, such as the height, diameter, and area of the turbine blades. The Ice-Wind turbine shape is obtained by cutting a Savonius turbine. This process led to research on Ice-Wind turbines only under the similar parameters. The aspect ratio of a Savonius turbine has a significant effect on the speed, mechanical power and static-torque produced by the wind turbine. The research was done on Savonius and Ice-Wind turbines with the similar aspect ratio. The results show that the speed, power factor and efficiency of the Savonius turbine are higher than those of Ice-Wind. However, Savonius produces a smaller static-torque coefficient value than Ice-Wind. The results of this research contrast with other studies comparing Savonius and Ice-Wind turbines. In other researches, Savonius and Ice-Wind turbines have the similar area but different aspect ratios.

Design and implementation of nZEB buildings in Poland. Building certification.

The article will discuss the design and construction aspects of nearly zero-energy buildings (nZEB) in Poland. It is the newest building standard introduced by the Directive on the energy performance of buildings 2010/31/EU. The directive made the implementation of nZEB buildings compulsory in European countries. The article will present analyzes of the energy performance of nZEB buildings, in accordance with Polish legal requirements, and discuss the possibility of achieving this standard in terms of economic efficiency. An important issue is also the certification of newly designed buildings, allowing the promotion of buildings with more restrictive parameters than the minimum energy efficiency requirements specified for nZEB buildings. In the article, the authors will present the developed methodology for certifying buildings in Poland, based on the requirements related to energy efficiency, and on in situ testing of buildings. The article will also present examples of building certification in Poland.

Sodium and/or fluid restriction and nutritional parameters of adult patients with heart failure: A systematic review and meta-analysis of randomized controlled trial.

Heart failure (HF) is a clinical syndrome resulting from the structural and/or functional impairment of blood supply to tissues. Congestion and edema associated with water retention are the main symptoms presented by patients. Fluid (FR) and sodium restriction are non-pharmacological measures indicated in clinical practice to mitigate this symptom, despite their low evidence level. Assessing the impact of sodium and/or fluid restriction on nutritional parameters of adult patients with HF, based on systematic review with meta-analysis. The study was conducted in June 2020, on the following databases: EMBASE, PubMed/MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science. Citations were also collected in the gray literature such as thesis banks and preprints. Randomized clinical trials conducted with patients in the age group 18 years, or older, who were hospitalized or under outpatient/clinical follow-up, and who were subjected to intervention based on fluid and/or sodium restriction in comparison to the control, were herein selected. Although FR-based diets are effective in reducing liquid intake, they increase individuals' thirst sensation and body weight in comparison to non-FR diets. The association between this intervention and sodium restriction is also effective in reducing liquid intake as sodium intake decreases. However, the association of the most severe (<2000mg/day) and moderate (2000-2400mg/day) sodium restrictions with FR has reduced energy intake, although without evidence of weight change - only the most severe sodium restriction was capable of keeping individuals' thirst sensation. In addition, moderate sodium restrictions (2300 to 3000mg/day) in association with FR were capable of decreasing urinary sodium excretion. On the other hand, prescriptions of severe or moderate sodium restriction (<2,400mg/d) alone have reduced individuals' body weight and BMI, although they did not change their caloric intake. However, severe sodium restriction (<2,000mg) has led to higher body weight than the low-sodium diet (2000 to 2,4000mg/day). Sodium restriction may not be an effective strategy because it adversely affects individuals' weight, a fact that suggests increased congestion. Weight-based FR is supported to bethe best way to individualize this non-pharmacological treatment and it does not appear to affect nutritional parameters capable of putting patients with HF at higher malnutrition risk.

Prediction of Electromagnetic Characteristics in Stator End Parts of a Turbo-Generator Based on MLP and SVR

In order to study the multiple restricted factors and parameters of the eddy current loss of generator end structures, both the multi-layer perceptron (MLP) and support vector regression (SVR) are used to study and predict the mechanism of the synergistic effect of metal shield conductivity, relative permeability of clamping plates and structural characteristics of eddy current losses. Based on the eddy current losses of generator end structures under different metal shielding thicknesses and electromagnetic properties, the calculation accuracy of the MLP and SVR is compared. The prediction method gives an effective means for the complex design of the end region of the generator, which reduces the effort of the designers. It also promotes the design efficiency of the electrical generator.

Review of diffusion-weighted imaging and dynamic contrast-enhanced MRI for multiple myeloma and its precursors (monoclonal gammopathy of undetermined significance and smouldering myeloma).

The last decades, increasing research has been conducted on dynamic contrast-enhanced and diffusion-weighted MRI techniques in multiple myeloma and its precursors. Apart from anatomical sequences which are prone to interpretation errors due to anatomical variants, other pathologies and subjective evaluation of signal intensities, dynamic contrast-enhanced and diffusion-weighted MRI provide additional information on microenvironmental changes in bone marrow and are helpful in the diagnosis, staging and follow-up of plasma cell dyscrasias. Diffusion-weighted imaging provides information on diffusion (restriction) of water molecules in bone marrow and in malignant infiltration. Qualitative evaluation by visually assessing images with different diffusion sensitising gradients and quantitative evaluation of the apparent diffusion coefficient are studied extensively. Dynamic contrast-enhanced imaging provides information on bone marrow vascularisation, perfusion, capillary resistance, vascular permeability and interstitial space, which are systematically altered in different disease stages and can be evaluated in a qualitative and a (semi-)quantitative manner. Both diffusion restriction and abnormal dynamic contrast-enhanced MRI parameters are early biomarkers of malignancy or disease progression in focal lesions or in regions with diffuse abnormal signal intensities. The added value for both techniques lies in better detection and/or characterisation of abnormal bone marrow otherwise missed or misdiagnosed on anatomical MRI sequences. Increased detection rates of focal lesions or diffuse bone marrow infiltration upstage patients to higher disease stages, provide earlier access to therapy and slower disease progression and allow closer monitoring of high-risk patients. Despite promising results, variations in imaging protocols, scanner types and post-processing methods are large, thus hampering universal applicability and reproducibility of quantitative imaging parameters. The myeloma response assessment and diagnosis system and the international myeloma working group provide a systematic multicentre approach on imaging and propose which parameters to use in multiple myeloma and its precursors in an attempt to overcome the pitfalls of dynamic contrast-enhanced and diffusion-weighted imaging.Single sentence summary statementDiffusion-weighted imaging and dynamic contrast-enhanced MRI provide important additional information to standard anatomical MRI techniques for diagnosis, staging and follow-up of patients with plasma cell dyscrasias, although some precautions should be taken on standardisation of imaging protocols to improve reproducibility and application in multiple centres.

Machine-learned phase diagrams of generalized Kitaev honeycomb magnets

We use a recently developed interpretable and unsupervised machine-learning method, the tensorial kernel support vector machine (TK-SVM), to investigate the low-temperature classical phase diagram of a generalized Heisenberg-Kitaev-$\Gamma$ ($J$-$K$-$\Gamma$) model on a honeycomb lattice. Aside from reproducing phases reported by previous quantum and classical studies, our machine finds a hitherto missed nested zigzag-stripy order and establishes the robustness of a recently identified modulated $S_3 \times Z_3$ phase, which emerges through the competition between the Kitaev and $\Gamma$ spin liquids, against Heisenberg interactions. The results imply that, in the restricted parameter space spanned by the three primary exchange interactions -- $J$, $K$, and $\Gamma$, the representative Kitaev material $\alpha$-${\rm RuCl}_3$ lies close to the boundaries of several phases, including a simple ferromagnet, the unconventional $S_3 \times Z_3$ and nested zigzag-stripy magnets. A zigzag order is stabilized by a finite $\Gamma^{\prime}$ and/or $J_3$ term, whereas the four magnetic orders may compete in particular if $\Gamma^{\prime}$ is anti-ferromagnetic.

Bounding the mim‐width of hereditary graph classes

AbstractA large number of ‐hard graph problems are solvable in time when parameterized by some width parameter. Hence, when solving problems on special graph classes, it is helpful to know if the graph class under consideration has bounded width. In this paper we consider maximum‐induced matching width (mim‐width), a particularly general width parameter that has a number of algorithmic applications whenever a decomposition is “quickly computable” for the graph class under consideration. We start by extending the toolkit for proving (un)boundedness of mim‐width of graph classes. By combining our new techniques with known ones we then initiate a systematic study into bounding mim‐width from the perspective of hereditary graph classes, and make a comparison with clique‐width, a more restrictive width parameter that has been well studied. We prove that for a given graph , the class of ‐free graphs has bounded mim‐width if and only if it has bounded clique‐width. We show that the same is not true for ‐free graphs. We identify several general classes of ‐free graphs having unbounded clique‐width, but bounded mim‐width; moreover, we show that a branch decomposition of constant mim‐width can be found in polynomial time for these classes. Hence, these results have algorithmic implications: when the input is restricted to such a class of ‐free graphs, many problems become polynomial‐time solvable, including classical problems, such as ‐ Colouring and Independent Set, domination‐type problems known as Locally Checkable Vertex Subset and Vertex Partitioning (LC‐VSVP) problems, and distance versions of LC‐VSVP problems, to name just a few. We also prove a number of new results showing that, for certain and , the class of ‐free graphs has unbounded mim‐width. Boundedness of clique‐width implies boundedness of mim‐width. By combining our results with the known bounded cases for clique‐width, we present summary theorems of the current state of the art for the boundedness of mim‐width for ‐free graphs. In particular, we classify the mim‐width of ‐free graphs for all pairs with . When and are connected graphs, we classify all pairs except for one remaining infinite family and a few isolated cases.

Singular value decomposition‐based iterative robust cubature Kalman filtering and its application for integrated global positioning system/strapdown inertial navigation system navigation

The issue of non-linear robust state estimation in the integration of a strapdown inertial navigation system and global positioning system is addressed in this study. Based on the cubature Kalman filtering frame, a non-linear robust filter called a robust cubature Kalman filter (RCKF) was introduced to address the outliers and the inaccurate model. It has been found that the determination of an optimal restriction parameter is crucial for maintaining the robustness and accuracy of the non-linear robust filter. Unfortunately, the value of this restriction parameter is always determined by experience. In this study, an iterative strategy was proposed to adaptively attain the optimal restriction parameter without much previous experience. To improve the computational stability of the iterative non-linear robust filter, a singular value decomposition strategy was adopted simultaneously. Two case studies indicate that the iterative RCKF can achieve greater robustness and accuracy using the methodology discussed in this study.

Predicting the potential habitat of Russian-Olive (Elaeagnus angustifolia) in urban landscapes

Russian-olive (Elaeagnus angustifolia) is a species native to southern Europe and central and eastern Asia. This species plays an important role in urban landscape design because of its rapid growth, resistance in harsh climates and tolerance to human-caused pressure. Understanding its potential dispersal and restricting parameters are the first steps toward the sustainable use of this species. Here, we used Species Distribution Models to predict the potential distribution of Russian-olive in Iran climate and estimate the possible limiting factors for its spread. Our results highlighted the importance of environmental variables including climatic factors, soil, and lithology in the distribution of this species throughout the country. According to these results, suitable habitats for Russian-olive are located in the north of Iran along the Alborz and Koppeh-Dagh mountain ranges. Therefore, the suitable habitats for this species are limited to only nine percent of the country. A habitat suitability map can be used to evaluate future developments in urban areas and predict the dispersal range of Russian-olive in Iran. Our results show that Russian-olive can be used to create new green spaces in urban climates in the northern regions of Iran.

PO-1099 To plan and deliver adjuvant breast radiotherapy over 1 week: 1-week breast workflow implementation

Purpose or Objective To limit hospital visits and transportation of the patients with early breast cancer (BC) especially during the covid-19 pandemic, we aimed to implement a workflow of treatment to prepare and deliver adjuvant breast radiotherapy (RT) within 1 week. Materials and Methods Based on the Fast Forward RT schedule of 5 fractions of 5.2 Gy over 5 days for adjuvant BC, we designed a workflow to perform BC RT over 1 week from the first RT consultation to the end of treatment (figure 1). Patients were seen in consultation on Monday morning. The planning CT was carried out immediately after the consultation. A deep inspiration breath-hold technique was systematically offered to all patients. Automatic delineation using an artificial Intelligence (AI) based model with ART-PlanTM software was first corrected by a junior radiation oncologist (RO) then, independently by a senior RO. As 3D conformal RT failed to achieve dose constraints of the fast forward trial in many cases (due to breast hotspots), we developed a restricted IMRT (rIMRT) technique based on 2 tangential beams (internal and external) using inverse planning restricted optimization parameters to improve the dose homogeneity. Treatment planning was semi-automated by scripting the creation and optimization steps of rIMRT plans. After validation of the reliability of rIMRT treatment delivery by patient-specific quality assurance (PSQA) with gamma index evaluation on 20 patients, we decided to abandon systematic PSQAs. In-vivo dosimetry was validated by end-to-end controls and performed for each patient during the first fraction on Monday afternoon. Daily repositioning was controlled by portal images of the largest segment of each beam. Structured baseline, end of treatment and follow up evaluation forms were used to prospectively collect toxicities and oncological outcomes at each consultation. Patient agreement for data collection and analysis was prospectively obtained. $Φg Results From February 2021 to March 2021, the 1-week breast procedure was proposed to up to 3 patients/week, >65 years, in complete resection after conservative surgery, with pT1-T3 N0 BC, without tumor bed boost or regional lymph nodes irradiation. Six out of seven patients (85.7%) accepted the 1-week breast procedure. All procedures were successfully conducted over 5 days with complete patient and RT team satisfaction. A followup of acute toxicities by online consultation on day 10, structured evaluation forms and management decision trees has been implemented for these patients. No grade >2 acute toxicities (CTACE V4.0) have been reported so far. Conclusion The successful implementation of this comprehensive 1-week breast workflow with AI based delineation and semi-automated rIMRT without PSQA demonstrates the practical feasibility of the whole procedure over 5 days reducing drastically the coming-and-going to the hospital and the overall RT management time per patient. Our work opens the way for further development of comprehensive compact workflows in various settings.

Fitness dependence preserves selection for recombination across diverse mixed mating strategies

Meiotic recombination and the factors affecting its rate and fate in nature have inspired many studies in theoretical evolutionary biology. Classical theoretical models have inferred that recombination can be favored under a rather restricted parameter range. Thus, the ubiquity of recombination in nature remains an open question. However, these models assumed constant recombination with an equal rate across all individuals within the population, whereas empirical evidence suggests that recombination may display certain sensitivity to ecological stressors and/or genotype fitness. Models assuming condition-dependent recombination show that such a strategy can often be favored over constant recombination. Moreover, in our recent model with panmictic populations subjected to purifying selection, fitness-dependent recombination was quite often favored even when any constant recombination was rejected. By using numerical modeling, we test whether such a ‘recombination-rescuing potential’ of fitness dependence holds also beyond panmixia, given the recognized effect of mating strategy on the evolution of recombination. We show that deviations from panmixia generally increase the recombination-rescuing potential of fitness dependence, with the strongest effect under intermediate selfing or high clonality. We find that under partial clonality, the evolutionary advantage of fitness-dependent recombination is determined mostly by selection against heterozygotes and additive-by-additive epistasis, while under partial selfing, additive-by-dominance epistasis is also a driver.

Polymorphism of CYP3A4 isoenzyme gene in patients with chronic rheumatic heart disease

AIM: This study aimed to identify the associations of CYP3A4 isoenzyme gene polymorphism with the parameters of echocardiography (EchoCG), spirometry, and endothelial function of patients with chronic rheumatic heart disease (CRHD).&#x0D; MATERIALS AND METHODS: A total of 128 patients with CRHD (15.6% men and 84.4% women) were examined. A392A, A392G, and G392G polymorphic markers were genotyped through polymerase chain reaction (PCR) with an SNP-EXPRESS electrophoretic scheme (NPF Litekh, Russia) to detect results after DNA was isolated from leukocytes in venous blood. EchoCG was implemented on an Affinity 50 apparatus (Philips, the Netherlands), endothelial function was assessed with an AngioScan01 apparatus (AngioScan-Electronics, Russia), and respiratory function was examined using a SpiroLab II spirometer (MIR Medical, Italy).&#x0D; RESULTS: The distance in a 6 min walk test did not show any significant differences among the groups: A392A 327.47 6.71 m, A392G 303.63 26.19 m, G392G 338.87 20.12 m (p=0.505). The area of the mitral opening was as follows: A392A 1.74 (1.67; 1.81) cm2, A392G 1.68 (1.45; 1.92) cm2, and G392G 1.65 (1.67; 1.81) cm2 (p = 0.214). As for the EchoCG parameters, the group of G392G homozygotes had the lowest linear dimensions of the left ventricle (the end diastolic dimension 4.83 (4.72; 4.95) cm, the end systolic dimension 2.97 (2.79; 3.14) cm, the right ventricle (2.45 [2.32; 2.58] cm), of the right atrium (4.09 [3.56; 4.62] cm), and the criteria of left ventricular hypertrophy (thickness of the interventricular septum 0.88 [0.81; 0.95] cm, and the posterior wall 0.88 (0.81; 0.95 cm). No statistically significant differences were found in the occlusion index amplitude among the groups, that is, single nucleotide replacements of CYP3A4 had no influence on the system of low-resistance arteries. Conversely, the values of the phase shift between channels (reflecting the condition of large arteries) significantly differed. The G392G polymorphism showed the worst parameters, and minimal changes were observed in the A392A group. Contour analysis demonstrated the highest augmentation index values in the G392G group, reflecting the maximal stiffness of vessels. The CYP3A4 polymorphism had no effect on the parameters of respiratory function in the studied cohort of patients. Spirometry revealed that the obstructive and restrictive parameters were not significant although homozygotes demonstrated the highest forced vital capacity of the lungs (76.5% [71.1% and 82.0%]) and forced expiratory volume for 1 s (84.6% [79.0% and 90.3%]). The maximal parameter of the vital capacity of the lungs in homozygotes for A392A (85.6% [82.3% and 88.8%]).&#x0D; CONCLUSION: Patients with CRHD homozygous for G392G had the minimum parameters of hypertrophy and dimensions of the left ventricular cavity. They also had the lowest values for the cavities of the right heart. CYP3A4 polymorphism had no effect on the parameters of respiratory function in the studied patients with CRHD.

Window mean survival time.

We propose a class of alternative estimates and tests to restricted mean survival time (RMST) which improves power in numerous survival scenarios while maintaining a level of interpretability. The industry standards for interpretable hypothesis tests in survival analysis, RMST and logrank tests (LRTs), can suffer from low power in cases where the proportional hazards assumption fails. In particular, when late differences occur between survival curves, our proposed estimate and class of tests, window mean survival time (WMST), outperforms both RMST and LRT without sacrificing interpretability, unlike weighted rank tests (WRTs). WMST has the added advantage of maintaining high power when the proportional hazards assumption is met, while WRTs do not. With testing methods often being chosen in advance of data collection, WMST can ensure adequate power without distributional assumptions and is robust to the choice of its restriction parameters. Functions for performing WMST analysis are provided in the survWM2 package in R.

Nonlinear control of infection spread based on a deterministic SEIR model.

In this study, a mathematical model (SEIR model) with a restriction parameter is used to explore the dynamic of the COVID-19 pandemic. This work presents a nonlinear and robust control algorithm based on variable structure control (VSC) to control the transmission of coronavirus disease (COVID-19). The VSC algorithm is a control gain switching technique in which is necessary to define a switching surface. Three switching surfaces are proposed based on rules that depend on: (i) exposed and infected population, (ii) susceptible and infected population, and (iii) susceptible and total population. In case (iii) a model-based state estimator is presented based on the extended Kalman filter (EKF) and the estimator is used in combination with the VSC. Numerical results demonstrate that the proposed control strategies have the ability to flatten the infection curve. In addition, the simulations show that the success of lowering and flattening the epidemic peak is strongly dependent on the chosen switching surfaces. A comparison between the VSC and sliding mode control (SMC) is presented showing that the VSC control can provide better performance taking into account two aspects: time duration of pandemic and the flattened curve peak with respect to SMC.

Lump and rogue wave solutions to a (2+1)-dimensional Boussinesq type equation

In this paper, we study a (2+1)-dimensional Boussinesq type equation. By applying the Hirota direct method, lump and line rogue wave solutions are presented with the aid of symbolic computations. The solutions are expressed in terms of a set of restricted parameters with necessary and sufficient conditions that guarantee their existence. An interesting result is that when the parameters meet the rank requirement, we have lump solutions, otherwise, we may get line rogue waves.

Comparison of cosmic string and superstring models to NANOGrav 12.5-year results

We compare the spectrum of the stochastic gravitational wave background produced in several models of cosmic strings with the common-spectrum process recently reported by NANOGrav. We discuss theoretical uncertainties in computing such a background, and show that despite such uncertainties, cosmic strings remain a good explanation for the potential signal, but the consequences for cosmic string parameters depend on the model. Superstrings could also explain the signal, but only in a restricted parameter space where their network behavior is effectively identical to that of ordinary cosmic strings.

DEVELOPMENT AND ANALYSIS OF 2D FLIGHT PLANNING SEARCH ENGINE CONSIDERING FUSION OF SWIM DATA

Flight planning is one of the essential factors of the airline operation. The selection of routes will determine the economic value of the flight. However, some conditions may prevent the flight to use the most optimum route due to airspace restriction or weather condition. The research aims to develop a search engine program that uses dynamic flight parameters that considers fusion of System Wide Information Management (SWIM) data including weather data and NOTAM to produce the most optimum route in 2D flight planning. The Dijkstra’s pathfinding is implemented in Python programming language to produce the flight plan. The navigation data used is enroute airway in Indonesian FIR regions. The scenario used is a flight from Jakarta to Makassar with duration of 2 hours flight with considering the effect of restricted airspace and weather blockage during in-flight. The study also uses the optimum route produced by the algorithm to be compared with the possible alternate routes to define how optimum the route is. Adding a restricted airspace parameter will result in a new optimum flight plan that able avoids the airspace and the most minimum distance. The effect of external wind parameter could influence the optimum route which may vary depends on the speed of the wind.

Microbolometer parameters optimization for high-performance focal plane array

For high-performance microbolometric focal plane array, a pair of mutually restricted microbolometer performance parameters are analyzed and discussed. The main parameters optimization contradiction is between the microbolometric infrared signal to noise ratio and signal bandwidth, and these two performance characteristics parameters are decisive to the target-temperature resolution and imaging speed of the microbolometric focal plane array respectively. The microbolometric output signal to noise ratio of unit-power infrared signal and signal bandwidth are theoretically derived from the thermal balance equation of the typical microbolometer, and some vital factors to cause the optimization contradiction between them are revealed through theoretical analyses and numerical calculations. The microbolometer parameters optimization method based on these theoretical analyses and numerical calculations is pointed out, which can be guidable to design, fabricate and operate microbolometric focal plane arrays with high-performance characteristic parameters such as high temperature resolution and infrared image speed.

Stability analysis of the spin evolution fixed points in inspiraling compact binaries with black hole, neutron star, gravastar, or boson star components

Based on the secular spin evolution of black holes, neutron stars, gravastars, or boson stars in precessing compact binaries on eccentric orbit, we identify the aligned and more generic coplanar configurations of the spins and orbital angular momentum as fix points. Through a dynamical system analysis, we investigate their linear stability as function of the mass quadrupole parameter. Marginal stability holds for the binary configurations with both spins antialigned to the orbital angular momentum, for both spins aligned to the orbital angular momentum (with the exception of certain quadrupolar parameter ranges of neutron stars and boson stars), and for the extremal mass ratio. For equal masses, the configurations of one of the spins aligned and the other antialigned is stable for gravastar binaries, for neutron star binaries in the high quadrupolar parameter range, and for boson star binaries. For some unequal mass gravastar binaries, black hole binaries or neutron star binaries, a transition from stability to instability can occur during the inspiral, when one of the spins is aligned, while the other is antialigned to the orbital angular momentum. We discover a transitional instability regime during the inspiral of certain gravastar, neutron star, or boson star binaries with opposing spins. For coplanar configurations we find instabilities only for the gravastar - gravastar, boson star - boson star and black hole - boson star binaries. For a given spin configuration, marginal stability strongly depends on the value of the quadrupolar parameters. The stability region is larger for neutron star binaries than for black hole binaries, while the mixed systems have a restricted stability parameter region.