Background Clinicians often face issues in restoring teeth with extensive root canals using various restorative methods. For clinical success these methods of restoration must be evaluated.Methods A randomized controlled trial was conducted on sixty extracted intact maxillary premolars. The prmolars were collected and equally divided into six groups. Except for G1 all the other groups were treated endodontically G2 MOD preparation without restoration G3 MOD preparation with resin composite restoration G4 MOD preparation with resin composite restoration amp restored with porcelain fused metal crown G5 MOD preparation restored with glass fiber horizontal post and resin composite and G6 MOD preparation restored with Polyethylene fiber mesh. The specimens were loaded in a micro universal testing machine until the fracture occurred. Failure loads were then statistically analyzed. The mode of failure was determined by visual inspection.Results Composite resin restorations reinforced with a fiberglass horizontal post and polyethylene mesh significantly increased fracture resistance of endodontically treated premolar teeth with MOD cavity. Conclusion Fiberglass horizontal post can be used as an alternative for post endodontic restoration in endodontically treated teeth with MOD cavities.