Respiratory Health Status Research Articles

Stress, Depression, Coping Strategy and Respiratory Health Status of Traffic Police at Anand District, Gujarat, India

Introduction: There is lot of stress and stress associated mental illness among the traffic police fraternity. Many environmental factors are responsible for this development. Measurement of the stress levels and implementation of coping strategies are very important to maintain the health of the traffic police. Aim: To assess the level of stress, depression, coping strategy and respiratory health status of traffic police at Anand district, Gujarat, India. Materials and Methods: This cross-sectional descriptive study including 100 participants was conducted by the Department of Mental Health Nursing, Manikaka Topawala Institute of Nursing, Charotar University of Science and Technology, Anand District, Gujarat, India from December 2019 to February 2020. Validated tool Job Stress Scale, standardised tool beck depression inventory, coping strategy scale were used to assess the level of stress, depression and coping strategy respectively. Spirometer was used to assess respiratory function. Analysis was done using Statistical Package for the Social Sciences (SPSS) statistical software version 20.0 and Spirometry Longitudinal Data Analysis (SPIROLA) software version 3.0.3. Results: The study reveals that majority (69%) of the traffic police were facing extreme stress, 11% of traffic police were suffering from mild mood disorder, 73% were having adequate coping skills, 88% were non smokers and 97% traffic police were not using any substances, 65% demonstrated expiratory Forced Vital Capacity (FVC) of 2.6%-3.5%, 66% demonstrated 2.6%-3.5% Forced Expiratory Volume in 1 second (FEV1), 76% experienced 96-100 FEV1/FVC ratio1, 53% experienced 6%-8% peak expiratory flow. Pulmonary function test found to be normal however, it is declined in smokers comparative to non smokers. Conclusion: The study concludes that stress and depression were observed in traffic police which they were managing with adaptive coping strategy. However, pulmonary function is found normal in comparing to predictive value, necessary precautions need to be taken by Traffic Police Department by offering protective device like mask to decrease the respiratory health issues.

A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome: two-year outcomes

Objective To assess at 24 months corrected age (CA) the neurological, respiratory, and general health status of children born prematurely from 27+0 to 33+6 weeks’ gestation who were treated in a first-in-human study with a new fully synthetic surfactant (CHF5633) enriched with SP-B and SP-C proteins. Outcome measures Children were assessed using Bayley Scales of Infant Development (BSID), with a score below normal defined as BSID-II Mental Development Index score <70, or BSID-III cognitive composite score <85. In addition, a health status questionnaire was used to check for functional disability including respiratory problems and related treatments, sensory and neurodevelopment assessments, communication skills as well as the number of hospitalizations. Results 35 of 39 survivors had a neurodevelopmental assessment, 24 infants being evaluated by Bayley’s Scales and 11 by health status questionnaires only. 23 children had scores within normal limits and one had BSID-III <85. The remaining 11 were judged clinically to have normal development. Health status questionnaires detected only issues that would normally be expected in preterm-born children. Conclusions This assessment offers reassurance that treatment with CHF5633 surfactant was not associated with adverse neurodevelopmental, respiratory, or health outcomes by two years corrected age.

RESPIRATORY SYMPTOMS AND PULMONARY FUNCTION IMPAIRMENT AMONG TEXTILE INDUSTRY WORKERS IN ALEXANDRIA GOVERNORATE

Introduction: Cotton dust inhalation is responsible for the major respiratory symptoms and disease among textile workers. In spite of the seriousness of exposure to cotton dust, little concern has been given to the problem in Egypt and other developing countries.Aim of the work: Assessment of the respiratory health status of textile industry workers.Subjects: All male textile workers exposed to cotton dust in a textile factory located in Alexandria Governorate(n=184). A comparison population consisted of 180 workers not exposed to cotton dust or any other hazards that might affect the respiratory system were selected from same factory. Methods: A cross sectional comparative design was adopted for this research. All workers were subjected to a self-structured interviewing questionnaire to obtain personal and occupational history, British Medical Research Council questionnaire (BMRC) on respiratory symptoms and smoking habit, byssinosis diagnosis questionnaire based on schilling criteria and pulmonary function measurement. Results: The prevalence of chronic cough, chronic phlegm production and chronic bronchitis were significantly higher among exposed workers the mean values of lung function indices reflecting large airways function as forced expiratory volume in one second (FEV1) and peak expiratory flow rate (PEFR) were significantly lower in exposed workers compared to unexposed workers.Conclusions: Occupational exposure to cotton dust was associated with increased prevalence of respiratory symptoms and obstructive pattern in pulmonary function test.

Changes in children's respiratory morbidity and residential exposure factors over 25 years in Chongqing, China.

BackgroundRespiratory morbidity and mortality during childhood remains a major challenge for global health. Due to the rapid economic development in Chongqing, we expect substantial temporal changes in respiratory health status and environmental risk factors in children. By leveraging a historical dataset, this study aims to assess the changes in prevalence of respiratory symptoms and diseases, residential exposure factors, and their associations in school-age children over a period of 25 years.MethodsThis study involved two cross-sectional surveys conducted in Chongqing with a 25-year interval (2017 vs. 1993). Purpose sampling was used to conduct questionnaire surveys on school-age children in both surveys. Information collected include children’s respiratory health outcomes, family residential exposures, demographic information, and parental respiratory disease history. The changes of residential exposures as well as demographics were determined by chi-square test. Odds ratios were calculated to compare the prevalence of children’s respiratory symptoms and diseases between the two periods. Associations between children’s respiratory outcomes and exposure indicators were assessed using multivariate logistic regressions.ResultsThe majority of residential exposure indicators improved in 2017, including sleep in shared room, cooking with coal, poor kitchen ventilation, cooking frequency, and parental smoking. Compared to the 1993 study, the adjusted risk for children’s wheezing was lower (OR: 0.38, 95% CI: 0.29, 0.49), but the risk for bronchitis was higher (OR: 1.89, 95% CI: 1.54, 2.31) in the 2017 study. Poor kitchen ventilation and parental smoking were linked to an increased risk of children’s wheezing (OR: 1.39, 95% CI: 1.02, 1.90) and bronchitis (OR: 1.51, 95% CI: 1.02, 2.21), respectively, while heating in winter was linked to an increased risk of phlegm (OR: 1.40, 95% CI: 1.03, 1.90) and wheezing (OR: 1.47, 95% CI: 1.07, 2.01) in the 1993 study. However, these residential exposure factors were no longer associated with the children’s respiratory diseases in the 2017 study.ConclusionsOur study found improvement of residential exposures in Chongqing, a decline of prevalence of children’s wheezing but an increase of that of bronchitis from 1993 to 2017. Poor kitchen ventilation, heating in winter, and parental smoking were significant risk factors in the 1993 survey but, with significantly reduced prevalence in 2017, were not significantly associated with children’s respiratory morbidity in the latter survey.

Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status

Morphine is used as palliative treatment of chronic breathlessness in patients with advanced chronic obstructive pulmonary disease (COPD). Evidence on respiratory adverse effects and health status is scarce and conflicting. To assess the effects of regular, low-dose, oral sustained-release morphine on disease-specific health status (COPD Assessment Test; CAT), respiratory outcomes, and breathlessness in patients with COPD. Participants were randomly assigned to 10 mg of regular, oral sustained-release morphine or placebo twice daily for 4 weeks, with the possibility to increase to 3 times daily after 1 or 2 weeks. The Morphine for Treatment of Dyspnea in Patients With COPD (MORDYC) study was a randomized, double-blind, and placebo-controlled study of a 4-week intervention. Patients were enrolled between November 1, 2016, and January 24, 2019. Participants were recruited in a pulmonary rehabilitation center and 2 general hospitals after completion of a pulmonary rehabilitation program. Outpatients with COPD and moderate to very severe chronic breathlessness (modified Medical Research Council [mMRC] breathlessness grades 2-4) despite optimal pharmacological and nonpharmacological treatment were included. A total of 1380 patients were screened, 916 were ineligible, and 340 declined to participate. Primary outcomes were CAT score (higher scores represent worse health status) and arterial partial pressure of carbon dioxide (Paco2). Secondary outcome was breathlessness in the previous 24 hours (numeric rating scale). Data were analyzed by intention to treat. Subgroup analyses in participants with mMRC grades 3 to 4 were performed. A total of 111 of 124 included participants were analyzed (mean [SD] age, 65.4 [8.0] years; 60 men [54%]). Difference in CAT score was 2.18 points lower in the morphine group (95% CI, -4.14 to -0.22 points; P = .03). Difference in Paco2 was 1.19 mm Hg higher in the morphine group (95% CI, -2.70 to 5.07 mm Hg; P = .55). Breathlessness remained unchanged. Worst breathlessness improved in participants with mMRC grades 3 to 4 (1.33 points lower in the morphine group; 95% CI, -2.50 to -0.16 points; P = .03). Five participants of 54 in the morphine group (9%) and 1 participant of 57 in the placebo group (2%) withdrew because of adverse effects. No morphine-related hospital admissions or deaths occurred. In this randomized clinical trial, regular, low-dose, oral sustained-release morphine for 4 weeks improved disease-specific health status in patients with COPD without affecting Paco2 or causing serious adverse effects. The worst breathlessness improved in participants with mMRC grades 3 to 4. A larger randomized clinical trial with longer follow-up in patients with mMRC grades 3 to 4 is warranted. ClinicalTrials.gov Identifier: NCT02429050.

Balneotherapy and hydrotherapy in chronic respiratory disease.

Chronic respiratory diseases (CRD) belong to major noncommunicable diseases (NCD) targeted by World Health Organization (WHO) NCD Action Plan and United Nations (UN) Sustainable Development Goal (STG) 3.4 to achieve 30% decline of mortality by the year 2030. Strong evidence is now available in the literature for therapeutic aquatic exercise interventions in improving health status of chronic obstructive pulmonary diseases (COPD) patients. However, gym-based exercises can be difficult for patients with COPD who are mainly elderly and often have co-morbidities—such as severe arthritis and obesity—which may impair their ability to exercise at an adequate intensity. Besides improving respiratory function and health status in COPD, exercise in water helps overcoming patient’s fears and promote socialization, contrasting the risk of depression, which is a major condition often associated with long term COPD condition. Susceptibility to respiratory infections plays a role in exacerbations of COPD. Sulphur-rich water inhalations improve muco-ciliary clearance, reduce inflammatory cytokines production and inflammatory mucosal infiltration, reduce elastase secretion by neutrophils, preserving elastic properties of pulmonary interstitium and thus facilitating expectoration. Repeated cold water stimulations in COPD also reduce frequency of infections. Finally, sauna bathing reduces the risk of pneumonia. On the other side, hydrotherapy/balneotherapy also help obesity control, which is one of the most difficult NCD risk factors to modify and consequently is an important component of the WHO preventive strategy to achieve STG 3.4. Along with high prevalence and mortality, CRD cause increasing pharmaceutical and hospital costs. In this perspective, Health Resort Medicine should not be ignored as a resource in the WHO NCD strategy and Universal Health Coverage, providing a multi-stakeholder platform (including the network of health resorts and their facilities) able to give a real help to the achievement of UN goal STG 3.4 by the year 2030.

CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial

BackgroundOral CXC chemokine receptor 2 (CXCR2) antagonists have been shown to inhibit neutrophil migration and activation in the lung in preclinical and human models of neutrophilic airway inflammation. A previous study with danirixin, a reversible CXCR2 antagonist, demonstrated a trend for improved respiratory symptoms and health status in patients with COPD.MethodsThis 26-week, randomised, double-blind, placebo-controlled phase IIb study enrolled symptomatic patients with mild-to-moderate COPD at risk for exacerbations. Patients received danirixin 5, 10, 25, 35 or 50 mg twice daily or placebo in addition to standard of care. Primary end-points were the dose response of danirixin compared with placebo on the incidence and severity of respiratory symptoms (Evaluating Respiratory Symptoms in COPD [E-RS:COPD] scores) and safety. Secondary end-points included the incidence of moderate-severe exacerbations, health status (COPD Assessment test, CAT) and health-related quality of life HRQoL (St. George Respiratory Questionnaire-COPD, SGRQ-C).ResultsA total of 614 participants were randomized to treatment. There were no improvements in E-RS:COPD, CAT or SGRQ-C scores in participants treated with any dose of danirixin compared to placebo; a larger than expected placebo effect was observed. There was an increased incidence of exacerbation in the danirixin-treated groups and an increased number of pneumonias in participants treated with danirixin 50 mg.ConclusionsThe robust placebo and study effects prohibited any conclusions on the efficacy of danirixin. However, the absence of a clear efficacy benefit and the observed increase in exacerbations in danirixin-treated groups suggests an unfavorable benefit-risk profile in patients with COPD.Trial registrationThis study was registered with clinicaltrials.gov, NCT03034967.

Industrial Air Pollution and Respiratory Health Status among Residents in an Industrial Area in Central Italy.

The area of Civitavecchia (Lazio region, Central Italy) has been a reason of concern in the past because of environmental air contamination. The aim of this study was to evaluate the association between air pollution from different sources and respiratory symptoms and lung function in the population. A sample of 1177 residents underwent medical examination and lung function tests. Information on individual characteristics, histories of exposure and medical history were collected through a validated questionnaire. Long-term exposure to industrial, harbour, biomass combustion emissions (PM10) and urban traffic (NOx) at residential address was assessed using a Lagrangian dispersion model. The associations between exposure and wheezing and dyspnea were assessed using logistic regression models, while modified Poisson regression models were used to evaluate cough with phlegm. Relationships between exposure and lung function were analysed using linear mixed-effects models and cross-correlation. PM10 emissions from the harbour were associated with lower lung function parameters (FEV1: β = –0.12, 95% CI –0.21 –0.03; p = 0.02; FEV1/FVC: β = –1.67, (–3.10 –0.23); p = 0.02. This association was observed also in healthy subjects, but not in females. We found, even if at low exposure level, an effect of environmental PM10 exposure from harbour on lung function.

Allergic and Respiratory Symptoms in Employees of Indoor Cannabis Grow Facilities.

While little is known about the occupational hazards associated with Cannabis cultivation, both historical research in the hemp industry and preliminary data from modern grow houses, suggest that Cannabis workers may be at increased risk of respiratory and allergic diseases. We sought to investigate the association between workplace exposures and health symptoms in an indoor Cannabis grow facility in Washington State, USA. We performed a cross-sectional study with all consenting employees in an indoor Cannabis grow facility in Seattle, WA using a questionnaire. The questionnaire gathered data on respiratory, ocular, nasal, and dermal symptoms. A subset of employees with work-related symptoms underwent repeated cross-shift and cross-week measurement of spirometry, fractional exhaled nitrogen oxide (FeNO), and skin prick testing for Cannabis sensitization. Exposure to Cannabis dust was classified based on self-described tasks, expert opinion, and exposure monitoring of particulate matter. Multivariable logistic regression was undertaken to examine associations between exposure to Cannabis dust (classified as low, medium, and high) and health symptoms. Linear mixed effects models examined the relationship between cross-shift and cross-week changes in spirometry and FeNO. Ninety-seven percent (97%) of the employees (n = 31) surveyed were recreational cannabis users, with 81% (n = 25) smoking cannabis multiple times per day. Twenty-two (71%) employees reported one or more work-related symptoms: 65% respiratory, 39% ocular, 32% nasal, and 26% dermal symptoms. There was a trend toward increased likelihood of work-related symptoms with increasing exposure to Cannabis dust, although none of these results were statistically significant. Of the 10 employees with work-aggravated symptoms, 5 had borderline-high or high FeNO, 7 had abnormal spirometry, and 5 had evidence of Cannabis sensitization on skin prick testing. FeNO increased by 3.78 ppb (95% confidence interval 0.68-6.88 ppb) across the work-week and there was a trend toward cross-week and cross-shift reduced airflow. We found a high prevalence of work-related allergic- and particularly respiratory symptoms in the employees of one indoor Cannabis grow facility in Washington State. A high proportion of employees with work-aggravated symptoms had findings consistent with probable work-related asthma based on high FeNO, airflow obstruction on spirometry, and Cannabis sensitization on skin prick testing. However, due to the high incidence of recreational cannabis use among these workers, the relative influence of occupational versus recreational exposure to Cannabis dust on the respiratory health and sensitization status of these workers could not be resolved in this study.

Chronic Obstructive Pulmonary Disease Prevalence and Associated Factors in a Setting of Well-Controlled HIV, A Cross-Sectional Study

In Sub-Saharan Africa, COPD remains prevalent but its association with HIV is not well characterized especially in rural settings. We assessed for COPD prevalence, associated factors and lung function profile among HIV-infected individuals attending ART clinics in rural Nakaseke district of Uganda. We enrolled HIV-positive participants from four HIV treatment centers in rural Uganda. Participants underwent spirometry testing following standard guidelines. We defined COPD as a post-bronchodilator FEV1/FVC ratio less than the fifth percentile of the NHANES III African-American reference. We assessed for factors associated with COPD and lung function profiles using multivariable logistic and linear regression analyses. We analyzed data from 722 HIV-positive participants (mean age 48.0 years, 59.7% women). Over 90% of participants were on ART for a median duration of 4 years (IQR 2–7 years), with a median viral load of 0 copies/mL (IQR 0–0 copies/mL), current and baseline CD4 + T cell count of 478 cells/mm3 (IQR 346–663 cells/mm3) and 335 cells/mm3 (IQR 187–523 cells/mm3) respectively. The prevalence of COPD was 6.22%. COPD was associated with worse respiratory symptoms and health status. History of pulmonary tuberculosis was strongly associated with COPD (adjusted OR = 4.92, 95% CI 1.71 to 14.15, p = 0.003) and reduced lung function. Use of ART, CD4+T cell count and viral load were not associated with COPD or reduced lung function. In conclusion, we report a COPD prevalence of 6.22% in HIV-infected individuals in rural Uganda. Pulmonary tuberculosis remains the strongest predictor of COPD risk and reduced lung function in well-controlled HIV.

Decreased handgrip strength can predict lung function impairment in male workers: a cross sectional study

BackgroundSpirometry is useful for evaluating respiratory health status and predicting health-related outcomes. As spirometry requires skilled technician and takes time, it is useful to find simple way for predicting lung function impairment. The aim of this study was to investigate which tests could predict lung function impairment among workers.MethodsThis prospective study included workers of manufacturing industry who underwent health check-ups in 2017. Subjects underwent the chronic obstructive pulmonary disease (COPD) assessment test (CAT), spirometry, and physical fitness assessments, including handgrip strength (HGS). Lung function impairment was defined as a decline in any of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), or a FEV1/FVC ratio less than the lower limit of normal (LLN).ResultsComplete data on 475 workers (366 men, 50.4% ever smokers) were available. Lung function impairment was observed in 99 subjects (64 men). Men with lung function impairment had significantly higher rate of ever-smoking, passive smoking at home in childhood, high CAT scores, and decreased HGS, compared with those without. On multivariate analyses, ever-smoking (odds ratio [OR], 2.50; 95% confidence intervals [CI], 1.25–4.97), passive smoking at home in childhood (OR, 2.71; 95% CI, 1.16–6.32), CAT scores (OR, 1.06; 95% CI, 1.01–1.12), and HGS (OR, 0.73; 95% CI, 0.57–0.92) were independently associated with lung function impairment in men.ConclusionsEver-smoking, passive smoking at home in childhood, high CAT scores, and decreased HGS are significantly associated with lung function impairment in men.Trial registrationRegistration number: UMIN000028011. Date of registration: July 1, 2017.

Association between indoor environment and common cold among children aged 7–9 years in five typical cities in China

The common cold is an acute, self-limited viral infection of the upper respiratory tract, it is a heterogeneous group of diseases caused by numerous viruses that belong to several different families. A total of 292 households with children aged 7–9 years from Harbin, Xi’an, Ningbo, Nanning, and Shenzhen, China were investigated and 877 air samples from both bedrooms and living rooms in study area were tested to reveal indoor air quality level in 2017. The mean indoor temperature, relative humidity, CO, CO 2 , NO 2 , formaldehyde, total count of colonies, and total count of fungi levels were 21.00 ​± ​4.05 ​°C, 54.66 ​± ​16.28%, 0.85±+2.99 mg/m 3 , 0.08 ​± ​0.06%, 0.03 ​± ​0.02 ​mg/m 3 , 0.03 ​± ​0.02 ​mg/m 3 , 173.14 ​± ​4.28 ​cfu/m 3 , and 241.21 ​± ​4.20 ​cfu/m 3 , respectively. Of the 292 children, 1.72% had >5 common colds in the past year, 12.04% 3–5 per year, and rest <3 per year. The average prevalence of the common cold in five cities was 1.68 times per year with an average duration of 5.62 days. The main symptoms of a common cold in children are cough and expectoration, which are significantly influenced by indoor relative humidity, formaldehyde, and total count of fungi. The total count of fungi as well as relative humidity are also significantly correlated with the duration of children common cold. And significant correlation was found between indoor temperature and the prevalence of a common cold. This study systematically analyzed influence of indoor environment, including physical variables, chemical variables, and biological variables, on common cold in children and identified essential indoor risk factors in China. • The average prevalence of the common cold in five typical cities in China was 1.68 times per year with an average duration of 5.62 days. •The main symptoms of a common cold in children are cough and expectoration. •The main symptoms, duration, and prevalence of a common cold in children are significantly influenced by indoor temperature, relative humidity, formaldehyde, and total count of fungi. •The socioeconomic status (SES) of the family affects indoor environment as well as respiratory health status of the child to some extent.

Respiratory health disorders associated with occupational exposure to bioaerosols among workers in poultry breeding farms.

Working in poultry farms revealed the exposure to chemical and biological emissions (bioaerosols) that might be related to respiratory diseases in the workers and an increased loss in lung function. The current study aimed to determine the respiratory health status among poultry farm workers and to monitor the biological and the environmental conditions at ten poultry farms in Egypt. It reported that the total dust, ammonia (NH3), and carbon dioxide (CO2) concentrations in the studied poultry farms did not exceed the permissible exposure limits except farm V where NH3 was slightly exceeded the recommended levels. 35.7% of the poultry farm workers had positive nose and throat culture (bacterial and fungal). The poultry farm workers had higher prevalence of cough, wheeze, and shortness of breath with lower mean values of spirometric measurements than the controls (P < 0.05). Also, the positive culture poultry farm workers had significantly higher respiratory manifestations and lower spirometry values than negative culture ones (P < 0.05). Therefore, intervention programs for reducing the exposure are amendatory point for the health and safety of poultry farm workers.

Association Between Obesity and Cardiovascular Outcomes: Updated Evidence from Meta-analysis Studies.

The prevalence of obesity and cardiovascular disease (CVD) has been increasing worldwide. Studies examining the association between adiposity and CVD outcomes have produced conflicting findings. The interplay between obesity and CVD outcomes in the general population and in specific subpopulations is complex and requires further elucidation. We report updated evidence on the association between obesity and CVD events through a review of meta-analysis studies. This review identified that obesity or high body mass index (BMI) was associated with an increased risk of CVD events, including mortality, in the general population and that cardiac respiratory fitness (CRF) and metabolic health status appear to stratify the risk of CVD outcomes. In patients with diabetes, hypertension, or coronary artery disease, mortality displayed a U-shaped association with BMI. This U-shaped association may result from the effect of unintentional weight loss or medication use. By contrast, patients with other severe heart diseases or undergoing cardiac surgery displayed a reverse J-shaped association suggesting the highest mortality associated with low BMI. In these conditions, a prolonged intensive medication use might have attenuated the risk of mortality associated with high BMI. For the general population, a large body of evidence points to the importance of obesity prevention and maintenance of a healthy weight. However, for those with diagnosed cardiovascular diseases or diabetes, the relationship between BMI and cardiovascular outcomes is more complex and varies with the type of disease. More studies are needed to define how heterogeneity in the longitudinal changes in BMI affects mortality, especially in patients with severe heart diseases or going under cardiac surgery, in order to target subgroups for tailored interventions. Interventions for managing body weight, in conjunction with improving CRF and metabolic health status and avoiding unintentional weight loss, should be used to improve CVD outcomes.

EXPOSURE TO VEHICULAR POLLUTION AND RESPIRATORY IMPAIRMENT IN TRAFFIC POLICE MEN OF PUNE CITY A REVIEW

The phenomenon called pollution is an inescapable consequence of the presence of man and his activities. In Unani Medicine, the concept of Air pollution is known as Fizai Aaloodgi. The Air is said to be Alooda [polluted] when it is mixed with Dukhan [smoke] or Gubar [dusty haze]. This Dukhan or Gubar is originated from different sources. In urban areas mobile or vehicular pollution is predominant and significantly contributes to air quality problems. Road traffic produce volatile organic compounds, suspended particular matters, which makes adverse health effects on the exposed population. The aim of this study was respiratory impairment in traffic policemen by vehicular pollution and the effect on their respiratory health status using various objectives test and a questionnaire. After the analysis of collection of date it is found that there is a significant difference between Group I (Traffic Police) and Group II non traffic police. In these criteria related to respiratory treatment such as respiratory rate recurrent headache, attack of Asthma, attack of cough, running nose and watery eyes.

Evaluation of respiratory health among refuse management and sanitation board workers in Kano metropolis

Context: Kano State Refuse Management and Sanitation board workers are constantly exposed to bioaerosol inhalation, including toxins and biotoxins that are been released from the waste. Aims: The aim of this study is to evaluate and determine the respiratory health status of Workers. Methodology: The study was a cross-sectional survey with 129 participants recruited using a convenience sampling technique. Forced vital capacity, forced expiratory volume in 1 s and St. George questionnaire were used to collect data and the result was analysed using descriptive statistics of frequencies, percentages and graphs, while the differences and relationships were obtained using one-way ANOVA and Spearman rank correlation co-efficient, respectively. Results: The mean age of the participants was 34.2 years. Up to 75.2% of the participants were male, whereas 24.8% were female. Up to 40% of participants did not have any respiratory symptoms, 35% had mild symptoms, 14% had moderate symptoms and 11% had severe respiratory symptoms. The symptoms include dyspnea, coughing, excessive mucus secretion and breathlessness. Respiratory symptoms was positively related to the length of exposure (P = 0.029). There was no significant difference in respiratory symptoms between waste collectors, sweepers and drivers. Furthermore, no relationship was found between the age of the workers and respiratory symptom (P = 0.056). Significant difference (P = 0.003) was observed between gender of the participants and respiratory health. Conclusions: Waste disposal work has significant impact on respiratory health. The provision of health education for safety and proper use of personal protection is necessary to reduce the impact of pollutant on respiratory health.

Associations of Ambient Air Pollutant Concentrations With Respiratory Symptoms and Perceived Health Status in Japanese Adults With and Without Chronic Respiratory Diseases: A Panel Study.

ObjectivesIn recent years, transboundary air pollution from mainland East Asia has led to growing concerns about air pollution in Japan. Air pollution is reportedly associated with the exacerbation of respiratory diseases. In this study, we assessed the effects of air pollution on respiratory symptoms and the health status of participants with and without chronic respiratory diseases.MethodsParticipants (n=2753) with and without chronic respiratory diseases who visited healthcare facilities in Japan during February from 2010 to 2015 filled out a self-report questionnaire regarding their symptoms and perceived health status. Participants were followed up during April-May and June-July.ResultsOxidant concentrations were associated with respiratory symptoms, overall health, and quality of life (QoL). Suspended particulate matter (SPM) and particulate matter <2.5 μm levels were associated with physical fitness; SPM was also associated with QoL. Recent experience of an Asian sand dust event had a significant effect on allergic symptoms, change in health, and QoL.ConclusionsRespiratory symptoms were more strongly affected by oxidants than by other pollutants. Significant associations of air pollutants were found with a comprehensive range of items related to perceived health status, including overall health and QoL. Although the effects of air pollutants on respiratory symptoms and health status were more apparent among patients with respiratory diseases, the adverse effects of air pollutants were significant even among participants without such conditions.

A Novel Method for Automatic Identification of Respiratory Disease from Acoustic Recordings.

This paper evaluates the use of breath sound recordings to automatically determine the respiratory health status of a subject. A number of features were investigated and Wilcoxon Rank Sum statistical test was used to determine the significance of the extracted features. The significant features were then passed to a feature selection algorithm based on mutual information, to determine the combination of features that provided minimal redundancy and maximum relevance. The algorithm was tested on a publicly accessible respiratory sounds database. With the testing dataset, the trained classifier achieved accuracy of 87.1%, sensitivity of 86.8% and specificity of 93.6%. These are promising results showing the possibility of determining the presence or absence of respiratory disease using breath sounds recordings.

Detection and identification of dust mite allergens in the air conditioning filters in Chandigarh, India.

Modern lifestyle with the increasing use of air conditioner (AC) has been linked with breathing difficulties, irritation, dryness, and other symptoms. Hence, dust mites were isolated from AC filters, which causes allergic diseases. A total of 95 dust samples were collected from AC filters from hospitals, guest house, office, school, and homes in Chandigarh, India. The highest concentration of dust mites was detected from hospitals (9/g), offices (7/g), households (6/g), guest houses (3/g), and schools (0/g). Based on the morphology of dust mites observed under a light microscope, Dermatophagoides and Acarus species were found most common. Indoor air quality was also monitored to find out their relation with dust mites present in AC filters. Further, the respiratory health status of indoor facility users was also assessed using a standard questionnaire as a study tool. It was seen that 55.3% of male among the total respondents were having an allergy and only 44.7% of the females had an allergy. The allergy among the male respondents (55.3%) was significantly more (p < 0.05) in comparison with female respondents (44.7%). Some of the respondents also reported a family history of rhinitis (31.9%), asthma (12.8%), recurrent urticaria (6.4%), and conjunctivitis (6.4%). Interestingly, 23.4% of study participants reported that they get disturbed by the use of AC and house dust was found to be the most triggering factor in enhancing the symptoms of allergy. Thus, it is recommended that air conditioner filters should be cleaned regularly to prevent the accumulation of the dust mites and related allergens on filter dust.

Respiratory health status is associated with treatment outcomes in pulmonary tuberculosis.

<sec id="st1"> <title>BACKGROUND</title> The association between respiratory impairment and tuberculosis (TB) treatment outcomes is not clear. </sec> <sec id="st2"> <title>METHODS</title> We prospectively evaluated respiratory health status, measured using the Saint George's Respiratory Questionnaire (SGRQ), in a cohort of new adult pulmonary TB cases during and up to 18 months following treatment in India. Associations between total SGRQ scores and poor treatment outcomes of failure, recurrence and all-cause death were measured using multivariable Poisson regression. </sec> <sec id="st3"> <title>RESULTS</title> We enrolled 455 participants contributing 619 person-years at risk; 39 failed treatment, 23 had recurrence and 16 died. The median age was 38 years (interquartile range 26-49); 147 (32%) ever smoked. SGRQ scores at treatment initiation were predictive of death during treatment (14% higher risk per 4-point increase in baseline SGRQ scores, 95%CI 2-28, P = 0.01). Improvement in SGRQ scores during treatment was associated with a lower risk of failure (1% lower risk for every per cent improvement during treatment, 95%CI 1-2, P = 0.05). Clinically relevant worsening in SGRQ scores following successful treatment was associated with a higher risk of recurrence (15% higher risk per 4-point increase scores, 95%CI 4-27, P = 0.004). </sec> <sec id="st4"> <title>CONCLUSION</title> Impaired respiratory health status was associated with poor TB treatment outcomes. The SGRQ may be used to monitor treatment response and predict the risk of death in pulmonary TB. </sec>.