The study examined the utilization of block chain technology for effective circulation control in university libraries in Southeast, Nigeria. The study employed descriptive survey research design. The population of the study comprised of 472 librarians in 10 federal and state-owned universities in South-East, Nigeria. Total enumeration technique was used to study the entire population of librarians in the study area. Online structured questionnaire was used to collect the opinions of the librarians due to the constraint of distributing and accessing the respondents physically as a result of the ASUU strike. WhatsApp Groups of the various state chapters of Nigerian Library Association (NLA) in South-East Nigeria were used as method of sharing the link of the online questionnaire. Data collected were analyzed using frequency count, mean and standard deviation. The findings revealed among other things that, there was no extent of utilization of block chain technology among the university libraries studied for record keeping, tracking of transactions of users, reservation of resources, charging and discharging of information resources in university libraries in Southeast, Nigeria as there was a mean score of 1.61 for keeping and tracking records of registered users. However, it was agreed that, utilization of blockchain technology will facilitate effective circulation control in the university libraries. Lack of awareness, technophobia, inadequate skills and competence and inadequate technological facilities are the major challenges associated with the utilization of block chain technology in university libraries. The study recommended among other things that; university management should organize in-house training of librarians in the use of blockchain technology. Also, adequate technological facilities should be acquired and the work environment in the university libraries should be conducive for librarians.