Residual Pattern Research Articles

Aspergillus fumigatus hydrophobin functional amyloids

Long-time perceived as aberrant conformations associated to disease, it is now established that proteins can adopt the amyloid fold to perform their function. Hydrophobins are fungal proteins characterized by a conserved amphipathic profile and an idiosyncratic pattern of cysteine residues involved in four disulfide bridges. Their functions are due to their remarkable physicochemical properties. These proteins are secreted in a soluble form that self-assembles at hydrophobic/hydrophilic or air/water interfaces to form amphipathic layers consisting of protein amyloids with a rodlet morphology.

A field experiment characterizing variable detection rates during plant surveys.

Surveys aimed at finding threatened and invasive species can be challenging due to individual rarity and low and variable individual detection rates. Detection rate in plant surveys typically varies due to differences among observers, among the individual plants being surveyed (targets), and across background environments. Interactions among these 3 components may occur but are rarely estimated due to limited replication and control during data collection. We conducted an experiment to investigate sources of variation in detection of 2 Pilosella species that are invasive and sparsely distributed in the Alpine National Park, Australia. These species are superficially similar in appearance to other yellow‐flowered plants occurring in this landscape. We controlled the presence and color of flowers on target Pilosella plants and controlled their placement in plots, which were selected for their variation in cover of non‐target yellow flowers and dominant vegetation type. Observers mimicked Pilosella surveys in the plots and reported 1 categorical and 4 quantitative indicators of their survey experience level. We applied survival analysis to detection data to model the influence of both controlled and uncontrolled variables on detection rate. Orange‐ and yellow‐flowering Pilosella in grass‐ and heath‐dominated vegetation were detected at a higher rate than nonflowering Pilosella. However, this detection gain diminished as the cover of other co‐occurring yellow‐flowering species increased. Recent experience with Pilosella surveys improved detection rate. Detection experiments are a direct and accessible means of understanding detection processes and interpreting survey data for threatened and invasive species. Our detection findings have been used for survey planning and can inform progress toward eradication. Interaction of target and background characteristics determined detection rate, which enhanced predictions in the Pilosella eradication program and demonstrated the difficulty of transferring detection findings into untested environments.

Dissipation and Residue Pattern of Dinotefuran, Fluazinam, Indoxacarb, and Thiacloprid in Fresh and Processed Persimmon Using LC-MS/MS.

Pesticides which are diluted and sprayed according to the pre-harvest interval (PHI) are generally decomposed and lost through various factors and pathways, and the leftover pesticides are known as residual pesticides. This study aims to determine the dissipation of residual amounts of dinotefuran, fluazinam, indoxacarb, and thiacloprid in persimmon and the changes in the concentration of various processing products. Pesticide spraying is performed in accordance with the GAP (good agricultue practice) of Korea, and the processed products are manufactured using a conventional method after removing the skin of persimmons. The modified QuEchERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method and an optimized method using LC-MS/MS (liquid chromatography mass spectrometry) is implemented to analyze the residual pesticides. The linearity, recovery, and LOQ (limit of quantitation) are presented to verify the analysis method. The amount of residual pesticides tested decreases significantly in a time-dependent manner, regardless of the minimal dilution effect present due to growth. The residual concentration does not vary significantly during the processing stage despite the removal of the systemic pesticides, dinotefuran and thiacloprid. The residues of non-systemic pesticides, fluazinam and indoxacarb, are typically removed by the peeling removal and processing methods. The reduction factor of dinotefuran, whose residual concentration is increased, is less than 1, and the absolute amount of pesticides is decreased through processing. The results of this study can be used as the scientific basis data to ensure the safety of residual pesticides in processed products in the future.

Effect of radiation defects on the early stages of nanoindentation tests in bcc Fe and Fe-Cr alloys

Classical molecular dynamics (MD) simulations of nanoindentation tests are performed in defect-free at 300, 600 and 1000 K and defected crystals at 300 and 600 K of pure Fe and Fe-9Cr alloy. The aim of the work is to evaluate the effect of the presence of various defects specific to neutron/heavy ion irradiation (i.e., voids, dislocation loops and Cr precipitates) on the material response during the early stages of nanoindentation (i.e., at indentation depths up to 20 Å). We establish that even a relatively large density of the radiation defects (∼1024 m−3) does not induce any significant change in the material response, i.e., it is not unambiguously detectable at the force-depth curves neither in pure Fe nor in Fe-9Cr alloys. The macroscopic parameters, which can be derived from these curves, such as hardness and reduced modulus, calculated in the crystals with and without radiation defects also cannot clearly reveal the contribution from the presence of the radiation defects given the resulting uncertainty of their extraction. However, several distinct features typical for nanoindentation tests observed in crystals with radiation defects only were identified, such as a) obstruction of emission of dislocation loops under the indenter during loading for crystals with precipitates and dislocation loops, and b) special residual imprint pattern for crystals with dislocation loops. The results of this work provide useful data for the parameterization and validation of the higher-scale methods, such as dislocation dynamics and (crystal plasticity-) finite-element method. The details of the transferability of MD results to these methods are also discussed.

Adolescents’ motivation for family travels: cross-culture/cross-country evidence

ABSTRACT This study used a measurement model to investigate adolescents in 25 countries, in an effort to understand their motivations for attending family travel. In general, both cultural region and culture type were related to travel motivation patterns and studentized residual patterns. In addition, overall, a country’s level of development and its cultural dimensions were more strongly correlated with females’ travel motivations of interpersonal escape and seeking than with those motivations in males. We also confirmed a U-shaped relationship of cultural response bias in certain measures of motivation components in connection with three indicators: masculinity, uncertainty avoidance, and family score.

Sedimentary spectrum and potential ecological risks of residual pharmaceuticals in relation to sediment-water partitioning and land uses in a watershed

Pharmaceutical residues in river surficial sediment are prone to anthropogenic impacts and environmental factors in watershed, but the mechanisms remain unclear. This study attempted to reveal surficial sediment-water pseudo-partitioning and anthropogenic (land use) patterns of pharmaceutical residues in surficial sediment among 23 subwatersheds of Jiulong River, southeast China with a gradient of urban land use percentile in dry and wet seasons. Thirty-eight out of target 86 compounds from six-category pharmaceuticals were quantified and ranged from below the quantification limits (0.001 mg kg−1 dry mass) up to 8.19 mg kg−1 dry mass (chlortetracycline) using a developed SPE-HPLC-MS/MS protocol. Antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) collectively dominated sedimentary pharmaceutical residues for 34.5–99.8% of the total quantified compounds (median at 92%). Land uses in subwatersheds showed high consistency with sedimentary pharmaceutical residues in the dry season rather than the wet season, especially for human use only and veterinary use only compounds. Surficial sediment-water partitioning of pharmaceutical compounds influenced their sedimentary residues regardless of season, which were determined by properties of compound and surficial sediment interactively. All tetracycline compounds, trimethoprim (sulfonamides synergist), caffeine (central nervous system drug), and oxfendazole (antiparasitic drug) were quantified to pose high potential ecological risks to aquatics. Findings of this study suggest that pseudo-persistent legacy of human and veterinary pharmaceuticals requires a wider coverage of pharmaceutical compounds for a comprehensive ecological assessment in the environment and more involvement of anthropogenic impacts and socioeconomic factors in the future studies.

Variability of subtidal flow in a narrow meandering stratified estuary

A 3D numerical model was set up to investigate the spatial and temporal variations of subtidal circulation in a narrow meandering stratified estuary: the Adour Estuary (France). The hydrodynamic model was validated with field data and reproduced satisfactorily tide, current and salinity observations. The results highlighted a fortnightly switch in the residual flow structure and a variation in residual circulation intensity between low and high river discharge conditions. During neap tides, an exchange flow was observed as the baroclinicity dominated the residual circulation. During spring tides, the advection and barotropic pressure gradient drove the subtidal flow and an outflow over the whole water column took place. Residual flows were twice as high during high river discharge as during low river discharge. Secondary cross-channel residual circulation was driven by the estuarine morphology and the along-channel residual circulation. A secondary circulation cell was observed when a density-driven exchange flow occurred (neap tide). The meanders induced a variation of the sense of rotation of the circulation cell. A constriction of the channel has been shown to strengthen the residual circulation by flow conservation. Finally, we observed that the freshwater Froude number and the Mixing number Geyer and MacCready (2014) were able to distinguish residual flow pattern between idealised simulation cases.

FVC: An End-to-End Framework Towards Deep Video Compression in Feature Space.

Deep video compression is attracting increasing attention from both deep learning and video processing community. Recent learning-based approaches follow the hybrid coding paradigm to perform pixel space operations for reducing redundancy along both spatial and temporal dimentions, which leads to inaccurate motion estimation or less effective motion compensation. In this work, we propose a feature-space video coding framework (FVC), which performs all major operations (i.e., motion estimation, motion compression, motion compensation and residual compression) in the feature space. Specifically, a new deformable compensation module, which consists of motion estimation, motion compression and motion compensation, is proposed for more effective motion compensation. In our deformable compensation module, we first perform motion estimation in the feature space to produce the motion information (i.e., the offset maps). Then the motion information is compressed by using the auto-encoder style network. After that, we use the deformable convolution operation to generate the predicted feature for motion compensation. Finally, the residual information between the feature from the current frame and the predicted feature from the deformable compensation module is also compressed in the feature space. Motivated by the conventional codecs, in which the blocks with different sizes are used for motion estimation, we additionally propose two new modules called resolution-adaptive motion coding (RaMC) and resolution-adaptive residual coding (RaRC) to automatically cope with different types of motion and residual patterns at different spatial locations. Comprehensive experimental results demonstrate that our proposed framework achieves the state-of-the-art performance on three benchmark datasets including HEVC, UVG and MCL-JCV.

A Pipeline for Automated Processing of Declassified Corona KH-4 (1962–1972) Stereo Imagery

The Corona KH-4 reconnaissance satellite missions from 1962-1972 acquired panoramic stereo imagery with high spatial resolution of 1.8-7.5 m. The potential of 800,000+ declassified Corona images has not been leveraged due to the complexities arising from handling of panoramic imaging geometry, film distortions and limited availability of the metadata required for georeferencing of the Corona imagery. This paper presents Corona Stereo Pipeline (CoSP): A pipeline for processing of Corona KH-4 stereo panoramic imagery. CoSP utlizes a deep learning based feature matcher SuperGlue to automatically match features point between Corona KH-4 images and recent satellite imagery to generate Ground Control Points (GCPs). To model the imaging geometry and the scanning motion of the panoramic KH-4 cameras, a rigorous camera model consisting of modified collinearity equations with time dependent exterior orientation parameters is employed. The results show that using the entire frame of the Corona image, bundle adjustment using well-distributed GCPs results in an average standard deviation (SD) of less than 2 pixels. The distortion pattern of image residuals of GCPs and y-parallax in epipolar resampled images suggest that film distortions due to long term storage as likely cause of systematic deviations. Compared to the SRTM DEM, the Corona DEM computed using CoSP achieved a Normalized Median Absolute Deviation (NMAD) of elevation differences of ~4 m over an area of approx. 4000 $km^2$. We show that the proposed pipeline can be applied to sequence of complex scenes involving high relief and glacierized terrain and that the resulting DEMs can be used to compute long term glacier elevation changes over large areas.

Dissipation and persistence pattern of chlorantraniliprole residues in tomato under open field conditions and its estimation through UHPLC-PDA

Dissipation and persistence pattern of chlorantraniliprole residues in tomato under open field conditions and its estimation through UHPLC-PDA

The Effect of Induction Heating Stress Remedies on piping reliability

To address the effect of Intergranular stress corrosion cracking (IGSCC) on the probability of a leak in BWR piping, we have introduced some changes to the model of IGSCC for the Probabilistic fracture mechanics PRAISE code. This semi-empirical model is based on experimental and field data compiled from several sources. Using probabilistic techniques, the model addresses various stress corrosion phenomena, including crack growth, crack initiation, and linking of multiple cracks. The model also considers the effect of residual stresses in addition to cyclic stresses resulting from normal plant operation. Residual stresses which are an inherent result of conventional welding processes have long been known to play an important role in the failure of structural components. Such stresses can have a beneficial or detrimental influence, depending primarily on whether they are tensile or compressive at the inside surface of the pipe. Residual stresses undoubtedly are influential in both the initiation and propagation of cracks. The purpose of this paper is to review the influence of residual stresses on the reliability of piping under IGSCC. A procedure such as induction heating stress improvement (IHSI) is a means of altering the residual stress pattern in a pipe. Examples of the use of this technique to the initiation and growth of stress corrosion cracks in pipes are presented for various pipe sizes and residual stress distributions. The effectiveness of IHSI as an eternal countermeasure for IGSCC depends upon the level of service stress as well as the crack size and its large benefit is immediately apparent.

Behavior of structural lightweight concrete produced with expanded clay aggregate and after exposure to high temperatures

The residual compressive strength of eight lightweight concrete mixtures containing three commercial grading (Liapor HD 5 N, Liapor HD 7 N, and Liapor 8F) of coarse lightweight aggregate (LWA) were determined after to expose at high temperatures. Eight mixes were produced, two by normal weight aggregate and the rest by different types of LWA. The produced concrete was analyzed after high temperature exposure and the effect of using LWA, the type of LWA, and compaction method was studied. To do so, visual inspection, residual compressive strength, crack pattern, spalling, and thermoanalytical analysis were conducted. Generally, it could be concluded that concrete formulations with LWA behave more advantageous up to 500 °C, compared to those with quartz gravel aggregates. Moreover, this study found that an ideal type of LWA to produce structural concrete was Liapor HD 5 N, which was used for producing the mixes L1 and L3.

Experimental and numerical studies of laser-welded slender stainless steel I-section columns

Stainless steel has extensive applications in the construction industry because of its attractive appearance, unique corrosion resistance, durability, and superior mechanical properties. Laser-welding is a manufacturing process that is suitable for connecting various steel and stainless steel. High precision and low heat input characteristics make it have smaller heat-affected zones than the traditional welding process, resulting in lower thermal distortions and residual stress to give it increased load-carrying capacity. The present paper focuses on investigating the structural response of laser-welded slender stainless steel I-section columns to address the lack of test data. Nine stub columns tests and ten long columns tests were analysed for slender I-sections of austenitic laser-welded stainless steel of two stainless steel alloys (austenitic EN 1.4301 and EN 1.4307). Additionally, the material tensile coupon tests, residual stress measurements, and initial geometric imperfection measurements were performed. The observed results verified a representative residual stress pattern. The finite element model was validated based on the test results and parametric analysis was carried out on laser-welded slender stainless steel I-section axially compressed members. Further, the study evaluated the cross-sectional and column buckling resistances for European code EN 1993-1-4, American Design Guide AISC 27, and Continuous Strength Method. Interestingly, the continuous strength method reflected significantly better buckling behaviour of slender I-sections. Although this method gives more accurate results than the code predictions, slight conservatism predictions were still found for slender I-section columns with room for improvement.

Prediction of residual stresses in high-strength S690 cold-formed square hollow sections using integrated numerical simulations

In general, residual stresses are induced in structural members during various fabrication processes, such as welding, bending, press-braking, folding, flame cutting and punching. The presence of those residual stresses in cold-formed square hollow sections (CFSHS) primarily caused by i) transverse bending (or cold-forming), and ii) longitudinal welding, is widely considered to have modified both initial stress and strain conditions of these steel members significantly. Hence, these residual stresses are widely considered to have significant adverse effects onto the structural performance of these CFSHS under various actions.In order to examine and quantify both magnitudes and distributions of these residual stresses in S690 CFSHS, an investigation is undertaken to measure residual stresses due to transverse bending and longitudinal welding. Moreover, an approach of integrated numerical simulations is adopted in which a total of three co-ordinated finite element models are established together with various element types and block data transfers to generate compatible meshes for the following three analyses: i) two-dimensional plane-strain bending analyses with large plastic deformations and springback, ii) three-dimensional heat transfer analyses for transient temperature distributions under a heat source, and iii) three-dimensional thermomechanical analyses for welding-induced residual stresses.The predicted results of these three analyses have been carefully calibrated against various experimental data, such as surface temperatures during welding, and residual stresses and strains after welding. Good comparisons between the measured and the predicted data of these S690 CFSHS are demonstrated. The complete residual stress distributions within typical S690 CFSHS due to transverse bending and longitudinal welding are illustrated in three-dimensional plots while simplified residual stress patterns of these sections with specific values and parameters are also provided for subsequent advanced structural analyses and design.The proposed modelling technique for transverse bending and longitudinal welding with compatible meshes of two-dimensional and three-dimensional models with various element types and block data transfers is demonstrated to be highly effective. The technique is readily applicable to simulate residual stresses of all fabricated sections manufactured with transverse bending and longitudinal welding, and, thus, the simulated residual stresses can be employed in subsequent structural analyses of all fabricated members.

Efficiency in education: primary and secondary schools in Italian regions

ABSTRACT By using stochastic frontier analysis, single- and multiple-output methods, this paper empirically investigates the efficiency of Italian regions in providing public primary and secondary education for the period 2011–18. The analysis detects strong interregional differences, outlining a clear North–South geographical pattern. To single out the reasons for the poor performance of Southern regions, context variables (per capita gross domestic product, poverty, institutional quality, adult education) are considered and shown to be highly relevant in shaping regional efficiency. Finally, when interregional disparities in socio-economic factors are accounted for, no residual geographical pattern in regional efficiency emerges.

Characterization of SARS-CoV-2 isolated from a patient in Iran compared to SARS-CoV-2 different variants

Since the onset of the global epidemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), whole genome sequencing of virus in all countries has been considered to track and predict virus transmission and variation patterns. In the current study we reported a novel complete genome sequence of SARS-CoV-2 isolated from Iran. Genomics variations and protein sequences were evaluated for the isolated sequence and seven Iranian complete genome sequences of SARS-CoV-2 from NCBI using the reference genome of the SARS-CoV-2 Wuhan-Hu-1. The results showed six nucleotide substitutions. The multiple sequence alignment of the spike protein of the Wuhan-Hu-1 strain and the emerging variants indicated similar its residue pattern in the current sequence to the Wuhan-Hu-1 strain. There were relatively similar binding affinity and residues involved in the interactions of the spike receptor-binding domain (RBD) of the Wuhan-Hu-1 strain, the variants and Hormozgan With angiotensin-converting enzyme 2 (ACE2). Tracing the phylogeny of virus indicated distinct clustering of Iranian variants in branches close to the Asian countries. The mutation effect study on the function of proteins predicted neutral impact of all six nucleotide substitutions. However, the free energy calculations indicated a decreasing the protein stability related to the mutations. This data, consistent with similar studies, showed that despite the high similarity in the nucleotide sequence of the SARS-CoV-2, the mutation pattern varies from country to country. Therefore, any country can benefit from these studies to track and find appropriate strategies for treating and controlling the epidemic. Communicated by Ramaswamy H. Sarma

Late Miocene Conidae (Mollusca: Gastropoda) of Crete (Greece). Part 1: genera Conilithes Swainson, 1840 and Conus (Kalloconus) da Motta, 1991

Conidae is a diverse family of carnivorous marine gastropods. They rapidly diversified during the Miocene and now they inhabit tropical and subtropical seas. Here we attempt to provide the first inventory of fossil conids from the late Miocene of Crete (Greece). This paper deals with the genera Conilithes and Conus (Kalloconus) da Motta, 1991 and will be followed by papers presenting other genera of the family. Using UV light, we described the residual colour patterns of eleven species, of which three are new: Conilithes herodus n. sp., Conus (Kalloconus) helladicus n. sp and Conus (Kalloconus) asterousiaensis n. sp. One species is in open nomenclature: Conilithes sp.. Six species are first recorded in the late Miocene of Crete: Conilithes brezinae (Hoernes & Auinger, 1879), Conilithes striatulus (Brocchi, 1814), Conus (Kalloconus) neumayri Hoernes & Auinger, 1879, Conus (Kalloconus) hendricksi (Harzhauser & Landau, 2016), Conus (Kalloconus) gulemani Erünal-Erentöz, 1958 and Conus (Kalloconus) letkesensis (Harzhauser & Landau 2016). Conilithes antidiluvianus (Bruguière, 1792) is the only species already recorded by past Greek authors. Firstly, our study reveals that only two species are restricted to the late Miocene of Crete (Conilithes herodus n. sp. and Conus (Kalloconus) helladicus n. sp.). Secondly, we found deep relationships with the conid assemblage from the Langhian of Paratethys (six shared species). This result could be interpreted as a conid fauna, present and widely distributed since the Langhian-Serravallian in both the Paratethys and the eastern Proto-Mediterranean. This fauna disappeared from Paratethys during the Serravallian, but probably persisted in the eastern Proto-Mediterranean, as suggested by the relationships with the Serravallian of Turkey and the Tortonian of Crete (this work). On the other hand, the weak relationships with the late Neogene of Italy might be biased because, for the comparison with Italian faunas, we used works that illustrated Conidae without UV light.

Evaluation and risk assessment of organochlorine pesticide residues in some fish species in south-south Nigeria

This study reports the presence, distribution pattern, concentration levels and health risk assessment of organochlorine pesticide residues in fresh and cured fish species in South-South Nigeria. The concentrations of organochlorine pesticides in fresh and cured fish were analysed with Gas Chromatography/ Mass Spectrophotometry (GC-MS) after Soxhlet extraction of the fish species. The study revealed that no organochlorine pesticide was present in fresh fish. However, cured fish species from all the markets sampled had at least two organochlorine pesticide residues which ranged from endosulfan (0.252±0.0022–748±0.004ug/g), lindane (0.386±0.010–0.443±0.009 ug/g), heptachlor-epoxide (0.328±0.005–3.162±0.010ug/g), ortho-para-dichloro-diphenyl-trichloro-ethane (o,p’-DDT) (0.021±0.001–0.180±0.030ug/g) and aldrin (0.140±0.040–2.770±0.020ug/g). These levels are far higher than the maximum residual limit and allowable daily intake values recommended by World Health Organization (WHO) and Food and Agricultural Organization (FAO). There were no pesticide residues in fresh fish probably because the fisher folks in the study area may have abolished the use of obnoxious fishing methods due to the awareness of threats to the aquatic ecosystem. The high percentage occurrences, amounts and distribution of organochlorine pesticides in cured-fish from markets sampled could be as a result of the fact that these organochlorine pesticides were consistently used in the study area by fish processors, distributors and sellers. Human risk assessment of this study revealed a potential danger in the consumption of cured-fish containing the organochlorine pesticides seen in the study.

Quantifying charge state heterogeneity for proteins with multiple ionizable residues

Ionizable residues can release and take up protons and this has an influence on protein structure and function. The extent of protonation is linked to the overall pH of the solution and the local environments of ionizable residues. Binding or unbinding of a single proton generates a distinct charge microstate defined by a specific pattern of charges. Accordingly, the overall partition function is a sum over all charge microstates and Boltzmann weights of all conformations associated with each of the charge microstates. This ensemble-of-ensembles description recast as a q-canonical ensemble allows us to analyze and interpret potentiometric titrations that provide information regarding net charge as a function of pH. In the q-canonical ensemble, charge microstates are grouped into mesostates where each mesostate is a collection of microstates of the same net charge. Here, we show that leveraging the structure of the q-canonical ensemble allows us to decouple contributions of net proton binding and release from proton arrangement and conformational considerations. Through application of the q-canonical formalism to analyze potentiometric measurements of net charge in proteins with repetitive patterns of Lys and Glu residues, we determine the underlying mesostate pKa values and, more importantly, we estimate relative mesostate populations as a function of pH. This is a strength of using the q-canonical approach that cannot be replicated using purely site-specific analyses. Overall, our work shows how measurements of charge equilibria, decoupled from measurements of conformational equilibria, and analyzed using the framework of the q-canonical ensemble, provide protein-specific quantitative descriptions of pH-dependent populations of mesostates. This method is of direct relevance for measuring and understanding how different charge states contribute to conformational, binding, and phase equilibria of proteins.

Clinical Significance of Endoscopic Response Evaluation to Predict the Distribution of Residual Tumor after Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma.

To appropriately adopt the organ preservation approach, including subsequent chemoradiotherapy (CRT) in patients who respond to neoadjuvant chemotherapy (NAC), the distribution of residual disease, including pathological lymph nodes (LNs) and recurrence site, needs to be recognized preoperatively. This study was designed to evaluate whether endoscopic response evaluation can predict residual tumor distribution. Patients with esophageal squamous cell carcinoma who underwent transthoracic esophagectomy (TTE) were retrospectively reviewed. Endoscopic responder (ER) to NAC was defined according to primary tumor endoscopic findings. Recurrence-free survival (RFS), overall survival (OS), and residual tumor patterns were compared between groups. Of 193 patients, 40 (20%) were classified as ER. ERs showed significantly better RFS and OS. The pN location was found within the primary tumor and cN field in 88% of ERs, which was significantly higher than non-ERs at 63% (p = 0.004). Furthermore, the postoperative recurrence incidence in the distant organ was significantly lower in the ERs than the non-ERs (8%, 32%, respectively, p = 0.002). Residual disease, including postoperative initial recurrence, existed within the same field as the primary tumor and cN in 88% of ERs, significantly higher than 42% in the non-ERs (p < 0.001). Endoscopic response evaluation can preoperatively predict distribution of residual tumors after NAC, which could help radiation field selection in subsequent definitive CRT when patients prefer to omit TTE. Along with improvements in NAC response rate, this could facilitate organ preservation in patients who respond to NAC.