In this study, an innovative approach that combines least square support vector regression (LSSVR) with uncertainty theory to enhance its performance in dealing with low-quality or imprecise data from real-world be proposed. The resulting model, called uncertain least square support vector regression (ULSSVR), incorporates chance constraints and simplified parameter selection, which are critical to handle imprecise observations. A numerical algorithm called the conjugate residual method (CR) is introduced to reduce the computational complexity of the model solution. The experimental results using both small and medium-sized datasets demonstrate the superior performance of ULSSVR in terms of prediction accuracy and generalization ability compared to other models such as uncertain support vector regression (USVR), uncertain linear lodel, uncertain polynomial model, and uncertain growth models. ULSSVR not only improves prediction accuracy by at least 28.49% but also demonstrates faster computational speed. Overall, ULSSVR presents a promising solution for data science and internet applications where dealing with imprecise and low-quality data is a common challenge.