Heart Rate Variability Research Research Articles

History of the creation and activity of the Functional Neurology Research Unit over 30 years

Background: The Functional Neurology Research Unit (FNRU) was created in 1992 at the State University of Medicine and Pharmacy of the Republic of Moldova. The activity of the scientific unit was essentially based on the concept of Functional Neurology, which was published in an article in the prestigious Italian journal Functional Neurology (1998) and continues to be further developed by Professors I. Moldovanu and V. Vovc. Conclusions: Physiological aspects in the researches carried out by collaborators of the FNRU concerned research of breathing pattern, autonomic parameters of suprasegmental and segmental level (research of heart rate variability, segmental vegetative samples, etc.), reactivity of cerebral vessels to modeled hypocapnia, trigeminal, somesthetic, visual, auditory evoked potentials in patients with chronic headache, etc. To conclude, the scientific objectives of the research carried out by the collaborators of the Functional Neurology Research Unit during 30 years of activity – the development of the problem of identifying and using the huge, so far still insufficiently researched possibilities of the “reserves” of the human brain for therapeutic purposes (treatment of chronic pain, movement disorders as a result of organic brain lesions, autonomic disorders, etc.) in the context of a new, modern and advanced understanding of the relationship and interaction of the human brain, psyche and body within a social background which is the essence of the functional neurology.

Изучение сердечного ритма студенческой молодежи при занятиях физической культурой и в состоянии покоя

Importance. The problem of health level of the young generation is considered. The aim of the work is to conduct research of heart rate variability to identify the influence of physical training on the students’ health. Research Methods. Students of 1–2 courses (158 people) of I.T. Trubilin Kuban State Agricultural University took part in the experiment. The research methods are the study of parameters series related to the analysis of heart rhythm and the use of the Ruffier test. The research used a specially selected set of exercises, which both positively affects the health of students and allows to assess the indicators of interest. At each stage of health indicators assessment, different methods of physical culture are used: a special complex, Ruffier test exercises, game and competitive sports, as well as warm-up and relaxation exercises of the final part. Results and Discussion. At each stage, the differences of indicators between male and female are highlighted. The first stage measured the heart rate during physical training and at rest using a special health-improving complex of moderate intensity, taking into account the individual characteristics of students. Then the mode of heart rate variability and its amplitude in different situations are recorded. With the help of Ruffier test the level of students’ cardiac performance and the limits of the difference between the minimum and maximum values of intervals between the beginnings of two neighboring cardiac cycles are determined. These are evaluated when performing the complex “lying down recreation – squatting” – a complex specially designed for taking the Ruffier test. The autonomic nervous system is studied, in particular, the activity of sympathetic and parasympathetic departments in different states, the predominance of one department over another and their features. The most effective method of their study is determined to involve students in games of volleyball, badminton and inclusion of competitive exercises. The level of tension index of student youth is evaluated. Conclusion. General conclusions are made on research results, high influence of physical culture and sports on students’ heart work and their health in general is revealed.

High-resolution rhythmocardiography and heart rate variability research in coronary artery bypass graft surgery

Clinical approbation of high-resolution rhythmocardiography (RCG) and analysis of heart rate variability (HRV) were performed to assess the cardiovascular status in real time before, during, and after coronary artery bypass graft surgery (CABG) performed for myocardial revascularization in patients (pts) with unstable angina.At each stage of the operation, a characteristic pattern of violation of the HRV wave structure was observed on the rhythm cardiogram (ECG). Most of the arrhythmias on the ECG were associated with the surgeon’s manipulations during CABG. The RCG method with high resolution showed minimal pathological changes in HRV. A standard assessment of the cardiovascular system was performed, 123 patients were evaluated by RCG using HRV analysis. Before, during (in monitor mode), and after the operation, the original hardware and software computer complex was applied.Thus, the high-resolution RCG method can be used to diagnose the cardiovascular status in real time during CABG surgery.

Heart Rate Variability - State of Research and Clinical Applicability

Heart Rate Variability - State of Research and Clinical Applicability Abstract. Heart rate variability is considered a marker of autonomous nervous system activity. Autonomic imbalance is found as a common component in a wide range of pathologies. It has been found to precede the onset of pathologic states and correlates with therapy response. In addition, heart rate variability at rest is a psychophysiological phenomenon with broad significance. Psychological experience affects physiological homeostasis, including immune processes, via the autonomous nerve system, which biologically underpins psychosomatic effects and makes them measurable by heart rate variability. The autonomous nerve system as the interface of this psychophysiological regulation is becoming increasingly important in heart rate variability research and allows a better understanding of the interactions between psyche, lifestyle, autonomous regulation and chronic illness. It requires a systemic, cross-organ view as well as an orientation towards long-term processes. The assessment and normalization of autonomic imbalance thus represents a novel therapeutic strategy from which numerous interventions and lifestyle modifications can be derived. Interventions that strengthen the vagal tone (aerobic or moderate physical training, relaxation techniques, vagus nerve stimulation, etc.) are becoming increasingly important. Despite the simple non-invasive measurement and popularity as a research instrument, interpretation is complex, and clinical implementation has been reluctant so far. Nevertheless, guidelines and data sets of reference values exist for users to apply.

Phase synchronization in electroencephalographic recordings prognosticates outcome in paediatric coma.

Brain injury from trauma, cardiac arrest or stroke is the most important cause of death and acquired disability in the paediatric population. Due to the lifetime impact of brain injury, there is a need for methods to stratify patient risk and ultimately predict outcome. Early prognosis is fundamental to the implementation of interventions to improve recovery, but no clinical model as yet exists. Healthy physiology is associated with a relative high variability of physiologic signals in organ systems. This was first evaluated in heart rate variability research. Brain variability can be quantified through electroencephalographic (EEG) phase synchrony. We hypothesised that variability in brain signals from EEG recordings would correlate with patient outcome after brain injury. Lower variability in EEG phase synchronization, would be associated with poor patient prognosis. A retrospective study, spanning 10 years (2000–2010) analysed the scalp EEGs of children aged 1 month to 17 years in coma (Glasgow Coma Scale, GCS, <8) admitted to the paediatric critical care unit (PCCU) following brain injury from TBI, cardiac arrest or stroke. Phase synchrony of the EEGs was evaluated using the Hilbert transform and the variability of the phase synchrony calculated. Outcome was evaluated using the 6 point Paediatric Performance Category Score (PCPC) based on chart review at the time of hospital discharge. Outcome was dichotomized to good outcome (PCPC score 1 to 3) and poor outcome (PCPC score 4 to 6). Children who had a poor outcome following brain injury secondary to cardiac arrest, TBI or stroke, had a higher magnitude of synchrony (R index), a lower spatial complexity of the synchrony patterns and a lower temporal variability of the synchrony index values at 15 Hz when compared to those patients with a good outcome.

A research of heart rate variability between symptomatic mitral valve prolapse syndrome and normal patients

A research of heart rate variability between symptomatic mitral valve prolapse syndrome and normal patients