In the early 1930s, when the project of scientific modernization was in full swing in Chinese Buddhist circles, Dharma Master Taixu wrote a series of essays on “Realism” (Xianshi zhuyi 現實主義, 1928–1931). These represent one of the profoundest series of writings documenting his understanding of the link between science and Buddhist epistemology/ontology, and consequently also on the role of his notion of scientific Buddhism for modern times. Aside from his meditations on the relationship between science and Buddhism, in this important series of essays Taixu also provided his more or less critical accounts on modern philosophical currents in contemporary China, including Russell’s “New Realism” and materialism. This paper aims to provide a concise reading of the above-mentioned writings by Taixu, in order to cast some new light on the understanding of Western modern philosophy in Chinese Buddhist modernism of the Republican Era, on the one hand, and to highlight the main theoretical features of Taixu’s notion of scientific Buddhism, on the other. Aside from that, I also aim to present some new insights into the otherwise overlooked aspects of the broader intellectual sphere of Chinese Buddhism of the Republican Era. As regards the broader historical and intellectual context of Taixu’s writings, the analysis provided in this article will be regarded within the framework constructed in my forthcoming article on Taixu’s philosophy in the journal Buddhist Studies Review.