An important component of economic analysis at each enterprise is the analysis of labor costs, the main purpose of which is to determine the expediency of the forms and systems of labor remuneration used at the enterprise, to determine ways of increase of labor productivity, which contributes to decrease of production cost, increase of profit and profitability, determination of the sum of the absolute and relative overexpenditures (economy) of the labor remuneration fund, investigation of the reasons why it was caused, identification of reserves, which the enterprise has to reduce expenses on labor remuneration. The article examined methodological approaches to the analysis of expenses for labor remuneration of the enterprise and the factors of their formation. The tasks to be solved in the process of analysis of labor costs and the information base used during its implementation are defined. The approaches to calculating labor productivity are revealed depending on the methods of calculation of volumes of manufactured products and the reserves of its increase are revealed. It is emphasized that the establishment of an effective mechanism of labor productivity management will help in solving the issue of equitable distribution of the obtained results of economic activity not only among the owners of the enterprise, but also among all employees who took part in the production process. It is noted that modeling and factor analysis takes a special place in the methodology of carrying out of complex analysis, the purpose of which is to identify causal connections between the previously isolated from the general aggregate of the main factors, that is, the ones that exert the most significant influence. The work outlines the stages of the control and management of wages and other payments to employees in order to organize an effective management system at the enterprise. It was established that the method of analysis of labor costs is individual for each enterprise and depends, first of all, on the goals set by management personnel. A well-grounded and complete economic analysis of labor remuneration creates conditions for successful management decisions, because it helps to monitor key trends of the enterprise development, identify the main factors influencing it and build further forecasts.