Background: The continuous and accurate monitoring of physiological signals is critical for timely medical interventions, particularly in the context of chronic disease management and elderly care. The advent of Wireless Body Sensor Networks (WBSN) and Patient Health Monitoring Systems (PHMS) promises to revolutionize healthcare by integrating real-time data collection with advanced processing and communication technologies, enabling proactive medical responses through the Internet of Things (IoT). Methods: In this study, a WBSN-PHMS framework is proposed, leveraging a network of biomedical sensors to continuously monitor vital signs such as temperature and heart rate. The system includes a gateway node that wirelessly transmits sensor data to a cloud-based storage and processing system. Physiological data are processed in real-time using advanced algorithms to detect anomalies and trigger alerts. The health status is modeled using a function g(v,w(v),∅−1(v(w))−∂i(v,∂))g(v, w(v), \varnothing^{-1}(v(w)) - \partial_i(v, \partial))g(v,w(v),∅−1(v(w))−∂i?(v,∂)), which integrates patient-specific factors and real-time physiological states. The processed data are communicated efficiently through IoT platforms, ensuring that healthcare professionals receive timely alerts via mobile applications and specialized dashboards. Results: The WBSN-PHMS demonstrated high accuracy in detecting abnormal temperature and heart rate patterns, achieving detection rates of 98.61% and 99.43%, respectively. Additionally, the system improved overall patient health monitoring by 98.42%, offering a significant advancement in patient safety and healthcare efficiency. The cost-effectiveness of the system was established with a 96.21% improvement, while energy consumption was reduced by 23%, underscoring the sustainability of the technology. Conclusion: The WBSN-PHMS proves to be a reliable and efficient healthcare monitoring system that enhances patient outcomes through real-time data analysis and rapid medical responses. The system's ability to continuously monitor and analyze physiological signals in a non-intrusive manner positions it as a vital tool in modern medical practice, with the potential to revolutionize remote patient care and monitoring.