Relative Probability Research Articles

The content of fatty acids in blood plasma in men with arterial hypertension (“ESSE-RF3” in the Novosibirsk region)

Objective. The aim of the study was to investigate the content of fatty acids (FA) in the blood plasma of Novosibirsk men (“ESSE-RF3” in the Novosibirsk region) with established and newly diagnosed arterial hypertension (HTN). Design and methods. Within the framework of the multicenter single-stage epidemiological study ESSE-RF3 in the Novosibirsk region, 1200 residents of Novosibirsk (men — 600, women — 600) aged 35–74 years were examined. The random number study included 340 men with an average age of 54,63 ± 11,34 years, of which 156 people with established HTN, 49 had AH for the first time, and 135 people without HTN. In the blood plasma, the fatty acid spectrum of blood, including omega‑3,-6,-9 FA, was determined by highperformance liquid chromatography. Results. The level of alpha-linolenic and gamma-linolenic FAs was 1,21 (p = 0,005) and 1,39 times higher (p = 0,013) in the group of men with established HTN (who did not reach the target values of blood pressure against the background of therapy), respectively. The content of gammalinolenic acid was 1,46 times higher in the group of men with the first ever detected HTN (p = 0,038) when compared with the group of men without HTN. The relative chance of HTN in men, regardless of risk factors, is directly associated with an increase in the level of gamma-linolenic FA, and inversely associated with the level of hexadecenoic FA in blood plasma. Conclusions. Thus, from the studied FA in blood plasma, an increase in the level of gamma-linolenic FA can serve as an additional informative biomarker indicating a high probability of developing HTN in men.

Classification of Chandra X-Ray Sources in Cygnus OB2

We have devised a predominantly Naive Bayes−based method to classify X-ray sources detected by Chandra in the Cygnus OB2 association into members, foreground objects, and background objects. We employ a variety of X-ray, optical, and infrared characteristics to construct likelihoods using training sets defined by well-measured sources. Combinations of optical photometry from the Sloan Digital Sky Survey (riz) and Isaac Newton Telescope Photometric Hα Survey (r I i I Hα), infrared magnitudes from United Kingdom Infrared Telescope Deep Sky Survey and Two-Micron All Sky Survey (JHK), X-ray quantiles and hardness ratios, and estimates of extinction A v are used to compute the relative probabilities that a given source belongs to one of the classes. Principal component analysis is used to isolate the best axes for separating the classes for the photometric data, and Gaussian component separation is used for X-ray hardness and extinction. Errors in the measurements are accounted for by modeling as Gaussians and integrating over likelihoods approximated as quartic polynomials. We evaluate the accuracy of the classification by inspection and reclassify a number of sources based on infrared magnitudes, the presence of disks, and spectral hardness induced by flaring. We also consider systematic errors due to extinction. Of the 7924 X-ray detections, 5501 have a total of 5597 optical/infrared matches, including 78 with multiple counterparts. We find that ≈6100 objects are likely association members, ≈1400 are background objects, and ≈500 are foreground objects, with an accuracy of 96%, 93%, and 80%, respectively, with an overall classification accuracy of approximately 95%.

Evaluation of the effect of particulate matter on construction accidents using relative probability

PM10 is known to have a great adverse effect on the human body. However, there is a lack of research analyzing the impact of PM10 on the occurrence of accidents. Accordingly, the purpose of this study is to analyze the correlation between PM10 and accidents in the construction industry and to present a new concentration group to manage accidents caused by PM10 in the construction industry. This study was conducted in the following four stages. (i) collection of data, (ii) classification of data, (iii) relative probability analysis, and (iv) modified PM10 group classification. The main results of this study are as follows. When the frequency analysis of the traditional method was conducted, 3,721 accidents occurred at a PM10 concentration of 32 μg/m3. However, as a result of the relative probability analysis presented in this study, it was confirmed that the relative accident probability increased as the PM10 concentration increased. In addition, the current PM10 concentration is presented by the WHO in six groups from a health perspective. However, in this study, the newly proposed PM10 group was classified into three groups from the perspective of the probability of construction accidents. The group proposed in this study is not from a health perspective but a group for managing construction site accidents. The contribution of this study was to confirm that PM10 also affects accidents occurring at construction sites, and the impact of PM10 on accidents was quantitatively analyzed through the relative probability analysis presented in this study.

Music therapy modulates mothers’ perception of their preterm infants

Premature birth imposes considerable challenges on the preterm infant, but also challenges the mother, who may not yet be prepared for motherhood and encounter psychological stress during the post-partum period. This secondary analysis of a prospective randomized controlled trial (RCT) aimed to investigate how mothers perceive their preterm infants. We surveyed 33 mothers of preterm infants born before 32 weeks of gestation, who were participating in an RCT on music therapy. We employed the neonatal perception inventory (NPI), an instrument designed to assess the mother’s perception and expectations regarding her infant immediately after birth. Infants were randomly assigned to either standard care (control group) or standard care plus music therapy (intervention group). Eighteen mothers from the intervention group participated in the survey (mean age 34.1 ± 4.6 years) and 15 mothers from the control group (mean age 29.6 ± 4.2 years). At the time of the infant’s hospital discharge, mothers rated their expectations of how they felt a baby should behave (NPI I) and how they perceived their own infant (NPI II). The NPI score difference was calculated by subtracting the NPI II from the NPI I. Mean NPI I scores were comparable between both groups, but NPI II scores in the intervention group were better [18.0, 95% confidence interval (CI) 16.6–19.4] than in the control group (19.1, 95% CI 18.0–20.3). The relative probability of mothers rating their own baby as better than average was 1.94 (95% CI 1.00–3.79) for mothers whose infants received music therapy. These findings suggest that music therapy in the neonatal intensive care unit can positively influence mothers’ perception of their hospitalized preterm infant.

Retrospective evaluation of real-time estimates of global COVID-19 transmission trends and mortality forecasts.

Since 8th March 2020 up to the time of writing, we have been producing near real-time weekly estimates of SARS-CoV-2 transmissibility and forecasts of deaths due to COVID-19 for all countries with evidence of sustained transmission, shared online. We also developed a novel heuristic to combine weekly estimates of transmissibility to produce forecasts over a 4-week horizon. Here we present a retrospective evaluation of the forecasts produced between 8th March to 29th November 2020 for 81 countries. We evaluated the robustness of the forecasts produced in real-time using relative error, coverage probability, and comparisons with null models. During the 39-week period covered by this study, both the short- and medium-term forecasts captured well the epidemic trajectory across different waves of COVID-19 infections with small relative errors over the forecast horizon. The model was well calibrated with 56.3% and 45.6% of the observations lying in the 50% Credible Interval in 1-week and 4-week ahead forecasts respectively. The retrospective evaluation of our models shows that simple transmission models calibrated using routine disease surveillance data can reliably capture the epidemic trajectory in multiple countries. The medium-term forecasts can be used in conjunction with the short-term forecasts of COVID-19 mortality as a useful planning tool as countries continue to relax public health measures.

The Effects of Principals’ Transformational Leadership on Teachers’ Self-Efficacy in Federal Government Educational Institutions in Karachi Region

Today's world sees leadership ideas used effectively in most organizations. The researcher wanted to investigate how school leaders' transformational methods affect teachers' self-efficacy sampled 160 secondary school teachers from Karachi's Federal Government Educational Institutions.Descriptive-correlational quantitative survey research. The Multifactor – Leadership Questionnaire by Bass and Avolio and the Teacher's Self-Efficacy Scale 1 (long form) by Megan Tschanmen-Moran and Mary Anita Woolfolk Hoy were adapted. SPSS was used for data analysis and treatment. A regression research found that all eleven institutional principle leadership styles affect teacher efforts with zero coefficients and further showed that two number variables had B-coefficient values of 0.06 (contingent reward) and 0.07 (effectiveness), with related probability not exactly at 0.05.Teachers' self-efficacy is anticipated to rise 0.06 and 0.07 points due to dependent awards and effectiveness. The study recommended that school principals maintain their leadership styles ranking and that more school advancements and reforms be enthusiastically recommended.

Multi-constructor CMSA for the maximum disjoint dominating sets problem

We propose the Multi-Constructor CMSA, a Construct, Merge, Solve and Adapt (CMSA) algorithm that employs multiple heuristic procedures, respectively solution constructors, for the Maximum Disjoint Dominating Sets Problem (MDDSP). At every iteration of the search procedure, the solution components built by the constructors are merged into a sub-instance, which is subsequently solved by an exact solver and then adapted to keep only beneficial solution components. In our CMSA the solution constructors are chosen at random according to their relative probabilities, which are adapted during the search, through a mechanism based on reinforcement learning. We test two variants of the new Multi-Constructor CMSA that employ, respectively, two and six solution constructors, on a new set of 3600 problem instances, encompassing random graphs, Watts–Strogatz networks and Barabási-Albert networks, generated through a Hammersley sampling procedure on the instance space. We compare our algorithm against six heuristics from the literature, as well as with the standard version of CMSA. Furthermore, we employ an integer linear programming (ILP) model that is able to achieve a good performance for small, sparse graphs. Overall, the experimental results show that all versions of CMSA outperform by a large margin the previous state of the art and that, among the variants of CMSA, the novel version that combines two constructors provides slightly better results than the other ones, more prominently on larger graphs.

VersKiK: Study protocol of an observational registry-based study on the current state of follow-up care and adherence to follow-up guidelines after cancer in childhood or adolescence

BackgroundThis article describes the study design of the quantitative part of the VersKiK study, The primary objectives of this study are to examine the occurrence of late effects in survivors of childhood or adolescent cancer (module 1), investigate health-related vulnerabilities and medical service utilization within this survivor group (modules 1 and 3), and assess the alignment between documented follow-up care for cardiological and audiological late effects with guideline recommendations, along with evaluating the extent of adherence among paediatric cancer survivors (module 3). MethodsThis is a non-interventional retrospective observational cohort study. It is based on stochastically linked insurance claims data from approximately 150,000 statutory insured persons with information concerning around 25,000–30,000 cancer survivors recorded in the German Childhood Cancer Register (GCCR). To explore adherence to selected follow-up guidelines, intention to treat treatment data from clinical study groups for particular diagnostic entities will be additionally included. DiscussionThe growing group of survivors after cancer in childhood and adolescence is representing a special population with an increasing demand for life-long healthcare services through relative high probability of late effects. Currently, there is a limited evidence in Germany on utilization of corresponding medical services and adherence to follow-up guidelines. With this study design, we are aiming to address these gaps and, consequently, suggest improvements to existing follow-up guidelines and follow-up care provision in Germany.

Genetic Polymorphism Analysis of 24 Y-STRs in a Han Chinese Population in Luzhou, Southwest China.

Han is the largest of China's 56 ethnic groups and the most populous ethnic group in the world. The Luzhou region is located in southwest China, at the junction of three provinces. The unique historical factors contribute to the genetic polymorphism information. Short tandem repeats (STRs) are highly polymorphic, but the polymorphism of the Y chromosomal STRs (Y-STRs) loci in the Luzhou region is still unclear. It is of great significance to provide Y-STRs genetic data for the Han population from the Luzhou areas of southwest China. A total of 910 unrelated male individuals of the Han population from the Luzhou area were recruited, and 24 Y-STRs were analyzed. The population structure and phylogenetic relationships were compared with those of another 11 related Han populations. A total of 893 different haplotypes were achieved from 910 samples, of which 877 (98.21%) haplotypes were unique. Haplotype diversity and discrimination were 0.999956 and 0.981319, respectively. The lowest genetic diversity of DYS437 is 0.4321, and the highest genetic diversity of DYS385a/b is 0.9642. Pair-to-pair genetic distance and relative probability values indicate that Luzhou Han people are close to Sichuan Han people, Guangdong Han people, and Hunan Han people, which is consistent with geographical distribution, historical influence, and economic development. The 24 Y-STR markers of the southwest Luzhou Han population were highly polymorphic, which provided us with genetic polymorphism information and enriched the population genetic database. Therefore, it is of great value to our forensic applications and population genetics research.

Cognitive social capital as a health-enabling factor for STI testing among young men in Stockholm, Sweden: A cross-sectional population-based study

ObjectiveTo assess whether different forms of cognitive social capital increased the relative probability of testing for sexually transmitted infections (STIs) among young men living in Stockholm, Sweden. MethodsA population-based cross-sectional study was conducted in 2017 with men aged 20–29 years living in Stockholm County, Sweden (n = 523). The main outcome was STI testing patterns (never tested, tested only within a12-monthperiod, tested only beyond a12-monthperiod, repeatedly tested). The main exposure were two forms of cognitive social capital: social support (having received help, having someone to share inner feelings with) and institutionalized trust (in school, healthcare, media). Data were analyzed using weighted multivariable multinomial logistic regression to obtain adjusted weighted relative probability ratio (aRPR). ResultsAfter adjusting for confounding factors, receiving help (aRPR: 5.2, 95% CI: 1.7–16.2) and having someone to share inner feelings with (aRPR: 3.1, 95% CI: 1.2–7.7) increased the relative probabilities of young men testing for STIs, but only for those testing beyond a 12-month period. Trust in media increased the relative probability of STI testing for those testing only within a 12-month period (aRPR: 2.6, 95% CI: 1.1–6.1) and for those testing repeatedly (aRPR: 3.6, 95% CI: 1.5–8.8). ConclusionYoung men in Stockholm County exhibit distinct STI testing patterns. Social support and trust in media were factors that increased the probability of being tested for STIs, with this effect varying according to the young men's STI testing pattern. Further studies are required to explore how trust in media might promote STI testing in this population.

Absence of the interthalamic adhesion (ITA) as a neuroanatomical association or risk factor for neuropsychiatric disorders: A systemic review and meta-analysis.

This study aimed to provide an up-to-date account of the frequency of "the absence of interthalamic adhesion (AITA) as a risk factor or association" in healthy subjects and neuropsychiatric patients. Owing to the increased interest in the contribution of ITA to neurological function in previous literature, a meta-analysis of its frequency and sex dependency is required. This study aimed to study whether the AITA is associated with neuropsychiatric disorders. This study is a meta-analysis and systemic review. Literature searches were conducted in PubMed, Web of Science, and Google Scholar using the keywords "interthalamic adhesion," "massa intermedia," "adhesio interthalamica," and "adhesion" along with the Boolean operators (OR, AND, and NOT). Three reviewers independently assessed the abstracts and full texts for validation based on the inclusion criteria. The meta-analysis was performed using Microsoft Excel 2019 for descriptive studies and RevMan 5.2 for comparative studies. The incidence of absent ITA was 15.3% in healthy subjects and 28.76% in neuropsychiatric subjects. The relative probability of AITA was 2.30 [95% confidence interval (CI), 1.96-2.70] in neuropsychiatric illness. Healthy men were 1.91 times more likely, and men with neuropsychiatric disorders were 1.82 times more likely to have absent ITA than women. In this study, a consistent association of AITA with psychiatric disorders was observed, rendering the condition to be treated as an associated risk factor affecting the function of the habenula nuclear complex via the stria medullaris thalami. A cohort or longitudinal study is needed to compare the incidence of psychiatric disorders in individuals with or without ITA and to calculate the attributed risk.

Measuring the ratio of true‐positive to false‐positive judgements made by child and family social workers in England: A case vignette study

AbstractSocial workers routinely make judgements and decisions as part of their everyday practice. The nature and quality of these can have a significant and long‐lasting impact on the children and families concerned. In this paper, we present an analysis of more than 20 000 judgements (n = 21 193) made by social workers (n = 586) in relation to case vignettes, based on a series of anonymized referrals (n = 12) to social services in England. We do so to ascertain how accurately the social workers were able to predict subsequent actions, events and outcomes, and to calculate the ratio of true positives to false positives at various decision thresholds. We find that the social workers' predictions were more accurate than chance in relation to all but one of the referrals, albeit at the cost of a high rate of false positive errors. We consider these findings in relation to what appears to be a general lowering of the threshold for child protection interventions in England in recent years and in relation to who suffers the injustice of false positive errors in child and family social work.

Multiscale influences on Elk (Cervus canadensis) calving site selection across a fragmented Appalachian landscape

Abstract Due to the vulnerability of neonatal ungulates, selection of a birth site can have important implications for offspring survival and thus fitness of the mother. We studied parturition site selection in cow Elk in southeastern Kentucky, United States, using a use–availability framework to evaluate the effects of landscape variables sampled at multiple spatial grains on the relative probability of use of parturition sites. We identified 81 Elk parturition sites during May–Aug 2020–2022 and fit several candidate resource selection function models using a sample of 24,314 random locations to characterize habitat availability. Using an information-theoretic approach to rank candidate models, we identified two top-performing models (cumulative ωi = 0.97), which indicated that at fine spatial grains (~10- and 30-m pixels) parturient cow Elk selected for intermediate canopy cover and lower terrain ruggedness compared to available locations. At coarse grains (250–1,000-m buffers/neighborhoods), Elk selected against vegetation greenness/biomass, for higher topographic positions, for closer proximity to major roads, and with higher solar radiation potential. We also found evidence that Elk responded positively to forest/open edge densities at coarse grains, demonstrating that calving habitat throughout the Kentucky Elk Restoration Zone is associated with heterogeneous landscapes resulting from surface mine reclamation. As a result, habitat management actions should aim to increase patchy, early successional shrub cover on gentle topography.

First estimate of distribution, abundance, and risk of encounter with aquaculture vessels for the rare Chilean dolphin in the entire Northern Chilean Patagonia

Abstract Assessing distribution and abundance patterns for rare species is challenging yet imperative, considering the extant, potentially hazardous, anthropogenic activities. In particular, the poorly studied Chilean dolphin (Cephalorhynchus eutropia) exhibits an extremely patchy distribution and low densities, co‐occurring with the intensive aquaculture industry in Southern Chile, among other anthropogenic activities. The distribution and abundance patterns of Chilean dolphins were assessed in the entire Northern Chilean Patagonia. A hierarchical species distribution model was fitted to data from line transect surveys using distance sampling techniques and environmental variables derived from topographic features and oceanographic models. A second version of this model used a joint‐likelihood approach to incorporate presence–pseudoabsence data for improving parameter estimation. Spatial predictions arising from these models were used to evaluate the relative probability of a dolphin encountering vessels from the local, predominantly aquaculture fleet. The results show that using a joint‐likelihood approach drastically reduced uncertainty in the parameters controlling the effect of covariates and in the total abundance estimates. This model estimated an overall low abundance (median 2,225.8; 95% CI 1,340–3,867) for this species in the region, and indicates their preference for shallow, sheltered bays and inner channels, near river mouths, where low salinity is expected. The highest probabilities of dolphin–vessel interactions were found on the eastern coast of Chiloe Big Island, coinciding with the largest number of aquaculture concessions in the area. Considering that the overall population of the Chilean dolphin is expected to be in the low thousands, that suitable habitat for the species is highly restricted, and that the species is facing increasing anthropogenic impacts, with some areas undergoing or planning major expansions in development, the results provided here should be considered in management plans for extant marine protected areas, and in the evaluation of current International Union for Conservation of Nature (IUCN) and national conservation categories for the species.

Response strategies for coping with imperfect items of a joint replenishment model with the adaptive bare-bone differential evolution

In joint replenishment problem with random number of imperfect items (IJRP), it is a great challenge for managers to correctly ascertain the number of imperfect items and take the right response strategy to make rectifications simultaneously. In this paper, the effectiveness of four common response strategies, i.e., scrap, all-unit quantity discount, rework & repair, and buy replacements for coping with imperfect items are investigated based on IJRP for the first time, respectively. Considering the NP-hard nature of the classical JRP and its extensions, as well as enhancing the explorable performance in crossing scale-levels of IJRP models and exploitable performance in diversifying the solution population of bare-bones differential evolutionary (BBDE), a meta-heuristic algorithm named as the adaptive BBDE (ABBDE) is designed by introducing an problem scale related adaptive recombination probability and a generalized opposition-based learning (OBL). Through numerical experiments, it has been found that (1) The adaptive improvements of ABBDE have been verified through obtaining the lower best-found total cost (TC), the lowest mean value, and the smallest standard error comparing to that of genetic evolution algorithm (GA), particle swarm optimization (PSO), differential evolution (DE), bare-bones PSO (BBPSO), BBDE. (2) Parameter sensitivity analyses indicate that the scale of yearly demand, lead-time, and significance of uncertainty have significant impacts on system cost, whilst the parameters pertinent to specific response strategy are main factors causing system cost disturbance. (3) Management insights and limitations on adoption of a right response strategy and the practical usage of ABBDE are obtained.

Composition and Age of Sources of the Lower–Middle Cambrian (?) Terrigenous Rocks from The Ernichny Formation in the Argun Massif, Eastern Part of the Central Asian Fold Belt

The paper presents the results of the mineralogical and geochemical studies of sandstones and siltstones of the Ernichny formation of the Argun series in the Argun continental massif, and the results of U–Pb (LA‑ICP-MS) dating for the detrital zircons from these rocks. It is established that the youngest detrital zircons from sandstone of the Ernichny Formation have age of 549–570 Ma. A maximum on the relative probability curve of zircon age corresponds to 566 Ma. These data determine the lower age limit of their accumulation on the border of the Ediacaran and Paleozoic age. According to the results of U–Pb dating of detrital zircon, the majority of detrital zircons from sandstones of Ernichny Formation are characterized by Neo- and Paleoproterozoic ages. The sources of zircons were Neo- and Paleoproterozoic igneous and metamorphic rocks that were widely developed within the Argun continental massif. In turn, the geochemical features of the terrigenous rocks of the Ernichny Formation, together with the presence of the poorly sorted and rounded clastic material in the studied samples, as well as the presence of interlayers of gravelstones, enabled us to establish that they were formed in a subduction-related setting.

Fire From Volcanic Activity: Quantifying the threat from an understudied hazard

Natural hazards can trigger fires that increase the area and severity of impacts beyond that caused by the initiating hazard. For some physical processes, such as earthquake, fires are a well appreciated and studied cascading hazard. However, fire from volcanic activity (FFVA) is a highly dangerous and largely understudied hazard arising from volcanic activity. To demonstrate the potential destructiveness of this hazard, we develop a FFVA ignition probability model underpinned by a widely applicable fault tree, which identifies the mechanisms that can lead to fire ignition from volcanic activity. By assigning values to each node of the fault tree, our model can be used to consider the relative probabilities associated with different fire ignition mechanisms. We couple this ignition probability model with a fire spread model to evaluate hazardous areas and associated impacts caused by FFVA. To demonstrate the applicability of our model, we use an eruption scenario for volcanic ballistic projectiles in the Auckland Volcanic Field (Aotearoa New Zealand). This case study demonstrates the potential for FFVA to compound and greatly increase the impacts caused by other volcanic hazards. We found that fire ignition and spread could increase the damaged area and monetary losses associated with the initiating hazard alone by more than six and five times, respectively. We suggest that more study is needed to better understand, evaluate, and plan for FFVA.

Employment, income, and skill alignment of humanitarian migrants in the Australian labour market: Metropolitan and regional contexts, 2000–2016

AbstractHumanitarian migration to Australia has reached new levels, accompanied by unprecedented complexity and diversity. Little is known about labour market integration for these newcomers, nor about how well their skills match those required for or relevant to their employment. Here we analyse how labour force engagement and skill alignment are influenced by migration status, including migration scheme, region of birthplace, applicant status, year of arrival, citizenship, and internal migration after settlement, and metropolitan versus regional geographic location of settlement. In particular, we focus on employed humanitarian visa holders who arrived between 2000 and 2016. Using the 2016 Australian Census and Migrants Integrated Dataset (ACMID) for quantitative analysis, our modelling established that they were not as likely to be in the labour force as skilled visa holders. Similarly, humanitarian visa holders who were employed were less likely to be in jobs that matched their skills and more likely to have lower income levels. Moreover, there were significant differences in skill alignment between those settling in metropolitan and in regional areas. The relative probability of being over‐skilled was correlated with migration scheme, origin, duration since arrival, internal movement in the year preceding the census, proficiency in spoken English, family status, and gender. Labour market outcomes varied by visa subtype and by metropolitan versus regional settlement. We conclude that the design of migration policy requires further important consideration, both to improve the outlook for this vulnerable population and to address chronic skill shortages in Australia.

Understanding Capacity Fade in Organic Redox-Flow Batteries by Combining Spectroscopy with Statistical Inference Techniques

Aqueous-soluble organic and organometallic redox-active molecules show considerable promise as redox-flow battery (RFB) reactants because their costs at scale are projected to be low. However, most aqueous organic RFB undergo rapid degradation resulting in high rates of capacity fade. Considerable research has been devoted towards discovering chemically stable charge carriers for RFBs. However, the decomposition mechanisms of underperforming chemistries during flow cell cycling are often poorly understood, and in some instances, competing or incompatible hypotheses about the relationship between reactant decay and capacity fade have often been proposed.In this talk, we will demonstrate that combining spectroscopic and statistical inference techniques can be used to shed light on relationship between RFB reactant degradation and capacity fade. Specifically, we employ in operando ultraviolet-visible spectrophotometry along with Bayesian inference, Bayesian model selection, and multivariate curve regression in order to quantify the relative probabilities of different decay mechanisms given the data at hand, and to estimate rate constants for specific reactions within the most probable decay scheme. In principle, rate constants thus obtained can be fed into a zero-dimensional electrochemical flow cell model, recently developed by our group, that can simulate capacity fade given a reactant decay mechanism, associated rates, and the cycling protocol. This work has the potential to shed light on the relationship between capacity fade and reactant decay in various organic RFB chemistries, and to enable prediction of the lifetimes of commercial-scale RFBs.

Effects of vitamins A, C, and D and zinc on urinary tract infections

Urinary tract infection (UTI) is responsible for a significant portion of the overall expenses of health care as well as mortality rates globally. We searched through the available research to evaluate whether micronutrient supplements affect the frequency and intensity of UTI in children Papers that investigated the effects of vitamins D and C, zinc, and multiple micronutrient supplementations (MMS) on the incidence and severity of UTI in pediatric patients were pooled together. A random effects model was used to conduct a meta-analysis of data. Vitamin D supplementation reduced the risk of UTI and shortened the duration of symptoms in children. If a clinical diagnosis or laboratory investigation was used to confirm UTI, the relative probability of UTI with vitamin D was remote from the null than using the self-report. If vitamin C was administrated, the frequency of UTI was reduced, and the period of clinical manifestations was cut to half. It was not possible to determine the impact of using zinc supplements. According to the findings of the current review, taking micronutrient supplements such as zinc, vitamins C and D, and multiple micronutrient supplementation could assist in preventing UTI and lessen its clinical outcome in pediatric patients. More research is required to establish the effect of individual or combination of micronutrients on the treatment outcomes of UTI.