Treaty Regulations Research Articles

Topical Trends in Outer Space Cooperation/Competition and Perspectives on Space Law

Introduction. Immanent in all history of space activities cooperation and/or competition are currently subject to significant changes. The most meaningful by impact on activity, its forms, subject content and other features, as well as on relevant international legal and national legal framework including perspectives on their development, are the two emerging international partnerships: China and Russia, primarily on the International Lunar Research Station, as well as with other cooperating states; and the United States with partners on the Artemis Program.Materials and methods. Materials – selected by criterion of fundamental impact on the ‘space law’ development examples of international legal and national legal acts underpinning one of the alternative competing international partnerships on the exploration of the Moon and deep space. Methodology includes analysis, synthesis, analogy, as well as combination of comparative law with systematic methods, and modelling with forecasting.Results. It is justified that: 1) it is reasonable to consider the combination of relevant current factors, trends, and processes (including political, economic, and technological) as the components of the branch-specific coordinate system; 2) timely identification of factors with significant impact on the industry development significantly reduces, or absolutely offsets the negative impact of transformational potential of cooperation/competition in outer space on the efficiency of the industry-related forecasting; 3) factors of fundamental impact on the development of the “space law” system are found in the international legal and national legal approaches behind the two alternative international partnerships; 4) the necessity to determine common basis for diverging legal (and other branch-specific) approaches is grounded on economic feasibility; 5) The conditions/criteria of determination of factors of fundamental impact on the system of ‘space law’ are developed; 6) The feasibility of consideration of the combination of challenging issues of space law as the components of the branch specific legal coordinate system is confirmed; 7) It is revealed that meeting priority issues leads to an updated actualization of other unsettled issues of diverse-level within the system of ‘space law’; It is justified that: 8) under actual trends actualization of branch-specific legal issues and their regulation is less dependent on relevant state’s technological potential and more on inclusion in global economic projects and political processes; 9) consideration of matches and differences under specific criteria between international legal and national legal approaches behind the two alternative international partnerships would bring forecasting on perspectives on ‘space law’ closer to real development.Discussion and conclusion. It is reasonable to consider as conceptual foundations for branch-specific risk management the creation of conditions (primarily of economic, technological and strategic character): for transformation of ‘common denominator’ of international legal and national legal approaches of the two international partnerships to the willingness of competing states to harmonize their positions on additional multilateral treaty regulation of issues subject to international space law; as well as for that competition leads to ‘balancing’ of commitment to international obligations, and inclusive development of diverse elements of the ‘space law’ system.

Bumetanide to treat autism spectrum disorders: are complex administrative regulations fit to treat heterogeneous disorders?

Introduction: Extensive experimental observations suggest that the regulation of ion fluxes and, notably, chloride are impacted in autism spectrum disorders (ASD) and other neurodevelopmental disorders. The specific NKCC1 cotransporter inhibitor Bumetanide has been shown to attenuate electrophysiological and behavioral features of ASD in experimental models. Both pilot and phase 2 double-blind randomized independent trials have validated these effects with thousands of children treated successfully. Both brain imaging and eye tracking observations also validate these observations. However, final large phase 3 trials failed, with no significant differences between placebo and treated children. Methods: Here, I discuss the possible reasons for these failures and discuss the exclusive reliance on complex patent cooperation Treaty (PCT) regulations. Indeed, available data suggest that bumetanide responders could be identified by relying notably on EEG measures, suggesting that biological sub-populations of patients might benefit from the treatment. Results: These observations raise important debates on whether treating only a % of children with ASD is acceptable. Discussion: It is likely that in many disorders, the heterogeneity of the pathological event precludes a single general treatment for all, suggesting that trials centered on selective populations of responders might be essential for large clinical trials to succeed.

Irreversibility in nuclear arms control and disarmament law?

Abstract While irreversibility of nuclear arms control and disarmament measures can be supported by compliance with applicable legal norms, the existing treaty regulation has serious gaps: pertinent treaties are not universally applicable; limitations on missiles as important carriers of nuclear warheads have been abrogated; the strategic doctrines of nuclear weapons powers are not fully transparent, and while the latter may strengthen the effectiveness of nuclear deterrence, it also raises questions as to compliance with fundamental obligations to refrain from a threat or use of force and to settle international disputes by peaceful means. There are certain principles of general international law that can and should be used in international cooperation to overcome nuclear crisis situations and strengthen international security: fundamental norms regarding the non-proliferation of nuclear weapons and nuclear disarmament under strict and effective international control have an erga omnes character and are accepted and recognized by the international community of States as a whole. Furthermore, general rules of international responsibility are fully applicable in the law of nuclear arms control and disarmament. It is in this sense that irreversibility in nuclear arms control and disarmament is served by legal principles and rules, which require States to comply with existing obligations and to cooperate for the maintenance of peace and security.

Legal Consequences of Dual and Multiple Nationality: Practice of International Legal Regulation

Introduction. The article dwells on the international legal cooperation on resolution of the consequences of dual and multiple nationality concerning extradition of bi- and polypatrids, resolution of investment disputes with their participation and provision of diplomatic protection. Theoretical Basis. Methods. The theoretical basis of the present study was based on doctrinal and legal sources, as well as legal precedents in the field of extradition of persons with dual and multiple nationality, resolution of investment disputes, and diplomatic protection. Formal-legal, comparative-legal, historical, and predictive methods were used in the research. Results. Dual and multiple nationality appear more and more widespread phenomena which is caused by the tendencies of modern interstate communication. In the absence of effective international legal regulation, in particular treaty regulation, a large number of disputes arises in connection with the legal status of bi- and polypatrids, among which the most urgent are those in the field of extradition, resolution of investment disputes and provision of diplomatic protection. The well-established approach in the area of bi- and polipatrizm implies the application of the principle of “effective nationality” in cases involving such persons. Discussion and Conclusion. The admissibility and conditions for application of effective nationality principle are frequently not stipulated in the international treaties (on extradition, on protection of investments, on dual nationality), therefore it seems advisable to supplement this kind of treaties with appropriate provisions on the procedure of effective nationality principle application.

IMPLEMENTATION OF SOFT LAW RELATING TO OUTER SPACE INTO DOMESTIC LAW

Space law is clearly oriented towards creation of soft law instruments and their subsequent implementation directly into national law. However, it is not an ideal method for regulating the peaceful use of outer space. At least a few problematic issues should be noted. Firstly, the lack of scrutiny by parliaments with regard to soft law standards accepted by States. Secondly, the multiplicity of soft law documents on the same subject matter – especially in the case of space debris (IADC, UN, ISO or ESA), which may not be fully identical. Thirdly, developments in space technology mean that existing soft law standards may nevertheless be outdated in practice. Fourthly, the creation of new soft law is not always a quick process. However, implementation of international soft law relating to outer space into domestic law ensures that international norms are binding under national law. It thus strives to guarantee both the development and the effectiveness of international space law, despite the absence of new treaty regulations.

Drivers of tax avoidance by MNEs in the developing countries under the digital economy: a modified-TISM approach

PurposeThe present research identifies a total of nine factors influencing tax avoidance under the international taxation regime of the developing countries and establishes a hierarchical relationship through modeling of the identified factors using modified-total interpretive structural modeling (M-TISM).Design/methodology/approachDue to “scale without mass” properties of the digital economy, businesses reduce their physical presence in the countries of economic activities. Aided with digital features, multinational enterprises (MNEs) avoid, abolish, or adopt flexible tax burden in the developing nations through by-passing the permanent establishment condition for company taxes or the income characterization prerequisite for royalty taxation. The present research endeavors to identify the drivers of tax avoidance in the developing countries, especially exacerbated due to digital technologies (economy). In addition, the authors also examine the hierarchical relation between the extracted drivers of tax avoidance.FindingsThis research presents a considerable driving force of elements like historical foundation of tax-treaties, dominance of the developed countries, influence of trade bodies in policy matters and finally information and communications technologies (ICTs).Originality/valueIdentified elements drive the actors like professional enablers, tax havens, international organizations, and intangible assets in the form of intellectual properties (IPs) which act upon tax arbitrage situations both under the domestic and treaty regulations, finally culminating into profit shifting, tax manipulations or avoidance.

INTERNATIONAL POLICY OF CONTRACTUAL REGULATION OF THE PREVENTION OF THE USE OF NUCLEAR ROCKET WEAPONS

The article examines the political prerequisites, the history of the formation and features of the implementation of agreements on the production, use, and non-proliferation of nuclear missile weapons and their significance for international security policy. The main areas of research were: 1) the study of the main directions of the international policy of contractual regulation of preventing the use of nuclear missile weapons; 2) a discussion of scientists on the vectors of development of contractual and legal regulation of the studied social relations among domestic and foreign scientists.
 In the course of the study, methods in political science and legal sciences were used, in particular, the formal-dogmatic method provided an opportunity to analyze this problem from the point of view of the existing provisions of international treaties and the obligations of the participating countries to prevent the proliferation and especially the use of nuclear missile weapons, system-structural. the method provided an opportunity to analyze the role and importance of the United Nations in the formation of an international contractual framework in the process of implementing international security policy in the field of nuclear missile weapons.
 The use of these and other methods made it possible to distinguish two main directions of the international policy of treaty regulation of preventing the use of nuclear missile weapons: regulation of the production and use of nuclear weapons, as well as regulation of public relations to counter nuclear terrorism. The central place in the study of these areas is given to the analysis of the Treaty on the Non- Proliferation of Nuclear Weapons dated July 1, 1968. The article formulates the main problematic points of the provisions of this Treaty and substantiates the directions for the development of the contractual framework in the process of implementing international security policy aimed at preventing the use and proliferation of nuclear missiles. weapons

Systemic Changes in the Politicization of the International Trade Relations and the Decline of the Multilateral Trading System

AbstractThis Article contributes to the discussion about the development of international trade regulation of state interventionism by situating the tensions that exist about the future design of subsidies and state enterprises treaty regulation in the broader context of current systemic challenges to the multilateral trading system. While recent studies have explored the issues of subsidies and state-owned enterprises (SOEs) as one of the most significant in impact among the contemporary challenges to the WTO, there is certainly scope to discuss further such a problem from the broader point of view of the crisis of the multilateral trading system, its systemic challenges and the concomitant increasing politicization of international trade relations. To this end, this Article analyzes the interactions between the lasting decline of the WTO, growing political interferences with international trade flows and the prospects of reforming multilateral trade rules to address its systemic challenges and manage/mitigate newly central problems of the 21st century such as the Covid-19 Pandemic, climate change and the greening of economic production and international trade. The Article argues that existing WTO rules are not adequate to address these challenges and problems. It concludes that, like in the GATT era, it is only the spirit of pragmatism that may provide chances to find alternatives to growing frustration with negotiating inaction and, hence, to reform the system. However, the question remains whether it is possible to find an approach to imagine, remodel and craft multilateral rules that are sensitive to different economic, political, and social choices and able to rebalance the position of all members, large and small, rich and poor.

On the role of the Collective Security Treaty Organization (CSTO) and ensuring security and support for Armenia as its signatory during the ongoing armed conflict with Azerbaijan

The article describes the conflict between the Republic of Armenia and the Republic of Azerbaijan, two Caucasian states with the so-called the region of Nagorno-Karabakh, which is part of Azerbaijan, inhabited and ruled for many years by Armenians. In addition to a more detailed approximation of the background of the conflict and the current role of international organizations in its resolution, the article discusses the circumstances of the creation and history of the Collective Security Treaty Organization (CSTO), which was established, among other things, to prevent and resolve conflicts among its signatories, including Armenia and Azerbaijan. The article makes a legal classification of Azerbaijan’s aggression against Armenia as a violation of the OBUZ treaty regulations and presents the legal consequences of this. It also contains a negative assessment of the current role of CSTO in settling the conflict between Armenia and Azerbaijan and a negative assessment of the Treaty’s real capacity to fulfill its functions, especially in the light of the current international situation and the current political situation in Armenia.

Legal Tools in International Environmental Law

Abstract Environmental law concepts are expressed in conventions, international binding laws, state practice and soft law commitments. They may be applicable to all foreign community members. These are widely recognized and even approved in the practice of the state. A special feature of international environmental law is that many environmental issues are governed by non–binding soft–law instruments that allow faster responses to international environmental issues. Governments tend to resist legally binding treaty regulation for different reasons but are much more likely to adopt a written action plan or resolution, at least voicing a political will to address an issue. The numerous constitutional standards of several countries must be followed when negotiating international agreements: for example, the way the national parliament must approve and enforce a treaty. The paper investigates the regulation system of international environmental law.

Treaty-Based Regulation and Evidence-Extradition Agreements as Critical Tools in the Fight against International Criminal Wrongdoing

Abstract Draft Article 7 of the UN Draft Convention regarding Crimes Against Humanity provides the terra firma for States to establish and exercise a range of jurisdictional bases, including universal jurisdiction, to be reinforced by State-to-State agreements regarding evidence-extradition for the benefit of downstream truth and justice seeking projects. Legal analysis demonstrates there persists an insistence on treaty regulation and clearly particularised laws at local and international levels to successfully pursue international criminal accountability. Draft Article 7 will give credence to universal jurisdiction, complement the International Criminal Court’s workings and counter its temporal limitations, and negate politically-motivated invocation of the doctrine. A case study involving Australian extradition proceedings highlights how evidence can be obtained efficiently on the basis of a pre-existing bilateral agreement between culturally distinct States. Formal arrangements regarding evidence-exchange will espouse a greater willingness by States to cooperate across borders and will strengthen universality by taking some of the guess-work out of its exercise.

Celowość kodyfikacji zbrodni przeciwko ludzkości przez Komisję Prawa Międzynarodowego ONZ

Tekst podejmuje analizę przyjętego w 2019 roku przez Komisję Prawa Między-narodowego projektu artykułów dotyczących zapobiegania i karania zbrodni przeciwko ludzkości, a także rozważa rolę Komisji w zakresie kodyfikacji norm międzynarodowego prawa karnego. W przeciwieństwie do zbrodni ludobójstwa i zbrodni wojennych zbrodnie przeciwko ludzkości nie zostały skodyfikowane pod koniec lat czterdziestych ubiegłego stulecia. Brak odrębnej regulacji jest problemem pomimo przyjęcia w 1998 roku statutu Międzynarodowego Trybunału Karnego. Zasadne jest zatem rozważenie potrzeby ujęcia zbrodni przeciwko ludzkości w odrębnej konwencji. Tematyka ta była obecna już w trakcie wcześniejszych prac Komisji. Pomimo rozczłonkowanej regulacji, obejmującej oddzielnie szczegółowe refleksy zbrodni przeciwko ludzkości, jak apartheid, tortury czy wymuszone zaginięcia, można przyjąć, że rdzeń definicji zbrodni przeciwko ludzkości jest dobrze zakotwiczony w międzynarodowym prawie zwyczajowym, nawet jeśli brakuje zgody co do szczegółowych kwestii. Podejmowane w ramach KPM rozważania równie dobrze mogą przysłużyć się pracom nad stworzeniem bardziej ogólnej konwencji poświęconej zbrodniom międzynarodowym.Analiza projektu artykułów przyjętych w 2019 roku potwierdza zasadniczy brak konfliktów z zobowiązaniami państw wynikającymi z aktów ustanawiających trybunały międzynarodowe, zarówno stały MTK, jak i trybunały hybrydowe o mieszanej, międzynarodowo-krajowej jurysdykcji i składzie. Zawarta w art. 2 definicja zbrodni przeciwko ludzkości powtarza analogiczną treść ujętą w art. 7 statutu rzymskiego. Prace Komisji zdają się dopełniać prace nad częścią materialną między-narodowego prawa karnego. Projekt artykułów przyczynia się też do implementacji zasady kom-plementarności wynikającej ze statutu rzymskiego. Centralnym zamysłem kodyfikacji było przede wszystkim podbudowanie prawodawstwa wewnętrznego i odnośnej działalności sądów krajowych oraz ustanowienie ram współpracy w zakresie ekstradycji oraz pomocy prawnej. Nieistnienie normy traktatowej nie jest bezwzględną przeszkodą dla pociągnięcia do odpowiedzialności na gruncie prawa międzynarodowego. Podstawy do tego może przecież dostarczać mię-dzynarodowe prawo zwyczajowe. Oczywiście związana z nim niewystarczająca precyzja wywołuje wiele problemów, przede wszystkim ze względu na zasadę legalizmu ścigania karnego.W opracowaniu odniesiono się także do negatywnego wymiaru kodyfikacji. Wybór metody traktatowej bywa niekiedy uznawany za otwarcie drogi do kwestionowania ustaleń dokonanych w konwencji, a przez to osiągnięcie zupełnie odwrotnego od zamierzonego skutku. Ale nawet pozo-stawienie kodyfikacji jako niewiążącego instrumentu ma znaczenie do ustalenia rozumienia prawa międzynarodowego na podobieństwo kodyfikacji traktatowej. Niezależnie od ostatecznej formy działalności KPM formułowanie i usystematyzowanie norm w wersji pisemnej jest przedsięwzięciem, które zapewnia postęp w prawie. Przez wzmocnienie jego pewności i okazję do wyjaśnienia i rozwijania istniejących już norm, ale też wykrystalizowanie kodyfikowanych reguł w jedną szczegółową formułę może być przeszkodą dla przyszłego rozwoju prawa i jego responsywności względem potrzeb społeczności międzynarodowej.

Щодо особливостей формування міжнародно-правових звичаїв

The article is devoted to the peculiarities of the formation of international legal customs in modern international law. The growing role of contractual relations has not been able to transform customary law into exclusively contractual law. The existing system of international law could not be imagined without international custom for several reasons: first, various branches and institutions in modern international law partially or even completely consist of customary norms, and secondly, in those areas where treaty regulation is impossible for various reasons, more and more new norms of customary law continue to arise. There are many opinions on the issue of creating customary norms of international law in international legal Science. The main question is whether these norms are formed through the interaction of the will of states or whether their appearance is not due to the participation of the will. In its historical development, custom as a source of international law has long been the most important procedure for forming international legal norms. This was due to the fact that the interstate system has never had a legislative body that would adopt such legal norms. For this reason, many international legal norms were created on the basis of the Customs and practices of states, which is why they had the character of customary legal norms. The main approach to the formation of an international legal custom is studied. The main components of international custom are considered and their exhaustive characteristics are given. The role of international custom for modern international law is clarified, as well as the indication of the need for further development of this issue in the domestic legal field for its effective use in international relations. Theoretical foundations of substantiation of nature of international custom are determined.

World Health Organization’s dispute settlement in the light of the COVID-19 pandemic: problems and perspectives

In the light of Coronavirus disease pandemic, the question of state responsibility in global health has become actual as never before. Rarely mentioned in the scientific literature, but at the same time, an important problem is the lack of an appropriate dispute settlement body which is competent to consider cases of violation of the World Health Organization’s instructions. The goal of the article is to research different bodies which are potentially competent to resolve disputes regarding violations in the scope of healthcare and to determine the most appropriate one in the light of responsibility of states over the COVID-19 pandemic. The paper analyzes the possibility of resolving a dispute regarding the new pandemic in the International Court of Justice, through arbitration, through negotiations, within an advisory body, and through the World Health Assembly. The article also considers the prospects of other organs of the World Health Organization to perform judicial functions. The paper relies on the analysis of treaty regulations regarding functioning of presented bodies, as well as on enforcement practice of these bodies. Additionally, the authors take into account an attitude of members of the World Health Organization to named bodies. The article shows the advantages and disadvantages of each dispute settlement mechanism. It also develops ways of reforming named bodies to expand their competence to hold states responsible for violations during outbreaks of infectious diseases. The paper concludes that the only body, which is currently able to assign the responsibility of states, is the main organ of the World Health Organization – the World Health Assembly. The absence of an effective way of holding states responsible for violations leads to systematic breaches of their obligations. Today responses of the World Health Organization have become a subject of significant criticism. Furthermore, the World Health Organization’s authority in the international community has been greatly shaken. Thus, effective dispute settlement in the field can solve the burning issue of seeking fairness within violations in the area of global health and also improve the effectiveness of the World Health Organization as a whole.

Some challenges of treaty regulation of international relations in the field of environmental protection

International agreements and treaties in the field of environmental protection concluded in the 19th — first half of the 20th century, were, as a rule, the result of forced compromises, they were intended to solve urgent problems that had appeared or, at least, drew attention to limited areas (for example, the threat to a certain species, pollution of a marine area). In such cases, a convention was adopted to protect an endangered species or to limit emissions into the sea. As a result of this fragmented approach to environmental protection, an impressive but very heterogeneous system of conventions has emerged. Understanding of the unity of ecosystems implemented in the development of principles enshrined in the Stockholm Declaration of 1972 and the Rio Declaration of 1992 took place largely due to the rapid progress of science and technology. As a result, there has been a transition from “spontaneous” formation of international environmental standards to their consolidation around special principles of international environmental law. Also, a notable feature of many international treaties in the field of environmental protection — their “framework” character — is further analyzed. The adoption of framework agreements leads to the formation of complex sets of conventional documents consisting of several different, but in a certain way related to each other agreements. Considering the question of the effectiveness of such a legal instrument as a framework agreement, the author concludes that the origins of the problem of insufficient effectiveness of agreements in the field of environmental protection lie in the foundations of the existing economic system.

Some Remarks on the Relationship between the Jus ad Bellum Regulations under the UN Charter and Customary International Law – Why Does It Matter so Much?

One of the key issues for conveying the modern normative structure of jus ad bellum, i.e. the international law norms governing the use of force, is the mutual relations of the treaty regulation under the United Nations Charter (the UN Charter) regime and the relevant customary law. Contrary to as it may seem prima facie, this relationship remains highly ambiguous. Obviously, it is strictly and inextricably linked with all the dilemmas and challenges of jus ad bellum regulation under the UN Charter regime in all its ambiguity. Thus, addressing the character of this relationship firstly demands referring to the mentioned dilemmas and challenges. Keywords: jus ad bellum, UN Charter, customary international law

'No‐deal’ Brexit would knock 2% off GDP by end‐2020

▀ If the two sides fail to finalise a withdrawal agreement and the UK leaves the EU in disorderly fashion in March 2019, it would cause a significant slowdown in the UK economy. Trade would be subject to additional frictions and we would expect to see a substantial sterling depreciation. The impact could be mitigated by looser monetary and fiscal policy, but we would still expect the level of GDP at the end of 2020 to be just over 2% lower than our baseline forecast. ▀ If negotiations break down in late‐2018, the UK would only have time to re‐establish the most critical of the hundreds of international trade and regulatory treaties that it is currently party to via its EU membership. So from March there would be a substantial increase in non‐tariff barriers, as well as tariffs being levied on UK‐EU trade. ▀ We would expect financial markets to respond negatively to a ‘no‐deal’ scenario, with both sterling and, to a lesser extent, the euro depreciating against the dollar, while equity prices and gilt yields would also be lower than in our baseline forecast. We predict that sterling would depreciate by 10% on a trade‐weighted basis by Q2 2019. This would mitigate some of the damage to exports from additional trade frictions. But, combined with the impact of imposing tariffs on imports from the EU, it would push UK inflation above 4% in mid‐2019, severely squeezing households. ▀ We would expect the Bank of England to look through the temporary spike in inflation and cut Bank Rate back to 0.25%. We also assume that the government would divert the funds it had earmarked for the ‘divorce bill’ into higher government consumption and to tolerate the higher borrowing caused by weaker economic growth. ▀ Looser fiscal and monetary policy should prevent a deeper downturn, but our scenario still sees the level of GDP 2.1% below the baseline (which assumes a deal and a transitional period) at end‐2020 and 2.7% lower by 2023. Its close trade links with the UK and heavy reliance on imported goods means the short‐term impact on Ireland would be significant, but the impact on the larger Eurozone economies is smaller.

К вопросу об индивидуально-договорном регулировании трудовых отношений: сущность, значение и пределы реализации

К вопросу об индивидуально-договорном регулировании трудовых отношений: сущность, значение и пределы реализации

Therapies Out of Reach: Anticancer Drugs and Global Trade Regimes

Medical policy analysts and oncologists have cautioned against the high price of anticancer drugs. They argue that the current drug development model that relies on patents and short-term shareholder value is proving unsustainable, since the cost of the new generation of drugs puts many of them out of reach for the average consumer. The high price of cancer drugs is especially troubling in the context of middle- and low-income countries, where the burden of cancer carries disproportionate impact. To analyse the pricing of anticancer drugs, we examined legal controversies, regulatory treaties and documents, as well as the history of pricing data in India. We also conducted interviews with policy consultants and surveyed financial data filings of major global and Indian pharmaceutical corporations. Our research revealed that global trade agreements have become key barriers to lowering anticancer drug prices. This article argues that in the shadow of the World Trade Organization (WTO) and with Trans-Pacific Partnership (TPP) imminent, serious policy changes are necessary to ensure the survival of generic production in the market for anticancer drugs.

О методологии права региональной интеграции

General issues of methodology are considered in the article in the frames of international integration concept. The accent is put on the interaction of national and integration systems. The attention is paid to different variations of interaction between the subjects of regional integration and consequently the necessity to percept the methodology in multifaceted format is analyzed. In particular the authors propose not to limit regional integration to standard mechanisms of international cooperation but provide for combination of treaty regulation and method of subordination. This tendency is well founded and its effective realization depends upon the mechanism of implementation. The attention is paid to the analysis of the regime of integration interaction of some regions. In particlar, the analysis of the experience of the European Union let the authors conclude that while integrating there is a gradual transition from traditional interstate method of regulation to the methods of integration, which are characterised by different level of rigidity, prescriptiveness and based upon different mechanisms of balancing of supranational and sovereign in integration community. The experience of Asia in use of special methodology in integration is synthesized.