Regulation Theory Research Articles

Semiglobal Suboptimal Output Regulation for Heterogeneous Multi-Agent Systems With Input Saturation via Adaptive Dynamic Programming.

This article considers the semiglobal cooperative suboptimal output regulation problem of heterogeneous multi-agent systems with unknown agent dynamics in the presence of input saturation. To solve the problem, we develop distributed suboptimal control strategies from two perspectives, namely, model-based and data-driven. For the model-based case, we design a suboptimal control strategy by using the low-gain technique and output regulation theory. Moreover, when the agents' dynamics are unknown, we design a data-driven algorithm to solve the problem. We show that proposed control strategies ensure each agent's output gradually follows the reference signal and achieves interference suppression while guaranteeing closed-loop stability. The theoretical results are illustrated by a numerical simulation example.

The Regulation Role of the Gut-Islets Axis in Diabetes.

The gut-islets axis is an important endocrine signaling axis that regulates the function of islets by modulating the gut micro-environment and its endocrine metabolism. The discovery of intestinal hormones, such as GLP-1 and GIP, has established a preliminary link between the gut and the islet, paving the way for the development of GLP-1 receptor agonists based on the regulation theory of the gut-islets axis for diabetes treatment. This discovery has created a new paradigm for diabetes management and rapidly made the regulation theory of the gut-islets axis a focal point of research attention. Recent years, with in-depth study on gut microbiota and the discovery of intestinal-derived extracellular vesicles, the concept of gut endocrine and the regulation theory of the gut-islets axis have been further expanded and updated, offering tremendous research opportunities. The gut-islets axis refers to the complex interplay between the gut and the islet, which plays a crucial role in regulating glucose homeostasis and maintaining metabolic health. The axis involves various components, including gut microbiota, intestinal hormones, amino acids and ACE2, which contribute to the communication and coordination between the gut and the islet.

How and Why Do Economic Operators Comply With EU Law? Analysis of Firm‐Level Responses to the EU Timber Regulation in Germany

AbstractThe European Union (EU) Timber Regulation (EUTR) formally requires EU operators to conduct due diligence along their supply chains to prevent illegally sourced timber products from entering the European market. Little is known about the regulatory behaviour and motivations of operators to comply with this regulation. We explore the regulatory behaviour of companies by applying a synthesis of behavioural theories of regulatory compliance and transnational market regulation. Informed by qualitative and quantitative mixed methods, this study finds that EUTR compliance is influenced by operators' regulative, economic, normative and cultural‐cognitive motivations. The empirical analyses reveal that larger, publicly exposed companies are driven to comply through social pressure and the deterrence effect of sanctions and control. Operators' perceptions of the costs and benefits do not explain compliance behaviour in a significant, quantitative way. The Internal values to abide by the law are found to be a stronger motivator than economic cost–benefit calculations.

Emotion Regulation and Psychological Dependence on Pain Medication among Hospital Outpatients with Chronic Spinal Pain: The Influence of Rumination about Pain and Alexithymia

Objective : To examine the extent to which pain acceptance, pain catastrophising and alexithymia moderate associations between pain intensity and psychological pain medication dependence. Methods : Participants (106 hospital outpatients with chronic spinal pain) completed the Leeds Dependence Questionnaire (LDQ) to measure psychological dependence on pain medication, and the Chronic Pain Acceptance Questionnaire-8 (CPAQ-8), the Pain Catastrophising Scale (PCS) and the Toronto Alexithymia Scale-20 (TAS-20), plus the Depression, Anxiety and Stress Scale-21 (DASS-21). Results : Multiple linear regression showed that degree of psychological dependence (measured dimensionally across the range of LDQ scores) was associated with TAS subscale difficulty identifying feelings (DIF) (β = 0.249, p = <0.002) and PCS subscale rumination (β = 0.193, p = 0.030), independently of pain intensity and risk behaviors for medication misuse. The effect of pain intensity was moderated by rumination, with pain intensity more strongly associated with dependence when rumination was high (interaction β = 0.192, p = 0.004). Logistic regression showed that the effect of pain intensity on severe dependence (measured categorically as LDQ score ≥ 20) was moderated by alexithymia, so that severe dependence was independently associated with the combination of intense pain and high alexithymia (interaction odds ratio = 7.26, 95% CIs = 1.63–32.42, p = 0.009). Conclusions : Rumination and alexithymia moderated the associations between pain intensity and psychological pain medication dependence, consistent with emotion regulation theory. This raises the possibility that specifically targeting rumination about pain and symptoms of alexithymia could potentially improve the effectiveness of psychological interventions for chronic pain and help people to avoid or reduce their psychological dependence on pain medication.

Kalman state estimator for aircraft structural load alleviation using eigenpair assignment

Process of finding the “best estimate” from noisy signals amounts to “filtering out” the noise. Many methods exist to filter the unwanted noise. A tried and tested method is to use a Kalman Filter which not only cleans up the signals but can also be used to provide signal estimates, for use in reduced order feedback control. Typically, Kalman filter gains are computed using the Linear Quadratic Regulator theory. Reduced order feedback control has been applied in aircraft control problems. One such application area is in synthetic load alleviation, structural loads that arise due to gusts and or control surface deflections. Aircraft structural load alleviation necessitates the use of robust feedback control. The controllers are required to provide load alleviation in cases where the feedback signals are contaminated with noise or missing due to sensor failures. In this paper a method of computing the Kalman gains for the purposes of reduced order feedback is presented, which completely specifies the error dynamics of the estimator in terms of its eigenvalues and associated eigenvectors. The state estimator synthesized using the proposed approach has excellent noise rejection properties and shown to be robust and can be successfully used in reduced order state feedback control, specifically in Aircraft Structural Load Alleviation control schemes. The proposed scheme demonstrates reduction in structural loads.

Alexithymia and peer victimisation: interconnected pathways to adolescent non-suicidal self-injury.

The prevalence of non-suicidal self-injury (NSSI) among adolescents underscores the importance of understanding the complex factors that drive this behaviour. Framed within broader constructs of emotional regulation theories, alexithymia and peer victimisation are thought to interact to influence NSSI behaviours. This research addresses whether alexithymia and peer victimisation serve as risk factors for NSSI and, if so, how these factors interact with each other. This quantitative study analysed data from 605 adolescents, using a range of validated self-report measures including the Toronto Alexithymia Scale. Statistical analyses including one-way analysis of variance, multiple regression and structural equation modelling were employed to scrutinise the relationships among the variables. Alexithymia and peer victimisation significantly predicted NSSI behaviours. Specifically, the 'difficulty in identifying feelings' subscale of alexithymia emerged as a noteworthy predictor of NSSI (P < 0.001). Peer victimisation mediated the relationship between alexithymia and NSSI, explaining approximately 24.50% of alexithymia's total effect on NSSI. In addition, age was a significant predictor of NSSI, but gender and education years were not (P > 0.05). These relationships were found to be invariant across genders. This study enriches our understanding of the interplay between alexithymia, peer victimisation and NSSI, particularly within the Chinese context. Its findings have significant implications for a rethinking of alexithymia's theoretical construct and interventions targeting emotional literacy and peer dynamics among adolescents. Future research could benefit from a longitudinal design to establish causality.

Neferine inhibits the progression of diabetic nephropathy by modulating the miR-17-5p/nuclear factor E2-related factor 2 axis.

To investigate the effect of Neferine (Nef) on diabetic nephropathy (DN) and to explore the mechanism of Nef in DN based on miRNA regulation theory. A DN mouse model was constructed and treated with Nef. Serum creatinine (Crea), blood urea (UREA) and urinary albumin were measured in mice by kits, and renal histopathological changes and fibrosis were observed by hematoxylin-eosin staining and Masson staining. Renal tissue superoxide dismutase (SOD), malondialdehyde (MDA) and glutathione peroxidase (GSH-Px) activities were measured by enzyme-linked immunosorbent assay (ELISA). Western blotting was used to detect the expression of nuclear factor E2-related factor 2 (Nrf2)/ heme oxygenase 1 (HO-1) signaling pathway-related proteins in kidney tissues. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was used to detect the expression of miR-17-5p in kidney tissues. Subsequently, a DN in vitro model was constructed by high glucose culture of human mesangial cells (HMCs), cells were transfected with miR-17-5p mimic and/or treated with Nef, and we used qRT-PCR to detect cellular miR-17 expression, flow cytometry to detect apoptosis, ELISAs to detect cellular SOD, MDA, and GSH-Px activities, Western blots to detect Nrf2/HO-1 signaling pathway-related protein expression, and dual luciferase reporter gene assays to verify the targeting relationship between Nrf2 and miR-17-5p. Administration of Nef significantly reduced the levels of blood glucose, Crea, and UREA and the expression of miR-17-5p, improved renal histopathology and fibrosis, significantly reduced MDA levels, elevated SOD and GSH-Px activities, and activated Nrf2 expression in kidney tissues from mice with DN. Nrf2 is a post-transcriptional target of miR-17-5p. In HMCs transfected with miR-17-5p mimics, the mRNA and protein levels of Nrf2 were significantly suppressed. Furthermore, miR-17-5p overexpression and Nef intervention resulted in a significant increase in high glucose-induced apoptosis and MDA levels in HMCs and a significant decrease in the protein expression of HO-1 and Nrf2. Collectively, these results indicate that Nef has an ameliorative effect on DN, and the mechanism may be through the miR-17-5p/Nrf2 pathway.

Longitudinal Examination of the Relationship Between Virtual Companionship and Social Anxiety: Emotional Expression as a Mediator and Mindfulness as a Moderator.

As the interweaving of human interaction and Artificial Intelligence (AI) intensifies, understanding the psychological impact, especially regarding social anxiety, of engaging with AI-driven virtual companionship becomes crucial. While a substantial body of research on social anxiety has concentrated on interactions between individuals, both online and offline, there is a noticeable deficit in explorations concerning how human-computer interactions influence social anxiety. This study offers a comprehensive, longitudinal examination of this underinvestigated relationship, intricately dissecting the roles of emotional expression and mindfulness within the context of AI-based interactions. We use social support theory and emotion regulation theory as our theoretical foundation. Data were collected from 618 undergraduate students in Eastern China over two intervals (May 15, 2023 and September 15, 2023). We utilized SPSS 26.0 to conduct descriptive statistics, while AMOS 25.0 facilitated multi-group confirmatory factor analysis (CFA) and the cross-lagged panel modeling. Our findings indicate that as the frequency of virtual companionship use increases, there's a decline in online social anxiety but a rise in offline social anxiety. Emotional expression emerges as a significant mediator, with heightened emotional expression leading to reduced social anxiety in both contexts. Mindfulness serves as a potent moderator, suggesting its protective role against the potential pitfalls of frequent virtual interactions. This research not only deepens our theoretical understanding of the dynamics between virtual interactions and social anxiety but also serves as a cornerstone for future endeavors aimed at optimizing AI and devising therapeutic interventions tailored for the digital generation.

Data-Based Collaborative Learning for Multiagent Systems Under Distributed Denial-of-Service Attacks

This paper employs a reinforcement learning (RL) technique to investigate the distributed output tracking control of heterogeneous multiagent systems (MASs) under multiple denial-of-service (DoS) attacks. Different from existing results where the dynamic of the leader is known for partial or all agents, the leader’s system matrix is completely unknown for each follower in this paper. To learn the leader system matrix, a data-based learning mechanism is first proposed using the idea of the data-driven method. Then, under the data-based learning mechanism, a resilient predictor subject to multiple DoS attacks is exploited to provide the estimation of the leader’s state for each agent, where adversaries attack different communication links independently. Moreover, a resilient dynamic output feedback controller is proposed to solve the output tracking control problem based on the output regulation theory. To consider the transient responses of agents, a RL-based dynamic output feedback controller is developed to realize the optimal output tracking control by solving discounted algebraic Riccati equations (AREs) in both offline and online ways. Theoretical analysis shows that the secure output tracking control of MASs can be achieved under the proposed data-based resilient learning control algorithm. Finally, a numerical example is provided to verify the effectiveness of theoretical analysis.

Working with a Mask: How and When Workplace Mask Wearing Decreases Employee Emotional Exhaustion

AbstractDespite the salutary effects of mask wearing broadly recognized during the COVID-19 pandemic, little is known about the consequences of wearing masks in the workplace. The current research raises the question of whether and how mask wearing may impact employees' emotional well-being at work. Drawing on emotion regulation theory (e.g., Gross, 1998, 2015), we propose that mask wearing enables employees to adopt more authentic emotional displays, which in turn decreases emotional exhaustion. Furthermore, guided by the social interaction model of emotion regulation (Coté, 2005), we further posit that for employees whose work requires more frequent face-to-face interaction, the positive impact of mask wearing on emotional exhaustion becomes more significant. Across a pilot study and a three-wave field survey, we find support for this hypothesized model. Implications of these findings for future theorizing and research on mask wearing are discussed.

Conceptual Utility Model for the Management of Stress and Psychological Wellbeing, CMMSPW™ in a university environment: theoretical basis, structure and functionality.

This article describes and introduces the Conceptual Utility Model for the Management of Stress and Psychological Wellbeing, CMMSPW™ Its purpose is to assess, evaluate and treat stress and psychological wellbeing. First, the theoretical assumptions of the model are presented. This model is an application of the 3P Model, Theory of Internal vs. External Behavioral Regulation and the Model of Competency for the Management of Stress and Psychological Wellbeing. Second, the conceptual structure of the model is presented. This model allows the structural and functional determination of the variables and predictive, mediating and final factors for stress and psychological wellbeing. Third, the functional structure is presented. For predictive factors, the internal and external self-regulation theoretical model allows us to assess levels of internal and external regulation of the individual and their context, as well as other personal and contextual factors involved in self-regulation. For mediating factors, the model of competence for the management of stress and wellbeing allows us to analyze conceptual (concept and principles), mediating (skills and metaskills) and attitudinal (attitudes, values and habits) variables. Finally, in relation to factors that condition outcomes, we can determine levels of response to stress and psychological wellbeing. Finally, limitations and conclusions are presented. The model also allows us to determine predictive relationships between those three types of variables and is functionally transferable to other contexts, including contexts proper to the psychology of education, clinical practice and healthcare, and psychosocial, organizational and technological contexts.

Breaking boredom: Interrupting the residual effect of state boredom on future productivity.

Boredom is an emotion that constantly fluctuates in employees of all ages and occupations. Here, we draw on functional theories of boredom and theories of emotion regulation to develop an episodic model of how boredom shapes employee attention and productivity over time. We argue that employees often suppress boredom at work to "power through" boring tasks and objectives, resulting in residual bouts of mind-wandering-and thus productivity deficits-during future performance episodes. However, following boredom on an initial task, the commencement of a subsequent task that employees perceive to be meaningful creates an attentional pull that breaks the link between boredom and future mind-wandering, preventing the effects of boredom from spilling over to inhibit future productivity. Study 1 draws on archival experience sampling data to test our hypotheses and examine whether boredom exhibits reciprocal relationships with mind-wandering and productivity over time. Study 2 uses an experimental design to determine whether boredom and task meaningfulness interact to exert a causal effect on future mind-wandering. Study 3 uses a time-separated single-day design to replicate Studies 1 and 2 and examine our contention that employees often suppress boredom at work which, rather than preventing the effects of boredom, puts them "on hold" until a later point in time. Our findings provide insight into how to mitigate the far-reaching effects of boredom at work; they also advance episodic accounts of emotions, attention, and performance in organizations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Effect of acute stress on working memory in pilots: Investigating the modulatory role of memory load.

Many practitioners, such as pilots, frequently face working memory (WM) demands under acute stress environments, while the effect of acute stress on WM has not been conclusively studied because it is moderated by a variety of factors. The current study investigated how acute stress affects pilots' WM under different memory load conditions. There are 42 pilots conducting the experiments, consisting of 21 stress group participants experiencing the Trier Social Stress Test (TSST) and 21 control group participants experiencing the controlled TSST (C-TSST). Subsequently, both groups performed N-back tasks under three memory load conditions (0-back, 1-back, and 2-back). State Anxiety Inventory (S-AI), heart rate (HR), and salivary cortisol concentrations (SCC) were collected to analyze acute stress induction. The results revealed that (1) the TSST could effectively induce acute stress with higher S-AI, HR, and SCC; (2) higher memory load reduces WM accuracy (ACC) and delays response times (RT); (3) acute stress increases WM ACC under moderate load conditions (1-back task). These results suggest that acute stress may not necessarily impair WM and even improve WM performance under certain memory load conditions. Potential mechanisms of acute stress effects on WM and alternative explanations for the modulatory role of memory load consistent with the emotion and motivation regulation theory are discussed. These findings not only provide insight into the field of acute stress and WM but are also beneficial for pilot training and the development of stress management strategies.

Fast and Curious: ‘The Swiss Development Puzzle’. The Institutional Roots of the Success of Industrialization

ABSTRACT The article investigates the institutional roots of the Swiss organized capitalism that contributed to the success of its industrialization and its subsequent economic growth during the second industrial revolution (1880–1913). Recent literature underlines the link between public and private actors and shows that the second industrial revolution in Switzerland owed its success to state-led organized capitalism. If the majority of studies analysed in detail one or more components of the Swiss organized capitalism, to our knowledge, there are no works seeking to explain the (institutional) construction of this organized capitalism by mobilizing a large number of factors in a single theoretical frame of reference. Using the Regulation Theory approach, this article sheds light on the institutional construction of the Swiss organized capitalism. We show that it rested on original institutional arrangements driven by the necessity to survive on external markets. We therefore demonstrate that these arrangements also enabled Switzerland to successfully deal with the production of essential public goods supporting both industrialization and national social bonds required to promote political unity.

Arousal dysregulation and executive dysfunction in attention deficit hyperactivity disorder (ADHD).

Attention deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental condition, that continues to have an elusive etiological background. A number of extant models and theories have historically intended to explain the many factors contributing to ADHD behaviors. One of the most accepted hypotheses has been the executive dysfunction theory associating reduction in executive control to abnormalities in structure and operational dysfunction of dopaminergic signaling networks. Nevertheless, executive functions are not always impaired in ADHD, and the literature describes other symptoms commonly reported suggesting individuals with ADHD would appear to suffer from a more general deficit. Another existing line of research, that has gained much attention recently, establishes that ADHD would have dysregulated states of brain arousal that would account for its commonly observed cognitive deficits and behavioral symptoms, described as the state regulation theory, which has now included measures of autonomic function. This article describes some important aspects that compose and challenge these two most influential theoretical constructs, executive dysfunction and state-regulation, based on their empirical evidence, implying the need to reevaluate the norms used to classify individuals and establish ADHD diagnosis. Large number of controversial results continue to exist within the study of ADHD biological and/or performance markers, possibly due to such heterogeneity and variability within the same diagnosis. The need to resolve these issues and establish newly revised diagnostic criteria for ADHD is critical, as therapeutic success depends on having accurately identified underlying neurophysiological factors in order to appropriately address them in treatment.

Temperament Affected Visuospatial Orienting on Discrimination Tasks.

In the Posner cueing paradigm, the early attentional capture and subsequent inhibition of return (IOR) of attention to the same location, although they are microscale phenomena measured in milliseconds, seem to encapsulate the interaction between two fundamental dimensions of behavior - engaging in and sustaining activity versus withdrawing from and inhibiting activity. In the field of differential psychology, the dynamics of reciprocal relations between these behavioral dimensions have been thought to be determined by central nervous system properties that constitute an individual's temperament. Yet the research on any differential effects of temperament on visuospatial orienting is rather sparse and has produced ambiguous results. Here, we used saccadic responses to measure whether individual differences in reactivity as a temperamental trait might affect orienting of visuospatial attention on discrimination cueing tasks. Our results suggested that, in individuals with lower reactivity, attentional capture took place at a short stimulus onset asynchrony (SOA), producing a facilitatory cueing effect, which was not the case in those who were higher in reactivity. We explain and discuss these results with the Regulative Theory of Temperament.

AChE activity self-breathing control mechanisms regulated by H2Sn and GSH: Persulfidation and glutathionylation on sulfhydryl after disulfide bonds cleavage

Hydrogen sulfide (H2S), or dihydrogen sulfane (H2Sn), acts as a signal molecule through the beneficial mechanism of persulfidation, known as the post-translational transformation of cysteine residues to persulfides. We previously reported that Glutathione (GSH) could regulate enzyme activity through S-desulfurization or glutathionylation of residues to generate protein-SG or protein-SSG, releasing H2S. However, little is known about the mechanisms by which H2Sn and GSH affect the disulfide bonds. In this study, we provide direct evidences that H2Sn and GSH modify the sulfhydryl group on Cys272, which forms disulfide bonds in acetylcholinesterase (AChE), to generate Cys-SSH and Cys-SSG, respectively. Glutathionylation of disulfide is a two-step reaction based on nucleophilic substitution, in which the first CS bond is broken, then the SS bond is broken to release H2S. H2Sn and GSH controlled self-breathing motion in enzyme catalysis by disconnecting specific disulfide bonds and modifying cysteine residues, thereby regulating AChE activity. Here, we elucidated H2Sn and GSH mechanisms on disulfide in the AChE system and proposed a self-breathing control theory induced by H2Sn and GSH. These theoretical findings shed light on the biological functions of H2Sn and GSH on sulfhydryl and disulfide bonds and enrich the theory of enzyme activity regulation.

New Insights into HIV Life Cycle, Th1/Th2 Shift during HIV Infection and Preferential Virus Infection of Th2 Cells: Implications of Early HIV Treatment Initiation and Care.

The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1) and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a result of studies in mice, whereby T-helper cell subsets were found to direct different immune response pathways. Subsequently, this hypothesis was extended to human immunity, with Th1 cells mediating cellular immunity to fight intracellular pathogens, while Th2 cells mediated humoral immunity to fight extracellular pathogens. Several disease conditions were later found to tilt the balance between Th1 and Th2 immune response pathways, including HIV infection, but the exact mechanism for the shift from Th1 to Th2 cells was poorly understood. This review provides new insights into the molecular biology of HIV, wherein the HIV life cycle is discussed in detail. Insights into the possible mechanism for the Th1 to Th2 shift during HIV infection and the preferential infection of Th2 cells during the late symptomatic stage of HIV disease are also discussed.

Regulation theory and the reform of vocational education in New Zealand

ABSTRACT This article critically evaluates the Reform of Vocational Education (RoVE) reforms in New Zealand which were prompted by a financial crisis in the sector. Despite the best efforts of policy makers, faith in New Zealand’s market-led system has been in decline for many years and the RoVE takes the decline in faith in New Zealand’s market-led system a decisive step further. Drawing on the regulation theory and new localism literatures, this article argues that RoVE has emerged as the latest flanking mechanism, or palliative activity, designed primarily to address legitimation deficits created by the decline in the efficacy of New Zealand’s market-led system of VE.

“It’s essential”: practicum supervisees’ emotion regulation challenges and their doctoral supervisors’ responses

ABSTRACT Novice supervisees inevitably experience intense emotional challenges during their practicum experience. Their supervisors often must help them manage their emotional reactions, suggesting the relevance of emotion regulation (ER) theory to supervision practice. Five doctoral supervisors described examples of their counseling practicum supervisees’ client-based (e.g. countertransference, trauma-related responses) and supervision-based (e.g. constructive feedback) ER challenges and how they responded. Consensual Qualitative Research (CQR) analysis revealed supervisors responded in line with process model of ER, including individualized other-focused and interpersonal emotion regulation (IER) strategies. Findings suggest further investigations could advance supervision research and practice as well as inform ER theory.