Regioselective Sulfonation Research Articles

Proton Acid‐Catalysed Transformations of Estrogen Derivatives: New Results and Some Mechanistic Aspects of the Kober Colour Reaction

AbstractThe 3‐O‐methylated estrogen derivatives 1a‐d and α‐estradiol (1e) underwent sulfuric acid‐catalysed transformations to furnish the steroids 2–6. The processes involved in the reaction sequence are regioselective sulfonation and, above all, the Wagner‐Meerwein rearrangement of the methyl group at C‐13. With the objective of obtaining further information on the course of the Kober colour reaction of estrogens, some UV/VIS and ESR spectroscopic investigations were also carried out.

ChemInform Abstract: Regioselective Sulfonation of a Secondary Hydroxyl Group of Cyclodextrins.

Abstract A new and convenient procedure has been developed for the regioselective tosylation of a C-2 hydroxyl group of cyclodextrins via cyclic tin intermediate.

Regioselective sulfonation of a secondary hydroxyl group of cyclodextrins

A new and convenient procedure has been developed for the regioselective tosylation of a C-2 hydroxyl group of cyclodextrins via cyclic tin intermediate.