Reference Point Research Articles

The Design and Development of Hands-on Activities for Digital Forensics Education

It has been widely admitted by researchers and educators that hands-on activities are a core component in digital forensics education to help students gain practical skills that are needed in real-world forensic investigations. However, it is not clear in existing works about what kinds of hands-on activities are recommended to be integrated into a digital forensics course and how to design and develop them. In our teaching practice, hands-on activities for a digital forensics course are designed in three categories: 1) activities that assist students in learning how to use common digital forensics tools; 2) activities that help students gain in-depth understanding of the basic concepts and fundamental knowledge that are presented in class lectures; 3) activities that promote students the development of mindsets and data analytical skills that are needed for a digital forensic investigator. Various formats are employed to develop these hands-on exercises in different categories. The educational objectives and student learning outcomes map well to the CAE-CD (Centers of Academic Excellence - Cyber Defense) outcomes by completing their forensic knowledge units. In this paper, we share our idea and experience to design and implement such hands-on assignments in each category for meeting specific educational objectives. Sample exercises are briefly described to explain our idea in each category. Open source tools and data sets are introduced for references. Experiences, lessons, and sample feedback from students are discussed. Our results will provide a point of reference for those who teach digital forensics courses at a college or university, or are developing a digital forensic curriculum.

Upgrading Passenger Vehicle Emission Standard Helps to Reduce China's Air Pollution Risk from Uncertainty in Electrification.

Upgrading to the CHINA 7 standard is crucial for managing air pollution from passenger vehicles in China. Meanwhile, China aims to achieve carbon neutrality by 2060, which necessitates large-scale replacement of gasoline vehicles with electric vehicles in the future. Consequently, the public might view upgrading gasoline vehicles to the CHINA 7 standard as redundant. However, the emission reduction benefits of upgrading standards in the context of uncertain electrification ambitions have not received adequate attention. Here, we show that upgrading standards will compensate for the absence of emissions reductions due to hindered electrification efforts. In the best scenario, China's CO2 emissions can be reduced to 0.047 Gt and NOx to 8.2 × 103 t in 2050. In nonextreme electrification scenarios with CHINA 7 standard, the emission intensity reduction will remain the main driver for emission reductions, outweighing the electrification contribution. In extreme electrification scenarios, upgrading standards will tackle the increased emissions from plug-in hybrid electric vehicles. Our fleet-level results advocate for early standards upgrades to enhance resilience against air pollution risks arising from uncertainties in electrification. Our evidence from China, with one of the most stringent emission standards, can provide a reference point for the world on the upgrading passenger vehicle emission standard issue.

Sustainability of European agri-food supply chain using MRP-PCI multicriteria analysis method

The need for a more sustainable agri-food system is a topic that has attracted growing interest in recent years. Several international and European policies such as Agenda 2030 and the European Green Deal have been defined with the aim of making agri-food systems more sustainable at all stages of the supply chain, from production to consumption. Particularly, the European Union concentrates several policies on it. Therefore, the assessment of the level of sustainability among the states of the European Union is a key aspect to properly address and evaluate the implementation of these policies. The objective of this paper is to measure the sustainability of the global agri-food supply chain (AFSC) of the European Union countries through the application of a multi-criteria analysis. In particular, the method used is the Multiple Reference Point Partially Compensatory Indicator, which allows the creation of composite indicators using different levels of compensation across them. A set of 50 indicators, referred to 2011 and 2019, were built and then divided into the three basic dimensions of sustainability (economic, social and environmental), aggregated into the four main AFSC sectors (agriculture, food industry, distribution, and consumption) in order to obtain an overall sustainability index. Through such an index we provided a sustainability ranking for the EU countries, while the analysis of dimensions of each sector contributed to increase the knowledge about the supply chain that can be used by decision-makers. According to the results, Italy achieved the best level of sustainability of the AFSC with a value of 48.53, followed by Sweden, Austria, Spain, France, Germany, the Czech Republic, Portugal and Slovakia. In relation to the different sectors, the biggest problems were observed in the consumption sector, where most countries did not perform well, especially for the social dimension (e.g. excess of overweight and obese persons). In contrast, the performance of the agricultural sector was good, with few exceptions, showing a fair state of sustainability.

Low speed impact simulation of explosive charge based on three-dimensional numerical manifold method

The present work addresses the challenge of evaluating the low speed impact response of polymer bonded explosive charges with three-dimensional numerical manifold method. Based on the cover-based contact theory, the contact algorithm is implemented by transforming position relationships between reference points a0 and entrance block E(A, B). Meanwhile, based on statistical micro-cracks, a Visco Scram mechanical model for the explosive charge is established. Using the classic Steven test, the influence of charge thickness, diameter, and warhead shape on the mechanical response are analyzed under low speed impact. The simulation results indicate that, increasing the thickness of the charge can effectively avoid internal damage of the explosive caused by projectile extrusion and holder confinement; Increasing the aspect ratio of the charge can alleviate the large deformation; Increasing the shape and size of the warhead can make the charge extrusion shallower, alleviating the concave shear damage of the charge. The simulation results verifies that the developed contact algorithm in this paper can effectively solve 3D impact problems, and provides guidance in the design of charge structures to some extent in the weapon system.

Motivation and Ability: Unpacking Underperforming Firms’ Risk Taking

Do firms take more or less risk in response to performance shortfalls? Although the behavioral theory of the firm (BTOF) has been a guiding framework in this area, empirical evidence remains inconclusive. Moreover, empirical work has largely failed to distinguish between firms’ motivation to take risks and their ability to do so. In this study, recognizing the distinct roles played by these two components, we specifically focus on risk-taking motivation. Drawing on March and Shapira’s shifting-focus-of-attention model, we highlight that firms’ motivation to take risks is contingent on their chosen reference points and the shifts between them. We propose that, on average, risk-taking motivation exhibits a positive monotonic relationship with performance shortfalls, a sequence involving an initial increase, subsequent leveling off, and then a renewed increase. To advance the theory of risk-taking motivation, we extend our inquiry to consider the moderating effect of concern for firm survival and subsequently explore factors influencing this concern. Furthermore, we investigate a critical implication of differentiating risk-taking motivation and ability. Because of the mismatch between motivation and ability, underperforming firms take the greatest risks when their performance is moderately below aspirations, with motivation and ability being at moderate levels, leading to an inverted U-shaped relationship between performance shortfalls and risk taking. Empirical evidence derived from experiments and archival data supports our theoretical predictions. This study contributes to the BTOF literature by demonstrating that underperforming firms’ risk-taking behavior is jointly determined by their motivation, ability, focus of attention, and concern for survival. Funding: This work was supported by the Israel Science Foundation [Grant 677/20]. Supplemental Material: The online appendices are available at https://doi.org/10.1287/orsc.2020.13953 .

On the conditions for absolute minimum fuel burn for turbofan powered, civil transport aircraft and a simple model for wave drag

Abstract In a recent series of papers, Poll and Schumann have been developing a simple model for estimating fuel burn for turbofan powered, civil transport aircraft for a given mass, Mach number and flight level and in a specified ambient temperature profile for all phases of flight. This paper focuses upon the combination of Mach number and flight level at which an aircraft cruises with the absolute minimum fuel burn. For a given aircraft type, the information necessary to determine these conditions must be specified and this poses a challenge. An initial attempt to obtain these data has been described previously by the first author. In this paper, the optimum conditions are found using a completely different approach. Starting from first principles and using established theory, the equations governing the situation where engine overall efficiency and airframe lift-to-drag ratio both have local maxima at the same flight condition are developed. This special case is termed the “design optimum” condition and, for a specified aircraft mass and a specified atmospheric temperature versus pressure profile, it gives the lowest possible fuel burn for any aircraft and engine combination. The design optimum occurs at a particular Mach number and Reynolds number, and it is a fixed characteristic of the aircraft. The analysis reveals the significance of Reynolds number variations, wave drag, including its derivatives with respect to both lift coefficient and Mach number, and the atmospheric properties. Whilst wave drag is notoriously difficult to determine accurately, it is found that solutions to the equations are not particularly sensitive to the accuracy of this quantity. Consequently, a simple, physically realistic model can give good results. An appropriate model is developed and a complete, approximate solution is obtained. Taking the International Standard Atmosphere as the design atmosphere, results are presented for the 53 aircraft types previously considered by Poll and Schumann. Relative to the design optimum conditions, when Reynolds number is constant and wave drag is zero, compressibility alone reduces L/D by about 5%, reduces lift coefficient by about 1.5% and increases drag coefficient by about 3.5%. Reynolds number variation has little effect upon L/D, but it reduces lift coefficient and drag coefficient by a further 7% and 8% respectively. The reduction in lift coefficient has a significant impact on the optimum cruise flight level. In general, an aircraft’s operating optimum will not coincide with its design optimum, but deviations are expected to be small. Therefore, using the design optimum solution as a reference point, an improved version of the operating optimum estimation method described by Poll and Schumann in previous work is developed. This allows the estimation of the conditions for absolute minimum fuel burn for an aircraft of given mass flying thorough any atmosphere. Updated coefficients for the 53 aircraft types are given.

Особенности рецепции «онегинского текста» в литературном процессе XXI в.

The present article is devoted to the study of the specifics of the “Onegin text” development in the modern literary process, which allows us to determine the nature of the reception of the classical text in the Russian poetry of recent decades. The aim of the research is to study the peculiarities of development and transformation of plots and motifs of the “Onegin text” in the literary process of modernity. The scientific novelty is determined by the fact that for the first time modern poetic revisions of A. S. Pushkin’s novel in verse “Eugene Onegin” are comprehended in the stated aspect, which allows us to expand the idea of their problem-thematic originality and compositional principles, as well as to determine the place of poetic paraphrases in the literary process of the XXI century. As a result, firstly, it is established that the emergence of a large number of the “Onegin texts” in the modern literary process is caused both by the desire to move away from the clichéd perception of the classical model and to comprehend modern reality through the prism of the genre of Pushkin’s novel in verse. Deconstructing the genre canon of Pushkin’s work, modern authors create travesty texts, various kinds of paraphrases and parodies of the classical plot, where the iconic hero becomes a marker of the contemporary era. Secondly, it was found that the authors of the 21st century create fanfics in order to draw attention to the creative personality of the creator of the text, to make it popular on the Internet. In addition, the emergence of the “Onegin texts” is due to the desire to reflect on the imperfections of the era, when the classical picture of the world is taken as a reference point.

Controllable synthesis of CeFeO3/Fe+2Fe2+3O4/C composites with improved microwave absorption performances

Magnetic-dielectric component modulation and heterogeneous interface engineering have been acknowledged as a highly potent strategy for the effective development of lightweight and broad-spectrum electromagnetic wave (EMW) absorbers. In this investigation, a series of carbon-based Ce/Fe-MOF derivatives were successfully synthesized via the carbonization process of Ce/Fe-MOF precursors. The EMW absorption characteristics of these derivatives were investigated by manipulating the metal ion ratio and the pyrolysis temperature. Notably, the Ce/Fe-MOF-700 composite, derived from the calcination of Ce/Fe-MOF with a molar ratio of Ce/Fe of 1:2 at 700 °C, demonstrated an impressive minimum reflection loss value of −44.6 dB at 1.38 mm. Furthermore, it exhibited an efficient absorbing bandwidth (EAB) of 6.88 GHz at a thinner coating thickness ranging from 1.38 to 1.8 mm. This remarkable ability of these materials to attenuate EMW can be ascribed to the heightened conductivity dissipation, polarization dissipation, magnetic dissipation, and enhanced impedance matching achieved by these materials. The findings of this study provide a novel point of reference for the design of lightweight and broad-spectrum EMW absorbing materials.

Просвітницька місія філософії освіти в сучасному світі

The work is dedicated to highlighting the modern educational mission of the philosophy of education in Ukraine, since education is a tool for building a civil society, and the philosophy of education is its methodological and educational reference point. The theoretical basis of the work is the function of the civilizational purpose of the philosophy of education: to become a specific methodology for the awakening of the “human in a person”, the education of an intellectual personality through education. The work defines the main educational directions in the field of philosophy of education: scientific-educational and ethical-humanistic. The scientific-educational direction is aimed at the formation of rational knowledge: the intellectual development of the individual and the increase of the intellectual potential of society. The scientific-educational direction is determined by the unions of scientists and teachers interested in the development of education and science of their country: here the philosophy of education must work with such categories-tools as knowledge, reason, common sense, thinking, understanding – and its educational mission is to develop educational paradigms that allow for the development of individual intelligence. The ethical-humanist direction involves work on the moral improvement of generations, which most actively occurs during education and upbringing (acquiring knowledge and intellectual development) and the formation of moral qualities of the individual – “what one should be in order to be a person”. The algorithm of human education is based on the main human virtues outlined by the entire world philosophy: wisdom, justice, courage, moderation. The conclusions speak of the need for new enlightenment in Ukrainian society, and the practical goal of philosophical and educational enlightenment is defined as helping modern people to become more civilized – educated and highly moral.

Collaborative strategy research of target tracking based on natural intelligence by UAV swarm

Regarding the regional area target collaborative tracking problem widely existing in intelligent scenarios, this paper built a distributed UAV swarm framework inspired by natural intelligence to heighten intricate missions’ efficiency. Also, a standoff collaboratively continuous tracking strategy was proposed based on a lateral guidance law with an improved Reference Point Guidance (RPG) and a longitudinal guidance law with an improved phase collaboration. Under an uncertain environment, this framework used an improved bat algorithm (IBA) to optimize the speed allocation of the UAV swarm’s online control strategy with information consensus estimation. Compared with a case without the designed transformation, statistically, the results demonstrate that the framework operates efficiently and robustly in phase error convergence, swarm flight distance, and fuel consumption, where a dynamic target exists.

Globale Kompetenzen und Bildung für nachhaltige Entwicklung. Eine bibliometrische Analyse zur Verortung der globalen Kompetenzen der OECD im wissenschaftlichen Diskurs

AbstractThe Programme for International Study Assessment (PISA) regularly assesses a set of interdisciplinary competences in addition to the traditional core domains. With the 2018 assessment of ‘global competences’, the OECD (2019) aims to support evidence-based decisions on the improvement of the curricula and teaching in order to prepare young people to become active and global citizens who contribute to the achievement of the Sustainable Development Goals (SDGs). In assessing this domain, the OECD is entering a field of research characterised by dynamic debates and heterogeneous research strands. The aim of this paper is to visualise the theoretical foundations on which the analytical PISA 2018 Global Competence Framework (OECD 2019) is based, allowing a transparent discussion of the different theoretical reference points. The bibliometric analyses reveal that discourses related to Education for Sustainable Development (ESD) are hardly taken into account in the analytical framework. The paper subsequently formulates impetus from the ESD research field with the aim of linking discourses in the future.

Damage assessment on an asymmetric sandwich composite made of natural materials using strain gauges

Sandwich composites have been a growing subject of interest to various industries, thus it has become essential to monitor these structures. There is a need to implement damage identification and characterization strategies. This work aims to study the reliability of the implementation of strain gauge sensors, the mechanical properties of an asymmetric sandwich composite made by a core of cork agglomerate, two fibre-reinforced epoxy skins and a natural stone on top. Initially, destructive bending tests were conducted to establish the maximum load for the specimens. This served as a crucial reference point for subsequently employing strain gauges to investigate the mechanical properties of the composite. Finally, the destructive bending tests were performed using strain gauges in order to assess the performance of strain gauges to detect damage within the composite. The study provides comprehensive insights into various mechanical properties, including bending strength, tensile, compressive, and flexural moduli, as well as the determination of the neutral line location within the material. Notably, the results from the destructive bending tests employing strain gauges demonstrated their effectiveness in detecting catastrophic events within the composite. This research contributes to the advancement of reliable structural integrity monitoring and characterization techniques for sandwich composites.

Water quality management of micro swamp wetland based on the “source-transfer-sink” theory: A case study of Momoge Swamp Wetland in Songnen Plain, China

Swamp wetlands play a pivotal role in conserving water sources, regulating river runoff, and maintaining water safety and balance. The study pioneers a new research framework in the field of pollution ecology of swamp wetlands, with a focus on the complex “source-transfer-sink” processes affecting water quality in micro swamp wetlands, an area previously under-researched. Taking the Momoge Wetland in the Songnen Plain as an example, we innovatively combined the “source-transfer-sink” theory with landscape patterns, topographic factors, and their impacts on wetland water quality. Using Partial Least Squares Structural Equation Modeling (PLS-SEM), our research quantifies and models the relationships among various environmental factors. This approach reveals how landscape patterns influence pollutant migration and water quality at a micro-scale. Our findings suggest that a 700-m buffer zone is most effective in capturing the fluctuations in water quality in arid wetlands, which is crucial for wetland management practices. We identified the main pollution sources in the Momoge Wetland, including sediment (21.60%), vegetation (24.94%), livestock and crop-related non-point sources (41.21%), and hydrodynamic factors such as water diversion (12.25%). In pollutant migration, land use emerged as the most significant factor affecting water quality (56.64%), followed by landscape patterns (25.54%). Notably, our study finds that grasslands are essential for water purification, and a uniform distribution of landscape patches significantly improves water quality. This research marks a significant stride in understanding and optimizing landscape patterns to enhance water quality in micro swamp wetlands. The insights gained are invaluable for the protection of these ecosystems and promoting their ecological value functions, providing a reference point for future wetland conservation and management strategies.

Modeling multi-scale relationships between wilderness area changes and potential drivers: Evidence from the southeast coastal area of China

An understanding of the trends and causes of wilderness change is critical in supporting wilderness conservation. However, quantitative measurement of the driving mechanisms of wilderness area changes with incorporation of spatial heterogeneity remains a challenge. An integrated wilderness mapping method was employed in this study, with Fujian Province, one of China's first Ecological Civilization Pilot Areas, serving as a case study, to identify the recent spatial distribution and the land-use change matrix of wilderness area changes in the densely populated southeast coastal regions of China. We investigated the potential drivers of changes in wilderness areas from three perspectives: anthropogenic activities and socioeconomics, natural environment, and protected areas management policies, and captured spatial variations using a Multi-Scale Geographically Weighted Regression model (MGWR). The area and quality of wilderness areas showed a decreasing trend from 2000 to 2020, with area decreasing by an average 3.63% annually and wilderness degradation being especially severe from 2010 to 2020. The loss of wilderness areas is influenced by multiple drivers, and under the influence of spatial heterogeneity, different drivers on wilderness areas have a cross-scale spatial character. Human activities and economic development are dominant in driving wilderness degradation and can exert pressure at a large scale. Protected areas may mitigate wilderness loss in the region, but wilderness near protected areas may face greater threats. Natural factors such as vegetation, precipitation and elevation have ambivalent effects, and in some area’s climate change may interact with human activities to exacerbate wilderness loss. Compared with global regression and geographically weighted regression models, MGWR produces more realistic results in modeling the relationship between wilderness area changes and potential drivers. This study provides a new perspective for wilderness research, reveals the complex mechanisms of change in wilderness areas, and provides important guidance for global wilderness conservation efforts as well as a reference point for exploring the synergistic interaction between economic development and natural conservation in the densely populated southeast coastal regions of China.

Evaluation of a school-based health education program on hepatitis B virus infection prevention practice in rural South-Western, Nigeria.

Hepatitis B virus (HBV) infection prevention is most effective early in childhood with vaccination programme. However, where this is missed, primary prevention modes of intervention become an alternative recommendation to be considered before the occurrence of risk exposure to the virus. This study sought to evaluate outcomes of a theory-based HBV infection prevention educational intervention among students from four selected secondary schools in Ogun state, Nigeria. A quasi-experimental design enrolling 256 consenting secondary school students from four schools in Ogun state randomized into three intervention schools consisting teacher-instructed (E1), peer-directed (E2) and combination of the two (E3) respectively with a control group ( C) was implemented. The theory-based educational intervention was for six weeks with follow-up period of 8 weeks. A 66-item validated instrument was used to collect data at three reference points and response items for variables in the study were transformed into weighted-aggregate scores of mean and standard deviation of HBV infection prevention practice of participants. Statistical analysis of ANOVA, paired-sample t-test and Cohen's D Effect Size (ES) was used to quantify the changes produced by the intervention on the outcome variable at 5% level of significance. At baseline, there was no significant difference (p > 0.05) in the mean HBV infection prevention practice scores between the four groups E1 (17.21 ± 3.03), E2 (15.57 ± 1.90), E3 (17.90 ± 3.10), and C (15.20 ± 2.44). However, at 14th week follow up, there was observed significant differences in mean scores of HBV infection prevention practices between all four groups E1 (23.09 ± 2.4), E2 (22.6 ± 3.6), E3 (23.82 ± 2.3), and C (15.25 ± 2.4). Paired-sample t-test conducted demonstrated significant differences between baseline and 14th week follow up for E1 (17.21 ± 3.07 and 23.18 ± 2.9; p = 0.001), E2(15.57 ± 1.90 and 23.53 ± 3.12; p = 0.001), E3(17.90 ± 3.10 and 25.1 ± 2.6; p < 0.001), but not for C (15.20 ± 2.44 and 15.25 ± 2.4; p = 0.92), with most significant impact (ES(95%CI) on HBV infection prevention practices observed for E2(3.106 95%CI: [2.66 to 3.55; p = 0.001]). Importantly, the participants in E2 showed more improvement in prevention practices than their counterparts from E1, E3, and control. Therefore, the intervention demonstrated proof-of-concept in facilitating behavior modification expected. Peer education can be utilized as a strategy to promote Hepatitis B infection prevention practices among adolescents.

Valuation of marine areas for merchant shipping: an attempt at shipping spatial rent valuation based on Polish Marine Areas

As part of the progressive process of extending spatial plans to cover an increasing number of marine areas, with the aim of objectively balancing the interests of various users of the marine area, it has become necessary to establish the value of marine areas as a yardstick or determinant of the user group for which a given marine area is of greater value. This study seeks to fill a research gap by attempting to develop a method to calculate the value of marine areas for the commercial shipping industry. This is done to make it possible in the future to prepare the ground for policy regulating the spatial rent of the sea, whose most important users are shipowners and their ships. We use the homogeneous basin of the Polish Marine Areas (PMA) in the Baltic Sea. Based on a literature review, we conclude that such a method does not exist, posing a significant challenge in the process of marine/maritime spatial planning (MSP) and maritime policy formulation. Conducting an in-depth analysis of 2020 data on ship traffic in the basin noted above, combined with a financial analysis of shipowners’ operating costs and profitability indicators, we can determine the value of marine areas both in aggregate for all shipping in the studied basin and for each of the five segments of shipping – the bulk cargo, ro-ro cargo, container, tanker, and passenger segments. In addition, through a dynamic analysis of ship traffic, it is possible to determine the value of sea area in Polish seawaters per unit of area (1 km²) at the average level and for the five specified market segments. The obtained values show that the total profits of shipowners in the Polish Marine Areas, which are at the level of more than EUR 103 million per year, and the average value of profits per 1 km² of marine area used by a ship provide future decision-makers with an objective point of reference to shape future policies for the fiscalization of public space, including the sea.

A Delphi consensus on clinical features, diagnosis and treatment of major depressive disorder patients with anhedonia amongst psychiatrists in the Asia-Pacific.

Anhedonia, a core diagnostic feature for major depressive disorder (MDD), is defined as the loss of pleasure and interest in daily activities. Its prevalence in MDD patients vary from 35 to 70%. Anhedonia in MDD negatively impacts functioning and is associated with treatment resistance and poorer prognosis for various clinical outcomes. Owing to its complexity, there remains considerable heterogeneity in the conceptualization, diagnosis and clinical management of anhedonia in MDD. This modified Delphi panel was conducted to elicit expert opinion and establish consensus on concepts relating to clinical features, diagnosis and treatment of MDD with anhedonia (MDDwA) amongst psychiatrists in the Asia-Pacific region. Seven themes were covered. A three-stage process was adopted for consensus generation (two online survey rounds, followed by a moderated consensus meeting). Statements were developed based on a literature review and input from a steering committee of six regional experts. The panel included 12 psychiatrists practicing in Australia, China, Hong Kong, Japan, South Korea and Taiwan with ≥5 years of specialist clinical experience, including assessment or management of patients with MDDwA. Overall, consensus was achieved (median ≥8) on 89/103 statements (86%). About half of the statements (55/103, 53%) achieved consensus in Round 1, and 29/36 modified statements achieved consensus in Round 2. At the moderated consensus meeting, five modified statements were discussed by the steering committee and consensus was achieved on all statements (5/5). The findings highlighted a lack of clear and practical methods in clinical practice for assessing anhedonia in MDD patients and limited physician awareness of anhedonia in Asia-Pacific. Insights from this Delphi consensus provide a reference point for psychiatrists in Asia-Pacific to optimize their strategies for personalized diagnosis and management of patients with MDDwA. Identification of distinct and clinically relevant subtypes in MDD may be valuable for guiding personalized diagnosis and management approaches, including type-specific therapies.

Comparing pronunciation challenges in South Korean preschoolers with unilateral single-sided deafness due to cochlear nerve deficiency to a norm-referenced standard.

This study aimed to compare the development of pronunciation in South Korean preschoolers with unilateral cochlear nerve deficiency (CND) to that of age-matched preschoolers with normal hearing, a topic that has not been explored previously. In a retrospective analysis, 25 preschoolers with unilateral CND who had undergone a speech evaluation battery, including a pronunciation and vocabulary test, were enrolled. Utilizing the Urimal Test of Articulation and Phonation and customized language ability tests, pronunciation and vocabulary were assessed. The subjects' speech evaluation scores were converted into age-adjusted z-scores using normal controls' data. While vocabulary performance was within normal limits, their average pronunciation z-score was -2.90, significantly lower than both the zero reference point and their vocabulary z-scores. None of the subjects scored above average in pronunciation. Thirteen patients were recommended for articulation therapy, seven were considered as potential candidates for this therapy, and the remaining five were within normal limits. There was no observed correlation between the development of pronunciation and vocabulary. Notably, some subjects' pronunciation scores did not improve, even after serial follow-up during their preschool years. Despite typical vocabulary development, preschoolers with unilateral CND exhibit significant delays in pronunciation. These findings emphasize the necessity for vigilant monitoring of their language development.

Analytical Method for Quantifying Monoterpenoids (p-Cymene and Myrcene) in Nanoemulsions Using High-Performance Liquid Chromatography.

Myrcene and cymene, aromatic monoterpenes found in plants and essential oils, possess distinctive aromatic qualities. However, their volatility and limited solubility pose challenges in precise handling and formulation. Meanwhile, nanoemulsions emerge as promising drug delivery systems, improving the bioavailability and stability of these active ingredients. This article aimed to develop an HPLC method for the quantification of two monoterpenoids, p-cymene and myrcene, in nanoemulsions. The method used a Phenomenex® Synergi™ Fusion-RP column (150 mm × 4.6 mm id, 4 μm particle size) on an HPLC system with isocratic elution. The mobile phase was composed of acetonitrile and water (60:40, v/v) and was validated in terms of specificity, linearity, accuracy, precision, robustness, and selectivity. The method provided accurate and precise results with a correlation coefficient of 0.999 and RSD values of less than 2%. The method can be used for quality control of nanoemulsions containing these monoterpenoids and as a reference for future studies on their efficacy and stability. The study demonstrates the feasibility of using HPLC for the quantification of monoterpenoids in nanoemulsions and its potential as a quality control tool for nanoemulsion-based drug delivery systems. The method's accuracy, precision, and reliability, as evidenced by high correlation coefficients and low RSD values, underscore its suitability for ensuring the consistent formulation of these monoterpenoid-containing nanoemulsions, while also serving as a reference point for future research endeavors in this field.

Flood risk transfer analysis based on the “Source-Sink” theory and its impact on ecological environment: A case study of the Poyang Lake Basin, China

Driven by climate change, the frequent occurrence of regional destructive floods poses a grave threat to socio-economic systems and ecological environments. Previous flood risk studies have disregarded risk transfer within a region, resulting in inadequate flood risk assessment and ineffective disaster prevention and mitigation outcomes. Therefore, this study introduced the “Source-Sink” theory into flood disaster field to constructing flood risk transfer model. Flood risk assessment and transfer was conducted in the Poyang Lake Basin, China, where the impacts of the initial and transfer statuses on ecosystem service values were quantified. The results showed that the flood risk in the Poyang Lake Basin was relatively low, with high spatial distribution characteristics in the central-north areas but low in the surrounding areas. High-risk zones were mainly distributed southwest of the Poyang Lake. The lower-risk zones exhibited a contiguous distribution and were surrounded by higher-risk zones. Following the completion of the flood risk transfer, high-risk zones increased significantly; but there were a few zones where the risk was transferred to other zones, thereby lowering their risks. Flood risk transfer occurs primarily in low- and medium-risk zones, with high-risk zones being the most important growth targets. The change in risk transfer was most evident in the area surrounding Poyang Lake, while that in the Upper Gan River Basin was lower and less sensitive to the transfer effect. Accounting for flood disaster risk, the ecosystem service values of the Poyang Lake Basin decreased by 8.18 %, with the most significant impacts observed in the surrounding environment and southwest Poyang Lake. After the completion of the flood risk transfer, the ecosystem service value in the Poyang Lake Basin declined by 24.66 %. This study provides a reference point for flood risk management and sustainable regional development that account for risk transfer.