Satellite monitoring of forests plays a relevant role in the agendas of tropical countries, mainly in the framework of international negotiations to implement a mechanism that ensures a reduction in global CO2 emissions from deforestation. An efficient way to approach this monitoring is to avoid duplication of efforts, generating products in a regional context that are subsequently adopted at the national level. In this effort, you should take advantage of the different data sources available by integrating geospatial tools and satellite image classification algorithms. In this research, a methodological framework was developed to generate cost-efficient national maps of forest cover and its dynamics for the countries of Central America, and its scalability and replicability was explored in the Democratic Republic of the Congo (DRC) and the State of Pará in Brazil. The maps were generated from Landsat images from the years 2000, 2012, and 2017. New geoprocessing elements have been incorporated into the digital classification procedures for satellite images, such as the automated extraction of training samples from secondary sources, the use of official national reference maps that respond to nationally adopted forest definitions, and automation of post-classification adjustments incorporating expert criteria. The applied regional approach offers advantages in terms of reducing costs and time, as well as improving the consistency and coherence of reports at different territorial levels (regional and national), reducing duplication of efforts and optimizing technical and financial resources. In Central America, the percentage of forest area decreased from 44% in 2000 to 38% in 2017. Average deforestation in the 2000–2012 period was 197,443 ha/year and that of 2012–2017 was 332,243 ha/year. Average deforestation for the complete period 2000–2017 was 264,843 ha/year. The tropical forests in both the State of Pará, Brazil, and the DRC have decreased over time.