Reducing Dentine Hypersensitivity Research Articles

Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study

Objective: The objective of this 8-week, single-center, double-blind, three-cell, randomized, clinical study was to compare the efficacy in reducing the dentin hypersensitivity of three commercially available toothpaste: Group A toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate; Group B toothpaste containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride; and Group C toothpaste containing 5% potassium nitrate and 917 ppm fluoride as sodium monofluorophosphate. Materials and Methods: One hundred and fifty subjects, who reported to the department having teeth sensitive to tactile and air blast hypersensitivity, were assigned to one of the three study groups (50/group). Subjects were then asked to brush their teeth for 1 min, twice daily, with the given toothpaste. The dentin hypersensitivity of the two selected teeth was evaluated at baseline, 2 weeks, 4 weeks, and 8 weeks. Comparison of the treatment groups was conducted using the VAS analysis. Results: All 150 subjects complied with the protocol and completed the 8-week clinical study; there were no adverse events on the soft or hard tissues of the oral cavity. Group A resulted in more improvement in the reduction of sensitivity at 2, 4, and 8 weeks compared to the other groups. Conclusions: Group A toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate significantly reduces dentin hypersensitivity and more effective than Group B and Group C toothpaste. Group A toothpaste is the latest new tool in the armament of the modern dentist.

Ways of solving the problem of dentin hypersensitivity in children after professional oral hygiene

To design an algorithm of decreasing dentin hypersensitivity in children after professional oral hygiene. Intact teeth extracted for orthodontic reasons in children and adults were involved in the pilot study. The enamel surface was cleaned by manual instruments and then polished with polishing pastes containing sodium bicarbonate, fluoride, calcium and phosphates. The results were studied with the help of a scanning electronic microscope. 60 14-15 years schoolchildren, the residents of Krasnogorsk, a town in the Moscow region, took part in the study. All of them were diagnosed dental plaque (K03.6) and underwent professional oral hygiene by manual instruments. Then the teeth were polished with polishing toothpastes. To reduce dentin hypersensitivity after these procedures the SENSODYNE Rapid Relief toothpaste was applied. The pilot study showed a destructive effect of a manual instrument on the tooth enamel especially in children. The data of the scanning electronic microscope demonstrated that the manual method with the use of polishing pastes containing sodium bicarbonate, fluoride, calcium and phosphates led to a significantly lower negative effect of this manual method on the tooth enamel both in children and adults. The application of SENSODYNE Rapid Relief by children at home after professional oral hygiene led to a decrease of dentin hypersensitivity by 65, 37%. The designed algorithm of the children's follow-up procedures after professional oral hygiene includes the application of polishing pastes containing sodium bicarbonate, fluoride, calcium, phosphates and the Sensodyne Rapid Relief toothpaste at home. This helps to minimize negative consequences of manual tooth plaque removal in case of professional oral hygiene.

Clinical Evaluation of a Dentifrice Containing Nhap for the Reduction of Dentin Hypersensitivity

Clinical Evaluation of a Dentifrice Containing Nhap for the Reduction of Dentin Hypersensitivity

Effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) on dental hypersensitivity: A randomized controlled clinical trial.

ObjectiveThis randomized controlled clinical trial aimed to evaluate the effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) in the treatment of dentin hypersensitivity (DH), and the impact of this on the health-related quality of life (HRQL).MethodsEighty teeth with DH were randomized into four groups and received three treatment sessions: PLACEBO = placebo + LASER application mimicking; CPP-ACPF = CPP-ACPF + LASER application mimicking; PBM = placebo + LASER active application; CPP-ACPF+PBM = CPP-ACPF + LASER active application. Tactile (exploratory probe) and evaporative (triple syringe) stimuli were used to measure DH and were recorded with the aid of a visual analogue scale (VAS) after the 1st, 2nd and 3rd treatment sessions and one-month follow-up. The HRQL was recorded in the DH experience questionnaire (DHEQ).ResultsThe intragroup comparison showed a significant reduction in DH (p < 0.05) with both stimuli after one-month follow-up. The intergroup comparison with the evaporative stimulus showed that CPP-ACPF+PBM significantly reduced DH when compared to the rest of treatments, after one-month follow-up. CPP-ACPF+PBM group statistically differed from the other treatment groups in the DHEQ evaluation after one-month follow-up.ConclusionAfter one-month follow-up, the association of CPP-ACPF with PBM was effective in the reduction of DH and promoted a positive impact on the HRQL of the participants of this study.

Abstracts from the 7th Congress of the World Federation for Laser in Dentistry European Division June 20–22, 2019 Parma, Italy

Abstracts from the 7th Congress of the World Federation for Laser in Dentistry European Division June 20–22, 2019 Parma, Italy

Limited Evidence Suggests That Many Types of Desensitizing Toothpaste May Reduce Dentin Hypersensitivity, but Not the Ones With Strontium or Amorphous Calcium Phosphate

Effect of desensitizing toothpastes on dentine hypersensitivity: A systematic review and meta-analysis. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. JDent (2018)75:12-21. The authors reported that this research did not receive any specific funding from the public, commercial, or not-for-profit sectors. Systematic review with meta-analysis of data.

A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste.

Dentine hypersensitivity (DH) is a common and harrowing dental condition. A novel BioMin-F technology that contains 5% fluorocalcium phosphosilicate bioactive glass has been introduced. It forms fluorapatite, which is more stable towards acid erosion. There is a lack of literature with the utility of this toothpaste in treating DH. Therefore, the authors of this randomised clinical trial have aimed to compare and evaluate the efficacy of 5% fluorocalcium phosphosilicate with an 8% arginine and calcium carbonate and placebo toothpaste. A total of 75 patients clinically diagnosed with DH were randomly divided into three groups: Group A, 5% fluorocalcium phosphosilicate; Group B, 8% arginine and calcium carbonate; and Group C, placebo. The DH was evaluated by tactile and evaporative stimuli, and a visual analogue scale (VAS) was used for evaporative stimuli at pre-baseline, baseline (15days) and post-baseline (1month). The results showed symptoms of DH were reduced in all three groups. However, Group A showed a better reduction of DH than the other two groups. The toothpaste containing 5% fluorocalcium phosphosilicate was reported to be more efficacious than the other two toothpastes in managing DH. This novel development opens up a unique opportunity in the prevention and management of DH and may also be beneficial in preventing acid erosion of the tooth surface and in the maintenance of oral hygiene by reducing the effects of plaque accumulation and gingival inflammation.

A long-term evaluation of experimental potassium oxalate concentrations on dentin hypersensitivity reduction: A triple-blind randomized clinical trial

ObjectiveThe aim of this split-mouth, triple-blind, randomized clinical trial was to evaluate the long-term clinical efficacy of experimental potassium oxalate concentration (10%) in relieving dentin hypersensitivity (DH), after a four-session application protocol. MethodsPotassium oxalate gels with different concentrations (5 and 10%) were randomly assigned to half of the 31 patients from the sample in a split-mouth design. The desensitizers were applied following a four-session protocol, one session every 48 h. The primary outcome was the assessment of pain level with the visual analog scale (VAS, 0–10), at baseline, immediately after each desensitizing session, and also after the seventh day and along 1-,3-, 6-, 9- and 12-months follow-ups. Statistical analyses were performed using Friedman repeated measures and Wilcoxon signed rank tests (α = 0.05). ResultsFor both groups, the minimum of three sessions were required for the achievement of lower DH levels. Regardless of the concentration, the desensitizing effect was maintained all the way to the end of the 6-month follow-up. The 10%-potassium oxalate group was more effective for both 9 and 12-months follow-up periods (p < 0.001). No complications and adverse effects were observed. ConclusionsWhen a four-session protocol is applied, both concentrations of potassium oxalate (5 and 10%) proved to be effective on DH reduction for up to six months. However, the higher concentration promoted better long-term results.Clinical Significance: The DH is an increasing condition in clinical practice, which affects the patient’s life quality. This study provides primary clinical evidence, suggesting that multiple application sessions and higher concentrations of potassium oxalate may result in maintenance of the desensitizing effect for more extended periods.Trial registered under number: ClinicalTrials.gov NCT03083496.

Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis.

To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration. Medline/PubMed, Cochrane Library, EMBASE and ClinicalTrials were searched for articles published between 1 January 2008 and 14 November 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was registered in PROSPERO, number CRD42019121986. Seventy-four randomised clinical trials were included in the systematic review, reporting patients from 16 to 65years old, with a clinical diagnosis of DH, that evaluate the efficacy of a desensitising product, compared to pre-treatment, used the evaporative method stimulation and the visual analogue scale. These studies evaluated 5366 patients and at least 9167 teeth. Seven follow-up periods were considered corresponding to an immediate, medium or long-time effect. Sixty-six studies were included in the quantitative synthesis. Glutaraldehyde with HEMA, glass ionomer cements and Laser present significant immediate (until 7days) DH reduction. Medium-term (until 1month) reduction was observed in stannous fluoride, glutaraldehyde with HEMA, hydroxyapatite, glass ionomer cements and Laser groups. Finally, long-term significant reduction was seen at potassium nitrate, arginine, glutaraldehyde with HEMA, hydroxyapatite, adhesive systems, glass ionomer cements and LASER. All active ingredients show efficacy in DH reduction in different follow-up times. Only in-office treatments are effective in immediate DH reduction, maintaining its efficacy over time. For long-time effects, at-home treatments can also be used. More standardised evaluation protocols should be implemented to increase the robustly of the results.

Treatment of Gingival Recession Associated with Non-Carious Cervical Lesions Using Resin Modified Glass Ionomer Cement with Connective Tissue Graft a Randomized Controlled Clinical Trial

Introduction: Gingival recession (GR) is a common aesthetic problem associated with the cervical wear of the tooth structure and dentin hypersensitivity. Recently, periodontal-restorative approaches have been proposed for the management of GR associated with non-carious cervical lesions (NCCLs), which has proven effective. The present study aimed to evaluate this method. Methods: In total, 30 subjects with isolated Millers class I GR associated with NCCL in the maxillary canines and premolars were randomly assigned to group A (CTG) and group B (R+CTG). Clinical parameters, including the probing pocket depth (PPD), relative GR (RGR), keratinized tissue width (KTW), keratinized tissue thickness (KTT), relative clinical attachment level (CAL), cervical lesion height (CLH), and dentin hypersensitivity (DH), were recorded at baseline (BL) and after one and six months. In addition, maximum root coverage (MRC) was evaluated after six months. Results: In both groups, a statistically significant reduction was observed in the PPD, RGR, and CLH after six months (P=0.001). On the other hand, a significant increase was observed in the KTW, KTT, and CAL in both groups (P=0.001). Moreover, the visual analogue pain scores indicated a significant reduction in both groups, while the reduction was considered more significant in group B (P˂0.05) compared to group A. In groups A and B, 69.24% and 61.54% of the sites showed MRC, respectively. Conclusion: According to the results, both groups achieved comparable root coverage, while the presence of restoration led to a greater reduction in dentin hypersensitivity.

A randomised controlled trial to investigate the efficacy of an oxalate strip for the management of dentine hypersensitivity pain

ObjectivesTo compare a 3.14% potassium oxalate strip and 8% arginine calcium carbonate toothpaste for the reduction of dentine hypersensitivity after 2 and 4 weeks. MethodsThis was an examiner-blind, parallel study in 80 healthy adults with dentine hypersensitivity (Schiff score >2) in >1 tooth. After acclimatisation, participants were randomised to the oxalate desensitising strip with fluoride toothpaste or the arginine desensitising toothpaste control which also contained fluoride. Products were applied under supervision of study staff after measuring baseline sensitivity, thereafter the strip or control toothpaste (fingertip application) was applied after 1 and 2 weeks, and teeth brushed twice-daily with the fluoride (test group) or the fluoridated arginine control toothpaste. Sensitivity was assessed following airblast (Schiff and VAS) and tactile stimuli (Yeaple probe) at baseline, 2 and 4 weeks. ResultsBoth groups showed significant reductions from baseline in VAS, Schiff and Yeaple sensitivity scores after 2 and 4 weeks (p < 0.0005). The oxalate group had significantly lower Schiff and higher Yeaple probe scores compared to control after both time points (p < 0.0002 and p < 0.05), but while scores favoured the oxalate group, there were no significant differences in VAS. ConclusionsThis study demonstrated application of a 3.14% potassium oxalate strip combined with toothbrushing with paste was more effective in pain management of dentine hypersensitivity than brushing with arginine toothpaste. Clinical SignificanceTreatment of sensitive teeth with the oxalate strip reduced dentine hypersensitivity after 2 and 4 weeks to a significantly greater degree than a positive control sensitivity toothpaste demonstrating that oxalate strips are an effective targeted treatment for dentine hypersensitivity sufferers.

Hydroxyapatite in Oral Biofilm Management.

Particulate hydroxyapatite, Ca 5 (PO 4 ) 3 (OH), shows a good biocompatibility and is used as a biomimetic ingredient in dental care formulations due to its similarity to human enamel. Numerous studies show its efficiency, for example, in reducing dentin hypersensitivity, and in the remineralization of enamel and dentin. In addition, oral care products with hydroxyapatite improve periodontal health under in vivo conditions. This review article summarizes data on the effects of hydroxyapatite particles in oral biofilm management. Two databases (PubMed and SciFinder) were searched for studies using specific search terms. In contrast to frequently used antibacterial agents for biofilm control, such as chlorhexidine, stannous salts, and quaternary ammonium salts, hydroxyapatite particles in oral care products lead to a reduction in bacterial attachment to enamel surfaces in situ without having pronounced antibacterial effects or showing unwanted side effects such as tooth discoloration. Furthermore, antibacterial agents might lead to dysbiosis of the oral ecology, which was recently discussed regarding pros and cons. Remarkably, the antiadherent properties of hydroxyapatite particles are comparable to those of the gold standard in the field of oral care biofilm management, chlorhexidine in situ . Although biomimetic strategies have been less well analyzed compared with commonly used antibacterial agents in oral biofilm control, hydroxyapatite particles are a promising biomimetic alternative or supplement for oral biofilm management.

Comparative Evaluation of Stannous Fluoride and Arginine Bicarbonate Desensitizer in the Reduction of Dentinal Hypersensitivity after Ultrasonic Scaling – A Randomized Controlled Trial

Comparative Evaluation of Stannous Fluoride and Arginine Bicarbonate Desensitizer in the Reduction of Dentinal Hypersensitivity after Ultrasonic Scaling – A Randomized Controlled Trial

Clinical efficacy of diode laser alone and in combination with desensitizing varnish in dentinal hypersensitivity treatment (Randomized Controlled Trial)

This study aimed to evaluate the efficacy of diode laser alone and with topical sodium fluoride varnish on reducing dentine hypersensitivity (DH) in patients with chronic periodontitis. Materials and Methods: Forty patients having stage I and Stage II periodontitis were selected according to the criteria of AAP (2017) with complaint of (DH) after routine periodontal therapy . Patients were randomly divided into two groups: group1- received NaF varnish then diode laser application at 1 W (PW) ,(CW) for 30 seconds using 320µ fiber. Group-2, treated with laser irradiation only. Each tooth received three application Dentine hypersensitivity evaluation was by tactile, air-blast, and thermal stimuli and measured using VAS scores. The patient’s response was recorded at baseline, one month and 3 month after the applicationResults : The results were statistically analyzed, significant pain reduction was showed in both groups. However , it was found that in the laser plus varnish group, tangible reduction in dentine hypersensitivity scores more than in laser alone group on the three tested stimuli at one and three months. VAS score differences between the groups were statistically significant Conclusion : It was concluded that diode laser plus NaF varnish is more effective than laser alone in reduction of patients’ dentine hypersensitivity among chronic periodontitis patients.

Effect of a stannous fluoride toothpaste on dentinal hypersensitivity: In vitro and clinical evaluation

BackgroundThe authors conducted an in vitro and a clinical study to assess the effect of a toothpaste containing stannous fluoride to occlude dentin tubules and reduce dentinal hypersensitivity. MethodsFor the in vitro study, the authors treated the surface of human dentin specimens with test or control toothpaste slurries and then evaluated them by using various spectroscopic techniques. For the clinical study, male and female participants who met the inclusion criteria brushed their teeth twice daily for 1 minute with test or control toothpaste. The authors assessed dentinal hypersensitivity by using tactile and air blast stimuli at baseline and after 4 and 8 weeks. All statistical tests of hypotheses were 2 sided, with a significance level of α set at .05. ResultsResults from in vitro studies showed that the test toothpaste effectively occluded the dentinal tubules with a deposit consisting of tin, zinc, phosphate, and silicon. The test and control toothpastes occluded the tubules 82% and 35%, respectively. Clinically, at the 4- and 8-week examinations, the test toothpaste provided statistically significant (P < .001) improvements in tactile dentinal hypersensitivity scores of 27.8% and 42.0% and in air blast hypersensitivity scores of 21.4% and 32.3%, respectively, relative to the control toothpaste. ConclusionsThe in vitro results indicate the toothpaste containing 0.454% stannous fluoride effectively coated dentin surfaces and occluded patent dentin tubules. Compared with the control toothpaste, the test toothpaste provided a significant reduction in dentinal hypersensitivity after 8 weeks of product use. Practical ImplicationsA multi-benefit option for patients with dentinal hypersensitivity.

Effect of Lasers on Dentine Hypersensitivity: Evidence From a Meta-analysis

ObjectivesThe aim of the study was to evaluate the immediate and long-term desensitizing effect of lasers in reducing dentine hypersensitivity (DH) compared with negative controls. Material and methodsSix databases were searched to identify relevant articles published up to June 8, 2018. Randomized controlled trials comparing lasers with placebo or no treatment control in adult patients who suffer from DH were included. The risk of bias was assessed according to the Cochrane guidelines, and the quality of the evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation tool. Inverse-variance random effects meta-analyses of standardized mean differences and 95% confidence intervals were performed using the RevMan 5.3 software. ResultsTwenty-two randomized controlled trials were finally included in the meta-analysis, and 21 studies of these were conducted to analyze the immediate and long-term effects. All types of lasers had better immediate and long-term desensitizing effects on DH than negative controls. The quality of evidence of the included studies showed that lasers compared with negative controls had moderate-quality immediate and long-term effects on DH. The statistical heterogeneity of these comparisons was high, for which the result of I2 ranged from 90% to 98%. ConclusionsOur results indicate that all types of lasers had a better desensitizing effect on DH than negative controls, both in immediate and long term. Furthermore, more high-quality studies with a large sample size are needed to confirm our results (PROSPERO CRD42018102260).

Dentinal Hypersensitivity Treatment Using Diode Laser 980 nm: In Vivo Study.

The discomfort of patients due to dentinal hypersensitivity (DH) is one of the main challenges that dentists face in daily practice. Difficulties in DH treatment gave rise to many protocols which are currently used. The aim of this clinical study is to evaluate the effectiveness of a new protocol on the reduction of dentinal hypersensitivity with diode laser 980 nm and the application of a graphite paste. 184 patients enrolled in the study, the degree of pain was evaluated by visual analog scale (VAS), graphite paste was applied on the exposed dentine before irradiation, the application of diode laser 980 nm with continuous mode, backward motion, tangential incidence of the beam in non-contact mode and a delivery output of 1 W. Fiber’s diameter was 320 μm and total exposure time depended on the time necessary to remove the graphite paste from the teeth. Statistical analyses were performed with Prism 5® software. Pain in post-operative significantly decreased immediately after the treatment. Mean values stayed stable until a 6-month follow-up. The application is considered to be safe with long-term effectiveness.

Comparative evaluation of neodymium-doped yttrium aluminum garnet laser with nanocrystalline hydroxyapatite dentifrices and herbal dentifrices in the treatment of dentinal hypersensitivity.

Background:The aim of this study was to compare and evaluate the efficacy of neodymium-doped yttrium aluminum garnet laser with and without herbal and nanohydroxyapatite dentifrices in management of dentinal hypersensitivity (DH).Materials and Methods:A total of 180 patients who responded to air-blast test and cold-water test using verbal rating scale (VRS) were included in this study. The patients were randomly assigned to six groups (n = 30): control group (CG), scaling and root planning (SRP) + nanocrystalline hydroxyapatite dentifrices, SRP + nanocrystalline hydroxyapatite dentifrices + laser, SRP + herbal dentifrices, SRP + herbal dentifrices + laser, and SRP + laser. Each group was evaluated at baseline, 1 week, 1 month, and 6 months. In every visit of each patient, their clinical examination was done.Results:Among all groups’, repeated ANOVA measures and Kruskal–Wallis test was performed in which laser groups showed maximum reduction in DH in all indices while the CG showed minimum reduction in DH. The VRS values showed maximum reduction in SRP + nanocrystalline hydroxyapatite dentifrices + laser group with mean of 0.3 ± 0.5 and minimum reduction in CG with mean of 3.0 ± 0.5 (P < 0.001).Conclusion:Among all the groups, SRP + Nanocrystalline hydroxyapatite + Laser can be an effective treatment modality for DH.

Comparison of the effectiveness of three different desensitizing toothpastes in reducing dentin hypersensitivity: A 4-week clinical study

Aim:To compare the effectiveness of three different desensitizing toothpastes containing potassium salt, natural ingredients, and 8% arginine in reducing dentin hypersensitivity (DH).Materials and Methods:A 4-week study was conducted on 45 adult patients suffering from hypersensitivity associated with cervical abrasion of two or more teeth anterior to the molars. Patients were divided into three toothpaste groups as follows: Group I: potassium salt, Group II: herbal desensitizing paste containing natural ingredients, and Group III: 8% arginine. Using tactile stimulus and air stimulus, the sensitivity scores were recorded using Visual Analog Scale (VAS) at baseline, immediately after application, after 1 week, after 2 weeks, and after 4 weeks.Statistical Analysis:One-way ANOVA test and post hoc Tukey's test were used, and P ≤ 0.05 was considered statistically significant.Results:Group III showed significantly better reduction in DH at all time intervals when compared with Group I. Group III was significantly better than Group II at 1, 2, and 4 weeks.Conclusion:Desensitizing toothpaste containing 8% arginine was found to be the most effective in the reduction of DH after a single application up to a period of 4 weeks followed by herbal desensitizing toothpaste and potassium salt-containing toothpaste.

Comparison of Clinical Efficacy of Pro-Argin and NovaMin Toothpastes in Relieving Dentin Hypersensitivity: A Systematic Review and Meta-analysis.

To compare the clinical efficacy of toothpastes containing Pro-Argin and NovaMin as dentin hypersensitivity (DH) treatment. A systematic review and meta-analysis based on PRISMA was conducted (PROSPERO registration CRD42018095367). Electronic searches were performed in Pubmed, Scopus, Cochrane Library, Web of Science, Virtual Health Library and Open Grey until June 2018, with the terms [pro-argin OR arginine] AND [novamin OR calcium sodium phosphosilicate OR calcium sodium phospho silicate]. Randomised and non-randomised clinical trials comparing DH reduction in adults given Pro-argin-containing toothpastes and NovaMin-containing toothpastes were included. Study selection and quality assessment with Cochrane tool were performed. In the meta-analysis, the comparison between desensitising toothpastes was assessed by standardised mean difference (SMD) with 95% confidence intervals (CI). Certainty of evidence was evaluated with GRADE. Five studies fulfilled the inclusion criteria. In four included studies, a reduction in the DH under tactile stimulus between baseline and post-application times for both toothpastes was demonstrated. Three studies were suitable for meta-analysis. No statistically significant difference between the two toothpastes for DH reduction was observed at immediate (SMD = -1.05, CI = -3.52;1.41), 2-week (SMD = -0.55, CI = -2.59;1.48) and 4-week (SMD = -0.49, CI = -2.78;1.81) follow-up. Certainty of the evidence was very low. Included studies presented a high risk of bias. Pro-argin-containing and NovaMin-containing toothpastes showed effectiveness for DH reduction. No statistically significant difference between the two toothpastes was found. Thus, both can be prescribed to treat DH in adults with equivalent effectiveness up to four weeks.