Reaction Of Chloroacetic Acid Research Articles

Synthesis of Some new 2-(4-Aryliminophenoxy)N-Arylacetamide Via p-hydroxy benzaldehyde.

Chloroacetamide derivatives (2a-g) have been prepared through reaction of chloroacetyl chloride(1) (which prepared by the reaction of chloroacetic acid with thionyl chloride) with primary aromatic amines and sulfa compounds to afford compounds (2a-g) which then reacted with p-hydroxy benzaldehyde via Williamson reaction to obtaine the new compounds 2-(4-formyl phenoxy)-N-aryl acetamide (3a-g). Finally , compounds (3a-g) will be use as a good synthon to prepare the Schiff bases represented by compounds 2-(4-aryliminophenoxy)-N-arylacetamide (4a-g). through , reaction with some primary aromatic amine. All the prepared compounds were investigated by the available physical and spectroscopic methods.

Synthesis of Some new 2-(4-Aryliminophenoxy)N-Arylacetamide Via p-hydroxy benzaldehyde.

Chloroacetamide derivatives (2a-g) have been prepared through reaction of chloroacetyl chloride(1) (which prepared by the reaction of chloroacetic acid with thionyl chloride) with primary aromatic amines and sulfa compounds to afford compounds (2a-g) which then reacted with p-hydroxy benzaldehyde via Williamson reaction to obtaine the new compounds 2-(4-formyl phenoxy)-N-aryl acetamide (3a-g). Finally , compounds (3a-g) will be use as a good synthon to prepare the Schiff bases represented by compounds 2-(4-aryliminophenoxy)-N-arylacetamide (4a-g). through , reaction with some primary aromatic amine. All the prepared compounds were investigated by the available physical and spectroscopic methods.

PREPARATION & FORMULATION, OF TWO ACTIVE INGREDIENTS AS A PLANT GROWTH REGULATORS AND THEIR EVALUATION ON TOMATO.

Two active ingredients of plant growth hormones like auxins have been prepared. Para-Chlorophenoxyacetic acid (PCPA) and -Naphthoxyacetic acid (BNOA); via the reaction of chloroacetic acid with p-chlorophenol and beta-naphthol respectively in alkaline solution. The crude compounds were purified and characterized by their physical constants, infrared spectroscopy (FTIR) and gas chromatographic technique (GC).These compounds were formulated as a soluble liquid mixture (SL) in a concentration of 0.13% PCPA + 0.13% BNOA, which is ready for using and easily absorbing via the vegetative parts . According to that the prepared acids were converted to a water soluble triethanolamine salts since the original materials were solids and synthetically insoluble in water. Surfactants were added to the formula to increase the activity and the wetting area. The formula was subjected to a storage test to evaluate its stability, and evaluate on a tomato grown in a greenhouse to determine the efficacy of the active ingredient by spraying the flowering system with different concentrations (10, 20, 30, 40) ppm. The results which have been recorded after two weeks revealed that compound had high efficacy at concentration of 30 ppm. They enhanced the fruit setting, reduced flowers drop and improved the size and quality of fruits with a remarkable increase of the yield.

Kinetics of reaction of sodium arsenite with chloroacetic acid in mixed solvents and effect of the nature of the cation of alkali metal hydroxide on the rate of Meyer reaction

The rate constants of the reaction of sodium arsenite with chloroacetic acid in mixtures of water with alcohols, acetone, tetrahydrofuran, dimethyl sulfoxide, dimethoxymethane, and 1,4-dioxane at 25°C were determined. By the examples of the reaction of chloroacetic acid with the lithium, sodium and potassium arsenites the effect of the nature of alkali metal hydroxide cation on the reaction rate of Meyer reaction is considered.

Lithium- α-lithioacetate and β-lithiopropionate: useful intermediates in organic synthesis

The reaction of chloroacetic acid and 3-chloropropionic acid with a base (LDA or Bu n Li, respectively) and then with an excess of lithium and a catalytic amount of 4,4′-di- tert-butylbiphenyl (DTBB, 5%) in the presence of different electrophiles [Bu t CHO, PhCHO, Et 2CO, (CH 2) 5CO, PhCOMe] in THF at −78°C leads, after hydrolysis with water, to the expected hydroxy acids, which in the second case are directly cyclised under acidic conditions to give the expected γ-lactones.

Über die Reaktion von Chloroacetyl-2,4,6-trimethylbenzen mit SF 4 in Gegenwart von wasserfreiem Fluorwasserstoff

Reactions of chloroacetic acid with sulfur tetrafluoride and mesitylene give besides chlorofluoroethanes, small yields of 2-chloro-1,1-difluoro-ethylmesitylene and chloro- acetylmesitylene. Our results have shown that in the reaction of chloroacetyl- mesitylene, SF 4 and an excess of HF, formation of 2-chloro-1,1-difluoroethylmesitylene took place. This result shows that the formation of 2-chloro-1,1-difluoroethylmesitylene in the reaction of chloroacetic acid with SF 4 and mesitylene cannot be realized exclusively via fluoroalkylation of mesitylene with CH 2ClCF 2 + cations as previously formulated.

The use of chloroacetic acid in the mitsunobu reaction.

Reaction of chloroacetic acid with TPP-DEAD was found to be very effective for the inversion of sterically congested alcohols, including carbohydrates and nucleosides.

Reactions of thiourea with chloro- and bromoacetic acids

The reaction of chloroacetic acid with thiourea represents an SN2 substitution of chlorine by sulphur atom and is about two orders of magnitude slower than that of bromoacetic acid. Chloroacetate ion reacts slower than chloroacetic acid only about 30%. The acid catalyzed splitting off of hydroxyl group from the formed tetrahedral intermediate is rate-limiting in the cyclization of the S-carboxylatomethyleneisothiouronium salt, formation of the intermediate being rate-limiting below pH 2.

2-Aminothiazolin-4-one and 2-Iminothiazolidine-4-one Derivatives. Part I. The Reaction of Chloroacetic Acid with N-Monoalkylthiourea.

2-Aminothiazolin-4-one and 2-Iminothiazolidine-4-one Derivatives. Part I. The Reaction of Chloroacetic Acid with N-Monoalkylthiourea.

Free-radical addition of chloroacetic acid and of methyl chloroacetate to ?-olefins

1. The reaction of chloroacetic acid with α-olefins, initiated with t-butyl peroxide, leads to the formation of α-chloro carboxylic acids. Simultaneously, the corresponding chloroacetic esters are formed by an ionic mechanism. 2. Methyl chloroacetate adds to a α-olefins with formation of methyl α-chloro carboxylates.