ObjectivesMPV has been shown to be as a predictor of platelet activation which plays an important role in pathophysiology of atherosclerosis. Elevated RDW values are shown to be associated with worse prognosii in heart failure, coronary artery disease, pulmonary hypertension and peripheral arterial disease. In our study we aim to investigate the effect of statin on hematologic parameters in stable coronary artery disease.MethodWe retrospectively analysed statin naive patients who had gone coronary angiography for stable coronary artery disease between June 2012 and June 2013. MPV and RDW values, before and after statin use, are compared.ResultsAfter a mean follow up period of 58 day (minimum 17, maximum 720), in total of 121 patient while RDW levels were significantly different before and after statin use (p=0.001), MPV levels after treatment with statin didn’t reach an significant difference (p=0.325).ConclusionIn conclusion treatment with statin significantly reduce the RDW levels in stable coronary artery disease which confirms the antiinflammatory effect of statins. But decrease of RDW levels whether associated with prognosis in stable coronary artery disese or not has to established by multi center, prospective studies in large populations. ObjectivesMPV has been shown to be as a predictor of platelet activation which plays an important role in pathophysiology of atherosclerosis. Elevated RDW values are shown to be associated with worse prognosii in heart failure, coronary artery disease, pulmonary hypertension and peripheral arterial disease. In our study we aim to investigate the effect of statin on hematologic parameters in stable coronary artery disease. MPV has been shown to be as a predictor of platelet activation which plays an important role in pathophysiology of atherosclerosis. Elevated RDW values are shown to be associated with worse prognosii in heart failure, coronary artery disease, pulmonary hypertension and peripheral arterial disease. In our study we aim to investigate the effect of statin on hematologic parameters in stable coronary artery disease. MethodWe retrospectively analysed statin naive patients who had gone coronary angiography for stable coronary artery disease between June 2012 and June 2013. MPV and RDW values, before and after statin use, are compared. We retrospectively analysed statin naive patients who had gone coronary angiography for stable coronary artery disease between June 2012 and June 2013. MPV and RDW values, before and after statin use, are compared. ResultsAfter a mean follow up period of 58 day (minimum 17, maximum 720), in total of 121 patient while RDW levels were significantly different before and after statin use (p=0.001), MPV levels after treatment with statin didn’t reach an significant difference (p=0.325). After a mean follow up period of 58 day (minimum 17, maximum 720), in total of 121 patient while RDW levels were significantly different before and after statin use (p=0.001), MPV levels after treatment with statin didn’t reach an significant difference (p=0.325). ConclusionIn conclusion treatment with statin significantly reduce the RDW levels in stable coronary artery disease which confirms the antiinflammatory effect of statins. But decrease of RDW levels whether associated with prognosis in stable coronary artery disese or not has to established by multi center, prospective studies in large populations. In conclusion treatment with statin significantly reduce the RDW levels in stable coronary artery disease which confirms the antiinflammatory effect of statins. But decrease of RDW levels whether associated with prognosis in stable coronary artery disese or not has to established by multi center, prospective studies in large populations.