This article discusses the global Mittag-Leffler projective synchronization (GM-LPS) on fractional-order quaternion-valued neural networks (FOQVNNs) including mixed delays and impulses. The effects of various types of delay factors and impulses on Mittag-Leffler projective synchronization performance are simultaneously explored. Based on Banach contractive mapping principle, the existence result of solution to the considered systems is derived Applying the Lyapunov direct method, inequality analysis technique and generalized fractional Razumikhin theorem, the algebraic criteria for ensuring global Mittag-Leffler projective synchronization by designing the hybrid controllers are proposed. The result of algebraic inequality greatly reduces the computational complexity to some extent. Combining the different orders of Caputo derivative and MATLAB toolbox, the simulations are given to further validate the obtained results.