Rational Sequence Research Articles

Порівняльний аналіз адаптивних можливостей організму школярів 10–12 років

This article explores the definition of the factor structure of adaptive capabilities in the process of age development in boys 10–12 years old, who were engaged in physical education in physical education lessons. In this study, we evaluated: the adaptive potential of the system behind the Baevsky method; the functional state of the external respiration apparatus according to the Stange test and the Genchi test; body energy potential – «double product» and Robinson index. Assessment of physical fitness was carried out during the annual compulsory assessment of student youth educational institution in accordance with the instructions on the organization of the annual assessment of physical fitness of the population of Ukraine. Our research was carried out in secondary school № 45 in Kharkiv. They were attended by boys of 10-12 years of age (78 people). It has been established that physical education, which is limited only to physical education lessons, does not contribute to the effective improvement of adaptive capabilities of the body. The results of factor analysis showed changes in the factor structure of adaptive capabilities in the process of age development in boys. Moreover, changes in the factor structure in 12-year-old boys are more significant, which is associated with the terms of sensitive periods of the development of motor qualities. The results obtained are of prognostic importance for the rational sequence of using the totality and the amount of means and methods of physical education in this age period for a given age group.

Protein engineering of the aldoxime dehydratase from Bacillus sp. OxB-1 based on a rational sequence alignment approach

Recently, the program INTMSAlign_HiSol for identifying aggregation hotspots in proteins only requiring secondary structure data was introduced. We explored the utility of this program further and applied it for engineering of the aldoxime dehydratase from Bacillus sp. OxB-1. Towards this end, the effect of inverting the hydropathy at selected positions of the amino acid sequence on the enzymatic activity was studied leading to 60% of our constructed variants, which showed improved activity. In part, this activity increase can be rationalised by an improved heme incorporation of the variants. For example, a single mutation gave a 1.8 fold increased enzymatic activity and 30% improved absolute heme incorporation.

ПЛАНУВАННЯ ЗОВНІШНЬОЕКОНОМІЧНОЇ ДІЯЛЬНОСТІ ЯК ФАКТОР ПІДВИЩЕННЯ КОНКУРЕНТОСПРОМОЖНОСТІ ПІДПРИЄМСТВА НА СВІТОВОМУ РИНКУ

At the present stage of market relations, competition plays an extremely important role not only as a major factor in the development of individual enterprises, but also entire countries. The rapid processes of globalization make it possible to expand markets, but not every company can compete with other firms in foreign markets. The article examines the concepts of “competition” and “competitiveness of the enterprise” in foreign markets. Since today in the modern world competition is the driving force of any economy, without it the existence and development of the economy in general is impossible. The success of any business depends on the ability to compete in the market of goods or services. In the period of globalization and integration in the international space, the formation of a rational sequence of planning such activities is becoming increasingly important for enterprises engaged in foreign economic activity. This type of management activity contributes to obtaining additional profits through the use of the benefits of international labor and international integration, as well as identifying prospects and possible options for the development of foreign economic activity of organizations. That is why the technology of foreign economic activity planning is becoming especially relevant today. The article considers the factors influencing the planning of foreign economic activity of the enterprise, investigates the theoretical foundations of planning, suggests ways to improve the planning of foreign economic activity of the enterprise to increase competitiveness. The company’s success in the domestic or global market is its competitiveness, and as a result there is stability in the market. Competitiveness is the ability of an enterprise to conduct a fair competition in the chosen market, using all its resources productively, and as a result to make a profit. If the company occupies a leading position in the competitive market, then its product is in demand from consumers and has some advantages over the products of competitors. Managing the competitiveness of the enterprise is partly a function of general management, the purpose of which is to ensure the viability and sustainable operation of the enterprise in the event of any changes in the external environment. International competitiveness is the achievement by an enterprise of competitive advantages in competition on the international market. The study of competitiveness revealed its factors that influence the planning of imports. Internal factors depend on the nature of the enterprise, while external – on the state of the environment. Thus, successful foreign economic activity is determined by the optimal organizational structure of the department of foreign economic activity, coordination of all departments and specialists who provide export-import operations of the enterprise.

Management of Business Processes and Export-Import Activity of Industrial Enterprises in the Digital Economy

In the conditions of the digital economy and integration in the international space, the management of business processes and the formation of a rational sequence of planning such activities are becoming increasingly important for enterprises engaged in export-import activities. The authors investigated the features of business process management of an industrial enterprise and their export-import activity management features. For example, key indicators of efficiency and indicators of productivity of business process of the industrial enterprise, to investigate tendencies of export-import activity of the industrial enterprises are considered.The study allowed to offer tools for business process management and export-import activities of industrial enterprises in the digital economy, namely the Algorithm for the formation of the market strategy of the enterprise to begin the implementation of the export-import activity, the indicator of the integrated economic effect from the export-import activity and the Scenario of management of export-import activity of industrial enterprises in interrelation with the management of business processes, which are used as a basis for strategic and operational planning, and later will be used to control plans.

From satisfaction to loyalty: the role of emotional structures in the process of transition from satisfaction to loyalty

PurposeSatisfaction and loyalty as vital and strategic concepts in marketing literature are highly important to companies and marketers. The review of the existing literature reveals a gap of the role of emotional constructs that can begin in a regular and rational sequence of satisfaction and ultimately lead to the formation of consumer loyalty. Hence, in the current study, we seek to answer the question of whether emotional constructs such as emotional attachment and love play a mediating role in the process of transitioning from satisfaction to loyalty in the correct sequence.Design/methodology/approachA total of 300 valid questionnaires on Smartphone and apparel brands were collected from respondents and analyzed using the partial least squares method.FindingsThe results showed that brand love is the strongest antecedent of brand loyalty and is the only variable that directly influences brand loyalty in comparison to satisfaction and emotional brand attachment. Moreover, the examination of indirect effects revealed that our assumption based on that the emotional structures such as emotional attachment and brand love play a mediating role in the process of transitioning from satisfaction to loyalty in a correct sequence is supported.Research limitations/implicationsGeneralizability needs to be established with a wider range of consumer groups. The survey was conducted in Iran and future research should assess the same product categories in other cultural settings as well as consider other product categories to assess the external validity of these results. The insights on consumers' brand relationships help brand managers devise effective brand management strategies.Practical implicationsThe managerial implications can guide managers toward enhancing the consumers' loyalty to the brand through a better understanding of the consumer loyalty process to a brand as well as better relational marketing practices.Originality/valueThe study validates the mediating role of emotional brand attachment and brand love in the relationship between brand satisfaction and brand loyalty; is one of the first to develop a conceptual model that examines the role of emotional structures in the process of transition from satisfaction to loyalty.; is one of few studies to develop the role of emotional structures in the form of a relational chain of brands in the process of transition from satisfaction to loyalty.

Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies.

The literature surrounding the use of antisense oligonucleotides continues to grow, with new disease and mechanistic applications constantly evolving. Furthermore, the discovery and advancement of novel chemistries continues to improve antisense delivery, stability and effectiveness. For each new application, a rational sequence design is recommended for each oligomer, as is chemistry and delivery optimization. To confirm oligomer delivery and antisense activity, a positive control AO sequence with well characterized target-specific effects is recommended. Here, we describe splice-switching antisense oligomer sequences targeting the ubiquitously expressed human and mouse SMN and Smn genes for use as control AOs for this purpose. We report two AO sequences that induce targeted skipping of SMN1/SMN2 exon 7 and two sequences targeting the Smn gene, that induce skipping of exon 5 and exon 7. These antisense sequences proved effective in inducing alternative splicing in both in vitro and in vivo models and are therefore broadly applicable as controls. Not surprisingly, we discovered a number of differences in efficiency of exon removal between the two species, further highlighting the differences in splice regulation between species.

On the orders of largest groups of automorphisms of compact Riemann surfaces

Let μ ( g ) be the largest possible order of a group of automorphisms of a compact Riemann surface of genus g ≥ 2 . The celebrated results of Accola-Maclachlan and Hurwitz-Macbeath, taken together say that μ ( g ) ranges between 8 ( g + 1 ) and 84 ( g − 1 ) and these two bounds are attained for infinitely many g . Here we prove that given a prime q > 167 congruent to −1 modulo 3, not congruent +1 modulo 5 and a prime p ≥ 84 q , μ ( g ) = ( 8 ( q + 4 ) / q ) ( g − 1 ) for g = q p m + 1 for infinitely many integers m . Furthermore we also prove that for any prime q for which p = q + 2 is a prime, μ ( g ) = ( 12 ( q + 2 ) / q ) ( g − 1 ) for g = q p m + 1 for infinitely many m . These mean that there exist an infinite rational sequence ( r n ) convergent to 8 and, assuming the truth of the Twin Prime Conjecture, an infinite rational sequence ( s n ) convergent to 12 together with infinite sets R n and S n of integers for which μ ( g ) = { r n ( g − 1 ) if g ∈ R n s n ( g − 1 ) if g ∈ S n and 8 , 12 are the unique numbers for which this can happen. A consequence of these results is the full understanding of the asymptotic's of μ . Namely if instead of μ = μ ( g ) we consider its normalization μ ˜ ( g ) = μ ( g ) / g then { 8 } ⊆ ( M d ) d ⊆ { 8 , 12 } , where M stands for the set of values of μ ˜ and the operator d for the set of accumulation points and, assuming the truth of the Twin Prime Conjecture, 12 ∈ ( M d ) d .

Environment -friendly processes: Electrocoagulation and Activated carbon filtration for reuse of textile wastewater

Electrocoagulation is a simple method used for removing contaminants and recycling wastewater by using aluminum, stainless steel and iron electrodes. Textile wastewater was collected from the textile processing industry. This promising treatment consists of two steps, electrocoagulation as a first step completed with Activated carbon filtration as a second step reported in this work. The contaminants of the solution combined in the situ forming metal hydroxide flocs, which filtered as a precipitate or skimmed as a float. To revenue the best advantage of this system, the two processes should run in a rational sequence. Several important parameters, such as applied potential, Electrode material and conductivity were studied to achieve higher removal efficiency. Scanning electron microscope (SEM) analysis, Atomic force microscopy (AFM) and the electrical connection of electrodes were investigated. The results showed clearly that the stainless steel electrode can enhance effectively color removal by 98.8 %, reduced COD to 256 mg /L, while Activated carbon filtration can almost remove the total dissolved solids (TDS) and, turbidity. The findings showed that in textile wastewater at pH=10.5 the stainless steel is superior to iron and aluminum as a sacrificial electrode material and Mono-polar Connection in Parallel is the best connection as it decreases the potential difference, and energy Consumption was 2.5 kWh/m3.

Selective E to Z isomerization of 1,3-Dienes Enabled by A Dinuclear Mechanism

The E/Z stereocontrol in a C=C bond is a fundamental issue in olefin synthesis. Although the thermodynamically more stable E geometry is readily addressable by thermal Z to E geometric isomerization through equilibrium, it has remained difficult to undergo thermal geometric isomerization to the reverse E to Z direction in a selective manner, because it requires kinetic trapping of Z-isomer with injection of chemical energy. Here we report that a dinuclear PdI−PdI complex mediates selective isomerization of E-1,3-diene to its Z-isomer without photoirradiation, where kinetic trapping is achieved through rational sequences of dinuclear elementary steps. The chemical energy required for the E to Z isomerization can be injected from an organic conjugate reaction through sharing of common Pd species.

Calculating the polarization in bipartite lattice models: Application to an extended Su-Schrieffer-Heeger model

We address the question of different representation of Bloch states for lattices with a basis, with a focus on topological systems. The representations differ in the relative phase of the Wannier functions corresponding to the diffferent basis members. We show that the phase can be chosen in such a way that the Wannier functions for the different sites in the basis both become eigenstates of the position operator in a particular band. A key step in showing this is the extension of the Brillouin zone. When the distance between sites within a unit cell is a rational number, $p/q$, the Brillouin extends by a factor of $q$. For irrational numbers, the Brillouin zone extends to infinity. In the case of rational distance, $p/q$, the Berry phase "lives" on a cyclic curve in the parameter space of the Hamiltonian, on the Brillouin zone extended by a factor of $q$. For irrational distances the most stable way to calculate the polarization is to approximate the distance as a rational sequence, and use the formulas derived here for rational numbers. The use of different bases are related to unitary transformations of the Hamiltonian, as such, the phase diagrams of topological systems are not altered, but each phase can acquire different topological characteristics when the basis is changed. In the example we use, an extended Su-Schrieffer-Heeger model, the use of the diagonal basis leads to toroidal knots in the Hamiltonian space, whose winding numbers give the polarization.

Cross-polarization kinetics and fractal nature of thermal equilibration in spin systems: From low-dimensional proton conductors to tripeptides

Cross-polarization with magic-angle spinning (CP MAS) kinetics (1H–13C and 1H–31P) between remote spins were studied in a series of selected materials: from poly-(vinyl phosphonic acid) (pVPA) to calcium hydroxyapatite (CaHA), poly(2-hydroxyethyl methacrylate) (pHEMA), glycine and ultimately to tripeptides (Gly-Pro-Gly, Gly-Phe-Gly and Gly-Gly-Gly). The selection was based on the working concept that the pathways of thermal equilibration in the proton bath should be linked to the structural features of materials. Therefore we attempted to cover the maximal range of dimensionality of conceivable fractal structures as depicted in numerous literature sources. The ‘stretched exponential’ decay was involved in a purely phenomenological way to describe the thermal equilibration during the polarization transfer between remote spins. Its ‘stretching’ index allowed determining the fractal dimensions (Dp) of equilibration pathways. The spin-diffusion model improved by the thermal equilibration in the proton bath was the most appropriate to describe the experimental CP kinetics in the studied series.The fractal dimensions obtained for studied compounds are very reasonable: CaHA and pVPA behave as one-dimensional systems, whereas pHEMA and glycine are close to 2D-systems, and tripeptides can be considered as ‘almost’ 3D-systems. This rational sequence allows us to state that the developed treatment of CP kinetics with included thermal equilibration can reproduce the fractal images of complex compounds. The thermal equilibration is mainly mediated through the strongest interatomic/intramolecular vibrations. In addition to elasticity, a peculiar role of high mobility of protons along H-bonds has to be stressed.

Emotional brand attachment and brand love: the emotional bridges in the process of transition from satisfaction to loyalty

Purpose Satisfaction and loyalty as vital and strategic concepts in the marketing literature are highly important to companies and marketers. The review of the existing literature reveals a gap of the role of emotional constructs that can begin in a regular and rational sequence of satisfaction and ultimately lead to the formation of consumer loyalty. Hence, this study aims to answer the question of whether emotional constructs such as emotional attachment and love play a mediating role in the process of transitioning from satisfaction to loyalty in the correct sequence. Design/methodology/approach A total of 300 valid questionnaires on smartphone and apparel brands were collected from respondents and analyzed using the partial least squares method. Findings The results showed that brand love is the strongest antecedent of brand loyalty and is the only variable that directly influences brand loyalty in comparison to satisfaction and emotional brand attachment. Moreover, the examination of indirect effects revealed that our assumption based on that the emotional structures such as emotional attachment and brand love play a mediating role in the process of transitioning from satisfaction to loyalty in a correct sequence is supported. Research limitations/implications Generalizability needs to be established with a wider range of consumer groups. The survey was conducted in Iran, and future research should assess the same product categories in other cultural settings as well as consider other product categories to assess the external validity of these results. The insights on consumers’ brand relationships help brand managers devise effective brand management strategies. Practical implications The managerial implications can guide managers toward enhancing the consumers’ loyalty to the brand through a better understanding of the consumer loyalty process to a brand as well as better relational marketing practices. Originality/value The study validates the mediating role of emotional brand attachment and brand love in the relationship between brand satisfaction and brand loyalty, is one of the first to develop a conceptual model that examines the role of emotional structures in the process of transition from satisfaction to loyalty, is one of few studies to develop the role of emotional structures in the form of a relational chain of brands in the process of transition from satisfaction to loyalty.

On a quaternionic sequence with Vietoris’ numbers

Special integers sequences have been the center of attention for many researchers, as well as the sequences of quaternions where its components are the elements of these sequences. Motivated by a rational sequence, we consider the quaternions with components Vietoris? numbers and investigate some of its properties. For this sequence a two and three term recurrence relation is established, as well as a Binet?s type formula. Moreover the generating function for this sequence is introduced and also the determinant of some tridiagonal matrices are used in order to find elements of this sequence.

Планування зовнішньоекономічної діяльності як фактор підвищення конкурентоспроможності підприємств на світовому ринку

In the process of globalization and international integration, the formation of a rational sequence of sales planning is becoming increasingly important for companies engaged in foreign economic activity. This type of management activity contributes to obtaining additional profits through the full use of the advantages of international labor and international integration, as well as by identifying opportunities for the development of foreign economic activity of organizations. The relevance of the chosen topic lies in the need for companies to always develop and improve sales activities through increased competition and the rapid development of foreign economic relations. Because the key to the «survival» of enterprises in today’s market economy is a well-established effective sales policy and its purposeful development. The article defines the structure and components of sales activities. Also, an important role and priority of effective management of the sales system in increasing the competitiveness of enterprises in world markets is specified. The peculiarities of understanding the term of «sales» in both the narrow and the broad sense are analyzed. Different approaches to determining the basic concepts of sales activity are systematized. The place of sales in the enterprise management system is considered. The main characteristics of strategic and tactical management of sales system are analyzed. The peculiarities of sales management at enterprises are distinguished. The strategic and operational solutions in the creation of sales system are examined. The current state of foreign economic and sales activity of the service company «Master Service» LLC is considered and ways to improve its foreign economic activity are proposed.

Improvement of nonmonotone deformation technology in plastic metal working

The production of semi-finished products made of refractory metals is considered. The advantage of parts production using combination of two types of straining with change in the straining direction: direct extrusion and equal-channel pressing is shown. The experimental investigation data of pure and simple shear for the semi-finished products processing made of tungsten and molybdenum are presented. Requirements for the tool providing diagonal flow and angular straining are formulated based on the analysis of the stress-strain state of the processes of axial symmetric extrusion and simple shear of plastically inhomogeneous body. Effectiveness evaluation of the combination of various types of fixtures and the rational sequence for using of diagonal flow and angular pressing is given. Experimental devices for practical application of the proposed technology are developed.

DETERMINATION OF TECHNOLOGICAL PARAMETERS OF CULINARY PRODUCTS PRODUCTION USING MIXTURES AND EMULSIONS FOR ADDITIVE TECHNOLOGIES

The article presents the results of research on the determination of rational technological parameters for the production of culinary products using dry
 mixtures and emulsions based on animal raw materials for additive technologies. It was found that when making products using mixtures and emulsions based on broiler chicken meat, as well as a combination of broiler chicken meat and pork, pork and beef (ratio 1:1) rational height of the layer, which makes it possible to ensure stability and safety of the product shape (with a fixed diameter of the opening of the culinary syringe – 7 mm and the optimal length of the layer - 100 mm), is from 14–21 mm (with a layer width of 7 mm) and up to 133–154 mm (with a layer width of 98 mm), which allows for improved structural and mechanical (SSL – 1090.7–1099.9 Pa) and
 functional and technological indicators of these products (WHC – 92.7–97.5%). The rational sequence of application and the duration of chopping of the main and auxiliary raw materials for the manufacture of emulsions, the duration of
 preparation (3 minutes), the degree of hydration (1:2 – 1:3) and the temperature of water for the reduction of dry mixtures
 (60±1° C) were established, which made it possible to develop technological schemes for the production of culinary products using additive technologies.

О НОВЫХ, РАВНОМЕРНО РАСПРЕДЕЛЕННЫХ, МНОГОМЕРНЫХ ПОСЛЕДОВАТЕЛЬНОСТЯХ

Целью статьи является исследование одного важного свойства равномерности ЛП

Atomicity and density of Puiseux monoids

A Puiseux monoid is an additive submonoid consisting of non-negative rationals. Although the operation of addition is continuous with respect to the standard topology, the set of irreducibles of a Puiseux monoid is, in general, difficult to describe. Here, we use topological density to understand how much a Puiseux monoid, as well as its set of irreducibles, spread throughout the real line. First, we separate Puiseux monoids according to their density, and we characterize monoids in each of these classes in terms of generating sets and sets of irreducibles. Then we study the density of the difference group, the root closure, and the conductor semigroup of a Puiseux monoid. Finally, we prove that every Puiseux monoid generated by a strictly increasing sequence of rationals is nowhere dense in the real line and has empty conductor.

Метод препарування передньої стегнової ділянки для встановлення фетальної анатомічної мінливості судинно-нервових утворень

Determining of projection-syntopic relationships of vasculonervous structures within the femoral ring, femoral triangle, and obturator and adductor canal in human fetuses is particularly important in fetal surgery, and requires the use of an appropriate set of methods of morphological examination. Obtaining data on the topographic and anatomical features of nerves, superficial and deep blood vessels of the anterior femoral region during the fetal period of human ontogenesis is a topical urgent task of fetal anatomy. The purpose of the study was to determine the method of the most rational sequence of actions during the preparation of the vasculonervous structures of the anterior femoral region in human fetuses to obtain standard results suitable for comparison in the age aspect. Material and methods. The study was performed on 80 human fetuses 81.0-375.0 mm parietal-coccygeal length using macromicroscopic preparation. After the selected sequence of preparation of nerves and vessels of the anterior femoral region in human fetuses 4-10 months we used additional methods such as vascular injection, surface staining of dissected vessels and nerves and morphometry to determine the forms of their age and individual anatomical variability. Results and discussion. The chosen sequence of preparation of nerves and vessels of the anterior femoral region in human fetuses allowed determining the forms of their age and individual anatomical variability. In particular, features of intramuscular branching of nerves and arteries in the muscles of the anterior and medial femoral groups, anatomical variability of the femoral artery and its branches, variant anatomy of the great saphenous vein, characterized by variability in shape, topography and bilateral asymmetry of its tributaries and formation of anastomoses were found in human fetuses. The identified connections and complexes of the femur cutaneous nerves, as well as areas of overlap and displacement are compensatory mechanisms in the peripheral nervous system and are observed not only between ontogenetically related nerves, but also nerves of different segmental affiliation. Conclusion. The proposed and tested method of preparation of vasculonervous structures of the anterior femoral region in human fetuses provides a standard for obtaining data on their typical and variant anatomy. The sequence of actions used during the preparation of the vasculonervous formations of the anterior femoral region of the human fetus preserves the natural appearance and relationships between the structures of the object of study. Age-related and individual fetal anatomical variability of vasculonervous formations of the anterior femoral region was discovered during the gradual preparation of the lumbar plexus branches, superficial and deep veins of the lower extremities, superficial and deep inguinal lymph nodes, and femoral artery branches

The place of transpapillary endoscopic interventions in complicated acute cholecystitis

Objective . To determine the need and role of transpapillary endoscopic interventions in acute cholecystitis complicated by the main bile ducts pathology based on refined diagnostics using modern radiology examination methods. Materials and methods . The experience of treatment of 1137 patients operated on for acute cholecystitis during the last three years was analyzed. A differentiated approach for the use of highly informative methods of radiology diagnostics was based on clinical, anamnestic, laboratory and ultrasound data. In the selected groups of increased risk of bile duct pathology, endoscopic ultrasonography and magnetic resonance cholapgiopancreatography were used to clarify the diagnosis. The need for these studies was substantiated in 23.4% of cases. Based on the data obtained, indications for minimally invasive interventions aimed at decompression and correction of pathological changes in the biliary tract were formulated. They were performed in 182 (16%) patients, mainly by the endoscopic transpapillary route. Results. The need for a detailed assessment of clinical, laboratory, and ultrasound data is shown, indicating a possible biliary tract pathology and justifying the use of high-tech methods of radiology diagnosis. The options of decompression interventions, their rational sequence and combinations in acute cholecystitis complicated by bile ducts pathology are considered. Attention is focused on the need for careful monitoring of the effectiveness of interventions with a view to timely correction. Using the proposed diagnostic and treatment algorithm, the mortality rate was 0.26%. Conclusion . In acute cholecystitis, a detailed assessment of clinical, laboratory, and ultrasound data allows us to identify the “alarming” symptoms of a possible bile ducts pathology. These patients require an in-depth assessment of the state of the biliary tract using high-tech non-invasive diagnostic methods — endoscopic ultrasonography or magnetic resonance cholangiopancreatography. The detected changes (choledocholithiasis, stenosis of large papilla of the duodenum) should be eliminated by endoscopic transpapillary interventions as the first stage of treatment before removal of the gallbladder.