Urban space vitality is a critical indicator for supporting rational urban spatial planning and updating and formulating sustainable development strategies. However, in many areas (e.g., aging urban areas), there is often a mismatch between the conditions of the physical built environment and its spatial attractiveness. Traditional methods based on physical space design theory often fail to accurately measure the spatial vitality of these areas. Street view images directly reflect the actual construction situation and effectively compensate for the lack of visual, subjective, perception dimension information. This study proposes a novel method that integrates objective and subjective dimensions to measure urban vitality, which is captured by incorporating spatial data of points of interest, building outlines, road networks, and street view images. Then, taking mobile phone signaling data as a source of ground truth validation, we choose Nanjing as a case study to demonstrate that our multidimensional fusion method exhibits higher explanatory power and better alignment with actual conditions by comparing it against single-dimensional methods. The results underscore the importance of integrating subjective and perceptual dimensions in measurements of urban vitality. We believe that the localized samples of the subjective perception survey will further enhance the accuracy and generalizability of this method in the future.