Controlled-release urea (CRU) is widely adopted to improve yields and nitrogen use efficiencies (NUEs) in rice. However, there are few studies on the effects of the mixed application of CRU and normal urea (at different N ratios) on rice yield, nitrogen efficiency, and grain quality. A series of simplified fertilization modes (SFMs) were set up in 2018–2019. CRU with release periods of 80 days and 120 days were mixed with urea at N ratios of 7:3, 6:4, 5:5, 4:6, and 3:7 and applied during the rice-growing season. We determined the rice yield, dry matter accumulation, NUEs, and grain quality. The yields of SFM_80_6/4 (CRU with release periods of 80 days were mixed with urea at N ratios of 6:4) and SFM_120_5/5 (CRU with release periods of 120 days were mixed with urea at N ratios of 5:5) were 3.69% and 4.39% higher than that of fractionated urea (FU), respectively, across 2018 and 2019. Combining the application of controlled-release urea and normal urea improved the dry matter accumulation, nitrogen accumulation, and nitrogen uptake rate when compared with FU. SFMs improved the processing quality and appearance quality of rice grains and did not reduce the cooking and eating quality. SFM_80_6/4 and SFM_120_5/5 are a one-time fertilization mode with high yield, high efficiency, and good grain quality, which is worthy of further promotion and application.
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