Pumped storage plant(PSP) is a high efficient emission-free technology to balance the unstable electricity generation from renewable energy. In order to meet the variable requirements from power grid, the pumped storage units need to change working conditions frequently and quickly. Pump turbines have to run in transient processes, which stability affects safe operation of PSP directly. The load rejection of pump turbine is studied in this work, wherein the coordinated regulation of valve and guide vane is applied in this transition. This work aims at increasing the internal fluid stability of pump turbine, by reducing the change rate of pressure and improving flow regime. The combination of theoretical analysis and numerical simulation is the main research method, wherein wall sliding mesh technique is used to achieve continuous movements of valve core and guide vanes. Detached eddy simulation is adopted to solve the transient flow field, the fluid is characterized by a series of parameters like turbulent kinetic energy, pressure fluctuation and vortex evolution, etc. The results prove that a great contribution made by this co-adjusting method, it is beneficial to operation stability of system, especially for the final phase of load rejection.