Matrix-valued functions play an important role in the development of algorithms for semidefinite programming problems. This paper studies generalized differential properties of such functions related to nonsmooth-smoothing Newton methods. The first part of this paper discusses basic properties such as the generalized derivative, Rademacher's theorem, ℬ-derivative, directional derivative, and semismoothness. The second part shows that the matrix absolute-value function, the matrix semidefinite-projection function, and the matrix projective residual function are strongly semismooth.