Race Training Research Articles

Serum amyloid A (SAA) concentration after training sessions in Arabian race and endurance horses

BackgroundSerum amyloid A (SAA) is the major acute phase protein in horses. Its concentration increases in various pathologies but also in response to prolonged, strenuous effort. The purpose of this study was to establish whether routine race and endurance training produces changes in the SAA level in Arabian horses. Additionally, the differences between SAA response in experienced endurance horses and endurance horses that were beginning their career were investigated.ResultsThere were no changes in SAA concentrations after race training and endurance training in experienced horses. In horses that were beginning their endurance training, exercise produced an increase in SAA level as compared with rest level.ConclusionIn Arabians, the SAA concentration seems to be a good indicator of endurance training but is useless in race training. The routine training of experienced horses, which were prepared for long distance rides, did not promote any changes in the SAA level. In contrast, a significant increase in the SAA concentration was observed in horses that were beginning their endurance training and were only prepared for moderate distance rides and underwent the same effort. Further research is needed to elucidate whether this difference reflects too heavy training or adaptation to an increasing workload. Additionally, the adaptation to long distance rides in Arabians may include a reduced acute phase response.

The effect of nebulized salbutamol or isotonic saline on exercise-induced bronchoconstriction in elite skaters following a 1,500-meter race: study protocol for a randomized controlled trial

BackgroundPrevalence of exercise-induced bronchoconstriction (EIB) is high in elite athletes, especially after many years training in cold and dry air conditions. The primary treatment of EIB is inhaling a short-acting beta-2-agonist such as salbutamol. However, professional speed skaters also inhale nebulized isotonic saline or tap water before and after a race or intense training. The use of nebulized isotonic saline or tap water to prevent EIB has not been studied before, raising questions about safety and efficacy. The aim of this study is to analyze the acute effect of nebulized isotonic saline or salbutamol on EIB in elite speed skaters following a1,500-meter race.MethodsThis randomized controlled trial compares single dose treatment of 1 mg nebulized salbutamol in 4 mL of isotonic saline, or with 5 mL of isotonic saline. A minimum of 13 participants will be allocated in each treatment group. Participants should be between 18 and 35 years of age and able to skate 1,500 m in less than 2 min 10 s (women) or 2 min 05 s (men). Repeated measurements of spirometry, forced oscillation technique, and electromyography will be performed before and after an official 1,500-m race. Primary outcome of the study is the difference in fall in FEV1 after exercise in the different treatment groups. The trial is currently enrolling participants.DiscussionElite athletes run the risk of pulmonary inflammation and remodeling as a consequence of their frequent exercise, and thus increased ventilation in cold and dry environments. Although inhalation of nebulized isotonic saline is commonplace, no study has ever investigated the safety or efficacy of this treatment.Trial registrationThis trial protocol was registered with the Dutch trial registration for clinical trials under number NTR3550

Exercise affects joint injury risk in young Thoroughbreds in training

The aim of this study was to identify exercise-related risk factors for carpal and metacarpo- and metatarso-phalangeal (MCP/MTP) joint injury occurrence in young Thoroughbreds in flat race training. In a 2-year prospective cohort study, daily exercise and joint injury data were collected from horses in 13 training yards in England. Four injury categories were defined: (1) localised to a carpal or MCP/MTP joint based on clinical examination and/or use of diagnostic analgesia with no diagnostic imaging performed; (2) localised to a carpal or MCP/MTP joint with no abnormalities detected on diagnostic images; (3) abnormality of subchondral bone and/or articular margin(s) identified using diagnostic imaging; (4) fracture or fragmentation identified by diagnostic imaging. Multivariable Cox regression analysis was conducted to determine risk factors for injury occurrence, by type (carpal or MCP/MTP) and category. Exercise distances at canter and high speed in different time periods were modelled as continuous time-varying variables.A total of 647 horses spent 7785months at risk of joint injury and 184 injuries were recorded. Increasing daily canter distance reduced the risk of Category 1 and Category 3 injuries whereas greater 30-day canter distances increased Category 4 injury risk. More weekly high-speed exercise increased Category 1 injury risk. MCP/MTP injury risk reduced with increasing daily canter distance but increased with accumulation of canter or high-speed exercise since entering training, whereas accumulation of canter exercise was marginally associated with reduced carpal injury risk. Risk of all injury types varied significantly between trainers. The results of this study suggest that regular canter exercise is generally beneficial for joint health, while accumulation of high-speed exercise detrimentally affects MCP/MTP joints.

Electronic Health Records and the Increasing Complexity of Medical Practice: “It Never Gets Easier, You Just Go Faster”

Electronic Health Records and the Increasing Complexity of Medical Practice: “It Never Gets Easier, You Just Go Faster”

Associations between yearling exercise and interruptions during race training in Thoroughbred racehorses

To investigate the effect of exercise during yearling sales preparation on the risk of interruptions during training in Thoroughbred racehorses. 114 Thoroughbred racehorses. Information regarding the daily exercise of yearlings during sales preparation was obtained prospectively from a convenience sample of stud farms. Yearlings were followed to entry into race training, and subsequently, daily training information was recorded until the end of the racing season. Competing-risks survival analysis was used to model time from entry into race training to voluntary training interruption (no known condition or disease identified) and time from entry into race training to involuntary training interruption (due to presence of a condition or disease) occurring before the first trial (practice race for education). Total hand walking time and mechanical walker time accumulated during sales preparation were the main exposures of interest. 82 of 114 (71.9%) horses had an interruption before the first trial; 65 (79%) interruptions were voluntary, and 17 (21%) interruptions were involuntary. Increased total hand walking time was significantly associated with decreased risk of voluntary interruptions, whereas longer cumulative distances at a canter were significantly associated with decreased risk of involuntary interruptions. Results identified an association between early exercise during sales preparation and decreased risk of voluntary interruption and increased risk of involuntary interruption during training of 2-year-old Thoroughbred racehorses. Further investigation into the effects of early exercise on racing performance is needed, but results have indicated that there may be an opportunity to modify early exercise programs.

Situated Thinking

This paper focuses on the contextualisation of the science of race in colonial British Malaya. I argue that, though British scientists brought their ideas of race and anthropological training with them to Malaya, the application and enunciation of those ideas underwent change owing to the scientists’ encounters with other ways of conceiving of human difference. The dominance of the local term for Indigenous people, Sakai, and the awareness within colonial circles of ‘tamer’ and ‘wilder’ sections of this generalised group had to be taken into account by anthropological research. Physical anthropological studies by scholars such as W.W. Skeat and Nelson Annandale had to be rationalised not only within the developments of anthropological thinking on race but also within the social circumstances of their subjects of study and the colonial situation in Malaya. The resulting science of race was thus deeply socialised in the colonial context of British Malaya.

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

The inflammatory response to vigorous exercise ranges from the mild symptoms of delayed-onset muscle soreness to debilitating injuries affecting soft tissue, joint, and bone. Although there is a great deal of information available on the inflammatory response to exercise in human athletes, less information is available regarding the inflammatory response to exercise in young horses undergoing training for racing careers. Here, we assessed the cytokine response to exercise in a group of young Thoroughbred racehorses during their initial training. Because there is interest in nonpharmacologic approaches to control or ameliorate exercise-induced inflammation, we also examined the anti-inflammatory effect of a nutritional supplement fed to half of the horses undergoing training. Twenty-five Thoroughbred horses aged 2 years were followed through their initial race training. Peripheral blood samples were collected at various times during the exercise for the quantitation of lactic acid, oxidative stress, and inflammatory cytokine gene expression. There was an intensity-dependent effect of exercise on lactate, malondialdehyde, and proinflammatory cytokine gene expression. Although training itself was associated with an overall reduction in inflammatory markers, horses receiving the supplement exhibited further reductions in their indicators of inflammation. As such, this study provides novel evidence of nutritional supplementation reducing postexercise inflammation.

A forage-only diet alters the metabolic response of horses in training

Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from glucose to short-chain fatty acids (SCFA) due to more hindgut fermentation of fibre. Dietary fat inclusion has previously been shown to promote aerobic energy supply during exercise, but the contribution of SCFA to exercise metabolism has received little attention. This study compared metabolic response with exercise and lactate threshold (VLa4) in horses fed a forage-only diet (F) and a more traditional high-starch, low-energy forage diet (forage–concentrate diet - FC). The hypothesis was that diet F would increase plasma acetate concentration and increase VLa4 compared with diet FC. Six Standardbred geldings in race training were used in a 29-day change-over experiment. Plasma acetate, non-esterified fatty acids (NEFA), lactate, glucose and insulin concentrations and venous pH were measured in samples collected before, during and after a treadmill exercise test (ET, day 25) and muscle glycogen concentrations before and after ET. Plasma acetate concentration was higher before and after exercise in horses on diet F compared with diet FC, and there was a tendency (P = 0.09) for increased VLa4 on diet F. Venous pH and plasma glucose concentrations during exercise were higher in horses on diet F than diet FC, as was plasma NEFA on the day after ET. Plasma insulin and muscle glycogen concentrations were lower for diet F, but glycogen utilisation was similar for the two diets. The results show that a high-energy, forage-only diet alters the metabolic response to exercise and, with the exception of lowered glycogen stores, appears to have positive rather than negative effects on performance traits.

Prevalence of gastric ulcers and relationship to other parameters in Standardbred racehorses

Gastric ulcer prevalence rate is reported to be 60-90% in racehorses. This study examined a population of 40 Standardbred horses in race training and assessed the relationship of ulcers to performance history and body condition score (BCS). Forty Standardbreds on two racing facilities in southern Michigan were examined during the last 2 weeks of December 2007 and the second week of January 2008. Age of horses (as of January 1) ranged from 3 to 12 years. Squamous epithelial ulcers were graded (0-4) using an established scoring system during gastroscopic examinations and BCS was recorded (1 to 9 scale). Trainers graded racing performance of each horse on a scale of A to F, with A being best. Horses were grouped according to gender, age, and BCS. Prevalence of ulcers was similar between facilities (50% and 56%) but the mean prevalence (52.5%) was lower than in previous reports. Ulcer score was not related to gender (P=0.84), age (P=0.72), BCS (P=0.64), or performance history (P=0.55). These findings suggest that commonly cited prevalence rates of ulcers may not be consistent for all populations of racehorses. Further, given that less than 20% of the horses examined had an ulcer score grade 2 or higher, the impact that ulcers have on performance may be overestimated in some equine populations. Finally, this study clearly demonstrates that a gastroscopic examination is necessary to determine presence of ulcers, rather than assuming their presence based on decreased performance or low body condition score.

Transection of the lateral and long digital extensor tendons in racehorses

To report on the outcome of wounds to the hindlimb of racehorses, and horses with the intended use of racing, where both the long digital extensor (LoDE) and lateral digital extensor (LaDE) tendons had been completely transected. Retrospective case series. Records of all horses admitted with hindlimb lacerations between 2002 and 2009 were examined for cases where both the LoDE and LaDE tendons in the hindlimb had been severed, and specifically in horses intended to be used for racing. Outcome was assessed via retrieval of race records and via telephone questioning of the owners. In total, 589 records were retrieved and 34 horses met the inclusion criteria: 26 horses (76%) had proximal wounds that severed both the LoDE and LaDE tendons and 8 (24%) had more distal wounds, where the tendons were severed below the point at which they join; 14 horses (41%) were euthanased prior to discharge. Of the 20 horses discharged, 6 (30%) raced and 12 (60%) did not; 2 (10%) of the treated horses, both Thoroughbred colts, were in race training and showing no signs of lameness at the time of the study. Of the 34 horses presented for treatment, 18% went on to race. The prognosis for racing after transection of both hindlimb extensor tendons is poor. Clinicians may wish to consider these findings when formulating advice for clients regarding this injury in racehorses.

Radiographic evaluation of changes in the proximal phalanx of Thoroughbreds in race training

To evaluate changes in the cortical bone of the proximal phalanx of the fore-limbs of Thoroughbreds in response to training. Twenty-seven 2-year-old Thoroughbreds (20 females, 2 males, and 5 geldings). Horses were principally in training for races in a straight line and in a clockwise direction. Lateromedial and dorsopalmar radiographic views of each metacarpophalangeal joint were obtained before the horses started training and 1 year after starting exercise and racing. Width of the dorsal, palmar, lateral, and medial cortex and the width and thickness of the medulla were measured. Ratios (rather than absolute values) were used to remove the effect of differences in bone size among horses. 10 horses were lost from the study. Radiographs were obtained for 17 horses 1 year after starting training (9 horses raced in a clockwise direction, and 8 raced in clockwise and counterclockwise directions). There was no difference between the cortical bone in the right and left forelimbs at the start of the study. After training for 1 year, the palmar cortex in the right forelimb was significantly thicker than that in the left forelimb. The strain patterns, biomechanics of rapid exercise, and type of training most probably determined differences in the adaptive responses of the proximal phalanx. The data reported here can be used in the evaluation of weight-bearing distribution along the proximal phalanx and evaluation of the relationship between exercise and bone remodelling of the proximal phalanx.

Pulmonary inflammation due to exercise-induced pulmonary haemorrhage in Thoroughbred colts during race training

This study investigated the putative roles of inflammation and platelet-activating factor (PAF) in exercise-induced pulmonary haemorrhage (EIPH). Two-year-old Thoroughbred colts (n=37) were exercised on a racetrack for 5months before commencement of the study. Each colt was then exercised at 15-16m/s over 800-1000m and broncho-alveolar lavage fluid (BALF) was collected 24h later. The colts were subsequently divided into two groups on the basis of BALF analysis; an EIPH-positive group (presence of haemosiderophages, n=23) and an EIPH-negative group (absence of haemosiderophages, n=14). BALF from the EIPH-positive group had a significantly higher protein concentration (0.39±0.28 vs. 0.19±0.12mg/mL, P=0.031), higher PAF bioactivity (0.18±0.12 vs. 0.043±0.05 340:380nm ratio, P=0.042) and a higher lipid hydroperoxide concentration compared to the EIPH-negative group. There was also a lower nitrite concentration and reduced production of superoxide anion and hydrogen peroxide by alveolar macrophages in the EIPH-positive group. There was evidence of pulmonary inflammation and a decreased innate immune response of alveolar macrophages in EIPH-positive colts compared with the EIPH-negative group.

Evaluation of Intra-Articular Mesenchymal Stem Cells to Augment Healing of Microfractured Chondral Defects

This study evaluated intra-articular injection of bone marrow-derived mesenchymal stem cells (BMSCs) to augment healing with microfracture compared with microfracture alone. Ten horses (aged 2.5 to 5 years) had 1-cm2 defects arthroscopically created on both medial femoral condyles of the stifle joint (analogous to the human knee). Defects were debrided to subchondral bone followed by microfracture. One month later, 1 randomly selected medial femorotibial joint in each horse received an intra-articular injection of either 20 × 10(6) BMSCs with 22 mg of hyaluronan or 22 mg of hyaluronan alone. Horses were confined for 4 months, with hand walking commencing at 2 weeks and then increasing in duration and intensity. At 4 months, horses were subjected to strenuous treadmill exercise simulating race training until completion of the study at 12 months. Horses underwent musculoskeletal and radiographic examinations bimonthly and second-look arthroscopy at 6 months. Horses were euthanized 12 months after the defects were made, and the affected joints underwent magnetic resonance imaging and gross, histologic, histomorphometric, immunohistochemical, and biochemical examinations. Although there was no evidence of any clinically significant improvement in the joints injected with BMSCs, arthroscopic and gross evaluation confirmed a significant increase in repair tissue firmness and a trend for better overall repair tissue quality (cumulative score of all arthroscopic and gross grading criteria) in BMSC-treated joints. Immunohistochemical analysis showed significantly greater levels of aggrecan in repair tissue treated with BMSC injection. There were no other significant treatment effects. Although there was no significant difference clinically or histologically in the 2 groups, this study confirms that intra-articular BMSCs enhance cartilage repair quality with increased aggrecan content and tissue firmness. Clinical use of BMSCs in conjunction with microfracture of cartilage defects may be potentially beneficial.

Immune And Inflammatory Responses And Exercise Performance During 135 Miles Mountain Foot Race

Pronounced increases in white blood cells and C-reactive protein (CRP) have been found after ultramarathon races, however, their relationships with exercise performance are unclear. PURPOSE: Verify the relationship between immune and inflammatory responses and exercise performance during 135 miles race METHODS: It was studied 11 athletes (43±3 years; 170.4±1.9 cm height; 70.7±3.1 kg body weight; 16±3 years of race training; 122±18km/week of training volume) that participated of the "BAD 135 World Cup" mountain race called "Brazil 135 Ultramarathon". One week before the competition and in subsequent days, the athletes individually determined the critical velocity (CV) from 4 maximal running of 800, 1200, 1600, 2000m. So, the CV was determined by the angular coefficient of the linear fit of distance versus running time. Race and pause time were obtained by official race reports. Blood samples were collected pre and post race for determination of blood counts with five-part leucocyte differential (neutrophils, lymphocytes, monocytes, eosinophils, basophils) by automated haematology analyser and CRP by an auto-analyzer. All data were expressed by mean ± SEM, t Student test for dependent sample was used to comparisons and Pearson`s correlation coefficient was used for analyzing relationships (statistical significance P<0.05). RESULTS: The subjects completed the race in 46.6±3.1h, speed average of 3.1±0.2 mph, corresponding to 34.5±1.9% of CV and total pause time of 3.7±0.9 h. Leucocyte (123±23%) neutrophils (170±70%), monocytes (122±16%), basophils (-51±19%) and CRP (35,467±18,376%) changed significantly (P<0.05) from baseline to post race. Leucocyte and neutrophils levels at 135 miles were positively correlated (P<0.05) with absolute running velocity (r=0.70; 0.76, respectively) and running velocity relative to CV (r=0.92; 0.96, respectively) as well as inversely correlated (P<0.05) with race time (r= -0.75; - 0.80, respectively) and pause time (r= -0.66; -0.69, respectively). CONCLUSIONS: These data strengthen that the immune and inflammatory responses are elevated post race as well as they show that higher running intensity and lower race and pause time may be related to greater white blood cells levels in 135 miles ultramarathon mountain race. Supported by Capes, CNPq and FAPESP/BRAZIL.

Risk for Exercise Addiction: A Comparison of Triathletes Training for Sprint-, Olympic-, Half-Ironman-, and Ironman-Distance Triathlons

Researchers have noted that when taken to an excessive level, exercise may become addictive. This study investigated the risk of exercise addiction for triathletes using the Exercise Addiction Inventory (EAI; Terry, Szabo, &amp; Griffths, 2004). The sample consisted of 1,285 male and female triathletes, ranging in age from 18–70 years old. Results indicated that approximately 20% of triathletes are at risk for exercise addiction, and that training for longer distance races (i.e., Olympic, Half-Ironman, and Ironman) puts triathletes at greater risk for exercise addiction than training for shorter races (i.e., Sprint). No significant association was found between the risk for exercise addiction and the number of years of participating. However, as the number of weekly training hours increased, so did a triathlete’s risk for exercise addiction. At-risk triathletes need greater clinical attention, and further research should be conducted to help clinicians develop awareness and appropriate interventions.

The effect of year and season of birth, sex, sire, and breeder on ossification of the distal epiphyseal cartilage of the radial bone in Thoroughbred horses

The aim of this study was to evaluate the effect of specific factors on ossification of the distal epiphyseal cartilage of the radial bone in Thoroughbred horses. The study was carried out on 452 Thoroughbred horses, two years old, that were under race training. X-ray tests were conducted and interpreted every month starting at the 18th month of life and continuing until ossification of the distal epiphyseal cartilage of the radial bone occurred. In the statistical model, the year of birth, sex, birth season, sire, and breeder were treated as constant effects. Horses that were born in the spring season were characterized by a shorter time until the closure of the distal radial epiphyseal cartilage in comparison to horses born in the winter season; the difference between these times was found to be highly significant. Furthermore, it was shown that the ossification time of cartilage was also significantly influenced by the year of birth, the sire, and the breeder. Knowledge and monitoring of factors affecting the rate of somatic maturity in Thoroughbred horses can be useful in breeding and veterinary practices. This fact, in conjunction with the analysis of somatotrophic processes, will provide a basis for improving the feeding, training, and management system of Thoroughbred horses as well as aiding in the early diagnosis, treatment, or prevention of various diseases associated with intensive growth in the early period of life.

Sex Differences in Association of Race Performance, Skin-Fold Thicknesses, and Training Variables for Recreational Half-Marathon Runners

The purpose of this study was to investigate the association between selected skin-fold thicknesses and training variables with a half-marathon race time, for both male and female recreational runners, using bi- and multivariate analysis. In 52 men, two skin-fold thicknesses (abdominal and calf) were significantly and positively correlated with race time; whereas in 15 women, five (pectoral, mid-axilla, subscapular, abdominal, and suprailiac) showed positive and significant relations with total race time. In men, the mean weekly running distance, minimum distance run per week, maximum distance run per week, mean weekly hours of running, number of running training sessions per week, and mean speed of the training sessions were significantly and negatively related to total race time, but not in women. Interaction analyses suggested that race time was more strongly associated with anthropometry in women than men. Race time for the women was independently associated with the sum of eight skin-folds; but for the men, only the mean speed during training sessions was independently associated. Skin-fold thicknesses and training variables in these groups were differently related to race time according to their sex.

Metacarpal geometry changes during Thoroughbred race training are compatible with sagittal‐plane cantilever bending

Bending of the equine metacarpal bones during locomotion is poorly understood. Cantilever bending, in particular, may influence the loading of the metacarpal bones and surrounding structures in unique ways. We hypothesised that increased amounts of sagittal-plane cantilever bending may govern changes to the shape of the metacarpal bones of Thoroughbred racehorses during training. We hypothesised that this type of bending would require a linear change to occur in the combined second moment of area of the bones for sagittal-plane bending (I) during race training. Six Thoroughbred racehorses were used, who had all completed at least 4 years of race training at a commercial stable. The approximate change in I that had occurred during race training was computed from radiographic measurements at the start and end of training using a simple model of bone shape. A significant (P < 0.001), approximately linear pattern of change in I was observed in each horse, with the maximum change occurring proximally and the minimum change occurring distally. The pattern of change in I was compatible with the hypothesis that sagittal-plane cantilever bending governed changes to the shape of the metacarpal bones during race training.

The effect of training on plasma L-carnitine metabolism in purebred Arabian horses

1. Dynamic change of free serum L-carnitine concentration in relation to age, sex, and exercise in Anglo-Arabian Thoroughbred horses Francesca Arfuso, Claudia Giannetto, Elisabetta Giudice, Francesco Fazio, Giuseppe Piccione Journal of Equine Veterinary Science CrossRef

The cross-sectional area of the superficial digital flexor tendon of trained and untrained Thoroughbred racehorses

Twenty Thoroughbred racehorses were ultrasonographically evaluated to determine the relation between normal values of the cross-sectional area (CSA) of the right and left forelimbs superficial digital flexor tendons (SDFT) in the metacarpal region for trained and untrained Thoroughbreds racehorses. Ultrasonography revealed that CSA at 26cm distal to the accessory carpal bone is larger than other proximal levels, for either left or right forelimbs. In addition, the CSA at 2, 4, 6, 8, 10, 12 and 14cm distal to the accessory carpal bone of the left forelimb are larger (P&lt;0.05) for trained horses when compared with untrained horses. On the other hand, there was no significant difference (P&gt;0.05) between left and right forelimb for CSA of the SDFT, at any level, for either trained or untrained horses, and there was no significant difference between untrained or trained horses for the CSA of right forelimb. In conclusion, the CSA of the left forelimb SDFT for horses that had been in continuous race training remains larger when they were trained anticlockwise, contrary to horses that had not been training for more than one year.