Abstract
1. Dynamic change of free serum L-carnitine concentration in relation to age, sex, and exercise in Anglo-Arabian Thoroughbred horses Francesca Arfuso, Claudia Giannetto, Elisabetta Giudice, Francesco Fazio, Giuseppe Piccione Journal of Equine Veterinary Science CrossRef
Highlights
Racing or athletic ability is the main selection criterion in the breeding of warmblood horses
The aim of this study was to evaluate the effects of high-intensity exercise required for race training and for endurance training, on the plasma L-carnitine profile in purebred Arabian horses
In the group of 18 purebred Arabian horses, the resting plasma TG level was significantly lower in the last sampling as compared with those observed before the start of the training process (Table 1)
Summary
Racing or athletic ability is the main selection criterion in the breeding of warmblood horses. Exercise performance requires a high potential for lipid oxidation This process is dependent on the rate of fatty acid transport into the mitochondria. L-carnitine (3-hydroxy-4N-trimethylaminobutyrate) is a water-soluble quaternary amine It is present in muscle cells as a free form of L-carnitine and as fatty acid and acetyl esters. Synthesis of acetylcarnitine plays an important role in the regulation of the mitochondrial acetyl-CoA/CoA ratio. It equalizes the utilization of carbohydrates and fatty acids in energy production. In horses that are exercising, the intramuscular concentration of free L-carnitine decreases and the acetylcarnitine content increases equivalently, whereas the total L-carnitine pool remains unchanged (Foster and Harris, 1987a; Carlin et al, 1990). After short intensive exercise periods, the levels of intramuscular free L-carnitine and its esters return to their resting values in about 30 min (Harris and Foster, 1990)
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