Case Reports1 November 1951THE ARREST OF RECURRENT EMBOLISM DUE TO AURICULAR FIBRILLATION WITH MITRAL STENOSIS BY QUINIDINE-ANTICOAGULANT THERAPYHOWARD LACKAY, EDMUND L. HOUSEL, M.D.HOWARD LACKAYSearch for more papers by this author, EDMUND L. HOUSEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-5-1143 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA serious and often fatal complication of auricular fibrillation, especially when associated with mitral stenosis, is the production of intraauricular thrombosis and embolism. When embolism is recurrent, the condition is likely to be fatal unless normal auricular contractions are restored and the source of emboli is thereby eliminated. Although restoration of normal rhythm by quinidine therapy has been recommended generally in the treatment of uncomplicated auricular fibrillation of short duration, there is a natural hesitation among many physicians to employ this drug in the presence of long established auricular fibrillation with repeated embolic episodes complicating serious heart disease because of...Bibliography1. OppenheimerMann BSH: Results with quinidine in heart disease, J. A. M. A. 78: 1752, 1922. Google Scholar2. SmithBoland HLEW: The treatment of auricular fibrillation with quinidine and strychnine, J. A. M. A. 113: 1017, 1939. CrossrefGoogle Scholar3. CampbellGordon MFW: The quinidine treatment of auricular fibrillation, Quart. J. Med. 5: 205, 1936. Google Scholar4. Smith HL: Advisability of restoring normal rhythm, M. Clin. North America 24: 1083-1088, 1945. CrossrefGoogle Scholar5. Carter JB: Uses and abuses of quinidine, M. Clin. North America 29: 215-228, 1945. CrossrefGoogle Scholar6. WhiteBlumgart PDHL: Cessation of repeated pulmonary infarction and of congestive failure after termination of auricular fibrillation by quinidine therapy, J. Mt. Sinai Hosp. 8: 1095, 1942. Google Scholar7. Sokolow M: Quinidine in the treatment of benign auricular fibrillation with repeated emboli, Am. Heart J. 18: 494, 1939. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pennsylvania*Received for publication January 28, 1950. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAtrial fibrillation: villain or bystander in vascular brain injuryElectrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities studyAtrial Fibrillation: A Historical Perspective 1 November 1951Volume 35, Issue 5Page: 1143-1149KeywordsAtrial fibrillationCardiovascular therapyDrug therapyMitral stenosisThrombosis ePublished: 1 December 2008 Issue Published: 1 November 1951 PDF downloadLoading ...
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Jan 1, 1952
Sven Åkesson 
