As an emerging technology, origami exhibits rich nonlinear static and dynamic properties. However, simulating creases remains a key challenge hindering practice application, especially for volumetric (deformable) origami. Inspired by the bistable behavior and axial-rotational coupling mechanism of triangulated cylindrical origami (TCO), this paper proposes a novel combined truss-spring structure with additional inertial mechanism (TCTS-RIM) for low-frequency vibration isolation. Unlike pure TCO, the TCTS-RIM uses elastic linkages to simulate all creases and modifies crease positions, enhancing physical realization in engineering applications and offering tunable stiffness and inertia on demand. Static analysis shows the modified truss-spring structure in TCTS-RIM has superior quasi-linear negative stiffness compared to pure TCO, which enables a very wide quasi-zero stiffness (QZS) range via linear spring compensation. The wide QZS range for different loads can be realized by setting appropriate structural parameters. From system dynamic equations, nonlinear inertia, nonlinear quadratic force, and nonlinear damping due to RIM are identified and discussed. The Alternating frequency–time harmonic balance method is used to obtain the displacement transmissibility, and its parametric influencing investigations verify that the proposed TCTS-RIM has excellent low-frequency vibration isolation performance and rich tunability. Comparative discussions show the wide QZS range significantly reduces the resonance frequency, broadens the isolation frequency band, and yields superior dynamic performance versus pure TCO isolators. Moreover, equivalent mass, anti-resonance and softening behavior induced by the rotational inertia mechanism further enhance low-frequency vibration isolation performance. An experimental prototype is built, and experimental results validate the correctness of the theoretical analyses. This work presents a simple mechanical implementation of volumetric origami, which may progress the engineering applications of origami and provide a viable approach to low-frequency vibration control.