Device Quality Research Articles

Strategies for Improving the Utilization of Preventive Care Services: Application of Importance-Performance Gap Analysis Method.

The utilization of preventive care services is limited. Previous studies based on communities have looked at many types of barriers to preventive care (i.e., why not do). This study aimed to gain an insight into the key factors and performance gaps (i.e., why do and how to do) of people who attended a regional teaching hospital to undergo health check-ups using a purposive sampling method to recruit people to complete a self-administered questionnaire. Paired sample t-tests and importance–performance gap and regression analyses were performed. The results indicated that the participants’ wish to understand their health status, the quality of medical devices and the completeness of items, and process layout planning were the key factors that affect people’s health check-up behavior. Promoting the effectiveness of hospital performance may improve the positive cycle of people’s health check-up behavior from the community to the hospital. Continuing to promote the knowledge of preventive care services is necessary, and it is very important for people to have a good experience of undergoing health check-ups in the hospital. Important strategies for improving the utilization of preventive care services may include: meeting the person’s personalization needs, improving the quality of medical devices and the completeness of items, and having appropriate process layout planning, a detailed interpretation of the results, and further follow-ups in the hospital.

In Vivo Analysis of Intraoral Scanner Precision Using Open-Source 3D Software

Intraoral three-dimensional scanning techniques could be used to improve dental practice, leading to an improved overall quality of the prosthetic devices and improved comfort for the patient. An accurate and precise intraoral scanner allows proper diagnosis, follow-up evaluation, and prosthesis application. The aim of this research is to evaluate the precision of an intraoral scanners (Medit i500, Medit Corp., Seoul, Korea), using open-source software in the digital workflow. The precision was compared through repetitions of the scanning process of the upper dental arch, following superimpositions in the whole 3D arch area. It was possible to display colorimetric maps for qualitative comparison, and the deviations of the values were classified as clinically acceptable. Within the limitation of this study, the clinically acceptable in vivo frequency of points’ deviation, or the precision, was obtained in 98.8% ± 1.4%; therefore, the use of open-source software can be a viable option in the digital workflow, improving patient follow ups with the 3D model superimposition.

(Invited) Large Carrier Mobility in Graphene with Enhanced Shubnikov–De Haas Quantum Oscillations

Graphene devices are susceptible to the surrounding environment1-4. For example, the substrate in contact with graphene influences the device performance because the carriers are confined in two-dimensional (2D) atomic thickness. However, 2D van der Waals dielectric materials used as an interface modifier can provide a path to improve the device quality. In this paper, we report an enhanced mobility of 35000 cm2 V-1 s-1 in a CrOCl-coated monolayer graphene on the SiO2/Si substrate through a dielectric shielding effect. When monolayer graphene is sandwiched between two layers of 2D CrOCl insulator, the enhanced mobility can be 70000 cm2 V-1 s-1. Because of the enhanced mobility, the Shubnikov-de Haas (SdH) quantum oscillation is also observed with the amplitude linearly decreasing with increasing temperature, consistent with the standard Lifshitz-Kosevich theory, and the effect persists at temperatures up to 100 K. Our work paves a way to improve graphene mobility and realize nontrivial quantum states at high temperature for the exploration of potential applications in electronics.

THE ROLE OF HYDROXYUREA IN INCREASING PULSE OXIMETRY AMONG PATIENTS WITH SICKLE CELL DISEASE

To identify the influence of hydroxyurea (HU) on oxygen saturation levels among patients with Sickle Cell Disease (SCD). A cross-sectional study was carried out that evaluated the use of HU for at least 1 year and the oxygen saturation measured on the oximeter in patients recruited in a SCD cohort in Brazil. A total of 275 patients were evaluated and 132 were included in this study. Inclusion criteria were (i) SS genotype, (ii) age over 18 years, (iii) HU use for more than 1 year (iv) no HU use, (v) active follow-up. Patients who did not use HU were the control group. The HU group had 57 patients with a mean age of 32 (±13.38) years, 50.88% women and 49.12% men. The means of Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Heart Rate (HR) and Oxygen Saturation (SpO 2 ) in this group were, respectively, 117.95 (±15.52) mmHg, 65.39 (±11.22) mmHg, 81.40 (±14.55) bpm and 93.02 (±14.55)%. The Control group consisted of 32 patients, the mean age was 30.50 (±10.92) years, 56.25% were women and 43.75% were men. The means of SBP, DBP, HR and SpO 2 in the control were respectively 114.69 (±12.37) mmHg, 62.44 (±9.37) mmHg, 80.19 (±15.66) bpm and 90.16 (±6.16)%. The difference between SpO 2 in the groups was statistically significant (p = 0.01). In the other variables evaluated there was no statistical significance. Oxygen desaturation is common in SCD and predicts clinical severity. Hypoxemia is associated with risk of stroke, abnormal transcranial Doppler velocities, elevation of tricuspid regurgitation, diastolic dysfunction, increased incidence of vaso-occlusive crises and chest syndrome sharp. Pulse oximetry is a non-invasive method of measuring oxyhemoglobin saturation. Peripheral perfusion, external light sources, and skin color and device quality should be observed. HU is the primary therapy in SCD and is capable of increasing the production of fetal hemoglobin (HbF). Studies have shown a strong correlation between peripheral SpO 2 and HbF level, so treatments that elevate HbF should impact desaturation and be beneficial for complications associated with hypoxia. In the United Kingdom, there is already a recommendation from the HU for the treatment of chronic hypoxemia in SCD. The measurement of SpO 2 is crucial for effective management in SCD. The association between HbF and SpO 2 reaffirms the importance of interventions that are able to increase both, like the HU. This study shows that the patients under use of HU had a significantly higher SpO 2 when compared to patients without it.

Blockchain Empowered Federated Learning Ecosystem for Securing Consumer IoT Features Analysis.

Resource constraint Consumer Internet of Things (CIoT) is controlled through gateway devices (e.g., smartphones, computers, etc.) that are connected to Mobile Edge Computing (MEC) servers or cloud regulated by a third party. Recently Machine Learning (ML) has been widely used in automation, consumer behavior analysis, device quality upgradation, etc. Typical ML predicts by analyzing customers’ raw data in a centralized system which raises the security and privacy issues such as data leakage, privacy violation, single point of failure, etc. To overcome the problems, Federated Learning (FL) developed an initial solution to ensure services without sharing personal data. In FL, a centralized aggregator collaborates and makes an average for a global model used for the next round of training. However, the centralized aggregator raised the same issues, such as a single point of control leaking the updated model and interrupting the entire process. Additionally, research claims data can be retrieved from model parameters. Beyond that, since the Gateway (GW) device has full access to the raw data, it can also threaten the entire ecosystem. This research contributes a blockchain-controlled, edge intelligence federated learning framework for a distributed learning platform for CIoT. The federated learning platform allows collaborative learning with users’ shared data, and the blockchain network replaces the centralized aggregator and ensures secure participation of gateway devices in the ecosystem. Furthermore, blockchain is trustless, immutable, and anonymous, encouraging CIoT end users to participate. We evaluated the framework and federated learning outcomes using the well-known Stanford Cars dataset. Experimental results prove the effectiveness of the proposed framework.

Safety of handling of medical devices at all stages of their life cycle

The review describes the main points of the life cycle of a medical device, considers three stages of regulation of medical devices: pre-market, market and post-sale. The main attention is paid to post-sale supervision, as an activity for monitoring used medical devices, collecting information about the quality, safety and effectiveness of medical devices.

Submammary Implantation of Internal Pulse Generators for Deep Brain Stimulation: Long-Term Follow-up of Device Acceptance and Quality of Life in Women

A submammary approach to implanting pulse generators is innovative and has yielded good aesthetic results in the current literature. It was our aim to make a comparison of patient device acceptance, tolerance, and complications between submammary and abdominal device locations in deep brain stimulation. Twenty-five and 28 patients were included in the submammary and abdominal groups, respectively. Our primary criterion was patient acceptance that was calculated using total Florida Patient Acceptance Survey (FPAS) scores in each group. Secondarily, tolerance was assessed in the submammary group by means of a specific questionnaire. Total FPAS scores from the submammary group [total FPAS: 77.1 versus 74.7, P=0.29] revealed no significant difference when compared with the abdominal group. The same similarities were observed regarding the 4 subscales: return to function [16.3 versus 15.8, P=0.53], device-related distress [22.0 versus 21.3, P=0.31], body image concerns [9.2 versus 8.6, P=0.14], and positive appraisal [17.8 versus 17.4, P=0.58]. Tolerance was reported as good by the majority of the women from the submammary group. There was no evidence of higher infection rates in the submammary implantation (SMI) group. SMI is a satisfactory alternative to other deep brain stimulation locations. SMI is a feasible option for any young woman who is eligible for deep brain stimulation.

Testing Scalable Bell Inequalities for Quantum Graph States on IBM Quantum Devices

Testing and verifying imperfect multi-qubit quantum devices are important as such noisy quantum devices are widely available today. Bell inequalities are known to be useful for testing and verifying the quality of the quantum devices from their nonlocal quantum states and local measurements. There have been many experiments demonstrating the violations of Bell inequalities, but they are limited in the number of qubits and the types of quantum states. We report violations of Bell inequalities on IBM Quantum devices based on the scalable and robust inequalities maximally violated by graph states as proposed by Baccari et al.. The violations are obtained from the quantum states of path graphs up to 57 and 21 qubits on a 65-qubit and two 27-qubit IBM Quantum devices, respectively, and from those of star graphs up to 11 qubits with quantum readout error mitigation (QREM). We are able to show violations of the inequalities on various graph states by constructing low-depth quantum circuits and by applying the QREM technique. We also point out that quantum circuits for star graph states of size <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> can be realized with circuits of depth <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$O(\sqrt {N})$ </tex-math></inline-formula> on subdivided honeycomb lattices which are the topology of the 65-qubit IBM Quantum device. Our experiments show encouraging results on the ability of existing quantum devices to prepare entangled quantum states and provide experimental evidence on the benefit of scalable Bell inequalities for testing them.

Novel Memristor-based Non-volatile D Latch and Flip Flop Designs

Abstract: Serial devices are the fundamental building elements of all digital electronic systems with memory. The non-volatile quality of sequential devices is necessary for quick data recovery after unexpected data loss, such as an unintentional power outage, which has sparked ongoing research and development into integrating a non-volatile memristor into CMOS devices. In this article, we examine using this technique to raise the caliber of nonvolatile D-latch. One memristor, a few transfer gates, and CMOS transducers are the sole components of the proposed D-latch, which sets it apart from conventional designs. Our design minimizes the negative impact of transistor threshold loss. In addition, a variety of memristor threshold values are available with our design

Geographical analysis of the reality of problems and obstacles to the health function in Ishaqi district

The problems related to the implementation of health services are among the most prominent spatial obstacles that contribute to the lack of projects for the health sector within the district. Perhaps the most prominent of these obstacles are the planning obstacles, as the district suffers from a clear population spread with the exception of the district’s center, which prevents the implementation of service projects due to the lack of a gathering A population that complies with the planning standards that focus on two aspects, namely, the population and spatial corresponds to the number of residents. A group of social problems constitute another obstacle to the implementation of these projects due to the customs and traditions that work on the reluctance of the population to use health services, especially with regard to women, and the economic aspects of the lack of Financial allocations, which represent an obstacle added to the previous factors in their direct impact on the health services sector, whether they are the creation of services or the sustainability of a service by providing the health services sector with the required health resources, whether they are devices, equipment and medicines. How much technological problems have played an important role in the decline of health services through the apparent backwardness in the quality of medical devices and the failure to keep pace with technological development, which in turn was reflected in the lack of efficiency of health services provided, and the research found that there is a clear deficit of the health services sector within the district as well as spatial distribution The unbalanced situation that calls for intervention by the planning authorities to develop a clear and correct vision for the development of this sector. The research recommended the need for joint action by the executive and planning authorities to overcome the problems and to develop a clear strategy to extend the health sector within the Ishaqi district.

The Effect of Continuous Care Model on Blood Pressure and Quality of Life in Patients with Hypertension: A Randomized Clinical Trial.

Introduction: Hypertension is one of the most common diseases in all populations. Since people with hypertension have a lower quality of life (QoL) compared to healthy people, it is necessary to follow up these patients according to their conditions. This study aimed to investigate the impact of a continuous care model on blood pressure and QoL in hypertensive patients. Methods: Using a random sampling method, this randomized clinical trial (RCT) included 66 patients with hypertension referring to the clinic of Shahid Madani hospital in Tabriz, Iran in 2019. Data collection tools in this research were demographic information questionnaire, sphygmomanometer control device and stethoscope and Quality of Life questionnaire (The Short Form Health Survey-12, SF-12). The patients were randomly assigned into two groups of control and experimental. After the pre-test, the patients' needs in the experimental group were assessed and the problems were resolved. Then, the post-test was performed one month and two months after the intervention. Data analysis was performed using SPSS software version 13. Results: After the intervention, there was a significant difference in the QoL score and blood pressure in the experimental group. However, this difference was not significant in the control group. Conclusion: Results indicated that using a follow-up care model had a positive effect on the blood pressure and QoL of patients with hypertension. It is recommended that further studies examine the impact of the integrated care model on QoL in other chronic diseases.

Low Cost, Ease-of-Access Fabrication of Microfluidic Devices Using Wet Paper Molds.

Rapid prototyping methods enable the widespread adoption of microfluidic technologies by empowering end-users from non-engineering disciplines to make devices using processes that are rapid, simple and inexpensive. In this work, we developed a liquid molding technique to create silicone/PDMS microfluidic devices by replica molding. To construct a liquid mold, we use inexpensive adhesive-backed paper, an acetate backing sheet, and an off-the-shelf digital cutter to create paper molds, which we then wet with predetermined amounts of water. Due to the immiscibility of water and PDMS, mold patterns can be effectively transferred onto PDMS similarly to solid molds. We demonstrate the feasibility of these wet paper molds for the fabrication of PDMS microfluidic devices and assess the influence of various process parameters on device yield and quality. This method possesses some distinct benefits compared to conventional techniques such as photolithography and 3D printing. First, we demonstrate that the shape of a channel’s cross-section may be altered from rectangular to semicircular by merely modifying the wetting parameters. Second, we illustrate how electrical impedance can be utilized as a marker for inspecting mold quality and identifying defects in a non-invasive manner without using visual tools such as microscopes or cameras. As a proof-of-concept device, we created a microfluidic T-junction droplet generator to produce water droplets in mineral oil ranging in size from 1.2 µL to 75 µL. We feel that this technology is an excellent addition to the microfluidic rapid prototyping toolbox and will find several applications in biological research.

A Comparative Study for Material Selection in 3D Printing of Scoliosis Back Brace.

In recent years, many research studies have focused on the application of 3D printing in the production of orthopaedic back braces. Several advantages, such as the ability to customise complex shapes, improved therapeutic effect and reduced production costs place this technology at the forefront in the ongoing evolution of the orthopaedic sector. In this work, four different materials, two of them poly(lactic acid) (PLA) and two of them poly(ethylene terephthalate glycol) (PETG), were characterised from a thermal, mechanical, rheological and morphological point of view. Our aim was to understand the effects of the material properties on the quality and functionality of a 3D-printed device. The specimens were cut from 3D-printed hemi-cylinders in two different orientation angles. Our results show that PETG-based samples have the best mechanical properties in terms of elastic modulus and elongation at break. The PLA-based samples demonstrated typical brittle behaviour, with elongation at break one order of magnitude lower. Impact tests demonstrated that the PETG-based samples had better properties in terms of energy absorption. Moreover, 3D-printed PETG samples demonstrated a better surface finishing with a more homogenous fibre–fibre interface. In summary, we demonstrate that the right choice of material and printing conditions are fundamental to satisfy the quality and functionality required for a scoliosis back brace.

Application of PDCA Circulation Regulation Combined with Nursing Mark in Nursing Safety and Quality Regulation of Disinfection Supply Center.

Objective A case-control study was conducted to explore the application value of PDCA cycle regulation combined with nursing label in nursing safety and quality regulation in disinfection supply centers. Methods The medical staff in the disinfection supply center of our hospital from January 2020 to December 2020 and from January 2021 to December 2021 were included in the control group (routine nursing regulation, n = 13) and the research group (PDCA circulation nursing regulation, n = 13). The differences in quality evaluation, disinfection qualification, quality regulation effect, supply satisfaction, job satisfaction, safety awareness, and comprehensive operation skills of nursing staff were compared, and the application value of PDCA cycle regulation combined with nursing label in nursing safety and quality regulation of disinfection supply center was comprehensively analyzed. Results The quality score of nursing staff, and quality evaluation in the study group was significantly higher than that in the control group, and the difference was statistically significant (P < 0.05). The disinfection qualification rate of nurses in the research group was significantly higher, and the difference was statistically significant (P < 0.05). The effect of device quality supervision in the study group was significantly improved, and the difference was statistically significant (P < 0.05). The scores of various supervisions in the study group were significantly higher than those in the control group, and the difference was statistically significant (P < 0.05). The safety recognition ability, risk prevention awareness, service awareness, and theory and operation scores of nurses in the study group were significantly higher than those in the control group, and the difference was statistically significant (P < 0.05). The incidence of adverse events in the study group was lower, and the difference was statistically significant (P < 0.05). The satisfaction of the research group was significantly higher than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion In summary, the implementation of the PDCA cycle supervision method in the supervision of the sterile supply center in conjunction with the nursing logo is conducive to improving the quality of supervision and sterilization of all work aspects of the sterile supply center, reducing the occurrence of adverse nursing events and promoting the job satisfaction of nurses. In addition, it is conducive to standardizing the operational processes of staff, improving self-learning awareness enhancement, and improving work quality and efficiency.

Pelatihan Inspection Preventive Maintenance (IPM) Alat Cath Lab

Health equipment is a very crucial component in health services. In Indonesian Hospitals, the quality of medical devices is carried out by the Hospital Facility Maintenance Installation, which is abbreviated as IPSRS. Generally, IPSRS staff consists of human resources who have qualifications in Electromedical, Public Health, and Management qualifications. HR who carry out maintenance and repairs, hereinafter referred to as Preventive Maintenance Inspection (IPM) of medical devices, are HR with electromedical qualifications. Cath Lab is the latest technology in the medical world. Therefore, many electromedical technicians do not understand the latest developments in the Cath Lab IPM process. In order to prepare hospital services with quality Cath Lab tools, reliable human resources are needed in carrying out their HDI. For this reason, training on HDI from this Cath Lab equipment is needed. This HDI training was attended by 534 participants from all over Indonesia which was carried out through the Zoom Meetings Application. This training succeeded in increasing the ability of participants by 22.28% from the initial ability of 46.48% to 68.76%. The participants' satisfaction with the reliability of the resource persons, activity themes, communication, committee and media used in the training activities was 86.57% in the very satisfied category.

Cleaning Quality Control Management of Medical Equipment in Hospital Disinfection Supply Room Based on Smart Medicine.

With the continuous improvement of medical level, the demand for medical devices increases year by year, and it is necessary to track the quality and safety of medical devices. Establishing the cleaning quality control management of medical devices can not only reduce medical accidents and inhibit the spread of counterfeit or substandard medical devices but also help enterprises find the source of problems, determine the flow of the same batch of products, and warn relevant enterprises to take measures after the occurrence of problem products, and ultimately ensure the rights and interests of consumers. This study aims to study the cleaning quality control management of medical equipment in the hospital disinfection supply room based on smart medical care and proposes related concepts of smart medical care, as well as related theories of Internet of Things technology and medical equipment tracking system and related concepts of medical equipment cleaning. In this study, by comparing the cleaning compliance rates of the two groups of medical devices through smart medical care, it can be seen that 100% of the research group applying program-based management is significantly higher than 76.6% of the conventional management path. There was statistical significance in the data comparison between groups (P < 0.05). Therefore, programmatic management is more targeted than conventional management paths.

An insight into optical beam induced current microscopy: Concepts and applications.

Laser scanning optical beam induced current (OBIC) microscopy has become a powerful and nondestructive alternative to other complicated methods like electron beam induced current (EBIC) microscopy, for high resolution defect analysis of electronic devices. OBIC is based on the generation of electron-hole pairs in the sample due to the raster scanning of a focused laser beam with energy equal or greater than the band gap energy and synchronized detection of resultant current profile with respect to the beam positions. OBIC is particularly suitable to localize defect sites caused by metal-semiconductor interdiffusion or electrostatic discharge (ESD). OBIC signals, thus, are capable of revealing the parameters/factors directly related to the reliability and efficiency of the electronic device under test (DUT). In this review, the basic principles of OBIC microscopy strategies and their notable applications in semiconductor device characterization are elucidated. An overview on the developments of OBIC microscopy is also presented. Specifically, the recent progresses on the following three OBIC measurement strategies have been reviewed, which include continuous laser based single photon OBIC, pulsed laser based single photon OBIC, and multiphoton OBIC microscopy for three-dimensional mapping of photocurrent response of electronic devices at high spatiotemporal resolution. Challenges and future prospects of OBIC in characterizing complex electronic devices are also discussed. HIGHLIGHTS: Characterization of electronic device quality is of paramount importance. Optical beam induced current (OBIC) microscopy offers spatially resolved mapping of local electronic properties. This review presents the principle and notable applications of OBIC microscopy.

Automatic Defect Detection in Epitaxial Layers by Micro Photoluminescence Imaging

The early in-line detection of defects is a fundamental step in semiconductor manufacturing to ensure the device quality. Inspection techniques currently available can effectively detect large epitaxial defects causing morphological surface variations like stacking faults, while dislocations go undetected. Herein we introduce a new technology with enhanced machine learning analysis, based on contactless and non-destructive room temperature micro-photoluminescence imaging (micro-PL), for the detection and classification of defects in silicon epitaxial layers. With laboratory microscopy techniques we investigate the correspondence between different defect morphologies in micro-PL images and extended crystallographic defects. A good matching in terms of defect density is found between automatic micro-PL analysis and the standard laboratory analysis in an interval spanning from few defects/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> up to 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> defects/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .

Selective Area Heteroepitaxy of p-i-n Junction GaP Nanopillar Arrays on Si (111) by MOCVD

Gallium phosphide (GaP) is an important optical material due to its visible wavelength band gap and high refractive index. However, the bandgap of the thermodynamically stable zinc blende GaP is indirect, but wurtzite (WZ) structure GaP is direct bandgap. In this work, we demonstrate high-quality and dense GaP vertical nanopillar (NP) array directly on Si (111) substrates through selective area epitaxy (SAE) by MOCVD for the first time, through systemic studies of the effect of TMGa flow rate, growth temperature, and V/III ratio. Uniform GaP NPs are grown over a patterned <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$400\,\,\mu \text{m}\,\,\times 400\,\,\mu \text{m}$ </tex-math></inline-formula> area with 97.5% yield. Arrays of GaP vertical p-i-n NP diodes are demonstrated with a ideality factor and rectification ratio of 3.7 and 103, respectively. With the high yield of hexagonal structure and electrically proven device quality of GaP NPs through this growth method, this work represents a significant step in achieving GaP NP based optoelectronic devices, such as micro-LEDs emitting in the green wavelength range.

Design and implementation of the new Italian healthcare digital interoperable registry for implantable medical devices

AbstractNowadays, the role played by registries in monitoring and improving healthcare, including the quality of medical devices, is widely recognized. A well‐designed digital healthcare registry, in particular regarding data collection procedures and tools, can effectively support goals such as monitoring a (large) population subject to a specific condition, describing the natural history of diseases, supporting observational study methods, as well as evaluating the clinical effectiveness or cost effectiveness of healthcare products and services. This article describes the architecture of a new platform implementing a digital interoperable healthcare registry, the Italian Implantable Prostheses Registry (RIPI). One of the main goals of RIPI is to provide reliable and high‐quality data for monitoring surgery outcomes, performing survival analysis, assessing the safety of devices and procedures, and supporting the traceability of patients. The article focuses on the key aspects and choices that guided the design and implementation processes of the new platform. Most of the design choices came from specific requirements to fulfill, in particular concerning data quality, access policy, interoperability, extensibility and modularity. Overall, the article discusses the main challenges and the adopted solutions, proposing a design perspective and describing an experience of interest for computer scientists, engineers and practitioners, in particular in the area of healthcare information systems.