Equipment Quality Control Research Articles

Full Set of Equipment for Soil Compaction and Quality Control in Constructing Tall Hydroelectric Dams

Full Set of Equipment for Soil Compaction and Quality Control in Constructing Tall Hydroelectric Dams

Evaluation and Analysis of Cement Raw Meal Homogenization Characteristics Based on Simulated Equipment Models.

In recent years, the variability in the composition of cement raw materials has increasingly impacted the quality of cement products. However, there has been relatively little research on the homogenization effects of equipment in the cement production process. Existing studies mainly focus on the primary functions of equipment, such as the grinding efficiency of ball mills, the thermal decomposition in cyclone preheaters, and the thermal decomposition in rotary kilns. This study selected four typical pieces of equipment with significant homogenization functions for an in-depth investigation: ball mills, pneumatic homogenizing silos, cyclone preheaters, and rotary kilns. To assess the homogenization efficacy of each apparatus, scaled-down models of these devices were constructed and subjected to simulated experiments. To improve experimental efficiency and realistically simulate actual production conditions in a laboratory setting, this study used the uniformity of the electrical capacitance of mixed powders instead of compositional uniformity to analyze homogenization effects. The test material in the experiment consisted of a mixture of raw meal from a cement factory with a high dielectric constant and Fe3O4 powder. The parallel plate capacitance method was employed to ascertain the capacitance value of the mixed powder prior to and subsequent to treatment by each equipment model. The fluctuation of the input and output curves was analyzed, and the standard deviation (S), coefficient of variation (R), and homogenization multiplier (H) were calculated in order to evaluate the homogenization effect of each equipment model on the raw meal. The findings of the study indicated that the pneumatic homogenizer exhibited an exemplary homogenization effect, followed by the ball mill. For the ball mill, a higher proportion of small balls in the gradation can significantly enhance the homogenization effect without considering the grinding efficiency. The five-stage cyclone preheater also has a better homogenization effect, while the rotary kiln has a less significant homogenization effect on raw meal. Finally, the raw meal processed by each equipment model was used for clinker calcination and the preparation of cement mortar samples. After curing for three days, the compressive and flexural strengths of the samples were tested, thereby indirectly verifying the homogenization effect of each equipment model on the raw meal. This study helps to understand the homogenization process of raw materials by equipment in cement production and provides certain reference and data support for equipment selection, operation optimization, and quality control in the cement production process.

Evaluasi Kinerja Konsultan terhadap Manajemen pada Pekerjaan Ruas Jalan Lambaro - Pidie

The development project on the Lambaroe-Pidie national road is expected to be carried out according to plan. This can be realized with the role of a team of Project Management Consultants within the Aceh National Road Implementation Center who carry out construction management including implementation and control in program preparation, technical planning, construction implementation and supervision, quality control, service and supply of materials and equipment. The purpose of this research is to evaluate the factors that determine the effective performance of consultants and evaluate the performance indicators of consultants on management on the Lambaroe-Pidie national road section. The research method is a mixed method, which is a method that combines qualitative and quantitative methods. The sampling technique used is quotas. This research was conducted by distributing questionnaires to the owner, project officer, PT. Citra Diecona, Contractors and Technical Assistance Team (Bantek) with a total of 13 respondents. Questionnaire tests include validity tests and reliability tests. Based on the results of the study, the validity test obtained a value of Rcount > Rtable with a value of 0.552, this indicates that the question item is valid. In the reliability test, a value of 0.694 was obtained, this indicated that the respondents' answers were reliable. Based on the results of the descriptive analysis the initiative variable (X5) has the highest value of 4.692, this explains that the respondents are very satisfied with the consultant's performance on the initiative aspect. The ability to communicate (X2) has the lowest value with a mean value of 4.369. although this variable has the lowest mean, the results of the study show that respondents are satisfied with the consultant's performance on the communication aspect. The evaluation of the consultant's performance on management on the Lambaro - Pidie road section has met the road performance indicators in accordance with the 2017 Public Works Regulations concerning road performance indicators on management on the Lambaro - Pidie National Road section.

Design and Construction of a Radiochemistry Laboratory and cGMP-Compliant Radiopharmacy Facility.

The establishment of a compliant radiopharmacy facility within a university setting is crucial for supporting fundamental and preclinical studies, as well as for the production of high-quality radiopharmaceuticals for clinical testing in human protocols as part of Investigational New Drug (IND) applications that are reviewed and approved by the U.S. Food and Drug Administration (FDA). This manuscript details the design and construction of a 550 ft2 facility, which included a radiopharmacy and a radiochemistry laboratory, to support radiopharmaceutical development research and facilitate translational research projects. The facility was designed to meet FDA guidelines for the production of aseptic radiopharmaceuticals in accordance with current good manufacturing practice (cGMP). A modular hard-panel cleanroom was constructed to meet manufacturing classifications set by the International Organization of Standardization (ISO), complete with a gowning room and an anteroom. Two lead-shielded hot cells and two dual-mini hot cells, connected via underground trenches containing shielded conduits, were installed to optimize radioactive material transfer while minimizing personnel radiation exposure. Concrete blocks and lead bricks provided sufficient and cost-effective radiation shielding for the trenches. Air quality was controlled using pre-filters and high-efficiency particulate air (HEPA) filters to meet cleanroom ISO7 (Class 10,000) standards. A laminar-flow biosafety cabinet was installed in the cleanroom for preparation of sterile dose vials. Noteworthy was a laminar-flow insert in the hot cell that provided a shielded laminar-flow sterile environment meeting ISO5 (class 100) standards. The design included the constant control and monitoring of differential air pressures across the cleanroom, anteroom, gowning room, and controlled research space, as well as maintenance of temperature and humidity. The facility was equipped with state-of-the-art equipment for quality control and release testing of radiopharmaceuticals. Administrative controls and standard operating procedures (SOPs) were established to ensure compliance with manufacturing standards and regulatory requirements. Overall, the design and construction of this radiopharmacy facility exemplified a commitment to advancing fundamental, translational, and clinical applications of radiopharmaceutical research within an academic environment.

The role and application of high-throughput screening in the search for chemical compounds of therapeutic activity

With the development of medicine and the aging population, the demand for more effective therapies is escalating. A tool that facilitates the discovery and introduction of new therapeutic drugs is High-Throughput Screening (HTS). These tests, consisting of a wide set of various assays, allow testing hundreds of thousands of compounds in a short period of time. The aim is to accurately identify active compounds that could become potential therapeutic candidates in the pharmaceutical industry. HTS is the first step in the quest for potential drugs, therefore it is one of the crucial tests that determine whether a particular drug candidate will be discovered. In this review, different stages of high-throughput screening studies will be described, as well as methods utilized in these studies. The necessary steps in the optimization of these tests, selection of equipment, automation and key quality control parameters for reliably performed screening will also be presented.

The status of nuclear medicine in China: the first official national survey.

The National Nuclear Medicine Quality Control Center of China conducted the first official survey to investigate the nationwide situation of nuclear medicine in 2020. The survey aimed to unveil the current nuclear medicine situation and its quality control in China. The web-based survey was conducted and the data was collected via the National Clinical Improvement System (NCIS) of China from 1st April to 31st May 2021. A total of 808 institutes across 30 provinces responded to the national survey. For human resources, there are 4460 physicians, 3077 technologists, 339 physicists, and 309 radiochemists. There are 887 single-photon imaging instruments, including 823 SPECT or SPECT/CT, and 365 PET instruments including 314 PET/CT. Six hundred twenty-four institutes perform SPECT examinations and 319 institutes perform PET examinations. 60% of SPECT scans are bone scintigraphy. A total of 97% of PET scans use an [18F]F-FDG tracer. Furthermore, 587 institutes provide radionuclide therapy services but only 280 institutes have admission rooms. The top three radionuclide therapies are [131I] therapy of hyperthyroidism with 546 institutes, [89Sr] therapy of bone metastasis with 400 institutes, and [131I] therapy of differentiated thyroid cancer with 286 institutes. Finally, for the frequency of equipment quality control per year, there are about 67 times self-test within the department for SPECT instruments and 111 times for PET instruments on average in each province. There are about three failures of SPECT and five failures of PET on average per year in each province. There are 408 institutes (of 624 SPECT institutes) performing quality control of SPECT radiopharmaceuticals, 216 (of 319) for PET radiopharmaceuticals, and 373 (of 587) for radionuclide therapy. These results of the first official survey towards current status of nuclear medicine in China are the foundation for the establishment of the quality control management system.

EQUIPMENT AND DEVICES OF FOOD QUALITY CONTROL

This comprehensive research investigates the indispensable role of food quality control devices, including refractometers, pH meters, thermometers, and scales, in safeguarding the safety and integrity of the global food supply chain. The study meticulously elucidates the intricate functionalities, advantages, and limitations of these critical measuring instruments, underscoring the pivotal importance of their judicious selection for fostering sustainable and efficient food production practices. Notably, the research offers nuanced insights into crucial considerations such as the profound impact of temperature on refractometer readings, the efficiency factors inherent in pH meters, and the diverse types of thermometers tailored for specific applications within the food industry. The investigation goes beyond the mere exploration of equipment functionalities by delving into significant operational aspects. It addresses key factors like calibration, maintenance, and cleaning procedures, recognizing these as critical elements in ensuring the accuracy and reliability of food quality control processes. By conducting an exhaustive literature review, the research not only consolidates existing knowledge but also positions itself as a valuable resource for industry professionals, researchers, and policymakers engaged in the critical realms of food safety and quality assurance. Furthermore, this research seeks to fill gaps in understanding by contributing to a holistic understanding of the contemporary landscape surrounding food quality control and diagnostic equipment. As the findings are distilled from a diverse array of scholarly articles, scientific publications, and authoritative sources, the study underscores its commitment to promoting informed decision-making in the strategic selection and adept utilization of these essential tools. Ultimately, the research endeavors to transcend traditional academic boundaries, offering practical insights that can be directly applied to enhance food quality control measures and strengthen the robustness of the global food supply chain. Keywords:Quality control equipments, Refractometers, PH-meters, Thermometers, Scales.

Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)

Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)

PAM-based hydrogels characterization as a potential biomaterial for mammography QC-phantoms development

Hydrogels can mimic three-dimensional characteristics of human tissues, which can be used to evaluate diagnostic X-ray equipment quality control features. In this study, polyacrylamide hydrogels (PAM) with different polymer concentrations were synthesized and displayed a light-cloudy to milky-white appearance. Synthesis was confirmed by FTIR, and absorbance properties were analyzed by UV-VIS spectroscopy. SEM micrographs, tomographic and mammography images of PAM-hydrogels showed that matrix porous size, Hounsfield Units (6.47–26.33), and Mean Pixel Value (1144.70–2458.20) could be tunable via swelling process, with a maximum swelling of ∼288.11%. Thus, PAM-hydrogels can mimic human-tissue characteristics useful for X-ray phantoms development.

A Study on the Uncertainty of the Average Glandular Dose in Quality Control of Mammographic X-ray Units

【Purpose】 Accurate control of X-ray units and dosimeters and analysis of the uncertainties associated with the accurate measurement of radiation doses are essential for the effective establishment and application of diagnostic reference levels. In this study, the uncertainty of the average glandular dose (AGD) in the quality control of mammography equipment was evaluated in detail, and recommendations were provided to improve the accuracy and safety of radiological practice. 【Methods】 In the uncertainty analysis of the AGD, the relative standard uncertainties in the measurements of the half-value layer, the incident air kerma, and the conversion factor were considered and finally expressed as expanded uncertainties, the intervals of which were clearly defined. 【Results】 From the AGD measurements using two types of dosimeters, it was found that the primary sources of uncertainty are the uncertainty of the calibration factors of the dosimeters and the uncertainty of the conversion factors.【Conclusion】 To reduce uncertainty, the use of regularly calibrated dosimeters is effective and reliable. Two types of dosimeters are commonly used; the results of this study may serve as a reference value for the uncertainty of AGD in quality control in medical facilities.

The Use of AI Technology in Digital Ceramic Technology

Abstract With the development of AI technology, the development of the ceramic industry has ushered in a good opportunity. This paper discusses the application of AI technology in the field of ceramics on the basis of deep convolutional generative adversarial network, using Adam optimizer to further improve the performance of the model, using the hidden space to add noise to each layer of the network, and proposing a digital ceramic texture image generation model based on DCGAN. Meanwhile, the K-Means algorithm and feature fusion mechanism with BWP as the evaluation index are introduced to improve the Faster R-CNN algorithm and construct the ceramic defect detection model. The scores of each subjective evaluation index of image generation quality are greater than 4, which are located in the interval of higher evaluation. The scores of IS, BRISQUE, and NIQE are 3.39, 22.57, and 4.43, and the quality of ceramic texture image generation of this paper’s model is better than that of other algorithms. The ceramic defect detection model’s detection accuracy for all five ceramic defects is higher than 92.68%, with an 8.54% improvement over the original algorithm’s defect detection performance. The research in this paper has important theoretical and practical significance for ceramic product design, quality control, and troubleshooting of production equipment.

Optimización de una bebida con exudado de cacao Theobroma cacao L. CCN51 y suero láctico usando superficie respuesta

The aim of this research was to characterize rheologically a drink formulated and elaborated with exudate of cocoa (Theobroma cacao L.) CCN51 and lactic serum. The formulation was optimized using the response surface methodology for the attributes color, smell, taste and acceptability; subsequently, a multiple surface analysis was performed to determine the global optimal parameters by means of the desirability function. The results ensure that the proportion exudate and lactic serum should be 40/60 with 10% sucrose. The rheology of the beverage shows that it is a non-Newtonian fluid of the pseudoplastic type. In general, temperature and storage time have a significant effect on the flow index and consistency index. The proximal and microbiological chemical tests meet the standards, and the drink is suitable for human consumption. The rheological results of drinks based on cocoa exudate and lactic whey can be used as a parameter for quality control and sizing of machines, equipment, pipes, connections, filters, drive pumps and research provide knowledge for the use of agro-industrial residue. and the dairy industry.

FLOW PATTERN PREDICTION IN HORIZONTAL AND INCLINED PIPES USING TREE-BASED AUTOMATED MACHINE LEARNING

In the oil and gas industry, understanding two-phase (gas-liquid) flow is pivotal, as it directly influences equipment design, quality control, and operational efficiency. Flow pattern determination is thus fundamental to industrial engineering and management. This study utilizes the Tree-based Pipeline Optimization Tool (TPOT), an Automated Machine Learning (AutoML) framework that employs genetic programming, in obtaining the best machine learning model for a provided dataset. This paper presents the design of flow pattern prediction models using the TPOT. The TPOT was applied to predict flow patterns in 2.5 cm and 5.1 cm diameter pipes, using datasets from existing literature. The datasets went through handling of imbalanced data, standardization, and one-hot encoding as data preparation techniques before being fed into TPOT. The models designed for the 2.5 cm and 5.1 cm datasets were named as FPTL_TPOT_2.5 and FPTL_TPOT_5.1, respectively. A comparative analysis of these models alongside other standard supervised machine learning models and similar state-of-the-art similar two-phase flow prediction models was carried out and the insights on the performance of these TPOT designed models were discussed. The results demonstrated that models designed with TPOT achieve remarkable accuracy, scoring 97.66% and 98.09%, for the 2.5 cm and 5.1 cm datasets respectively. Furthermore, the FPTL_TPOT_2.5 and FPTL_TPOT_5.1 models outperformed other counterpart machine learning models in terms of performance, underscoring TPOT’s effectiveness in designing machine learning models for flow pattern prediction. The findings of this research carry significant implications for enhancing efficiency and optimizing industrial processes in the oil and gas sector.

Pelaksanaan Quality Control Pesawat Sinar X di Pelayanan Radiodiagnostik

Background: Quality Control can be used as a monitoring of the reliability of X-Ray Unit during the validity period of the Conformity Test Certificate. During the use of X-ray Unit, there is the potential for damage to components during the validity period of the certificate of passing the Compliance Test. If the X-Ray Unit Reliability Test is only carried out during the Compliance Test, then if there is a decrease in the quality and safety of the X-ray Unit it cannot be immediately known. This has the potential to endanger patients, radiation workers and the public. In Banyumas Regency, there are 80 Radiation Source Utilization Permits spread across 34 radiodiagnostic installation. Preliminary studies show that not all radiodiagnostic installation carry out routine X-ray machine reliability tests according to the Keputusan Menteri Kesehatan Republik Indonesia Nomor 1250/Menkes/SK/XII/2009 Tentang Pedoman Kendali Mutu (Quality Control) Peralatan Radiodiagnostik.
 Method: This research type is qualitative with survey of 20 radiodiagnostic installation using a questionnaire instrument. Quality control conducted periodically includes kVp accuracy test, linearity and reproducibility mA, exposure time accuracy test, tube leak test, collimator beam suitability test, collimator shutter efficiency test, collimator light strength test, HVL measurement, implementation of reject analysis program and availability and qualifications of quality control officers and availability of quality control equipment. Then the data will be grouped based on research objectives and presented descriptively.
 Result: From the results of data collection, 1 hospital did not have a quality control officer and 4 hospitals had a quality control officer with an educational background of Diploma IV in Radiology Engineering without any Radiology Equipment Quality Control training. Meanwhile, 15 hospitals have quality control officers with an educational background in the Medical Physics Undergraduate Program and have attended training in Quality Control of Radiology Equipment. Of the 20 hospital radiology installations, there were 7 hospitals that did not carry out the Reject Analysis Program. This was done with the assumption that Digital Radiography had been used in both the CR and DR modalities. A number of 13 hospitals continued to carry out the Reject Analysis Program even though they had used Digital Radiography. Of the 20 hospital radiology installations, there are 6 hospitals that independently carry out X-ray unit testing within the framework of a quality control program. However, only 1 hospital conducts regular testing. Testing is also limited to the accuracy of the collimator field and the strong light of the collimator. Fourteen hospitals did not carry out a quality control program independently but only carried out an X-ray unit calibration test once a year which was carried out by BPFK and an X-ray unit distributor company.
 Conclusion: The implementation of quality control of x-ray machines on a regular basis has not been carried out by all radiodiagnostic services, even though they already have quality control officers. One of the reasons is the availability of quality control equipment needed for testing and supervision of radiodiagnostic service management. The role of management of radiodiagnostic services is needed to overcome these problems.
 
 Keyword : Quality Control Programe, Compliance Test, X-Ray Unit

Quality audits of nuclear medicine practices in a middle-income African setting.

The International Atomic Energy Agency (IAEA) introduced a Quality Management Audits in Nuclear Medicine (QUANUM) programme, to improve nuclear medicine practice standards aligned with international standards through self-assessments. The absence of quality management audits in nuclear medicine departments could potentially result in a compromise in the safety and quality of patient care. To date, there is no evidence that quality audits have been conducted in nuclear medicine departments of this middle-income country. This quality audit, therefore, assessed conformance to the IAEA QUANUM programme in four nuclear medicine departments. The study adopted a quantitative methodological exploratory approach. The IAEA QUANUM programme was used to audit nuclear medicine services' overall activity such as clinical practice, management, radiopharmacy, general and radiation safety, quality assurance, operations and services. The data was collected via document analysis in four nuclear medicine department identified as Sites A-D. Overall results showed that Site A conformed with 247 out of 370 (67%) counts and non-conformed with 123 out of 370 (33%) counts whilst Site B conformed with 205 out of 342 (60%) counts and non-conformed with 137 out of 342 counts (40%). Site C conformed with 259 out of 345 (75%) counts and non-conformed with 86 out of 345 (25%) counts. Site D conformed with 166 out of 349 (48%) counts and non-conformed with 183 out of 349 (52%) counts. The study yielded 125 overall recommendations. All the sites demonstrated good compliance to international standards in radionuclide therapy. Site A complied poorly in strategies and policies, whilst Site B complied poorly in quality control of equipment. Site C showed poor compliance to human resource development and Site D showed aspects pertaining to administration and management as well as evaluation of quality systems.

Improved Decal Transfer Method to Reduce Membrane Damage from Foreign Particles in Membrane Electrode Assembly

Foreign particles unintentionally embedded in the membrane electrolyte assembly may be detrimental to polymer electrolyte fuel cell durability by dissolution of contaminants or puncture of the membrane. The presence of incidental particles may also affect the fuel cell production cost by imposing more stringent and costly quality control equipment and cleanroom facilities to the manufacturers. The present work aims to understand the impact of foreign particles deposited at the membrane—catalyst layer interface on the decal transfer process and the quality of the resulting catalyst coated membrane. Additionally, this work explores process related opportunities to mitigate material damage from said particles. Several samples are fabricated by specifically placing representative silica particles on the membrane surface subsequently laminated with catalyst layer using different decal transfer procedures. Non-destructive 3D X-ray computed tomography reveals that the model particles substantially penetrate the membrane during regular decal transfer conditions, leading to a vulnerable membrane state or even complete puncture. However, a tuned decal transfer method with modified pressure application rate and optimized supporting layers is shown to reduce membrane damage up to 69%. Additionally, finite element modeling shows that the tuned method can reduce membrane stress during fuel cell operation and thus benefit durability.

ENVIRONMENTALIZATION OF HOTEL AND RESTAURANT BUSINESS

The aim of this article is to summarize and methodize the current information about ecological problems of hotel and restaurant sector, including Ukraine; to identify the main principles with the aim of ecologization of this tourism component based on world experience. Due to the current state of the world, Covid‑19 eco-friendly hotels are also in a good position. Greening is an added security health. Organic cuisine supports strong immunity. Natural and hypoallergenic materials in the hotel equipment have only a positive effect on the human body. Landscaping and interior landscaping spacious rooms provide cleaner air and favorable conditions for living, wellness, and rest. Worsening factors have emerged environmental indicators (increase in waste, mandatory individual packaging, etc.). The current state of hotel activities has led to the search for new one’s environmental measures and development strategies. In recent decades, the hotel business in Ukraine has been developing dynamically. Significant changes have been made for account of entering the market of hotel services of international networks such as Rixos, Rezidor, Hyatt, Wyndham Hotel Group. The policy of their activities contributed adjustments to the competitive position of the industry. Signs efficient hotel facility is a high level and quality control of services, environmental orientation, modern equipment and innovative technologies.

Vitro UPLC analysis and mass method identification, and in vivo or cellular immune anti-inflammatory function of Sanhuang Xiexin Decoction (SHXD)

Ethnopharmacological relevanceSanhuang Xiexin Decoction (SHXD), consisting of Coptis chinensis Franch., Scutellaria baicalensis Georgi and Rheum palmatum L., is traditionally used for relieving fever, purging fire for removing toxins, eliminating phlegm and haemostasis, eliminating the wetness-evil from the upper warmer, clearing away the heat-evil and expelling superficial evils. Each of the three herbs contained in SHXD has been indicated to have anti-inflammatory effects in vivo, but its effects on rat NK-cell phenotypes remain unexplored, and the comprehensive mechanism of this compound SHXD in curing the inflammation induced by lipopolysaccharides (LPS) remains to be revealed. Aim of the studyThe study aim was to assess the effect of SHXD on LPS-induced fever and inflammation in a rat model, reduce NLRP3 activation in NK cells expressing specific cell phenotype antibodies and determine the therapeutic value of this approach in vivo. Materials and methodsSHXD extract was prepared and analysed by the developed ultra-performance liquid chromatography (UPLC) method for the simultaneous detection of 14 compounds. The main peaks were firstly identified on an Orbitrap via high resolution tandem mass spectrometry (MS). Then, the extract was used in the rat model of LPS-induced inflammation and fever for pharmacologically study the effects of drug treatment. Peripheral blood lymphocyte cells were isolated from the animals, including those subjected to the SHXD extract treatment, and the cell phenotype was determined prior to cell culture and after treating the cell cultures with the extract. The phenotypes of cells harvested using CD3, CD4, CD8a, CD81, CD161 and CD86 antibodies were used to verify the enhanced memory of the peripheral blood lymphocytes cells (PBMC) that were induced into nature killer (NK) cells. ResultsThe SHXD extract was prepared, analysed and identified via quality control equipment and was observed to have pharmacological effects that reduced NLRP3 activation and fever in rats. The production of NK cells and peripheral blood lymphocytes was induced by the SHXD extract, which manifested as increased levels of CD4+, CD8a+, CD81+, CD161+ and CD86+ cells. The levels of CD3+ cells were significantly different between the model group and the drug-treated or control groups (p < 0.01) with dose independence, while the levels of CD4+ cells were not significantly different between the drug-treated and control groups, with a trend towards lower levels in the model group with dose independence. The levels of CD4+ cells was significantly different between the drug-treated group and the model groups with dose independence (p < 0.05). The levels of CD86+ cells were not significantly different between the drug-treated group and the model and control groups. The levels of CD8a + cells was significantly different between the model group and the drug and control groups (p < 0.05, dose 2.0 μg/ml), with higher levels in the drug-treated group. The levels of CD3+, CD4+, CD8a + cells in the drug treated group have dose dependence with SHXD. ConclusionsThis experiment revealed that SHXD reduced NLRP3 activation in the blood of LPS-treated rats, which occurred through the activation of NK cells that expressed CD3, CD8a and CD161. SHXD may possess anti-inflammatory effect via activacting the one of major pharmacology effcet of NK cells that expressed CD3, CD8a and CD161 phenotypes expression. This result demonstrates that SHXD may possess ability to enhance the memory of peripheral blood lymphocytes and natural killer cells.

European Respiratory Society/American Thoracic Society technical statement: standardisation of the measurement of lung volumes, 2023 update.

This document updates the 2005 European Respiratory Society (ERS) and American Thoracic Society (ATS) technical standard for the measurement of lung volumes. The 2005 document integrated the recommendations of an ATS/ERS task force with those from an earlier National Heart, Lung, and Blood Institute workshop that led to the publication of background papers between 1995 and 1999 and a consensus workshop report with more in-depth descriptions and discussion. Advancements in hardware and software, new research and emerging approaches have necessitated an update to the 2005 technical standard to guide laboratory directors, physiologists, operators, pulmonologists and manufacturers. Key updates include standardisation of linked spirometry, new equipment quality control and validation recommendations, generalisation of the multiple breath washout concept beyond nitrogen, a new acceptability and grading system with addition of example tracings, and a brief review of imaging and other new techniques to measure lung volumes. Future directions and key research questions are also noted.

Measurement and Testing and Quality Control of Medical Equipment in Medical Institutions

Measurement and Testing and Quality Control of Medical Equipment in Medical Institutions