Abstract

Hydrogels can mimic three-dimensional characteristics of human tissues, which can be used to evaluate diagnostic X-ray equipment quality control features. In this study, polyacrylamide hydrogels (PAM) with different polymer concentrations were synthesized and displayed a light-cloudy to milky-white appearance. Synthesis was confirmed by FTIR, and absorbance properties were analyzed by UV-VIS spectroscopy. SEM micrographs, tomographic and mammography images of PAM-hydrogels showed that matrix porous size, Hounsfield Units (6.47–26.33), and Mean Pixel Value (1144.70–2458.20) could be tunable via swelling process, with a maximum swelling of ∼288.11%. Thus, PAM-hydrogels can mimic human-tissue characteristics useful for X-ray phantoms development.

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