The Back Propagation (BP) neural network model is one of the neural network models suitable for model recognition and classification. However, a single BP network model cannot fully tap the feature information hiding in the data and is vulnerable to the uncertainty associated with system parameter changes and also suffers from the effects of long diagnosis times, inaccurate and undesired diagnosis results in applying a large amount of high-dimensional feature data. In addition, the standard BP algorithm has limitations in pattern recognition and classification. For example, it adopts the quadratic cost function to train the neural network, which can lead to low convergence accuracy, low convergence rate, and so on. Compared with the quadratic cost function, the cross-entropy cost function can effectively improve the convergence accuracy and the convergence rate of the neural network. The Dempster–Shafer (D–S) evidence theory is a powerful tool for handling incomplete, imprecise, and uncertain information and merging it when it derives from multiple BP networks. In order to overcome the drawbacks of a single BP network, it is necessary to divide the high-dimensional feature data into several different categories of low-dimensional feature data and to input the same dimensional feature data into the same BP network model, as well as to design the information fusion algorithms based on D–S evidence theory and multiple improved BP networks with the cross-entropy cost function. For this reason, this paper proposes a novel information fusion diagnosis approach based on D–S evidence theory and multiple improved BP networks for fault diagnosis and classification of multiple devices in a ballast system subjected to extreme environmental conditions. The proposed diagnosis approach utilizes multiple neural networks to carry out local fault diagnosis, adopts the D–S evidence theory to fuse the results of local diagnosis and derive the decision results, and introduces an improved BP algorithm based on the cross-entropy cost function into the individual neural networks to enhance the convergence rate and diagnosis accuracy of the individual neural networks. This method can overcome the deficiencies of individual BP networks in multiple BP networks in their poor diagnostic ability to handle incomplete, imprecise, and uncertain sample information. According to the design idea of the proposed diagnosis approach, a new fusion modeling for fault diagnosis of multiple devices is constructed for a ballast system. The validity of the proposed diagnosis method and model is illustrated through both simulation studies and experimental tests.