Pyogenic Granuloma Research Articles

Conjunctival fibroepithelial polyp – A rare case

Fibroepithelial polyp, one of the most common benign cutaneous lesions, was seen as a conjunctival mass, which, to the best of our knowledge, is the second ever reported case of fibroepithelial polyp involving conjunctiva, although it can have atypical presentation and has been reported at sites like ureteropelvic junction, genitals, bronchi, tonsils, and outer ear canal. The common benign and malignant conjunctival lesions are pterygium, pingecuela, pannus, pyogenic granuloma, limbal dermoid, papilloma, squamous cell carcinoma, lymphoma, Kaposi sarcoma, and malignant melanoma. Therefore, the possibility of fibroepithelial polyp affecting uncommon sites cannot be negated.

Acrodermatitis Continua of Hallopeau: A Diagnostic Challenge.

Acrodermatitis Continua of Hallopeau: A Diagnostic Challenge.

Lobular capillary hemangioma of nasal septum after comprehensive treatment of adenoid cystic carcinoma of nasal cavity

Lobular capillary hemangioma of nasal septum after comprehensive treatment of adenoid cystic carcinoma of nasal cavity

Management of Nasal Lobular Capillary Hemangioma with Sunitib

Management of Nasal Lobular Capillary Hemangioma with Sunitib

Management of liver clot following surgical excision of a recurrent pyogenic granuloma: A case report

Management of liver clot following surgical excision of a recurrent pyogenic granuloma: A case report

A case of a rapidly growing pyogenic granuloma.

A case of a rapidly growing pyogenic granuloma.

Treatment of recurrent pyogenic granuloma: Case report with 1.5-year follow-up

Treatment of recurrent pyogenic granuloma: Case report with 1.5-year follow-up

Ibrutinib-Associated Multifocal Paronychia with Periungual Pyogenic Granulomas Involving Concomitant Finger and Toe Nails.

Ibrutinib-Associated Multifocal Paronychia with Periungual Pyogenic Granulomas Involving Concomitant Finger and Toe Nails.

Pyogenic Granuloma of the Vermillion: Surgical Treatment of Lip Vermilion, and its Outcomes

Pyogenic Granuloma of the Vermillion: Surgical Treatment of Lip Vermilion, and its Outcomes

Lingual location of Sweet's syndrome: A case report

Context: Sweet's syndrome is a rare acute febrile neutrophilic dermatosis and idiopathic in two-thirds of cases. The pathophysiological mechanisms of Sweet's syndrome are poorly understood. Observation: A 35 yr old female patient has been referred from the Dermatology Department to the Oral and Surgery Department, University Hospital Center of Oran (Algeria), for a lingual nodule. For medical history, the patient had a Sweet's syndrome diagnosed 1 yr ago and a rheumatoid arthritis treated with corticosteroids. An excisional biopsy of the lingual nodule was performed and the anatomopathological result revealed a pyogenic granuloma associated with polymorphonuclear neutrophilic vasculitis in the context of Sweet's syndrome. Discussion and conclusion: Sweet's syndrome is characterized by a constellation of clinical symptoms, biological and histological abnormalities and is manifested by the sudden appearance of painful skin lesions in the form of asymmetric erythematous papules, nodules or plaques. In the context of Sweet's syndrome, faced with an oral with cutaneous lesions a correlation and/or manifestation of neutrophilic dermatosis must be suspected.

Interdental Pyogenic Granuloma with Ossification in a Pediatric Patient - A Rare Case Report and a Mini Literature Review

Pyogenic granuloma is an acquired benign proliferation of capillary blood vessels of the skin and oral cavity.Ossification in Pyogenic Granuloma is an uncommon pathology that is linked with the possible etiopathogenesis of irritation and foreign body reaction. A 12-year-old female patient reported a chief complaint of gingival growth in the upper right back teeth region, which was initially small in size and eventually grew to attain the present size in 2 months. Clinical examination revealed a painless pinkish pedunculated growth of approximately 1.5x1 centimetre superior-inferiorly and media-laterally. The histopathological examination of the excised lesion revealed an unlikely diagnosis of pyogenic granuloma with ossification. The rarity of the lesion can be attributed to the possible irritation to the tooth-supporting structures caused by rotation of the premolar. Also, ossification seen within the lesion adds to the dilemma. This case report presents a rare case of a gingival pyogenic granuloma in the interdental region adjacent to the rotated maxillary second premolar. It may have a possible etiology of trauma to interdental periodontal fibres caused by rotation of premolars due to disturbances during development.

Clinical, Dermoscopic, Ultrasonographic, and Histopathologic Correlations in Kaposi's Sarcoma Lesions and Their Differential Diagnoses: A Single-Center Prospective Study.

(1) Background: Kaposi's sarcoma (KS) is an angioproliferative neoplasm typically appearing as angiomatous patches, plaques, and/or nodules on the skin. Dermoscopy and ultrasonography have been suggested as an aid in the diagnosis of KS, but there is little evidence in the literature, especially regarding its possible differential diagnoses. Our aim is to describe and compare the clinical, dermoscopic, and ultrasonographic features of KS and KS-like lesions. (2) Methods: we conducted a prospective study on 25 consecutive patients who were first referred to our tertiary care center from January to May 2021 for a possible KS. (3) Results: 41 cutaneous lesions were examined by means of dermoscopy, Doppler ultrasonography, and pathology, 32 of which were KS-related, while the remaining 9 were lesions with clinical resemblance to KS. On dermoscopy, a purplish-red pigmentation, scaly surface, and the collarette sign were the most common features among KS lesions (81.3%, 46.9%, and 28.1%, respectively). On US, all 9 KS plaques and 21 KS nodules presented a hypoechoic image. Dermoscopic and Doppler ultrasonographic findings of KS-like lesions, such as cherry angioma, venous lake, glomus tumor, pyogenic granuloma, and angiosarcoma were also analyzed. (4) Conclusions: dermoscopy and Doppler ultrasonography can be useful to better assess the features of KS lesions and in diagnosing equivocal KS-like lesions.

Sinonasal Lobular Capillary Hemangioma After Continuous Self-tests for COVID-19: A Case Report and Review of the Literature

Sinonasal lobular capillary hemangiomas (LCH) are rare benign vascular lesions commonly arising from the nasal septum. Nasopharyngeal, nasal mid-turbinate, and anterior nasal swabbing is the preferred method of screening for coronavirus disease-2019 (COVID-19). Herein, we present a case of a sinonasal LCH in a child after continuous self-tests for COVID-19, with an anterior nasal swab. The child presented with a well-defined red mass in the anterior part of the nasal septum, which was removed endoscopically. Histopathology revealed a LCH. This is the first report of a complication other than epistaxis with the use of an anterior nasal swab. Our literature review identified 32 studies reporting complications of COVID-19 screening. Cerebrospinal fluid leaks and foreign body retention are the most common ones. A proper specimen collection technique and a quick patient history with an emphasis on risk factors are the best practices to prevent complications from COVID-19 screening.

Oral kavitede kitle ve eşlik eden insidental papiller tiroid karsinomu ile başvuran normokalsemik primer hiperparatiroidizm olgusu

Hyperparathyroidism (HPT) is an endocrine disorder characterized by high secretion of parathyroid hormone. Brown tumor is one of the skeletal manifestations of HPT. Its overall prevalence is low (about 0.1%). Involvement of facial bones is extremely rare. The mandible is involved in 4.5% of cases. Primary HPT (PHPT)with vitamin D deficiency worsens the clinical course. Parathyroid adenoma is detected in ectopic places with a rate of 8.5%. 0.2% is intrathyroidal, 2% is located in different neck regions, 4.1% is in the upper mediastinum, and 2.2% is in the lower mediastinum. The prevalence of papillary thyroid cancer (PTC) in PHPT patients has been reported to range from 2% to 15%. In the literature, incidentally detected papillary thyroid cancer in patients with hyperparathyroidism was detected in patients who underwent total thyroidectomy associated with intrathyroidal parathyroid adenoma.
 In this article, we present a case of incidental papillary thyroid carcinoma with ectopic parathyroid adenoma accompanied by severe vitamin D, and diagnosed during accompanying surgery following a brown tumor was considered after primary hyperparathyroidism was detected. However, the patient was admitted with a mass in the oral cavity, diagnosed before as a pyogenic granuloma with a delayed diagnosis without considering brown tumor because it was normocalcemic. It is the first case in the literature of papillary thyroid carcinoma detected incidentally with ectopic parathyroid adenoma in the thyrothymic region.

Nasal lobular capillary hemangioma: etiologic factors

<p class="abstract">Nasal lobular capillary hemangioma (LCH) is a rare and benign vascular tumor of unknown etiology, often associated with hormonal factors and a history of trauma. In this case series we present twelve cases of nasal LCH diagnosed on patients treated at the Hospital da Senhora da Oliveira from January 2010 and December 2019. Of the 12 patients, 66, 7% were males. The most common clinical presentation was epistaxis (75%) followed by nasal obstruction (50%). In 75% of patients the most commonly affected area was the nasal septum. Regarding proposed contributing factors, nasal trauma was the most prevalent (33%), followed by the use of oral contraceptives (25%) and pregnancy (8.3%). Endoscopic sinus surgery was performed in all patients, with complete excision of the lesion, and no post-operative complications were observed. Nasal LCH should be considered in the differential diagnosis of nasal vascular lesions associated with unilateral epistaxis and nasal obstruction. Complete surgical resection should be the treatment of choice, since it’s associated with lower risk of recurrence.</p>

Pyogenic Granuloma of the Oral Cavity: Clinical and Histopathological Features, Etiopathogenesis, and Management

Pyogenic granuloma (PG) is a benign vascular tumor that usually occurs on the skin and mucous membranes, mostly of the oral cavity. The most common site for oral PG is the gingiva. The lesion arises in response to various stimuli, such as low-grade local irritation, traumatic injury, or hormonal changes. It may occur at any age, with the highest incidence in the 2nd and 5th decades of life. Women are more frequently affected due to the increased levels of circulating hormones like estrogen and progesterone. This article reviews the clinical and histopathological features of oral PG, as well as its etiopathogenesis, differential diagnosis, and treatment.

A case report of rare occurance of pyogenic granuloma at an unusual site – Mapping of its diagnosis and treatment plan

Pyogenic granuloma is an acquired, benign, common, non-neoplastic, and vascular reactive lesion, occurring in the oral cavity. It is a localized granulation tissue overgrowth symbolizing an exuberant tissue reaction to a trauma or local irritation. Regardless the name, the condition is not accompanied with pus discharge or formation of granuloma; therefore, the term “pyogenic granuloma” is a misnomer. It shows a striking predilection for gingiva though it may occur extragingivally on the tongue, lips, buccal mucosa, or palate. Herein, we describes a case report of pyogenic granuloma at an uncommon location on the upper lip in a male patient aged 40 years.

Mediastinal Lobular Capillary Haemangioma in Children with Severe Airway Obstruction Symptom: A Case Report

Background: Lobular capillary haemangioma (LCH) is a polypoid form of capillary haemangioma occurring on the skin and mucosal surfaces. While LCH of the oral and nasal cavity is well-known entity, mediastinal localization is a rare case. In children, LCH is frequently benign. Case illustration: A two month age baby girl experienced recurrent inspiratory stridor since she was 42 days-old and diagnosed as laryngomalacia. Due to the widening of mediastinal area from chest x-ray, a chest CT-scan was conducted and showed a mass in the mediastinal area. A sternotomy was done and found mass filled the mediastinal space. Some parts of the mass found to depress the trachea. Mediastinal tumor resection procedure done. A definitive pathology anatomy result was a lobular capillary haemangioma. After surgery, stridor gradually improves. Summary: We reported this rare mediastinal lobular capillary haemangioma case that was initially diagnosed with laryngomalacia After removal of the tumor, the stridor gradually improved. Keywords: Lobular capillary haemangioma, pyogenic granuloma, mediastinal tumor, stridor, children

Oral Juvenile Xanthogranuloma: a case report of gingival hyperplasia and osteolysis in male adult patient

BackgroundJuvenile Xanthogranuloma (JXG) is a non-hereditary, self-limiting disease which is usually presented in infancy or early childhood and in males over females.Case presentationWe report a rare case of oral Juvenile Xanthogranuloma with recurrent progressive gingival hyperplasia and concomitant presentation of osteolysis in a 21-year-old adult male with no significant medical history. Patient presented with generalized gingival hyperplasia, osteolysis of the maxilla and mandible, and a round, firm, nodular mass with clear circumference on the left shoulder. Results of gingival tissue biopsy, karyotype, bone marrow biopsy and immunohistochemistry were suggestive of a diagnosis of Juvenile Xanthogranuloma with no association to hematologic malignancy. Unfortunately, patient declined treatment and elected to be transferred back to local hospital for future evaluation.ConclusionsJuvenile Xanthogranuloma in adults can have atypical manifestations including generalized gingival hyperplasia and osteolysis of the maxilla and mandible. It should be differentiated between Langerhans cell histiocytosis, Papillon–Lefevre Syndrome, and Pyogenic Granulomas. Despite uncommon incidence, it should be included in differential diagnoses in cases of similar clinical presentations.

A hyperplastic growth of lip

A 25- year-old systemically healthy female patient reported with an aesthetic complaint due to a growth in the corner of right upper lip present for 2 months. Clinical examination revealed a solitary spherical-shaped bright red fibrous overgrowth measuring 4x4 mm involving the mucocutaneous line of upper lip (Figure 1A & B). On palpation, it was non tender, smooth in texture, and soft in consistency. Based on the signs and symptoms, a provisional diagnosis of fibroma was made with a differential diagnosis of pyogenic granuloma. After obtaining written informed consent, the lesion was excised in totowith 1 mm of healthy margin by performing two elliptical incisions (Figure 1C). The biopsied tissue was fixed in 10% formalin and sent for histopathological examination. Double-layered microsurgical suturing was done with 7-0 polyglactin suture (Figure 1D) followed by superficial suturing of the wound margins (Figure 1E). Postoperative instructions were given and analgesics were prescribed, as and when required. Healing was uneventful and sutures were removed at 10 days follow-up (Figure 1F). A good cosmetic outcome and high patient satisfaction was achieved at 3 months (Figure 1G & H).