Electroosmosis peristaltic flows find promising applications in electro-fluid thrusters in space propulsion, polymer injection systems, ion exchange membrane designs, microbe fuel cells, biochip fabrication and fossil fuel energy process. In light of this, the current work aims to investigate blood based electroosmotic peristaltic flow in a ciliated, non-uniform propagation channel when copper nanoparticles are present. For that purpose, mathematical modeling is done in two dimensional frame and then governing partial differential equations are simplified and converted in ordinary differential equations using dimensionless quantities and long wave length and low Reynolds number approximations. In result we got coupled nonlinear boundary value problem that is solved numerically using three-stage Lobatto IIIa formula known as bvp4c invoking shooting technique. Peristaltic ciliated waves are thought to pass along the channel wall. The properties of both fluid phase and particle phase flow are modeled and investigated. Plotting against various parameters, streamline contours, temperature contours, concentration and temperature profiles, and pressure rise graphs are examined in-depth from a physical perspective. The obtained results revealed that concentration profile α upsurges for rising values of Casson fluid parameter β, nanoparticle volume fraction ϕ and flow rate Q while it drops with an increase in particulate volumetric fraction C, Eckert number Ec, Soret number Sr, Schmidt number Sc and viscosity constant. A decrease in temperature is also caused by an increase in the volumetric percentage of nanoparticles. In the pumping portion, there is a decrease in pressure rise; however, this decrease changes to an increase in the increased pumping zone.
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