The paper studies the flow-induced vibration of the volute of a centrifugal pump using the coupled approach of computational fluid dynamics (CFD) and finite element method (FEM). In the present paper, a numerical model of the centrifugal pump for fluid-solid coupling solution was established, and the unsteady flow of the centrifugal pump under different working conditions was simulated by unsteady CFD calculations. Then, the fluctuation pressure on the volute inner surface was extracted and used as the fluid load that induces the volute vibration. The volute vibration response including displacement, and acceleration was discussed based on the results of fluid-solid coupling solutions. The results show that the non-uniform distribution of fluctuation pressure along the volute, and the dominant vibration frequencies of the pump volute are blade frequency and its harmonics, and the minimum vibration and stress of the volute appear at the design condition. Overall, this research gives insight into the flow-induced vibration of centrifugal pump volute casing.