Transportation managers are challenged today by dynamic commercial industries whose supply chains span the globe. The 21st century has ushered in an explosion in electronic commerce, online sales, and data-driven supply chains for products and services. In addition, the world continues to see not only population growth, but also increased urbanization and aging of our population. These changes are shaping where and how consumers demand their products, creating new challenges for transportation and distribution to provide the right time and place utility for customers. For example, transportation managers are seeing a growing need for improved omni-channel supply chain strategies, and innovative ways to deliver products during the “last mile” of delivery. Additionally, growing public concerns and increased policy for environmental and social sustainability are impacting how firms will be able to deliver goods to customers in the decades ahead. Finally, a host of new transportation technologies—such as driverless vehicles, drones, and electric vehicle fleets—appear to offer solutions for the future, but such options still need to be approved by policymakers, integrated into existing supply chains, and aided by management theory on how and when they should be used.Papers for this special issue are due to the guest editors by December 15, 2018.A noninclusive list of appropriate topics for this issue includes: Last-mile delivery strategy and theory developmentThe use of innovative transportation technologies in the 21st centuryInfrastructure-related transportation challenges in emerging nationsImpact of omni-channel and e-commerce growth on the transportation industryEmerging urban logistics challenges and solutionsGlobal transportation risk due to urbanization, population growth, and demographic changeImpacts of evolving transportation regulation (e.g., electronic logbooks)Socially and environmentally sustainable transportation and distribution solutions and designsTransportation investment decision-making in the futureThe proactive role of transportation: influencing public policy and regulationTransportation infrastructure requirements and options for future decades