BACKGROUND: Drug abuse occurs widely in various parts of the world. The drugs that are misused are not only cocaine, or heroin, but also drugs that are commonly prescribed. If you want to get drunk, usually use dextromethorphan (DMP) pills, but now switch to mixing herbal cough medicines with energy drinks. Herbal cough medicine is usually used as a cough reliever, but in teens today, herbal cough medicine is starting to be abused. Mixing energy drinks using herbal cough medicine are motivated by a lack of positive activities or activities, influenced by peers or the environment where the subject lives, lack of application of religious and school education, lack of the role of parents in supervising their children, easy access to herbal cough medicines and drinks energy in large quantities, and the price is cheap. The crime that occurred is not only limited to theft but also drugs and drinking. The only difference, they are not drunk with liquor, but mixed energy drinks with some herbal cough medicine sachets. CASE REPORT: We found a case of acute psychotic disorders due to cannabis use and other psychoactive substances, namely, a mixture of herbal cough medicine containing DMP and energy drinks containing caffeine, after 2 days of use, in a 20-year-old male, found a delusion and hallucinations. CONCLUSIONS: Every use of addictive substances and psychotropic substances will have an impact on life and health. The use of addictive and psychotropic substances when consumed in excess of the dose will damage some organ functions, affect the smooth operation of organ systems, and can also cause acute psychosis.