Psychophysical Studies Research Articles

Symmetry Perception and Psychedelic Experience

This review of symmetry perception has six parts. Psychophysical studies have investigated symmetry perception for over 100 years (part 1). Neuroscientific studies on symmetry perception have accumulated in the last 20 years. Functional MRI and EEG experiments have conclusively shown that regular visual arrangements, such as reflectional symmetry, Glass patterns, and the 17 wallpaper groups all activate the extrastriate visual cortex. This activation generates an event-related potential (ERP) called sustained posterior negativity (SPN). SPN amplitude scales with the degree of regularity in the display, and the SPN is generated whether participants attend to symmetry or not (part 2). It is likely that some forms of symmetry are detected automatically, unconsciously, and pre-attentively (part 3). It might be that the brain is hardwired to detect reflectional symmetry (part 4), and this could contribute to its aesthetic appeal (part 5). Visual symmetry and fractal geometry are prominent in hallucinations induced by the psychedelic drug N,N-dimethyltryptamine (DMT), and visual flicker (part 6). Integrating what we know about symmetry processing with features of induced hallucinations is a new frontier in neuroscience. We propose that the extrastriate cortex can generate aesthetically fascinating symmetrical representations spontaneously, in the absence of external symmetrical stimuli.

The spatial contrast sensitivity function and its neurophysiological bases

Contrast processing is a fundamental function of the visual system, and contrast sensitivity as a function of spatial frequency (CSF) provides critical information about the integrity of the system. Here, we used a novel iPad-based instrument to collect CSFs and fitted the data with a difference of Gaussians model to investigate the neurophysiological bases of the spatial CSF. The reliability of repeat testing within and across sessions was evaluated in a sample of 22 adults for five spatial frequencies (0.41–13 cycles/degree) and two temporal durations (33 and 500 ms). Results demonstrate that the shape of the CSF, lowpass versus bandpass, depends on the temporal stimulus condition. Comparisons with previous psychophysical studies and with single-cell data from macaques and humans indicate that the major portion of the CSF, spatial frequencies >1.5 cycles/degree regardless of temporal condition, is determined by a ‘sustained’ mechanism (presumably parvocellular input to primary visual cortex [V1]). Contrast sensitivity to the lowest spatial frequency tested appears to be generated by a ‘transient’ mechanism (presumably magnocellular input to V1). The model fits support the hypothesis that the high spatial frequency limb of the CSF reflects the receptive field profile of the center mechanism of the smallest cells in the parvocellular pathway. These findings enhance the value of contrast sensitivity testing in general and increase the accessibility of this technique for use by clinicians through implementation on a commercially-available device.

Olfactory recovery following omicron variant infection: a psychophysical prospective case-control study with six-month follow up.

This study aimed to evaluate the recovery of olfactory function at six months in individuals infected with the coronavirus disease 2019 omicron variant, using psychophysical tests. A prospective case-control study that included severe acute respiratory syndrome coronavirus-2 patients infected in February and March 2022 was conducted. Patients underwent the Sniffin' Sticks test within 10 days of infection and again after at least 6 months. The olfactory scores were compared with those of a control group. In all, 102 patients and 120 controls were enrolled in the study. At baseline, 26 patients (25.5 per cent) self-reported smell loss. The median threshold, discrimination and identification score was 33.6 (interquartile range, 12.5) for the cases and 36.5 (interquartile range, 4.38) for the controls (p < 0.001). Based on the threshold, discrimination and identification scores, 12 controls and 34 patients reported olfactory dysfunction (p < 0.001). Eighty cases underwent re-evaluation at six months; the median threshold, discrimination and identification score was 37.1 (interquartile range, 4.75) with no significant differences compared with the controls. Six months after infection, the prevalence of olfactory dysfunction in patients did not differ significantly from the control population.

Heading perception from optic flow occurs at both perceptual representation and working memory stages with EEG evidence

Psychophysical studies have demonstrated that heading perception from optic flow occurs in perceptual and post-perceptual stages. The post-perception stage is a complex concept, containing working memory. The current study examined whether working memory was involved in heading perception from optic flow by asking participants to conduct a heading perception task and recording their scalp EEG. On each trial, an optic flow display was presented, followed by a blank display. Participants were then asked to report their perceived heading. We know that participants would tend to automatically forget previous headings when they learned that previously presented headings were unrelated to the current heading perception to save cognitive resources. As a result, we could not decode previous headings from the EEG data of current trials. More importantly, if we successfully decoded previous headings when the blank display (optic flow) was presented, then working memory (perceptual representation stage) was involved in heading perception. Our results showed that the decoding accuracy was significantly higher than the chance level when the optic flow and blank displays were presented. Therefore, the current study provided electrophysiological evidence that heading perception from optic flow occurred in the perceptual representation and working memory stages, against the previous perceptual claim.

Discrimination tasks in simulated low-dose CT noise.

This study reports the results of a set of discrimination experiments using simulated images that represent the appearance of subtle lesions in low-dose computed tomography (CT) of the lungs. Noise in these images has a characteristic ramp-spectrum before apodization by noise control filters. We consider three specific diagnostic features that determine whether a lesion is considered malignant or benign, two system-resolution levels, and four apodization levels for a total of 24 experimental conditions. The goal of the investigation is to better understand how well human observers perform subtle discrimination tasks like these, and the mechanisms of that performance. We use a forced-choice psychophysical paradigm to estimate observer efficiency and classification images. These measures quantify how effectively subjects can read the images, and how they use images to perform discrimination tasks across the different imaging conditions. The simulated CT images used as stimuli in the psychophysical experiments are generated from high-resolution objects passed through a modulation transfer function (MTF) before down-sampling to the image-pixel grid. Acquisition noise is then added with a ramp noise-power spectrum (NPS), with subsequent smoothing through apodization filters. The features considered are lesion size, indistinct lesion boundary, and a nonuniform lesion interior. System resolution is implemented by an MTF with resolution (10% max.) of 0.47 or 0.58 cyc/mm. Apodization is implemented by a Shepp-Logan filter (Sinc profile) with various cutoffs. Six medically naïve subjects participated in the psychophysical studies, entailing training and testing components for each condition. Training consisted of staircase procedures to find the 80% correct threshold for each subject, and testing involved 2000 psychophysical trials at the threshold value for each subject. Human-observer performance is compared to the Ideal Observer to generate estimates of task efficiency. The significance of imaging factors is assessed using ANOVA. Classification images are used to estimate the linear template weights used by subjects to perform these tasks. Classification-image spectra are used to analyze subject weights in the spatial-frequency domain. Overall, average observer efficiency is relatively low in these experiments (10%-40%) relative to detection and localization studies reported previously. We find significant effects for feature type and apodization level on observer efficiency. Somewhat surprisingly, system resolution is not a significant factor. Efficiency effects of the different features appear to be well explained by the profile of the linear templates in the classification images. Increasingly strong apodization is found to both increase the classification-image weights and to increase the mean-frequency of the classification-image spectra. A secondary analysis of "Unapodized" classification images shows that this is largely due to observers undoing (inverting) the effects of apodization filters. These studies demonstrate that human observers can be relatively inefficient at feature-discrimination tasks in ramp-spectrum noise. Observers appear to be adapting to frequency suppression implemented in apodization filters, but there are residual effects that are not explained by spatial weighting patterns. The studies also suggest that the mechanisms for improving performance through the application of noise-control filters may require further investigation.

Mistaking opposition for autonomy: psychophysical studies on detecting choice bias.

Do people know when they act freely and autonomously versus when their actions are influenced? While the human aspiration to freedom is widespread, little research has investigated how people perceive whether their choices are biased. Here, we explored how actions congruent or incongruent with suggestions are perceived as influenced or free. Across three experiments, participants saw directional stimuli cueing left or right manual responses. They were instructed to follow the cue's suggestion, oppose it or ignore it entirely to make a 'free' choice. We found that we could bias participants' 'free responses' towards adherence or opposition, by making one instruction more frequent than the other. Strikingly, participants consistently reported feeling less influenced by cues to which they responded incongruently, even when response habits effectively biased them towards such opposition behaviour. This effect was so compelling that cues that were frequently presented with the Oppose instruction became systematically judged as having less influence on behaviour, artificially increasing the sense of freedom of choice. Taken together, these findings demonstrate that acting contrarian distorts the perception of autonomy. Crucially, we demonstrate the existence of a novel illusion of freedom evoked by trained opposition. Our results have important implications for understanding mechanisms of persuasion.

Statistically Optimal Cue Integration During Human Spatial Navigation.

In 2007, Cheng and colleagues published their influential review wherein they analyzed the literature on spatial cue interaction during navigation through a Bayesian lens, and concluded that models of optimal cue integration often applied in psychophysical studies could explain cue interaction during navigation. Since then, numerous empirical investigations have been conducted to assess the degree to which human navigators are optimal when integrating multiple spatial cues during a variety of navigation-related tasks. In the current review, we discuss the literature on human cue integration during navigation that has been published since Cheng et al.'s original review. Evidence from most studies demonstrate optimal navigation behavior when humans are presented with multiple spatial cues. However, applications of optimal cue integration models vary in their underlying assumptions (e.g., uninformative priors and decision rules). Furthermore, cue integration behavior depends in part on the nature of the cues being integrated and the navigational task (e.g., homing versus non-home goal localization). We discuss the implications of these models and suggest directions for future research.

Ready to detect a reversal of time's arrow: a psychophysical study using short video clips in daily scenes.

It is generally believed that time flows in one direction and that a reversal of time's arrow would render the external world non-sensical. We evaluated our ability to tell the direction of time's arrow in a wide range of dynamic scenes in our daily life by presenting 360 video clips in the correct or incorrect direction. Participants, who judged the direction in a speeded manner, erred in 39% of trials when a video was played in reverse, but in only 9% when it was played normally. Due to the bias favouring the 'forward' judgement, the reaction was generally faster for the forward response. However, the reaction became paradoxically faster and more synchronous for the detection of reversal in some critical occasions such as forward motion, free fall, diffusion, division and addition of materials by hand. Another experiment with a fraction of the video clips revealed that reversal replay of these videos provided instantaneous evidence strong enough to overtake the forward judgement bias. We suggest that our brain is equipped with a system that predicts how the external organisms behave or move in these critical occasions and that the prediction error of the system contributes to the fast 'reversal' detection.

"I see where this is going": a psychophysical study of directional mid-air haptics and apparent tactile motion.

Mid-air haptic technology can render a plethora of tactile sensations including points, lines, shapes, and textures. To do so, one requires increasingly complex haptic displays. Meanwhile, tactile illusions have had widespread success in the development of contact and wearable haptic displays. In this article, we exploit the apparent tactile motion illusion to display mid-air haptic directional lines; a prerequisite for the rendering of shapes and icons. We present two pilot studies and a psychophysical study that contrasts a dynamic tactile pointer (DTP) to an apparent tactile pointer (ATP) in terms of direction recognition. To that end, we identify optimal duration and direction parameters for both DTP and ATP mid-air haptic lines and discuss the implications of our findings with respect to haptic feedback design, and device complexity.

Perceptual learning: Breaking specificity by variability

A new psychophysical study in humans suggests that increasing the variability of task-irrelevant features during training enhances the generalization of visual perceptual learning to untrained stimuli and locations.

Short periods of perinatal acoustic experience alter the developmental trajectory of auditory cortex

Compared to hearing subjects, psychophysical studies have revealed specific superior visual abilities following hearing loss early in development. The neural substrate for these superior abilities resides in auditory cortex that have been reorganized through crossmodal plasticity. Furthermore, the cartography of auditory cortex is altered following the loss of auditory input early in life. This study examined how perinatal exposure to brief periods of acoustic stimulation alters the developmental trajectory of auditory cortex. Movement detection, localization in the visual periphery, and face discrimination learning are superior in congenitally deaf cats. To examine the role of acoustic experience in mediating these enhanced functions, hearing animals were chemically deafened at increasing ages postnatal. Animals had 1–16 weeks of acoustic exposure prior to deafness onset. Overall, &amp;gt;9 weeks of acoustic experience resulted in no enhanced visual abilities. With &amp;gt;4 weeks of acoustic exposure, enhanced motion detection was not evident. As acoustic experience increased during development, the overall size of auditory cortex, and the size of individual auditory areas also expanded. These results demonstrate that increasingly longer periods of perinatal acoustic experience result in reduced enhanced visual abilities and an increased size of auditory cortex.

Omit needless words: Sentence length perception.

Short sentences improve readability. Short sentences also promote social justice through accessibility and inclusiveness. Despite this, much remains unknown about sentence length perception-an important factor in producing readable writing. Accordingly, we conducted a psychophysical study using procedures from Signal Detection Theory to examine sentence length perception in naive adults. Participants viewed real-world full-page text samples and judged whether a bolded target sentence contained more or fewer than 17 words. The experiment yielded four findings. First, naïve adults perceived sentence length in real-world text samples quickly (median = 300-400 ms) and precisely (median = ~90% correct). Second, flipping real-world text samples upside-down generated no reaction-time cost and nearly no loss in the precision of sentence length perception. This differs from the large inversion effects that characterize other highly practiced, real-world perceptual tasks involving canonically oriented stimuli, most notably face perception and reading. Third, participants significantly underestimated the length of mirror-reversed sentences-but not upside-down, nor standard sentences. This finding parallels participants' familiarity with commonly occurring left-justified right-ragged text, and suggests a novel demonstration of left-lateralized anchoring in scene syntax. Fourth, error patterns demonstrated that participants achieved their high speed, high precision sentence-length judgments by heuristically counting text lines, not by explicitly counting words. This suggests practical advice for writing instructors to offer students. When copy editing, students can quickly and precisely identify their long sentences via a line-counting heuristic, e.g., "a 17-word sentence spans about 1.5 text lines". Students can subsequently improve a long sentence's readability and inclusiveness by omitting needless words.

Modifying Deutsch's scale illusion for application in music.

Deutsch's scale illusion demonstrates that the overall pitch range is the preferred organization when in competition with both local (note-to-note) pitch proximity and laterality (differences in the input ear). Such intricate factors can make it difficult to mimic this illusion. If a note is under a condition in which grouping by the overall pitch range and the local pitch proximity do not conflict, we hypothesized that an illusion would be perceived simply as the result of the competition between pitch proximity and laterality. In this paper, we aimed to replicate such a condition by modifying Deutsch's scale illusion. Psychophysical studies were conducted with healthy subjects. In the first half of the study, the C major scale with successive tones was presented in ascending form, alternating between the right and left ears; counterpart notes were simultaneously presented to the opposite ear, and the subjects were asked to listen to these dichotic tone patterns. Several counterpart notes were applied; we found that when the sequences of counterpart notes were close in note-to-note pitch proximity and were not overlapped with the ascending scale in pitch, the subjects appeared to perceive the scale clearly. In the latter half of the study, we applied this condition in music and devised auditory illusions such that melodies of the passages of "Lightly Row," "Cherry Blossoms," and "Jingle Bells" were perceived by listening to "jagged" dichotic tone patterns. The method we described in this paper is simple, and it is possible to easily create auditory illusions in music by applying our method.

The lateralized flash-lag illusion: A psychophysical and pupillometry study

The flash-lag illusion (FLI) is a visual phenomenon where a flashed object, either co-localized or in physical alignment with another continuously moving object, is perceived to lag behind the path of the moving object. In the present study, we reveal an anisotropy of the FLI between the lateral visual fields that was expressed psychophysically as different points of subjective equality, depending on the hemifield in which the stimuli appeared. Specifically, the study confirmed that, as seen in two previous studies, the FLI was significantly larger in the left visual field (LVF) than in the right (RVF). In addition, pupil dilations were larger in the RVF than in the LVF as well as returning to baseline levels more rapidly in the LVF. We interpret these findings as converging on revealing more efficient spatial and attentional processing and, in turn, extrapolation of motion in the LVF/right hemisphere than in the RVF/left hemisphere.

Bayesian surprise shapes neural responses in somatosensory cortical circuits.

Numerous psychophysical studies show that Bayesian inference governs sensory decision-making; however, the specific neural circuitry underlying this probabilistic mechanism remains unclear. We record extracellular neural activity along the somatosensory pathway of mice while delivering sensory stimulation paradigms designed to isolate the response to the surprise generated by Bayesian inference. Our results demonstrate that laminar cortical circuits in early sensory areas encode Bayesian surprise. Systematic sensitivity to surprise is not identified in the somatosensory thalamus, rather emerging in the primary (S1) and secondary (S2) somatosensory cortices. Multiunit spiking activity and evoked potentials in layer 6 of these regions exhibit the highest sensitivity to surprise. Gamma power in S1 layer 2/3 exhibits an NMDAR-dependent scaling with surprise, as does alpha power in layers 2/3 and 6 of S2. These results show a precise spatiotemporal neural representation of Bayesian surprise and suggest that Bayesian inference is a fundamental component of cortical processing.

Dissociation in neuronal encoding of object versus surface motion in the primate brain

A paradox exists in our understanding of motion processing in the primate visual system: neurons in the dorsal motion processing stream often strikingly fail to encode long-range and perceptually salient jumps of a moving stimulus. Psychophysical studies suggest that such long-range motion, which requires integration over more distant parts of the visual field, may be based on higher-order motion processing mechanisms that rely on feature or object tracking. Here, we demonstrate that ventral visual area V4, long recognized as critical for processing static scenes, includes neurons that maintain direction selectivity for long-range motion, even when conflicting local motion is present. These V4 neurons exhibit specific selectivity for the motion of objects, i.e., targets with defined boundaries, rather than the motion of surfaces behind apertures, and are selective for direction of motion over a broad range of spatial displacements and defined by a variety of features. Motion direction at a range of speeds can be accurately decoded on single trials from the activity of just a few V4 neurons. Thus, our results identify a novel motion computation in the ventral stream that is strikingly different from, and complementary to, the well-established system in the dorsal stream, and they support the hypothesis that the ventral stream system interacts with the dorsal stream to achieve the higher level of abstraction critical for tracking dynamic objects.

Resolution Aspects for Near-Field Projections

This work intends to define the resolution requirements for near-field projections in a psycho-physical study design to evaluate the participants’ perception under the influence of different ambient lighting levels and various viewing distances. The variation in ambient lighting and viewing distances relates to various daytime and critical distances in urban environments. The application of near-field projections increases the popularity of communication- or safety-relevant projections, such as for automated vehicles. However, previous studies in the filming industry have shown that the resolution requirements differ depending on the application. In this work, a field study design presents an experimental approach to define a perceived resolution on the street surface in the near field around the vehicle. Furthermore, the study evaluates the influence of viewing distance, ambient lighting and projection content on the perceived resolution in detail. The results reveal a significant dependency on ambient lighting (p &lt; 0.05). Furthermore, this work states that the symbol-based projection has lower resolution requirements, e.g., a viewing distance of 1 m and 3 m results in a 2 pixels per degree resolution compared to the text-based projection in the parking garage scenario. Nevertheless, in the dusk/dawn scenario, the perceived resolution can be grouped for viewing distances above 1 m for content-independent projections.

Revisiting the color-motion asynchrony.

Color-motion asynchrony (CMA) refers to an illusion in which we perceive a change in color earlier than a change in motion direction when the two changes occur simultaneously. This phenomenon may indicate that color is processed earlier than motion in the visual system. However, the very existence of CMA is under question owing to contradictory findings and methodological deficits in previous studies. Here, we used both the motion and color correspondence tasks (experiment 1) and the temporal order judgment (TOJ) task (experiment 2) to re-examine CMA. Colored dots moved in one direction and changed their color/direction at some time, whereas the relative timing between color and direction changes varied across trials. In the correspondence task, participants reported which direction/color of dots with a particular color/direction lasted longer, the one before or after the change? In the TOJ task, participants reported whether the change in color or the change in motion direction occurred earlier. Results indicated that participants perceived the change in color earlier than the change in motion direction in either the motion or color correspondence task, with a stronger asynchrony in the former. In the TOJ task, although participants showed no difference in psychophysical measures, they responded faster when the change in color occurred before (versus after) the change in direction. Drift-diffusion modeling (DDM) revealed a lower decision threshold when the change in color occurred before (versus after) the change in direction, indicating less cautiousness was excised in judgment when the color changed earlier. These results confirmed the veracity of CMA in different tasks and point to the viability of analyzing response times in traditional psychophysical studies.

Coulomb Calligraphy

The equilibrium configurations of N Coulomb charges confined by a harmonic potential in two dimensions are found to exhibit a wide variety of patterns that are pleasing to the eye, when adjacent points are joined up. We present a selection of these for N=50. The patterns are reminiscent of early examples of algorithmic or computer-generated art, and might be of use for psycho-physical studies of the perception of structure and randomness. They could also find applications in the generation of recognisable symbols in an alphabet of infinite extent, easily generated and varied using the software that is provided here.

‘Tasting Imagination’: What Role Chemosensory Mental Imagery in Multisensory Flavour Perception?

A number of perplexing phenomena in the area of olfactory/flavour perception may fruitfully be explained by the suggestion that chemosensory mental imagery can be triggered automatically by perceptual inputs. In particular, the disconnect between the seemingly limited ability of participants in chemosensory psychophysics studies to distinguish more than two or three odorants in mixtures and the rich and detailed flavour descriptions that are sometimes reported by wine experts; the absence of awareness of chemosensory loss in many elderly individuals; and the insensitivity of the odour-induced taste enhancement (OITE) effect to the mode of presentation of olfactory stimuli (i.e., orthonasal or retronasal). The suggestion made here is that the theory of predictive coding, developed first in the visual modality, be extended to chemosensation. This may provide a fruitful way of thinking about the interaction between mental imagery and perception in the experience of aromas and flavours. Accepting such a suggestion also raises some important questions concerning the ecological validity/meaning of much of the chemosensory psychophysics literature that has been published to date.