The need to study the impact of art therapy, in particular music therapy, on the psycho-emotional state of children and adolescents with cancer is dictated by the high prevalence of mental disorders during hospitalization. Purpose: to analyze the literature to study the impact of music therapy on the psycho-emotional state of children and adolescents with cancer during treatment. General information. The most common symptoms experienced by children and adolescents undergoing treatment for cancer are depression, anxiety, pain associated with diagnostic procedures and treatment, nausea and fatigue, sleep disturbances and fatigue. Variations of art therapy using active and receptive methods of music therapy effectively influence the psycho-emotional status of patients, help children get rid of feelings of fear and cope with their anxiety, promote wellness, stress management, pain relief and more. The use of music therapy methods normalizes the psychosomatic state. The goal of psychotherapeutic work with adolescents and children with cancer is, first of all, prevention and correction of psychopathological reactions. Timely psychotherapy provided to cancer patients in childhood will help harmonize the psycho-emotional state associated with the treatment, especially after mutilating operations. The technique is universal and integrative; it can be successfully used in the treatment of many psychological disorders, as well as integrated and combined with other therapeutic approaches (body-oriented approach, drawing, dance-movement method, etc.). To reduce the incidence of mental pathology after illness and achieve its maximum compensation, a multidisciplinary approach is required.