The purpose of this research is to investigate the mediating effect of active aging in the relationship between depression and ego-integrity of death anxiety on baby boom generation. For this purpose, the data were collected using death anxiety, active aging, depression, and ego-integrity measures from 600 adult men and women living in the baby boom generation (1955-1963) nationwide. The results indicated that first, there was a significant correlation between the main variables of this study. Second, when death anxiety effect on depression, active aging has a significant partial mediating effect. Third, when death anxiety affects on ego-integrity, active aging has a significant partial mediating effect. Through this study, psychological intervention programs and policy support measures to reduce depression of baby boomers and increase ego-integrity were examined. Lastly, this study ends with discussions of implications, limitations, and suggestion.